Hypothesis

49 Matching Annotations

Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225016840-main-html.html

1
1. scibot 26 Aug 2025
  
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  AB_330403
  
  DOI: 10.1016/j.isci.2025.113423
  
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52.53.155.43/23fa3039143e04e3669aa6d24e522324d4b71ce2/1-s2.0-S2589004225016840-main-html.html
May 2025
www.sciencedirect.com www.sciencedirect.com

A Novel Compound DBZ Alleviates Chronic Inflammatory Pain and Anxiety-Like Behaviors by Targeting the JAK2-STAT3 Signaling Pathway

1
1. scibot 18 May 2025
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.jbc.2025.110223
  
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sciencedirect.com/science/article/pii/S0021925825020733
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Synergistic role of gut-microbial L-ornithine in enhancing ustekinumab efficacy for Crohn’s disease

1
1. scibot 20 Feb 2025
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.cmet.2025.01.007
  
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sciencedirect.com/science/article/pii/S1550413125000075
aacrjournals.org aacrjournals.org

TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma

1
1. scibot 13 Feb 2025
  
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  AB_330403
  
  DOI: 10.1158/0008-5472.CAN-22-3009
  
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aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
Dec 2024
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

Chronic sleep deprivation disturbs energy balance modulated by suprachiasmatic nucleus efferents in mice

1
1. scibot 27 Dec 2024
  
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  RRID:AB_330403
  
  DOI: 10.1186/s12915-024-02097-4
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-02097-4
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Deciphering the composition and key driver genes of breast invasive micropapillary carcinoma by multi-omics analysis

1
1. scibot 14 Nov 2024
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.isci.2024.111178
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11549989/
Aug 2024
jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com

Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells

1
1. scibot 02 Aug 2024
  
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  3771
  
  DOI: 10.1186/s12929-021-00769-9
  
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  RRID:AB_330403 RRIDCUR:Missing
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jbiomedsci.biomedcentral.com/articles/10.1186/s12929-021-00769-9
www.mdpi.com www.mdpi.com

A Novel Monoclonal Antibody Targeting Cancer-Specific Plectin Has Potent Antitumor Activity in Ovarian Cancer

1
1. scibot 02 Aug 2024
  
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  3771
  
  DOI: 10.3390/cells10092218
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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mdpi.com/2073-4409/10/9/2218/htm
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Influenza A virus infection activates STAT3 to enhance SREBP2 expression, cholesterol biosynthesis, and virus replication

1
1. scibot 19 Jul 2024
  
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  AB_330403
  
  DOI: 10.1016/j.isci.2024.110424
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11301072/
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ruxolitinib improves the inflammatory microenvironment, restores glutamate homeostasis, and promotes functional recovery after spinal cord injury

1
1. scibot 15 May 2024
  
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  RRID:AB_330403
  
  DOI: 10.4103/NRR.NRR-D-23-01863
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11090442/
www.sciencedirect.com www.sciencedirect.com

Active substances and molecular mechanisms of Astragali Radix and Angelicae Sinensis Radix against idiopathic pulmonary fibrosis effects by network pharmacology and in vitro experiments

1
1. scibot 14 May 2024
  
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  3771S
  
  DOI: 10.1016/j.cjac.2024.100397
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S1872204024000422
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 02 May 2024
  
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  RRID:AB_330403
  
  DOI: 10.1111/bph.16393
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16393
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

1
1. scibot 02 Apr 2024
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.cell.2024.03.011
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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sciencedirect.com/science/article/pii/S0092867424003039
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon

2
1. scibot 06 Mar 2024
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.devcel.2024.02.005
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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  RRID:AB_330403
2. scibot 06 Mar 2024
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.devcel.2024.02.005
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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  SciCrunch record: RRID:AB_330403
  
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sciencedirect.com/science/article/pii/S1534580724000765
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Tissue factor binds to and inhibits interferon-α receptor 1 signaling

1
1. scibot 23 Dec 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.immuni.2023.11.017
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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  SciCrunch record: RRID:AB_330403
  
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sciencedirect.com/science/article/pii/S1074761323004995
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis

1
1. scibot 30 Nov 2023
  
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  RRID:AB_330403
  
  DOI: 10.1038/s41467-023-43175-5
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10673935/
www.sciencedirect.com www.sciencedirect.com

Exosomes derived from platelet-rich plasma promote diabetic wound healing via the JAK2/STAT3 pathway

1
1. scibot 04 Nov 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.isci.2023.108236
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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sciencedirect.com/science/article/pii/S2589004223023131
Oct 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma

1
1. scibot 14 Oct 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.xcrm.2023.101214
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms

1
1. scibot 07 Sep 2023
  
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  RRID:AB_330403
  
  DOI: 10.1158/1078-0432.CCR-22-1763
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9992133/
Aug 2023
52.53.155.43 52.53.155.43

British J Pharmacology - 2023 - Han-html.html

1
1. scibot 16 Aug 2023
  
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  RRID:AB_330403
  
  DOI: 10.1111/bph.16208
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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52.53.155.43/5e554e9cedd6e38ae632f7a8eb735fb3080af333/British J Pharmacology - 2023 - Han-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia

1
1. scibot 10 Aug 2023
  
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  RRID:AB_330403
  
  DOI: 10.1158/2159-8290.CD-22-1396
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10401075/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching

1
1. scibot 27 Jul 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2023.112868
  
