23 Matching Annotations
  1. Apr 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Rational discovery of therapeutic PAK1 allosteric activators
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    sciencedirect.com/science/article/pii/S0092867426002758
  3. Aug 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Crystal structures of PAK2 reveal new insights into its autoinhibitory mechanism
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    sciencedirect.com/science/article/pii/S0969212625002564
  5. May 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Focal Adhesion Kinase Orchestrates GLUT4 Translocation and Glucose Uptake via Cytoskeletal Turnover in Primary Adipocytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12093284/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
  8. Mar 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
  10. Dec 2024
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits
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    pmc.ncbi.nlm.nih.gov/articles/PMC11624886/
  12. Aug 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  14. Jan 2024
  15. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    science.org/doi/10.1126/scisignal.adg5289
  16. Jan 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC9715480/
  18. Apr 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Lockdown, a selective small-molecule inhibitor of the integrin phosphatase PPM1F, blocks cancer cell invasion
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    sciencedirect.com/science/article/pii/S2451945622001283
  20. www.sciencedirect.com www.sciencedirect.com
    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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    sciencedirect.com/science/article/pii/S1097276522002647
  21. Mar 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC8870177/
  23. Aug 2021
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The small GTPase Rac1 contributes to extinction of aversive memories of drug withdrawal by facilitating GABA<sub>A</sub> receptor endocytosis in the vmPFC
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    ncbi.nlm.nih.gov/pmc/articles/PMC6705728/
  25. Jun 2021
  26. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 infects human pancreatic β-cells and elicits β-cell impairment
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    sciencedirect.com/science/article/pii/S1550413121002308
  27. May 2021
  28. www.sciencedirect.com www.sciencedirect.com
    Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects
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    sciencedirect.com/science/article/pii/S1534580720303981
  29. Apr 2021
  30. link.springer.com link.springer.com
    Semaphorin3F Drives Dendritic Spine Pruning Through Rho-GTPase Signaling
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    link.springer.com/article/10.1007/s12035-021-02373-2
  31. Mar 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK
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    sciencedirect.com/science/article/pii/S2211124721001145
  33. Feb 2021
  34. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
    1
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280294
  35. Jan 2020
  36. elifesciences.org elifesciences.org
    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
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    elifesciences.org/articles/49175
  37. Nov 2017
  38. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/37/30/7096
  39. www.sciencedirect.com www.sciencedirect.com
    An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
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    sciencedirect.com/science/article/pii/S1934590917300942