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Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102324
  
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sciencedirect.com/science/article/pii/S2666379125003970
Aug 2025
www.tandfonline.com www.tandfonline.com

A preclinical model for the identification of therapeutically active transgenes in local cancer immunotherapy

1
1. scibot 21 Aug 2025
  
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  DOI: 10.1080/2162402X.2025.2543620
  
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tandfonline.com/doi/full/10.1080/2162402X.2025.2543620
academic.oup.com academic.oup.com

TRPV1+ neurons promote cutaneous immunity against Schistosoma mansoni

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1. scibot 15 Aug 2025
  
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  RRID:AB_315404
  
  DOI: 10.1093/jimmun/vkaf141
  
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academic.oup.com/jimmunol/advance-article/doi/10.1093/jimmun/vkaf141/8225876
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Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates pancreatic ductal adenocarcinoma development

1
1. scibot 13 Aug 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.cmet.2025.07.008
  
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sciencedirect.com/science/article/pii/S1550413125003353
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Design of soluble Notch agonists that drive T cell development and boost immunity

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1. scibot 05 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.009
  
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sciencedirect.com/science/article/pii/S0092867425007986
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HPV16-Expressing Tumors Release Multiple IL1 Ligands to Orchestrate Systemic Immunosuppression Whose Disruption Enables Efficacy of a Therapeutic Vaccine

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1. scibot 08 Jul 2025
  
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  RRID:AB_315404
  
  DOI: 10.1158/2159-8290.CD-25-0382
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223509/
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

1
1. scibot 08 Jul 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling

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1. scibot 13 Jun 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.ccell.2025.05.011
  
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sciencedirect.com/science/article/pii/S153561082500220X
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Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells

1
1. scibot 11 Jun 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.molcel.2025.05.019
  
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sciencedirect.com/science/article/pii/S1097276525004587
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

1
1. scibot 03 Jun 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PIM kinase control of CD8 T cell protein synthesis and cell trafficking

1
1. scibot 22 May 2025
  
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  RRID:AB_315404
  
  DOI: 10.7554/eLife.98622
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074636/
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Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway

1
1. scibot 22 May 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2025.115733
  
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sciencedirect.com/science/article/pii/S2211124725005042
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Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells

1
1. scibot 17 May 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.immuni.2025.04.027
  
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sciencedirect.com/science/article/pii/S1074761325001906
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Combination therapy with alisertib enhances the anti-tumor immunity induced by a liver cancer vaccine

1
1. scibot 18 Apr 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.isci.2025.112120
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11995041/
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 04 Apr 2025
  
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  RRID:AB_315404
  
  DOI: 10.1158/2326-6066.cir-24-0834
  
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52.53.155.43/b8eb1cd1446295bdd52d11650093cdf439d34361/PDF-html.html
Mar 2025
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BET inhibitor in combination with BCG vaccine enhances antitumor efficacy and orchestrates T cell reprogramming for melanoma

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1. scibot 20 Mar 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.xcrm.2025.101995
  
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sciencedirect.com/science/article/pii/S2666379125000680
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti-Tumor Effector Cytotoxic T Cells

1
1. scibot 13 Mar 2025
  
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  RRID:AB_315404
  
  DOI: 10.1002/advs.202410241
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202410241
Feb 2025
52.53.155.43 52.53.155.43

cir-24-0484-html.html

1
1. scibot 20 Feb 2025
  
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  RRID:AB_315404
  
  DOI: 10.1158/2326-6066.CIR-24-0484
  
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52.53.155.43/907147dca7b0350ae4d97a7f04ddc5ad1538a91e/cir-24-0484-html.html
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The impact of oral cannabis consumption during pregnancy on maternal spiral artery remodelling, fetal growth and offspring behaviour in mice

1
1. scibot 07 Feb 2025
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.ebiom.2025.105572
  
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sciencedirect.com/science/article/pii/S2352396425000167
Dec 2024
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

1
1. scibot 14 Dec 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.ccell.2024.11.008
  
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sciencedirect.com/science/article/pii/S1535610824004434
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

1
1. scibot 12 Dec 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2024.115039
  
