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Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.devcel.2025.10.017
  
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sciencedirect.com:5037/science/article/pii/S1534580725006914
Nov 2025
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UDP-GlcUA triggers PKR kinase activity to promote liquid-liquid phase separation of TOP2A and enhances radioimmunotherapy resistance

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.molcel.2025.10.011
  
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sciencedirect.com/science/article/pii/S1097276525008287
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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  DOI: 10.1016/j.immuni.2025.06.006
  
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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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Immune imprinting blunts omicron pathogenicity fluctuations and highlights the essential role of cellular immunity in SARS-CoV-2 infection

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1. scibot 05 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115784
  
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sciencedirect.com/science/article/pii/S2211124725005558
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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The role of Tim-3+T cell subsets in the peripheral blood of patients with COVID-19 and diabetes

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112339
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12053769/
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Glycosylation-driven programs coordinate immunoregulatory and pro-angiogenic functions of myeloid-derived suppressor cells

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.027
  
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sciencedirect.com/science/article/pii/S1074761325001906
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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.020
  
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sciencedirect.com/science/article/pii/S1074761325001839
Mar 2025
www.cell.com www.cell.com

Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

1
1. scibot 24 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102035
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00108-9
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AGO2 mediates immunotherapy failure via suppressing tumor IFN-gamma response-dependent CD8+ T cell immunity

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115445
  
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sciencedirect.com/science/article/pii/S2211124725002165
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Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

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1. scibot 04 Mar 2025
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2025.02.012
  
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sciencedirect.com/science/article/pii/S1074761325000792
Jan 2025
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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs

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1. scibot 03 Jan 2025
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2024.12.003
  
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sciencedirect.com/science/article/pii/S1074761324005673
Dec 2024
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Mannose metabolism reshapes T cell differentiation to enhance anti-tumor immunity

1
1. scibot 06 Dec 2024
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.ccell.2024.11.003
  
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sciencedirect.com/science/article/pii/S1535610824004380
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Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells

1
1. scibot 02 Dec 2024
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.celrep.2024.115023
  
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sciencedirect.com/science/article/pii/S2211124724013743
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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity

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1. scibot 02 Dec 2024
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.ccell.2024.10.014
  
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sciencedirect.com/science/article/pii/S1535610824004021
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

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1. scibot 04 Oct 2024
  
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  RRID:AB_315427
  
  DOI: 10.1158/0008-5472.CAN-23-3257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443216/
May 2024
www.cell.com www.cell.com

The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.026
  
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cell.com/immunity/fulltext/S1074-7613(24)00231-0
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

1
1. scibot 14 May 2024
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.cell.2024.04.023
  
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sciencedirect.com/science/article/pii/S0092867424004483
Apr 2024
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Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

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1. scibot 02 Apr 2024
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.cell.2024.03.011
  
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sciencedirect.com/science/article/pii/S0092867424003039
Feb 2024
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Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity

2
1. scibot 21 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113796
  
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  DOI: 10.1016/j.celrep.2024.113796
  
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sciencedirect.com/science/article/pii/S2211124724001244
52.53.155.43 52.53.155.43

Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

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1. scibot 14 Feb 2024
  
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  AB_315427
  
  DOI: 10.1101/2022.09.03.506476
  
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52.53.155.43/ed5ac003e0303d13fddfbb7e3e68d91d0475a989/2022.09.03.506476v1.full-html.html
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Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5

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1. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.cmet.2024.01.012
  
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sciencedirect.com/science/article/pii/S1550413124000123
Nov 2023
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Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.immuni.2023.10.010
  
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sciencedirect.com/science/article/abs/pii/S107476132300451X
Oct 2023
www.cell.com www.cell.com

The Transcription Factor IRF4 Determines the Anti-Tumor Immunity of CD8+ T cells

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.108087
  
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cell.com/iscience/abstract/S2589-0042(23)02164-8
Aug 2023
52.53.155.43 52.53.155.43

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

2
1. scibot 17 Aug 2023
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.celrep.2023.112944
  
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2. scibot 11 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112944
  
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52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD

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1. scibot 08 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112753
  
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sciencedirect.com/science/article/pii/S2211124723007647
Jun 2023
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DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.cell.2023.05.028
  
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sciencedirect.com/science/article/pii/S0092867423005809
May 2023
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Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment

1
1. scibot 13 May 2023
  
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  DOI: 10.1016/j.cmet.2023.04.017
  
