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Jul 2025
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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

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Mar 2025
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Effective targeting of PDGFRA-altered high-grade glioma with avapritinib

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IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202501593
Feb 2025
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Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases

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pmc.ncbi.nlm.nih.gov/articles/PMC11866499/
Apr 2024
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The complete Kaposi sarcoma-associated herpesvirus genome induces early-onset, metastatic angiosarcoma in transgenic mice

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cell.com/cell-host-microbe/fulltext/S1931-3128(24)00112-4
Dec 2023
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Epinephrine inhibits PI3Kα via the Hippo kinases

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Aug 2023
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Short-term PI3K inhibition prevents breast cancer in preclinical models

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Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib treatment in patients with BRAF-mutant melanoma brain metastases

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ncbi.nlm.nih.gov/pmc/articles/PMC9898142/
Jun 2023
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Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells

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nature.com/articles/s41417-023-00637-8
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Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities

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aacrjournals.org/cancerres/article/83/6/890/718574/Olig1-2-Expressing-Intermediate-Lineage
Apr 2023
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Deletion of the tyrosine phosphatase Shp2 in cervical cancer cells promotes reprogramming of glutamine metabolism

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  DOI: 10.1096/fj.202202078RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202078RR
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Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells

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sciencedirect.com/science/article/pii/S2211124723003881
Feb 2023
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Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy

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  DOI: 10.1016/j.isci.2023.106064
  
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sciencedirect.com/science/article/pii/S2589004223001414
Jan 2023
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Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma

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ncbi.nlm.nih.gov/pmc/articles/PMC9359717/
Oct 2022
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Increased GH secretion and body growth in mice carrying ablation of IGF-1 receptor in GH-releasing hormone cells

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1. scibot 25 Oct 2022
  
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  DOI: 10.1210/endocr/bqac151
  
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academic.oup.com/endo/article/163/11/bqac151/6696879
Jun 2022
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Phosphorylation and stabilization of PD-L1 by CK2 suppresses dendritic cell function

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aacrjournals.org/cancerres/article/82/11/2185/699105/Phosphorylation-and-Stabilization-of-PD-L1-by-CK2
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Effects of the isolated and combined ablation of growth hormone and IGF-1 receptors in somatostatin neurons

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1. scibot 03 Jun 2022
  
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  DOI: 10.1210/endocr/bqac045
  
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academic.oup.com/endo/article/163/5/bqac045/6565600
Mar 2022
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Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus

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  DOI: 10.1016/j.ebiom.2022.103903
  
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sciencedirect.com/science/article/pii/S2352396422000871
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Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

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sciencedirect.com/science/article/pii/S1097276522001101
Nov 2021
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CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development

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sciencedirect.com/science/article/pii/S2211124721014856
Aug 2021
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Untitled document

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Untitled document

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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Jul 2021
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Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice

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1. scibot 30 Jul 2021
  
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2. scibot 28 Jul 2021
  
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academic.oup.com/endo/article/160/1/193/5185194
Jan 2020
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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

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A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation

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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

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WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

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Protein kinase B mediates insulin‐like growth factor 1‐induced phosphorylation and nuclear export of histone deacetylase 5 via NADPH oxidase 4 activation in vascular smooth muscle cells

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  DOI: 10.1002/jcp.28353
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.28353
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Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice

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academic.oup.com/endo/article/160/1/193/5185194
Nov 2018
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Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

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sciencedirect.com/science/article/pii/S1535610818302174
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Untitled document

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5722612/
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Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

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sciencedirect.com/science/article/pii/S153561081730507X
Nov 2017
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IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots

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academic.oup.com/endo/article/158/10/3488/4037400/IGFBP4-Is-Required-for-Adipogenesis-and-Influences