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sciencedirect.com/science/article/pii/S2211124724013901
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

1
1. scibot 06 Dec 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
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IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells

1
1. scibot 02 Dec 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2024.114948
  
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sciencedirect.com/science/article/pii/S2211124724012993
Nov 2024
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HDAC1 fine-tunes Th17 polarization in vivo to restrain tissue damage in fungal infections

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1. scibot 28 Nov 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2024.114993
  
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sciencedirect.com/science/article/pii/S2211124724013445
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Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection

1
1. scibot 15 Nov 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2024.114951
  
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sciencedirect.com/science/article/pii/S2211124724013020
Oct 2024
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Stress triggers irritable bowel syndrome with diarrhea through a spermidine-mediated decline in type I interferon

1
1. scibot 04 Oct 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.cmet.2024.09.002
  
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sciencedirect.com/science/article/pii/S1550413124003668
Sep 2024
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Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth

1
1. scibot 25 Sep 2024
  
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  RRID:AB_315403
  
  DOI: 10.1016/j.celrep.2020.01.035
  
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sciencedirect.com/science/article/pii/S2211124720300504
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H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response

1
1. scibot 04 Sep 2024
  
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  AB_315404
  
  DOI: 10.1016/j.celrep.2024.114686
  
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sciencedirect.com/science/article/pii/S2211124724010374
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment

1
1. scibot 04 Sep 2024
  
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  AB_315404
  
  DOI: 10.1016/j.isci.2024.110810
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11404196/
Aug 2024
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Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females

1
1. scibot 22 Aug 2024
  
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  AB_315404
  
  DOI: 10.1016/j.cmet.2024.07.017
  
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sciencedirect.com/science/article/pii/S1550413124002882
Jul 2024
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MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells

1
1. scibot 31 Jul 2024
  
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  AB_315404
  
  DOI: 10.1016/j.celrep.2024.114565
  
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sciencedirect.com/science/article/pii/S2211124724008945
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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

1
1. scibot 12 Jul 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.cmet.2024.06.010
  
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sciencedirect.com/science/article/pii/S1550413124002353
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SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration

2
1. scibot 12 Jul 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2024.114458
  
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2. scibot 12 Jul 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.celrep.2024.114458
  
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sciencedirect.com/science/article/pii/S2211124724007873
www.cell.com www.cell.com

Mitochondrial DNA-boosted dendritic cell-based nanovaccination triggers antitumor immunity in lung and pancreatic cancers

1
1. scibot 12 Jul 2024
  
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  RRID:AB_315404
  
  DOI: 10.1016/j.xcrm.2024.101648
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00362-8
Jun 2024
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Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement

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Landscape of tumoral ecosystem for enhanced anti-PD-1 immunotherapy by gut Akkermansia muciniphila

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May 2024
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CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity

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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

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Gingival-derived mesenchymal stem cells alleviate allergic asthma inflammation via HGF in animal models

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52.53.155.43/77b0b81fcd376689bbdc4cf0ee4300be323e1a77/PIIS258900422401040X-html.html
Apr 2024
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Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis

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Feb 2024
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Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity

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Jan 2024
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Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms

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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent

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Nov 2023
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Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity

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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses

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Oct 2023
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Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

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The Transcription Factor IRF4 Determines the Anti-Tumor Immunity of CD8+ T cells

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A micro-electroporation/electrophoresis-based vaccine screening system reveals the impact of vaccination orders on cross-protective immunity

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Aug 2023
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Tumor-associated macrophages trigger MAIT cell dysfunction at the HCC invasive margin

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Endogenous CCL21-Ser deficiency reduces B16–F10 melanoma growth by enhanced antitumor immunity

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Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry

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Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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Jul 2023
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CCL21-Ser expression in melanoma cells recruits CCR7+ naïve T cells to tumor tissues and promotes tumor growth

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Jun 2023
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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system

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May 2023
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Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment

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Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis

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Apr 2023
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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

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T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

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Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir

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Spleen fibroblastic reticular cell-derived acetylcholine promotes lipid metabolism to drive autoreactive B cell responses

