212 Matching Annotations
  1. Oct 2026
  2. www.sciencedirect.com www.sciencedirect.com
    α-Herpesviruses exploit host ssDNA gap prevention pathways for GC-rich genome replication and reactivation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726011228
  3. Sep 2026
  4. www.biorxiv.org www.biorxiv.org
    KLF4 promotes apoptosis evasion and PARP inhibitor resistance in BRCA2-mutated epithelial ovarian cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.64898/2026.08.23.746472v1
  5. Aug 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining fruquintinib with TAS-102 as a promising strategy: antitumor activity in preclinical colorectal and gastric cancer xenograft models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13422279/
  7. Jul 2026
  8. www.sciencedirect.com www.sciencedirect.com
    SUDS3 nuclear condensates decelerate DNA replication and safeguard genome stability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726007916
  9. www.sciencedirect.com www.sciencedirect.com
    Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379126003393
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TNIK overexpression is sufficient for chemoradiation resistance in limited-stage small cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13339944/
  11. Jun 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLX4IP limits replication stress globally and at ALT telomeres
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13269807/
  13. www.nature.com www.nature.com
    Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41598-026-46639-y
  14. www.sciencedirect.com www.sciencedirect.com
    FANCA-dependent FEN1 recruitment suppresses transcription-replication conflicts and PARPi sensitivity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276526003515
  15. www.nature.com www.nature.com
    DNA replication stress and translational repression converge to drive CDK1- and caspase-dependent apoptosis in Ewing sarcoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41388-026-03845-2
  16. www.sciencedirect.com www.sciencedirect.com
    The WEE1 inhibitor azenosertib broadly enhances efficacy of antibody-drug conjugates with topoisomerase I and microtubule inhibitor payloads
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004226017657
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclin E modulates vulnerability to CDC7 kinase inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13243581/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FET Fusion Oncoproteins Disrupt Physiologic DNA Repair and Create a Targetable Opportunity for ATR Inhibitor Therapy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13223543/
  19. May 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptive Regulation of dNTP Homeostasis Confers Osimertinib Resistance in EGFR-Mutant Non–Small Cell Lung Carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13198874/
  21. Apr 2026
  22. www.sciencedirect.com www.sciencedirect.com
    The cytotoxic effect of prexasertib is a consequence of dual inhibition on both CHK1 and AMPK
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945626001121
  23. www.sciencedirect.com www.sciencedirect.com
    Efficacy, safety, and biomarker analysis of datopotamab deruxtecan in advanced non-small cell lung cancer: ICARUS-LUNG01 phase 2 study
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610826001716
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC13065833/
  25. Mar 2026
  26. www.biorxiv.org www.biorxiv.org
    PRMT5 is Frequently Upregulated and a Potential Therapeutic Target in MTAP-deficient Malignant Peripheral Nerve Sheath Tumors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.64898/2026.03.09.710638v1
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CF10 Displays Improved Synergy with Oxaliplatin in TP53-Null and Wild-Type CRC Cells from Increased Top1cc and Replication Stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12984549/
  28. www.sciencedirect.com www.sciencedirect.com
    Ski2-like helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726001294
  29. Feb 2026
  30. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226004876-main-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    54.241.53.176/5315f690103a419b51b9848013b3d4fea487be7e/1-s2.0-S2589004226004876-main-html.html
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12900515/
  32. www.sciencedirect.com www.sciencedirect.com
    Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124726000197
  33. www.sciencedirect.com www.sciencedirect.com
    Targeting ATR signaling in sarcoma with homologous recombination deficiency
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0304383526000637
  34. Jan 2026
  35. 54.241.53.176 54.241.53.176
    2026.01.09.698661v1.full-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    54.241.53.176/229f150d292937106a4e15fcfbf1923f59503af0/2026.01.09.698661v1.full-html.html
  36. www.sciencedirect.com www.sciencedirect.com
    The FANCD2-FANCI heterodimer coordinates chromatin openness and cell cycle progression throughout DNA double-strand break repair
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112472501602X
  37. www.sciencedirect.com www.sciencedirect.com
    Exploiting the polypharmacology of alectinib for synergistic RNA splicing disruption with RBM39 degraders
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725015566
  38. Dec 2025
  39. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com:5037/science/article/pii/S2211124725015177
  40. Nov 2025
  41. 54.241.53.176 54.241.53.176
    2025.11.06.687028v2.full-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    54.241.53.176/c5747531de041288b038c2a31e89061fc2d84331/2025.11.06.687028v2.full-html.html
  42. Oct 2025
  43. www.biorxiv.org www.biorxiv.org
    L-asparaginase treatment induces a tumor metabolic plasticity and reveals a vulnerability to PARP1/2 inhibitor Olaparib, in B-cell lymphomas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2025.10.24.683536v1
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the ERα DBD-LBD interface with mitoxantrone disrupts receptor function through proteasomal degradation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12496009/
  45. www.sciencedirect.com www.sciencedirect.com
