63 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
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    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.cmet.2024.06.006

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    sciencedirect.com/science/article/pii/S1550413124002316
  3. May 2024
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    SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production
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    1. scibot 21 May 2024
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      DOI: 10.1016/j.stem.2024.04.023

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    sciencedirect.com/science/article/pii/S1934590924001760
  5. Apr 2024
  6. elifesciences.org elifesciences.org
    Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis
    1
    1. scibot 10 Apr 2024
      RRID:AB_313683

      DOI: 10.7554/eLife.87674

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    elifesciences.org/articles/87674
  7. Feb 2024
  8. dx.doi.org dx.doi.org
    The influence of maternal high fat diet during lactation on offspring hematopoietic priming
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    1. scibot 27 Feb 2024
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      DOI: 10.1210/endocr/bqad182

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    dx.doi.org/10.1210/endocr/bqad182
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    An iron rheostat controls hematopoietic stem cell fate
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    1. scibot 23 Feb 2024
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    sciencedirect.com/science/article/pii/S1934590924000419
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    Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48
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    1. scibot 22 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001281
  11. Jan 2024
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    Deciphering the metabolic heterogeneity of hematopoietic stem cells with single-cell resolution
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    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.005

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    sciencedirect.com/science/article/pii/S1550413123004564
  13. Oct 2023
  14. www.embopress.org www.embopress.org
    Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL-1R/TLR signals
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    1. scibot 27 Oct 2023
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      DOI: 10.15252/embr.202357485

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    embopress.org/doi/10.15252/embr.202357485
  15. 52.53.155.43 52.53.155.43
    Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    1
    1. scibot 20 Oct 2023
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      DOI: 10.1101/2023.09.04.556230

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    52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
  16. Sep 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for high-sensitivity western blot on murine hematopoietic stem cells
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.xpro.2023.102578

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    ncbi.nlm.nih.gov/pmc/articles/PMC10519847/
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    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
    1
    1. scibot 01 Sep 2023
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    sciencedirect.com/science/article/pii/S2211124723010586
  19. Jun 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
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    1. scibot 24 Jun 2023
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      DOI: 10.7554/eLife.83004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
  21. www.sciencedirect.com www.sciencedirect.com
    Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner
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    1. scibot 22 Jun 2023
      RRID:AB_313683

      DOI: 10.1016/j.molcel.2023.05.035

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    sciencedirect.com/science/article/pii/S1097276523004197
  22. May 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.stem.2023.04.005

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    sciencedirect.com/science/article/pii/S1934590923001236
  24. Apr 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.stem.2023.03.005

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    sciencedirect.com/science/article/pii/S1934590923000760
  26. Mar 2023
  27. europepmc.org europepmc.org
    Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.stem.2023.02.010

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    europepmc.org/article/med/36948186
  28. Feb 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells
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    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112105

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    sciencedirect.com/science/article/pii/S221112472300116X
  30. www.sciencedirect.com www.sciencedirect.com
    A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
    1
    1. scibot 10 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112099

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    sciencedirect.com/science/article/pii/S2211124723001109
  31. Jan 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.stem.2022.12.014

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    sciencedirect.com/science/article/pii/S1934590922004982
  33. Dec 2022
  34. www.sciencedirect.com www.sciencedirect.com
    A culture platform to study quiescent hematopoietic stem cells following genome editing
    1
    1. scibot 06 Dec 2022
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      DOI: 10.1016/j.crmeth.2022.100354

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    sciencedirect.com/science/article/pii/S266723752200251X
  35. Oct 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111447

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    sciencedirect.com/science/article/pii/S2211124722012888
  37. Jul 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis
    1
    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.stem.2022.06.004

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    sciencedirect.com/science/article/pii/S1934590922002533
  39. Jun 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Fast and high-fidelity in situ 3D imaging protocol for stem cells and niche components for mouse organs and tissues
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    1. scibot 18 Jun 2022
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      DOI: 10.1016/j.xpro.2022.101483

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    sciencedirect.com/science/article/pii/S266616672200363X
  41. www.sciencedirect.com www.sciencedirect.com
    A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis
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    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.cmet.2022.05.009