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Mar 2023
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Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING

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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

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TRIB2 safeguards naive T cell homeostasis during aging

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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions

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Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity

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Feb 2023
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The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection

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HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma

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  DOI: 10.1016/j.isci.2023.106143
  
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Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury

1
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  DOI: 10.1016/j.celrep.2023.112035
  
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Opioid-induced fragile-like regulatory T cells contribute to withdrawal

1
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  DOI: 10.1016/j.cell.2022.12.030
  
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Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages

1
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RAGE deficiency ameliorates autoimmune hepatitis involving inhibition of IL-6 production via suppressing protein Arid5a in mice

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  DOI: 10.1007/s10238-022-00960-8
  
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Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis

1
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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

1
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Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells

1
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Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

1
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

1
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Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity

1
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Phospholipid metabolites of the gut microbiota promote hypoxia-induced intestinal injury via CD1d-dependent γδ T cells

1
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  RRID:AB_315404
  
  DOI: 10.1080/19490976.2022.2096994
  
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Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

1
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B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation

1
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

1
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  DOI: 10.1016/j.cell.2022.04.019
  
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Circular RNA vaccines against SARS-CoV-2 and emerging variants

1
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  DOI: 10.1016/j.cell.2022.03.044
  
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Mar 2022
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Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response

1
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  DOI: 10.1158/2326-6066.CIR-20-0925
  
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Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination

1
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  DOI: 10.1016/j.celrep.2022.110388
  
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A Bivalent Nanoparticle Vaccine Exhibits Potent Cross-protection against the Variants of SARS-CoV-2

1
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  DOI: 10.1016/j.celrep.2021.110256
  
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Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models

1
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Detection of CD8+ T cell-mediated immune responses to bacterial infection in mice

1
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Vectored antibody gene delivery restores host B and T cell control of persistent viral infection

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The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1

1
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Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade

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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

1
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  DOI: 10.7554/eLife.67476
  
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Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity

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  DOI: 10.3389/fimmu.2021.726393
  
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Aug 2021
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Untitled document

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  DOI: 10.7554/eLife.44210
  
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Untitled document

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  DOI: 10.1016/j.celrep.2018.10.073
  
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Untitled document

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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

2
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  RRID:AB_315404
  
  DOI: 10.1016/j.chom.2019.03.003
  
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  DOI: 10.1016/j.chom.2019.03.003
  
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An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

1
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  DOI: 10.1016/j.immuni.2018.09.011
  
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NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines

1
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  DOI: 10.1016/j.cell.2018.10.028
  
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Jun 2021
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A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens

1
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  DOI: 10.1016/j.isci.2021.102699
  
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NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses

1
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The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

1
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  DOI: 10.1016/j.celrep.2021.109235
  
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Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome

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  DOI: 10.1016/j.celrep.2021.109201
  
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May 2021
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Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

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Fate mapping analysis reveals a novel murine dermal migratory Langerhans-like cell population

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Recombinant Orthopoxvirus Primes Colon Cancer for Checkpoint Inhibitor and Cross-Primes T Cells for Antitumor and Antiviral Immunity

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Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

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Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

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Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

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Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

1
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CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

1
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Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy

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Dynamic adoption of anergy by antigen-exhausted CD4+ T cells

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Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses

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Induction of Progenitor Exhausted Tissue-Resident Memory CD8+ T Cells Upon Salmonella Typhi Porins Adjuvant Immunization Correlates With Melanoma Control and Anti-PD-1 Immunotherapy Cooperation

1
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

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CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

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High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision

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FOXD3 Regulates VISTA Expression in Melanoma

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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

1
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Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium

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Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip

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Defects in Antiviral T Cell Responses Inflicted by Aging-Associated miR-181a Deficiency

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Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy

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Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection

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IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection

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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

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  DOI: 10.1016/j.cell.2019.07.044
  
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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

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Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

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Quantitative Difference in PLZF Protein Expression Determines iNKT Lineage Fate and Controls Innate CD8 T Cell Generation

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Untitled document

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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

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CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

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Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells

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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

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Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism

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Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

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KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

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Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.

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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

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