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sciencedirect.com/science/article/pii/S2211124723008793
Jun 2023
www.sciencedirect.com www.sciencedirect.com

New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation

1
1. scibot 08 Jun 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.chembiol.2023.05.007
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2451945623001502
May 2023
www.sciencedirect.com www.sciencedirect.com

Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma

1
1. scibot 20 May 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.bcp.2023.115612
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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sciencedirect.com/science/article/pii/S0006295223002034
journals.aai.org journals.aai.org

cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway

1
1. scibot 13 May 2023
  
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  AB_330403
  
  DOI: 10.4049/jimmunol.2200351
  
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journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
www.sciencedirect.com www.sciencedirect.com

Exercise-derived peptide protects against pathological cardiac remodeling

1
1. scibot 05 May 2023
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.ebiom.2022.104164
  
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sciencedirect.com/science/article/pii/S2352396422003450
Mar 2023
52.53.155.43 52.53.155.43

943-html.html

1
1. scibot 16 Mar 2023
  
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  RRID:AB_330403
  
  DOI: 10.1158/1078-0432.ccr-22-1763
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
  Curator: @scibot
  
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52.53.155.43/c8f103b982e67ed0e9f7f2acbda462e2c6f6fa27/943-html.html
May 2022
pubs.acs.org pubs.acs.org

Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance

1
1. scibot 24 May 2022
  
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  RRID:AB_330403
  
  DOI: 10.1021/acs.biomac.2c00256
  
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pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
Apr 2022
academic.oup.com academic.oup.com

GH action in prostate cancer cells promotes proliferation limits apoptosis and regulates cancer-related gene expression

1
1. scibot 29 Apr 2022
  
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  RRID:AB_330403
  
  DOI: 10.1210/endocr/bqac031
  
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academic.oup.com/endo/article/163/5/bqac031/6564019
www.nature.com www.nature.com

Identifying a confused cell identity for esophageal squamous cell carcinoma

1
1. scibot 23 Apr 2022
  
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  RRID:AB_330403
  
  DOI: 10.1038/s41392-022-00946-8
  
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nature.com/articles/s41392-022-00946-8
Mar 2022
journals.lww.com journals.lww.com

Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

1
1. scibot 10 Mar 2022
  
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  RRID:AB_330403
  
  DOI: 10.4103/1673-5374.335165
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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journals.lww.com/nrronline/Fulltext/2022/17090/Ruxolitinib_attenuates_secondary_injury_after.35.aspx
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Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling

1
1. scibot 02 Mar 2022
  
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  RRID:AB_33040
  
  DOI: 10.1016/j.isci.2022.103833
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_330403
  
  Curator comments: Phospho-Jak2 (Tyr1007/1008) Antibody Cell Signaling Technology Cat# 3771
  
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  RRIDCUR:Unresolved RRIDCUR:Incorrect RRID:AB_330403
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sciencedirect.com/science/article/pii/S2589004222001031
Nov 2021
elifesciences.org elifesciences.org

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

1
1. scibot 24 Nov 2021
  
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  RRID:AB_330403
  
  DOI: 10.7554/eLife.65109
  
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elifesciences.org/articles/65109
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

1
1. scibot 23 Oct 2021
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.isci.2021.103173
  
  Resource: (Cell Signaling Technology Cat# 3771, RRID:AB_330403)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8517841/
Jun 2021
www.hindawi.com www.hindawi.com

Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition

1
1. scibot 29 Jun 2021
  
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  AB_330403
  
  DOI: 10.1155/2021/6687089
  
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hindawi.com/journals/mi/2021/6687089/tab2/
May 2021
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An active marine halophenol derivative attenuates lipopolysaccharide-induced acute liver injury in mice by improving M2 macrophage-mediated therapy

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1. scibot 29 May 2021
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.intimp.2021.107676
  
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sciencedirect.com/science/article/pii/S156757692100312X
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RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

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1. scibot 12 May 2021
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2021.109102
  
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sciencedirect.com/science/article/pii/S2211124721004368
Mar 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 13 Mar 2021
  
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  RRID:AB_330403
  
  DOI: 10.1111/bph.15357
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15357
Jan 2021
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Critical role of Syk-dependent STAT1 activation in innate antiviral immunity

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1. scibot 20 Jan 2021
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2020.108627
  
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sciencedirect.com/science/article/pii/S2211124720316168
Sep 2020
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Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function

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1. scibot 26 Sep 2020
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.immuni.2020.07.006
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7398039/
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

A chalcone derivative, 1m‐6, exhibits atheroprotective effects by increasing cholesterol efflux and reducing inflammation‐induced endothelial dysfunction

1
1. scibot 23 Sep 2020
  
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  RRID:AB_330403
  
  DOI: 10.1111/bph.15175
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15175
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Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation

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1. scibot 16 Sep 2020
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2020.107875
  
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sciencedirect.com/science/article/pii/S2211124720308561
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The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis

1
1. scibot 16 Sep 2020
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2020.108158
  
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sciencedirect.com/science/article/pii/S2211124720311475
Jan 2020
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Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease

1
1. scibot 13 Jan 2020
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2019.06.054
  
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sciencedirect.com/science/article/pii/S2211124719308277
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_330403
  
  DOI: 10.1016/j.celrep.2019.04.066
  
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sciencedirect.com/science/article/pii/S221112471930539X
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

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1. scibot 05 Nov 2018
  
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europepmc.org europepmc.org

Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5736349/