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RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.014
  
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sciencedirect.com/science/article/pii/S1535610825004064
Oct 2025
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Protocol to identify and sort antigen-specific B cells from Plasmodium-infected mice

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.xpro.2025.104129
  
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sciencedirect.com/science/article/pii/S2666166725005350
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.008
  
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sciencedirect.com/science/article/pii/S1074761325004194
Jun 2025
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Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy

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1. scibot 11 Jun 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2054
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12127800/
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RORγt is crucial for gut homeostasis by regulating the expression of HB-EGF rather than IL-22 in activated ILC3s

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  DOI: 10.1016/j.celrep.2025.115793
  
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cell.com/cell-reports/abstract/S2211-1247(25)00564-9
May 2025
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A CD4+ T cell-intrinsic complement C5aR2-prostacyclin-IL-1R2 axis orchestrates Th1 cell contraction

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1. scibot 31 May 2025
  
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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1. scibot 29 May 2025
  
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Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

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1. scibot 28 May 2025
  
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  DOI: 10.7554/eLife.101714
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12097789/
Apr 2025
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Systemic 4-1BB stimulation augments extrafollicular memory B cell formation and recall responses during Plasmodium infection

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115528
  
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sciencedirect.com/science/article/pii/S2211124725002992
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Somatic Miwi2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis

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  DOI: 10.1016/j.isci.2025.112291
  
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sciencedirect.com/science/article/pii/S2589004225005528
Feb 2025
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Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.cell.2025.01.021
  
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sciencedirect.com/science/article/pii/S0092867425000509
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MAIT cells protect against sterile lung injury

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1. scibot 07 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115275
  
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sciencedirect.com/science/article/pii/S2211124725000464
Jan 2025
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Menin orchestrates macrophage reprogramming to maintain the pulmonary immune homeostasis

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115219
  
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sciencedirect.com/science/article/pii/S2211124724015705
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Bone marrow mesenchymal stromal cells support translation in refractory acute myeloid leukemia

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115151
  
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sciencedirect.com/science/article/pii/S221112472401502X
Dec 2024
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YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

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1. scibot 18 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.007
  
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sciencedirect.com/science/article/pii/S0092867424013242
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IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114948
  
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sciencedirect.com/science/article/pii/S2211124724012993
Sep 2024
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Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.010
  
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sciencedirect.com/science/article/pii/S1550413124003620
Aug 2024
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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes

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1. scibot 30 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.024
  
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sciencedirect.com/science/article/pii/S107476132400373X
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Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.devcel.2024.08.003
  
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sciencedirect.com/science/article/pii/S1534580724004866
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Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.cmet.2024.07.017
  
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sciencedirect.com/science/article/pii/S1550413124002882
Jul 2024
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Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.neuron.2024.06.017
  
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sciencedirect.com/science/article/pii/S0896627324004525
Jun 2024
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Therapeutic potential of co-signaling receptor modulation in hepatitis B

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.038
  
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sciencedirect.com/science/article/pii/S0092867424005828
May 2024
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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

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sciencedirect.com/science/article/pii/S1074761324002243
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Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling

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1. scibot 09 May 2024
  
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  DOI: 10.1016/j.devcel.2024.04.015
  
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sciencedirect.com/science/article/pii/S1534580724002685
Apr 2024
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Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program

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1. scibot 24 Apr 2024
  
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sciencedirect.com/science/article/pii/S0092867424003489
Mar 2024
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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

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1. scibot 13 Mar 2024
  
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Jun 2023
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Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s

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1. scibot 09 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112610
  
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Feb 2023
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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection

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1. scibot 23 Feb 2023
  
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sciencedirect.com/science/article/pii/S1074761323000419
Oct 2022
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Ketogenic diet uncovers differential metabolic plasticity of brain cells

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1. scibot 25 Oct 2022
  
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  DOI: 10.1126/sciadv.abo7639
  
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science.org/doi/10.1126/sciadv.abo7639
Sep 2022
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Yin and Yang of Cannabinoid CB1 receptor: CB1 Deletion in Immune Cells Causes Exacerbation While CB1 Deletion in Non-immune Cells Attenuates Obesity

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Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn

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  DOI: 10.1016/j.isci.2022.104963
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9442361/
Feb 2022
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GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA

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sciencedirect.com/science/article/pii/S009286742200068X
Jan 2022
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Polyamine import and accumulation causes immunomodulation in macrophages engulfing apoptotic cells

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1. scibot 16 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110222
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8859864/
Oct 2021
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Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice

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1. scibot 27 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109889
  
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sciencedirect.com/science/article/pii/S2211124721013590
Sep 2021
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Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response

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1. scibot 15 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.017
  
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Evaluation of Marijuana Compounds on Neuroimmune Endpoints in Experimental Autoimmune Encephalomyelitis

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  DOI: 10.1016/j.chom.2018.11.011
  
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Targeted Delivery of Antigen to Activated CD169+ Macrophages Induces Bias for Expansion of CD8+ T Cells

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EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection

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  DOI: 10.1016/j.celrep.2019.06.020
  
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Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens

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  DOI: 10.1016/j.celrep.2019.08.038
  
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A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

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Nov 2018
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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

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