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The transcription factor BACH1 couples chromatin priming and repression to enable macrophage plasticity and adaptation

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1. scibot 20 Jul 2026
  
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sciencedirect.com/science/article/pii/S1074761326002736
Jul 2026
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B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

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1. scibot 05 Jul 2026
  
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sciencedirect.com/science/article/pii/S1074761326002542
Jun 2026
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Oat-β-glucan potentiates anti-PD-1 efficacy through Faecalibacterium prausnitzii-derived butyrate and indole-3-propionic acid

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1. scibot 03 Jun 2026
  
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sciencedirect.com/science/article/pii/S1931312826001782
May 2026
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Circulating extracellular vesicle microRNAs mediate immune modulation of social behavior in male mice

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1. scibot 30 May 2026
  
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  DOI: 10.1038/s41467-026-70469-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13216276/
Apr 2026
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Palmitic acid reprograms neutrophils to compromise vascular integrity and promote breast cancer lung metastasis

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1. scibot 25 Apr 2026
  
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sciencedirect.com/science/article/pii/S1074761326001378
Mar 2026
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β-hydroxybutyrate enhances the metabolic fitness of CAR T cells in cancer

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1. scibot 10 Mar 2026
  
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sciencedirect.com/science/article/pii/S0092867426001698
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Hematopoietic stem cells activate a latent differentiation pathway to facilitate recovery after 5-fluorouracil-induced myeloablation

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1. scibot 03 Mar 2026
  
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sciencedirect.com/science/article/pii/S1534580726000432
Feb 2026
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The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors

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1. scibot 19 Feb 2026
  
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sciencedirect.com/science/article/pii/S107476132600035X
Jan 2026
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Controlled pyroptosis of engineered macrophages enables biphasic antitumor via the release of oncolytic bacteria and inflammatory signals

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116918
  
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sciencedirect.com/science/article/pii/S2211124725016900
Oct 2025
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TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis

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1. scibot 23 Oct 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-4224
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618269/
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CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116351
  
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sciencedirect.com/science/article/pii/S2211124725011222
Sep 2025
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Red Blood Cell-Mediated Enhancement of Hematopoietic Stem Cell Functions via a Hes1-Dependent Pathway

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1. scibot 18 Sep 2025
  
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  DOI: 10.1096/fj.202500885R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500885R
Aug 2025
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Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102307
  
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sciencedirect.com/science/article/pii/S2666379125003805
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Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates pancreatic ductal adenocarcinoma development

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.cmet.2025.07.008
  
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sciencedirect.com/science/article/pii/S1550413125003353
Jul 2025
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Manufacturing of CRISPR-edited primary mouse CAR T cells for cancer immunotherapy

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1. scibot 29 Jul 2025
  
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  DOI: 10.1038/s41596-025-01208-x
  
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nature.com/articles/s41596-025-01208-x
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Cognate interaction-dependent pathogenicity of meningeal B cells drives neuroinflammation relapse

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.016
  
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sciencedirect.com/science/article/pii/S1074761325002857
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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Protocol to study phagocytosis of apoptotic murine splenocytes by syngeneic antigen-presenting cells in vitro

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1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.xpro.2025.103903
  
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sciencedirect.com/science/article/pii/S2666166725003090
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The IL-33/ST2 axis and tissue Treg maintain epithelial homeostasis and restrain cancer development in the skin

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115837
  
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sciencedirect.com/science/article/pii/S2211124725006084
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Protocol to study in vivo organ-specific migration of apoptotic splenocytes in mice with tumor and immune checkpoint inhibitor-induced colitis

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.xpro.2025.103878
  
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sciencedirect.com/science/article/pii/S2666166725002849
May 2025
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Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.030
  
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sciencedirect.com/science/article/pii/S1074761325001931
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Universal fibroblasts across tissues can differentiate into niche cells for hematopoietic stem cells

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  DOI: 10.1016/j.celrep.2025.115620
  
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sciencedirect.com/science/article/pii/S2211124725003912
Apr 2025
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Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes

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1. scibot 19 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115571
  
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sciencedirect.com/science/article/pii/S2211124725003420
Mar 2025
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Collaboration between interleukin-7 and -15 enables adaptation of tissue-resident and circulating memory CD8+ T cells to cytokine deficiency

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.009
  
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sciencedirect.com/science/article/pii/S1074761325000767
Feb 2025
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Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101976
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970324/
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Mechanistic insight into the induction of liver tissue-resident memory CD8+ T cells by glycolipid-peptide vaccination

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115295
  
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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1. scibot 11 Feb 2025
  
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sciencedirect.com/science/article/pii/S1535610825000224
Dec 2024
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Different effects of fatty acid oxidation on hematopoietic stem cells based on age and diet

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.stem.2024.11.014
  
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sciencedirect.com/science/article/pii/S1934590924004132
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Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence

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1. scibot 21 Dec 2024
  
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sciencedirect.com/science/article/pii/S1074761324005223
Aug 2024
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Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells

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sciencedirect.com/science/article/pii/S1097276524006191
Jul 2024
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Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner

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sciencedirect.com/science/article/pii/S2211124724008714
Dec 2023
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Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy

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sciencedirect.com/science/article/pii/S2666379123005633
Oct 2023
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Variable staphyloxanthin production by Staphylococcus aureus drives strain-dependent effects on diabetic wound-healing outcomes

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113281
  
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sciencedirect.com/science/article/pii/S2211124723012937
Aug 2023
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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

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1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113013
  
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sciencedirect.com/science/article/pii/S2211124723010240
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Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112946
  
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52.53.155.43/4490579c6cee094eabc4311188483ae5f60f6c44/PIIS2211124723009579-html.html
Feb 2023
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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection

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1. scibot 23 Feb 2023
  
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  RRID:AB_313494
  
  DOI: 10.1016/j.immuni.2023.01.029
  
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sciencedirect.com/science/article/pii/S1074761323000419
May 2022
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Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

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1. scibot 11 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110798
  
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sciencedirect.com/science/article/pii/S2211124722005654
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Nasally-delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron

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1. scibot 06 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110799
  
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sciencedirect.com/science/article/pii/S2211124722005666
Dec 2021
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Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases

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1. scibot 11 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103445
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8633978/
Nov 2021
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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109916
  
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sciencedirect.com/science/article/pii/S2211124721013899
Aug 2021
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Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

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1. scibot 27 Aug 2021
  
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  DOI: 10.1016/j.stem.2021.07.011
  
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sciencedirect.com/science/article/pii/S1934590921002964
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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

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1. scibot 05 Aug 2021
  
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  DOI: 10.7554/eLife.69975
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
Feb 2021
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The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation

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1. scibot 28 Feb 2021
  
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  DOI: 10.1016/j.immuni.2020.12.010
  
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sciencedirect.com/science/article/pii/S1074761320305380
Sep 2020
elifesciences.org elifesciences.org

Capturing change in clonal composition amongst single mouse germinal centers

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1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.33051
  
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elifesciences.org/articles/33051
Jan 2020
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Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.10.086
  
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sciencedirect.com/science/article/pii/S2211124719314081
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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.08.086
  
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sciencedirect.com/science/article/pii/S2211124719311489
Nov 2018
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Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867418311838
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Untitled document

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761318303881
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6070335/
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Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818300060
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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610817305123
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Segmented Filamentous Bacteria Provoke Lung Autoimmunity by Inducing Gut-Lung Axis Th17 Cells Expressing Dual TCRs

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1931312817304420
Nov 2017
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Clonal Evolution of Autoreactive Germinal Centers

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1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0092867417308334