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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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    sciencedirect.com/science/article/pii/S1535610824002708
  3. Jul 2024
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    Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer
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  5. Feb 2024
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    Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Radix Paeoniae Rubra Against Glioma
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  7. Dec 2023
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    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    sciencedirect.com/science/article/pii/S2589004223026731
  9. Oct 2023
  10. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Bilirubin impacts microglial autophagy via the Akt–mTOR signaling pathway
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  11. Aug 2023
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    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    sciencedirect.com/science/article/pii/S1097276523005580
  13. Jul 2023
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    GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells
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  15. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
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      DOI: 10.1126/sciadv.adg9593

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  17. Jun 2023
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    Identification and validation of Rab11a in Rat orofacial inflammatory pain model induced by CFA
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    sciencedirect.com/science/article/pii/S0197018623000785
  19. Apr 2023
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    Design of Diversified Chimeric Antigen Receptors Through Rational Module Recombination
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  21. Feb 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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  23. Jan 2023
  24. journals.lww.com journals.lww.com
    PTEN inhibitor bisperoxovanadium protects against... : Neural Regeneration Research
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  25. Dec 2022
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    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    sciencedirect.com/science/article/pii/S2211124722016424
  27. Sep 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
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  29. Mar 2022
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    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model
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      DOI: 10.3389/fnins.2021.804722

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  32. Feb 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions
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  34. Dec 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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      DOI: 10.3389/fphys.2021.779547

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  36. May 2021
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    The E3 ligase TRAF4 Promotes IGF Signaling by Mediating Atypical Ubiquitination of IRS-1
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      anti–PI3 Kinase p85

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    sciencedirect.com/science/article/pii/S0021925821005287
  38. Feb 2021
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle
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  41. Sep 2020
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    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
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    sciencedirect.com/science/article/pii/S0006295220301775
  43. cancerres.aacrjournals.org cancerres.aacrjournals.org
    CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
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      DOI: 10.1158/0008-5472.CAN-19-1161

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    Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy
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  45. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  46. www.mdpi.com www.mdpi.com
    Looking for a Better Characterization of Triple-Negative Breast Cancer by Means of Circulating Tumor Cells
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      anti-PI3K

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  47. stke.sciencemag.org stke.sciencemag.org
    Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis
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      PIK3R1 (p85)

      DOI: 10.1126/scisignal.aax2364

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  48. Jan 2020
  49. www.sciencedirect.com www.sciencedirect.com
    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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      DOI: 10.1016/j.immuni.2019.11.003

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  50. academic.oup.com academic.oup.com
    Perioperative infusion of glucagon like peptide-1 prevents insulin resistance after surgical trauma in female pigs
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      DOI: 10.1210/en.2019-00374

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    academic.oup.com/endo/article/160/12/2892/5581188
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA MEG3 contributes to adenosine‐induced cytotoxicity in hepatoma HepG2 cells by downregulated ILF3 and autophagy inhibition via regulation PI3K‐AKT‐mTOR and beclin‐1 signaling pathway
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  52. link.springer.com link.springer.com
    Untitled document
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      DOI: 10.1007/s12640-018-9991-2

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    link.springer.com/article/10.1007/s12640-018-9991-2
  53. Nov 2018
  54. content.iospress.com content.iospress.com
    NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad180284
  55. www.sciencedirect.com www.sciencedirect.com
    Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells
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    sciencedirect.com/science/article/pii/S2211124718309641
  56. Nov 2017
  57. academic.oup.com academic.oup.com
    Aldose Reductase Mediates NLRP3 Inflammasome–Initiated Innate Immune Response in Hyperglycemia-Induced Thp1 Monocytes and Male Mice
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    academic.oup.com/endo/article/158/10/3661/4049499/Aldose-Reductase-Mediates-NLRP3-Inflammasome