31 Matching Annotations
  1. Apr 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Rational discovery of therapeutic PAK1 allosteric activators
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867426002758
  3. Jan 2026
  4. www.science.org www.science.org
    Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.adu8292
  5. Jun 2025
  6. www.sciencedirect.com www.sciencedirect.com
    Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2405471225001541
  7. Mar 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
  9. Feb 2025
  10. www.sciencedirect.com www.sciencedirect.com
    N-cadherin-triggered myosin II inactivation provides tumor cells with a mechanical cell competition advantage and chemotherapy resistance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580725000619
  11. Dec 2024
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modelling quiescence exit of neural stem cells reveals a FOXG1-FOXO6 axis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11625887/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11624886/
  14. Sep 2024
  15. www.sciencedirect.com www.sciencedirect.com
    IGFBP7 is upregulated in islets from T2D donors and reduces insulin secretion
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004224019928
  16. Aug 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  18. Jul 2024
  19. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html
  20. Feb 2024
  21. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/scisignal.adg5289
  22. Jan 2024
  23. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/scisignal.adg5289
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723014262
  26. Aug 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10387573/
  29. Jun 2022
  30. www.nature.com www.nature.com
    Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41380-022-01643-2
  31. Apr 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522002647
  33. www.sciencedirect.com www.sciencedirect.com
    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472200393X
  34. Sep 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721011360
  36. journals.plos.org journals.plos.org
    A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    journals.plos.org/plospathogens/article
  37. Jul 2021
  38. mbio.asm.org mbio.asm.org
    Pathogenic Escherichia coli Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mbio.asm.org/content/10/4/e01876-19
  39. Apr 2021
  40. www.jneurosci.org www.jneurosci.org
    PAK1 positively regulates oligodendrocyte morphology and myelination.
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jneurosci.org/content/41/9/1864
  41. Mar 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Endothelin-1 drives invadopodia and interaction with mesothelial cells through ILK
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721001145
  43. Dec 2020
  44. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Insulin‐stimulated glucose uptake partly relies on p21‐activated kinase 2 (PAK2), but not PAK1, in mouse skeletal muscle
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    physoc.onlinelibrary.wiley.com/doi/10.1113/JP280294
  45. Sep 2020
  46. www.sciencedirect.com www.sciencedirect.com
    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720307245
  47. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14460
  48. Jan 2020
  49. elifesciences.org elifesciences.org
    Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/49175
  50. www.sciencedirect.com www.sciencedirect.com
    PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719314871
  51. www.jneurosci.org www.jneurosci.org
    Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jneurosci.org/content/39/25/4959
  52. Nov 2018
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
  54. 52.53.155.43 52.53.155.43
    A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/0bf5a35474616f8cd124d354ba59ef8784f885ac/A_dual_role_for_Integrin_64_in_modulat-html.html