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    sciencedirect.com/science/article/pii/S1550413122001917
  42. May 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    1. scibot 11 May 2022
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      DOI: 10.1126/sciadv.abm9987

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    ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
  44. Apr 2022
  45. www.science.org www.science.org
    A somatic mutation in moesin drives progression into acute myeloid leukemia
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    1. scibot 30 Apr 2022
      RRID:AB_313683

      DOI: 10.1126/sciadv.abm9987

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    science.org/doi/full/10.1126/sciadv.abm9987
  46. Nov 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell size is a determinant of stem cell potential during aging
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    1. scibot 24 Nov 2021
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      DOI: 10.1126/sciadv.abk0271

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    ncbi.nlm.nih.gov/pmc/articles/PMC8589318/
  48. www.sciencedirect.com www.sciencedirect.com
    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110058

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    sciencedirect.com/science/article/pii/S2211124721015448
  49. Sep 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
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    1. scibot 01 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109626

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    sciencedirect.com/science/article/pii/S2211124721010640
  51. Aug 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging
    1
    1. scibot 16 Aug 2021
      RRID:AB_313683

      DOI: 10.1016/j.stem.2021.07.009

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    sciencedirect.com/science/article/pii/S1934590921002940
  53. europepmc.org europepmc.org
    Untitled document
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    1. scibot 07 Aug 2021
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      DOI: 10.7554/eLife.41258

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    europepmc.org/articles/PMC6298771/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
    1
    1. scibot 05 Aug 2021
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      DOI: 10.7554/eLife.69975

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    ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
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      DOI: 10.1016/j.stem.2018.10.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224657/
  56. Jul 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Apelin+ Endothelial Niche Cells Control Hematopoiesis and Mediate Vascular Regeneration after Myeloablative Injury
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      DOI: 10.1016/j.stem.2019.10.006

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    sciencedirect.com/science/article/pii/S1934590919304278
  58. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging
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      DOI: 10.1016/j.celrep.2018.12.101

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    sciencedirect.com/science/article/pii/S221112471832076X
  59. www.sciencedirect.com www.sciencedirect.com
    JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells
    1
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      DOI: 10.1016/j.ccell.2018.10.008

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    sciencedirect.com/science/article/pii/S1535610818304744
  60. May 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
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    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.08.001

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    sciencedirect.com/science/article/pii/S1934590920303970
  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
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    1. scibot 01 Apr 2021
      RRID:AB_313683

      DOI: 10.1016/j.celrep.2021.108922

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    sciencedirect.com/science/article/pii/S2211124721002369
  64. Feb 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
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      DOI: 10.1016/j.celrep.2021.108751

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    sciencedirect.com/science/article/pii/S2211124721000644
  66. www.sciencedirect.com www.sciencedirect.com
    The autism-related protein CHD8 contributes to the stemness and differentiation of mouse hematopoietic stem cells
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    1. scibot 09 Feb 2021
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      DOI: 10.1016/j.celrep.2021.108688

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    sciencedirect.com/science/article/pii/S2211124721000012
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
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  68. Oct 2020
  69. www.cell.com www.cell.com
    Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding
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  70. Sep 2020
  71. www.sciencedirect.com www.sciencedirect.com
    Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression
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  72. elifesciences.org elifesciences.org
    Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging
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  73. www.sciencedirect.com www.sciencedirect.com
    Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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  76. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells
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  77. Jan 2020
  78. www.sciencedirect.com www.sciencedirect.com
    Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
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    Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
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    Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo
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    Plasma Cells Are Obligate Effectors of Enhanced Myelopoiesis in Aging Bone Marrow
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    Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses
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      DOI: 10.1016/j.cell.2019.07.047

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  83. www.sciencedirect.com www.sciencedirect.com
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  85. www.sciencedirect.com www.sciencedirect.com
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  87. Nov 2018
  88. www.sciencedirect.com www.sciencedirect.com
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Majority of CD45– Ter119– CD31– Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors
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  90. www.sciencedirect.com www.sciencedirect.com
    CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine
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    Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress
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    Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches
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  93. www.sciencedirect.com www.sciencedirect.com
    A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion
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