29 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Proteolethargy is a pathogenic mechanism in chronic disease
    1
    1. scibot 02 Dec 2024
      RRID:AB_330333

      DOI: 10.1016/j.cell.2024.10.051

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    sciencedirect.com/science/article/pii/S0092867424012741
  3. Apr 2024
  4. dx.doi.org dx.doi.org
    β-cell insulin resistance plays a causal role in fat-induced β-cell dysfunction in vitro and in vivo
    1
    1. scibot 10 Apr 2024
      AB_330333

      DOI: 10.1210/endocr/bqae044

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    dx.doi.org/10.1210/endocr/bqae044
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
    1
    1. scibot 27 Feb 2024
      Cell Signaling Technology#2382

      DOI: 10.1016/j.isci.2024.109121

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    sciencedirect.com/science/article/pii/S2589004224003420
  7. Nov 2023
  8. www.sciencedirect.com www.sciencedirect.com
    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.chembiol.2023.10.023

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    sciencedirect.com/science/article/pii/S2451945623003847
  9. Sep 2023
  10. www.sciencedirect.com www.sciencedirect.com
    TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice
    1
    1. scibot 30 Sep 2023
      RRID:AB_330333

      DOI: 10.1016/j.bbadis.2023.166896

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    sciencedirect.com/science/article/pii/S0925443923002624
  11. Aug 2023
  12. www.sciencedirect.com www.sciencedirect.com
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    1
    1. scibot 11 Aug 2023
      RRID:AB_330333

      DOI: 10.1016/j.molcel.2023.07.015

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    sciencedirect.com/science/article/pii/S1097276523005580
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
    1
    1. scibot 27 Jul 2023
      RRID:AB_330333

      DOI: 10.1016/j.celrep.2023.112868

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    sciencedirect.com/science/article/pii/S2211124723008793
  15. 52.53.155.43 52.53.155.43
    PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate
    1
    1. scibot 18 Jul 2023
      RRID:AB_330333

      DOI: 10.1101/2023.05.18.541123

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    52.53.155.43/47cafcf0b0c101b9655865f446b83a64cc86d1a1/2023.05.18.541123v1.full-html.html
  16. Apr 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
    1
    1. scibot 05 Apr 2023
      RRID:AB_330333

      DOI: 10.1016/j.isci.2023.106355

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    ncbi.nlm.nih.gov/pmc/articles/PMC10040733/
  18. Jan 2023
  19. academic.oup.com academic.oup.com
    Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice
    1
    1. scibot 21 Jan 2023
      AB_330333

      DOI: 10.1210/endocr/bqac214

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    academic.oup.com/endo/article/164/3/bqac214/6969391
  20. Nov 2022
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation
    1
    1. scibot 22 Nov 2022
      RRID:AB_330333

      DOI: 10.7554/eLife.81559

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    ncbi.nlm.nih.gov/pmc/articles/PMC9674348/
  22. Sep 2022
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
    1
    1. scibot 30 Sep 2022
      RRID:AB_330333

      DOI: 10.3389/fimmu.2022.931087

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    ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
  24. Dec 2021
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
    1
    1. scibot 17 Dec 2021
      AB_330333

      DOI: 10.3389/fphys.2021.779547

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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  26. Aug 2021
  27. www.sciencedirect.com www.sciencedirect.com
    GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
    1
    1. scibot 15 Aug 2021
      AB_330333

      DOI: 10.1016/j.celrep.2021.109501

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    sciencedirect.com/science/article/pii/S2211124721009293
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 12 Aug 2021
      RRID:AB_330333

      DOI: 10.1111/bph.14553

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14553
  29. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 03 Aug 2021
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      DOI: 10.1111/bph.14553

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14553
  30. Jul 2021
  31. academic.oup.com academic.oup.com
    Untitled document
    1
    1. scibot 30 Jul 2021
      RRID:AB_330333

      DOI: 10.1210/en.2018-00531

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    academic.oup.com/endo/article/159/9/3365/5060456
  32. Apr 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
    1
    1. scibot 13 Apr 2021
      RRID:AB_330333

      DOI: 10.1016/j.cell.2021.03.031

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    sciencedirect.com/science/article/pii/S0092867421003627
  34. Feb 2021
  35. www.cell.com www.cell.com
    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
    1
    1. scibot 25 Feb 2021
      RRID:AB_330333

      DOI: 10.1016/j.molcel.2020.12.008

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
  36. Dec 2020
  37. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
    1
    1. scibot 30 Dec 2020
      RRID:AB_330333

      DOI: 10.14814/phy2.14672

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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14672
  38. Sep 2020
  39. www.sciencedirect.com www.sciencedirect.com
    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
    1
    1. scibot 23 Sep 2020
      RRID:AB_330333

      DOI: 10.1016/j.cmet.2020.03.007

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    sciencedirect.com/science/article/pii/S1550413120301224
  40. www.sciencedirect.com www.sciencedirect.com
    Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling
    1
    1. scibot 16 Sep 2020
      RRID:AB_330333

      DOI: 10.1016/j.celrep.2020.108007

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    sciencedirect.com/science/article/pii/S221112472030992X
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes
    1
    1. scibot 12 Sep 2020
      RRID:AB_330333

      DOI: 10.1111/bph.15195

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15195
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Physiology: Insulin signaling displayed a differential tissue-specific response to low-dose dihydrotestosterone in female mice
    1
    1. scibot 09 Sep 2020
      AB_330333

      DOI: 10.1152/ajpendo.00195.2017

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    ncbi.nlm.nih.gov/pmc/articles/PMC5966754/
  43. Jan 2020
  44. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Jan 2020
      RRID:AB_330333

      DOI: 10.1111/bph.14802

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14802
  45. Nov 2018
  46. academic.oup.com academic.oup.com
    Combined Hyperglycemia- and Hyperinsulinemia-Induced Insulin Resistance in Adipocytes Is Associated With Dual Signaling Defects Mediated by PKC-ζ
    1
    1. scibot 05 Nov 2018
      AB_330333

      Curator: @evieth

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    academic.oup.com/endo/article/159/4/1658/4822182
  47. Nov 2017
  48. www.sciencedirect.com www.sciencedirect.com
    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
    1
    1. scibot 08 Nov 2017
      AB_330333

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1097276517304914
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice
    1
    1. scibot 08 Nov 2017
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    onlinelibrary.wiley.com/doi/10.1002/jcb.26046/full
  50. academic.oup.com academic.oup.com
    Low-Dose Dihydrotestosterone Drives Metabolic Dysfunction via Cytosolic and Nuclear Hepatic Androgen Receptor Mechanisms
    1
    1. scibot 08 Nov 2017
      AB_330333

      Curator: @bandrow

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    academic.oup.com/endo/article/158/3/531/3053378/Low-Dose-Dihydrotestosterone-Drives-Metabolic