    DNA damage checkpoints balance a tradeoff between diploid- and polyploid-derived arrest failures
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725011192
  46. Sep 2025
  47. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422501781X-main-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/f995d4046e40952b58ad424165ec4ce7948925e5/1-s2.0-S258900422501781X-main-html.html
  48. www.sciencedirect.com www.sciencedirect.com
    TELS1 stabilizes t-loops independently of TRF2 and controls telomere length in pluripotent cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725010319
  49. Aug 2025
  50. www.sciencedirect.com www.sciencedirect.com
    PARP inhibitors potentiate proton therapy end-of-range effects by accelerating replication forks and promoting transcription conflict
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0360301625061978
  51. www.sciencedirect.com www.sciencedirect.com
    53BP1 regulates p53-E2F7-dependent transcriptional gene repression and participates in the Fanconi anemia pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725009234
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12314526/
  53. Jul 2025
  54. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610825002612
  55. Jun 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC12240685/
  57. May 2025
  58. www.sciencedirect.com www.sciencedirect.com
    Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2090123225002772
  59. Apr 2025
  60. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/fb744ae1c201e64705cbba4fb67640ca74ff97a4/PDF-html.html
  61. www.sciencedirect.com www.sciencedirect.com
    The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725003766
  62. Mar 2025
  63. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202410718
  64. Feb 2025
  65. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Combined inhibition of ribonucleotide reductase and WEE1 induces synergistic anticancer activity in Ewing’s sarcoma cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    bmccancer.biomedcentral.com/articles/10.1186/s12885-025-13691-2
  66. www.sciencedirect.com www.sciencedirect.com
    Unraveling AURKB as a potential therapeutic target in pulmonary hypertension using integrated transcriptomic analysis and pre-clinical studies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379125000370
  67. 52.53.155.43 52.53.155.43
    A non-catalytic function for Rad18 in sustaining glioblastoma proliferation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/bd241f9d9f184fcec259e1abcded858c2c8c9686/2024.09.05.611406.full-html.html
  68. Dec 2024
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional and functional regulation of cell cycle and UV response by PPARβ in human skin epidermal cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11610672/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
  71. Nov 2024
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11532780/
  73. www.sciencedirect.com www.sciencedirect.com
    Distinct effects of sacituzumab govitecan and berzosertib on DNA damage response in ovarian cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004224025082
  74. www.sciencedirect.com www.sciencedirect.com
    A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379124005949
  75. www.sciencedirect.com www.sciencedirect.com
    Acute multi-level response to defective de novo chromatin assembly in S-phase
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276524008633
  76. Oct 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276524007767
  78. Sep 2024
  79. www.sciencedirect.com www.sciencedirect.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867424009115
  80. Aug 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11315672/
  82. Jun 2024
  83. www.cell.com www.cell.com
    Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/iscience/abstract/S2589-0042(24)01357-9
  84. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/iscience/abstract/S2589-0042(24)01200-8
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11169917/
  86. www.sciencedirect.com www.sciencedirect.com
    The ribotoxic stress response drives UV-mediated cell death
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867424005270
  87. www.sciencedirect.com www.sciencedirect.com
    Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580724003277
  88. May 2024
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11099347/
  90. Apr 2024
  91. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
  92. www.sciencedirect.com www.sciencedirect.com
    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724003528
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
  94. www.sciencedirect.com www.sciencedirect.com
    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867424002502
  95. Mar 2024
  96. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276524001758
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10933359/
  98. Feb 2024
  99. aacrjournals.org aacrjournals.org
    A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/clincancerres/article/29/24/5047/731678/A-Phase-I-Expansion-Cohort-Study-Evaluating-the
  100. www.sciencedirect.com www.sciencedirect.com
    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379124000570
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10873513/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10527942/
  103. www.sciencedirect.com www.sciencedirect.com
    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124724001062
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10810864/
  106. Jan 2024
  107. www.sciencedirect.com www.sciencedirect.com
    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379123006055
  108. www.sciencedirect.com www.sciencedirect.com
    Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723016674
  109. Dec 2023
  110. www.sciencedirect.com www.sciencedirect.com
    Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223027360
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10734389/
  112. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379123005438
  113. www.sciencedirect.com www.sciencedirect.com
    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S109727652300967X
  114. 52.53.155.43 52.53.155.43
    ccr-23-2005-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/8373d350712629607ae5ff64c6434e7646ebbbe9/ccr-23-2005-html.html
