33 Matching Annotations
  1. Jun 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ROUX-en-Y gastric bypass surgery improves metabolic syndrome–related erectile dysfunction in mice via the IRS-1/PI3K/AKT/eNOS pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11134102/
  3. May 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Sex-and depot-specific differences in cellular insulin responsiveness during adipose expansion
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    sciencedirect.com/science/article/pii/S0024320525003789
  5. Jan 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant
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    pmc.ncbi.nlm.nih.gov/articles/PMC11750134/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Central Downregulation of S-Resistin Alleviates Inflammation in EWAT and Liver and Prevents Adipocyte Hypertrophy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11725382/
  8. Dec 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Proteolethargy is a pathogenic mechanism in chronic disease
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    sciencedirect.com/science/article/pii/S0092867424012741
  10. Apr 2024
  11. dx.doi.org dx.doi.org
    β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo
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    dx.doi.org/10.1210/endocr/bqae044
  12. Feb 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
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    sciencedirect.com/science/article/pii/S2589004224003420
  14. Nov 2023
  15. www.sciencedirect.com www.sciencedirect.com
    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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    sciencedirect.com/science/article/pii/S2451945623003847
  16. Sep 2023
  17. www.sciencedirect.com www.sciencedirect.com
    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
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    sciencedirect.com/science/article/pii/S0925443923002624
  18. Aug 2023
  19. www.sciencedirect.com www.sciencedirect.com
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    sciencedirect.com/science/article/pii/S1097276523005580
  20. Jul 2023
  21. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
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    sciencedirect.com/science/article/pii/S2211124723008793
  22. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
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    52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
  23. Apr 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10040733/
  25. Jan 2023
  26. academic.oup.com academic.oup.com
    Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice
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    academic.oup.com/endo/article/164/3/bqac214/6969391
  27. Nov 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9674348/
  29. Sep 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
  31. Dec 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  33. Aug 2021
  34. www.sciencedirect.com www.sciencedirect.com
    GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
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    sciencedirect.com/science/article/pii/S2211124721009293
  35. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14553
  36. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14553
  37. Jul 2021
  38. academic.oup.com academic.oup.com
    Untitled document
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    academic.oup.com/endo/article/159/9/3365/5060456
  39. Apr 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
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    sciencedirect.com/science/article/pii/S0092867421003627
  41. Feb 2021
  42. www.cell.com www.cell.com
    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
  43. Dec 2020
  44. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14672
  45. Sep 2020
  46. www.sciencedirect.com www.sciencedirect.com
    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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    sciencedirect.com/science/article/pii/S1550413120301224
  47. www.sciencedirect.com www.sciencedirect.com
    Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling
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    sciencedirect.com/science/article/pii/S221112472030992X
  48. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15195
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC5966754/
  50. Jan 2020
  51. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14802
  52. Nov 2018
  53. academic.oup.com academic.oup.com
    Combined Hyperglycemia- and Hyperinsulinemia-Induced Insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ
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    academic.oup.com/endo/article/159/4/1658/4822182
  54. Nov 2017
  55. www.sciencedirect.com www.sciencedirect.com
    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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    sciencedirect.com/science/article/pii/S1097276517304914
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice
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    onlinelibrary.wiley.com/doi/10.1002/jcb.26046/full
  57. academic.oup.com academic.oup.com
    Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms
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    academic.oup.com/endo/article/158/3/531/3053378/Low-Dose-Dihydrotestosterone-Drives-Metabolic