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sciencedirect.com/science/article/pii/S1550413123001717
Jan 2023
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CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy

1
1. scibot 04 Jan 2023
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.xcrm.2022.100878
  
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sciencedirect.com/science/article/pii/S2666379122004426
Sep 2022
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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

1
1. scibot 24 Sep 2022
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.ccell.2022.08.016
  
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sciencedirect.com/science/article/pii/S1535610822003804
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Quantitative Increase in T Regulatory Cells Enhances Bone Remodeling in Osteogenesis Imperfecta

1
1. scibot 27 Aug 2022
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.isci.2022.104818
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9400089/
May 2022
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer

1
1. scibot 27 May 2022
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.ccell.2022.05.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9197962/
Mar 2022
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Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection

1
1. scibot 02 Mar 2022
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2022.01.018
  
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sciencedirect.com/science/article/pii/S1074761322000474
Feb 2022
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Balanced T and B cell responses are required for immune protection against Powassan virus in virus-like particle vaccination

1
1. scibot 16 Feb 2022
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.celrep.2022.110388
  
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sciencedirect.com/science/article/pii/S2211124722001097
Dec 2021
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Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models

1
1. scibot 22 Dec 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.ebiom.2021.103762
  
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sciencedirect.com/science/article/pii/S2352396421005569
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Detection of CD8+ T cell-mediated immune responses to bacterial infection in mice

1
1. scibot 15 Dec 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.xpro.2021.101022
  
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sciencedirect.com/science/article/pii/S2666166721007280
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation

1
1. scibot 08 Dec 2021
  
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  RRID:AB_315427
  
  DOI: 10.7554/eLife.70978
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8639145/
Sep 2021
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Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

1
1. scibot 18 Sep 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.cell.2021.08.020
  
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Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

1
1. scibot 17 Sep 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2021.08.026
  
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sciencedirect.com/science/article/pii/S1074761321003605
Aug 2021
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Untitled document

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1. scibot 04 Aug 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2018.10.008
  
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sciencedirect.com/science/article/pii/S1074761318304497
Jul 2021
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Macrophage and neutrophil death programs differentially confer resistance to tuberculosis

1
1. scibot 13 Jul 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2021.06.009
  
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sciencedirect.com/science/article/pii/S1074761321002533
May 2021
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Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection

1
1. scibot 26 May 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.celrep.2021.109160
  
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sciencedirect.com/science/article/pii/S2211124721005027
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Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation

1
1. scibot 01 May 2021
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2021.04.007
  
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sciencedirect.com/science/article/pii/S1074761321001692
Apr 2021
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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer

1
1. scibot 06 Apr 2021
  
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  PE conjugated anti-TNF
  
  DOI: 10.1016/j.immuni.2021.02.020
  
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sciencedirect.com/science/article/pii/S1074761321000868
Dec 2020
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SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity

1
1. scibot 07 Dec 2020
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.celrep.2020.108468
  
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sciencedirect.com/science/article/pii/S2211124720314571
Sep 2020
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C9orf72 in myeloid cells suppresses STING-induced inflammation

1
1. scibot 03 Sep 2020
  
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  anti-tumour necrosis factor
  
  DOI: 10.1038/s41586-020-2625-x
  
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nature.com/articles/s41586-020-2625-x
Jan 2020
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CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2019.10.009
  
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sciencedirect.com/science/article/pii/S1074761319304534
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Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

1
1. scibot 13 Jan 2020
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.cell.2019.08.012
  
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TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.celrep.2019.11.102
  
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sciencedirect.com/science/article/pii/S221112471931602X
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2018.12.024
  
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Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_315427
  
  DOI: 10.1016/j.chom.2019.02.014
  
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sciencedirect.com/science/article/pii/S1931312819301106
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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

1
1. scibot 12 Jan 2020
  
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  RRID:AB_315427
  
  DOI: 10.1016/j.immuni.2019.03.005
  
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sciencedirect.com/science/article/pii/S1074761319300950
Nov 2018
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Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1550413118304431
europepmc.org europepmc.org

Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?

1
1. scibot 05 Nov 2018
  
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  RRID:AB_315427
  
  Curator: @evieth
  
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europepmc.org/articles/PMC5985376/
www.frontiersin.org www.frontiersin.org

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_315427
  
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frontiersin.org/article/10.3389/fimmu.2018.01178/full
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TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer

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sciencedirect.com/science/article/pii/S1535610817305238