Hypothesis

37 Matching Annotations

Apr 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226010953-main-html.html

1
1. scibot 15 Apr 2026
  
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  AB_330333
  
  DOI: 10.1016/j.isci.2026.115720
  
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54.241.53.176/0d86f849e6041714949b051c885a9817a0a7d3a7/1-s2.0-S2589004226010953-main-html.html
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Gut glucose assimilation governs glucose homeostasis through reciprocal interaction between glucose and amino acid transporter

1
1. scibot 26 Mar 2026
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.celrep.2026.117104
  
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sciencedirect.com/science/article/pii/S2211124726001828
Feb 2026
www.sciencedirect.com www.sciencedirect.com

MEDAG functions as an A-kinase-anchoring protein in adipocytes

1
1. scibot 26 Feb 2026
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.molcel.2026.02.001
  
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sciencedirect.com/science/article/pii/S1097276526000961
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ducts

1
1. scibot 18 Dec 2025
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.celrep.2025.116703
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12990061/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ROUX-en-Y gastric bypass surgery improves metabolic syndrome–related erectile dysfunction in mice via the IRS-1/PI3K/AKT/eNOS pathway

1
1. scibot 11 Jun 2025
  
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  RRID:AB_330333
  
  DOI: 10.1093/sexmed/qfae029
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11134102/
May 2025
www.sciencedirect.com www.sciencedirect.com

Sex-and depot-specific differences in cellular insulin responsiveness during adipose expansion

1
1. scibot 22 May 2025
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.lfs.2025.123743
  
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sciencedirect.com/science/article/pii/S0024320525003789
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant

1
1. scibot 23 Jan 2025
  
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  RRID:AB_330333
  
  DOI: 10.7554/eLife.94420
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750134/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Central Downregulation of S-Resistin Alleviates Inflammation in EWAT and Liver and Prevents Adipocyte Hypertrophy

1
1. scibot 14 Jan 2025
  
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  RRID:AB_330333
  
  DOI: 10.1210/jendso/bvae224
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11725382/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Proteolethargy is a pathogenic mechanism in chronic disease

1
1. scibot 02 Dec 2024
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.cell.2024.10.051
  
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sciencedirect.com/science/article/pii/S0092867424012741
Apr 2024
dx.doi.org dx.doi.org

β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo

1
1. scibot 10 Apr 2024
  
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  AB_330333
  
  DOI: 10.1210/endocr/bqae044
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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dx.doi.org/10.1210/endocr/bqae044
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity

1
1. scibot 27 Feb 2024
  
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  Cell Signaling Technology#2382
  
  DOI: 10.1016/j.isci.2024.109121
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S2589004224003420
Nov 2023
www.sciencedirect.com www.sciencedirect.com

PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer

1
1. scibot 28 Nov 2023
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.chembiol.2023.10.023
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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sciencedirect.com/science/article/pii/S2451945623003847
Sep 2023
www.sciencedirect.com www.sciencedirect.com

TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice

1
1. scibot 30 Sep 2023
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.bbadis.2023.166896
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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sciencedirect.com/science/article/pii/S0925443923002624
Aug 2023
www.sciencedirect.com www.sciencedirect.com

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

1
1. scibot 11 Aug 2023
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.molcel.2023.07.015
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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sciencedirect.com/science/article/pii/S1097276523005580
Jul 2023
www.sciencedirect.com www.sciencedirect.com

mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

1
1. scibot 27 Jul 2023
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.celrep.2023.112868
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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sciencedirect.com/science/article/pii/S2211124723008793
52.53.155.43 52.53.155.43

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

1
1. scibot 18 Jul 2023
  
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  RRID:AB_330333
  
  DOI: 10.1101/2023.05.18.541123
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease

1
1. scibot 05 Apr 2023
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.isci.2023.106355
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10040733/
Jan 2023
academic.oup.com academic.oup.com

Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice

1
1. scibot 21 Jan 2023
  
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  AB_330333
  
  DOI: 10.1210/endocr/bqac214
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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academic.oup.com/endo/article/164/3/bqac214/6969391
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation

1
1. scibot 22 Nov 2022
  
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  RRID:AB_330333
  
  DOI: 10.7554/eLife.81559
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9674348/
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation

1
1. scibot 30 Sep 2022
  
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  RRID:AB_330333
  
  DOI: 10.3389/fimmu.2022.931087
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation

1
1. scibot 17 Dec 2021
  
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  AB_330333
  
  DOI: 10.3389/fphys.2021.779547
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

1
1. scibot 15 Aug 2021
  
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  AB_330333
  
  DOI: 10.1016/j.celrep.2021.109501
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124721009293
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Untitled document

1
1. scibot 12 Aug 2021
  
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  RRID:AB_330333
  
  DOI: 10.1111/bph.14553
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14553
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Untitled document

1
1. scibot 03 Aug 2021
  
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  RRID:AB_330333
  
  DOI: 10.1111/bph.14553
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @scibot
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14553
Jul 2021
academic.oup.com academic.oup.com

Untitled document

1
1. scibot 30 Jul 2021
  
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  RRID:AB_330333
  
  DOI: 10.1210/en.2018-00531
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_330333
  
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  RRID:AB_330333 RRIDCUR:Validated
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academic.oup.com/endo/article/159/9/3365/5060456
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

1
1. scibot 13 Apr 2021
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.cell.2021.03.031
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
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  RRID:AB_330333 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867421003627
Feb 2021
www.cell.com www.cell.com

Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53

1
1. scibot 25 Feb 2021
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.molcel.2020.12.008
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_330333
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cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
Dec 2020
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model

1
1. scibot 30 Dec 2020
  
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  RRID:AB_330333
  
  DOI: 10.14814/phy2.14672
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_330333
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physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14672
Sep 2020
www.sciencedirect.com www.sciencedirect.com

TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation

1
1. scibot 23 Sep 2020
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.cmet.2020.03.007
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_330333
  
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  RRID:AB_330333 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413120301224
www.sciencedirect.com www.sciencedirect.com

Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling

1
1. scibot 16 Sep 2020
  
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  RRID:AB_330333
  
  DOI: 10.1016/j.celrep.2020.108007
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_330333
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sciencedirect.com/science/article/pii/S221112472030992X
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes

1
1. scibot 12 Sep 2020
  
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  RRID:AB_330333
  
  DOI: 10.1111/bph.15195
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_330333
  
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  RRID:AB_330333 RRIDCUR:Validated
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15195
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice

1
1. scibot 09 Sep 2020
  
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  AB_330333
  
  DOI: 10.1152/ajpendo.00195.2017
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_330333
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ncbi.nlm.nih.gov/pmc/articles/PMC5966754/
Jan 2020
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 13 Jan 2020
  
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  RRID:AB_330333
  
  DOI: 10.1111/bph.14802
  
  Resource: (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_330333
  
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  RRID:AB_330333 RRIDCUR:Validated
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14802
Nov 2018
academic.oup.com academic.oup.com

Combined Hyperglycemia- and Hyperinsulinemia-Induced Insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ

1
1. scibot 05 Nov 2018
  
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  AB_330333
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  SciCrunch record: RRID:AB_330333
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_330333 RRIDCUR:Validated
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academic.oup.com/endo/article/159/4/1658/4822182
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition

1
1. scibot 08 Nov 2017
  
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  AB_330333
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  SciCrunch record: RRID:AB_330333
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_330333 RRIDCUR:Validated
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RRID:AB_330333

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sciencedirect.com/science/article/pii/S1097276517304914
onlinelibrary.wiley.com onlinelibrary.wiley.com

Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice

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1. scibot 08 Nov 2017
  
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  RRID:AB_330333
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.26046/full
academic.oup.com academic.oup.com

Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms

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1. scibot 08 Nov 2017
  
  in Public
  
  AB_330333
  
  Curator: @bandrow
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2382, RRID:AB_330333)
  
  SciCrunch record: RRID:AB_330333
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_330333
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RRID:AB_330333

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academic.oup.com/endo/article/158/3/531/3053378/Low-Dose-Dihydrotestosterone-Drives-Metabolic