  115. Nov 2023
  116. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pubmed.ncbi.nlm.nih.gov/37279095/
  117. www.sciencedirect.com www.sciencedirect.com
    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723013190
  118. Oct 2023
  119. www.sciencedirect.com www.sciencedirect.com
    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723011920
  120. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
  121. www.sciencedirect.com www.sciencedirect.com
    Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723011567
  122. Sep 2023
  123. 52.53.155.43 52.53.155.43
    can-22-3646-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/7c5c0394bd7eaeefd5e70a237f23894cb3f7190b/can-22-3646-html.html
  124. Aug 2023
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10441460/
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10434289/
  127. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
  128. 52.53.155.43 52.53.155.43
    crc-23-0268-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/385511300daa3e14cefdae67d8cec9d074c7314f/crc-23-0268-html.html
  129. 52.53.155.43 52.53.155.43
    SSRN-id4513724-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/5f78fb6f419d1fcb5e4cfbd3ef5a02650af33ba6/SSRN-id4513724-html.html
  130. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223015262
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10380721/
  132. Jul 2023
  133. www.sciencedirect.com www.sciencedirect.com
    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723008161
  134. www.sciencedirect.com www.sciencedirect.com
    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276523004720
  135. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610823002179
  136. 52.53.155.43 52.53.155.43
    ccr-23-0103-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
  137. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723007325
  138. Jun 2023
  139. www.sciencedirect.com www.sciencedirect.com
    Detection of endogenous translesion DNA synthesis in single mammalian cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2667237523001303
  140. www.sciencedirect.com www.sciencedirect.com
    DHX9-mediated pathway contributes to the malignant phenotype of Myelodysplastic syndromes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223010398
  141. www.sciencedirect.com www.sciencedirect.com
    PTBP1 enforces ATR-CHK1 signalling determining the potency of CDC7 inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223010283
  142. www.sciencedirect.com www.sciencedirect.com
    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276523003714
  143. May 2023
  144. www.sciencedirect.com www.sciencedirect.com
    p53-independent tumor suppression by cell-cycle arrest via CREB/ATF transcription factor OASIS
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723004904
  145. www.sciencedirect.com www.sciencedirect.com
    HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723005077
  146. www.sciencedirect.com www.sciencedirect.com
    ATR protects centromere identity by promoting DAXX association with PML nuclear bodies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723005065
  147. Apr 2023
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10104471/
  149. www.science.org www.science.org
    Polymerase iota (Pol ι) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    science.org/doi/10.1126/sciadv.ade7997
  150. www.sciencedirect.com www.sciencedirect.com
    Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723004114
  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10066556/
  152. Mar 2023
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10066556/
  154. www.sciencedirect.com www.sciencedirect.com
    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723003078
  155. www.sciencedirect.com www.sciencedirect.com
    Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124723002103
  156. Jan 2023
  157. www.sciencedirect.com www.sciencedirect.com
    Cytosolic DNA sensing by cGAS/STING promotes TRPV2-mediated Ca2+ release to protect stressed replication forks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522012175
  158. www.sciencedirect.com www.sciencedirect.com
    Cyclin E-induced replicative stress drives p53-dependent whole-genome duplication
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867422015793
  159. Nov 2022
  160. academic.oup.com academic.oup.com
    Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    academic.oup.com/narcancer/article/4/4/zcac036/6825304
  161. Aug 2022
  162. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004222012160
  163. Jul 2022
  164. www.sciencedirect.com www.sciencedirect.com
    Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722008798
  165. Jun 2022
  166. www.sciencedirect.com www.sciencedirect.com
    MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722006544
  167. May 2022
  168. www.sciencedirect.com www.sciencedirect.com
    DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522003938
  169. Apr 2022
  170. www.sciencedirect.com www.sciencedirect.com
    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522002684
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8971416/
  172. Mar 2022
  173. www.sciencedirect.com www.sciencedirect.com
    BMI-1 regulates DNA end resection and homologous recombination repair
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722002777
  174. www.sciencedirect.com www.sciencedirect.com
    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S153458072200079X
  175. Jan 2022
  176. www.sciencedirect.com www.sciencedirect.com
    WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721017733
  177. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721017459
  178. www.sciencedirect.com www.sciencedirect.com
    ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721017204
  179. Dec 2021
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8260463/
  181. www.sciencedirect.com www.sciencedirect.com
    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413121005398
  182. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721015461
  183. Nov 2021
  184. www.cell.com www.cell.com
    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8594940/
  186. Oct 2021
  187. www.sciencedirect.com www.sciencedirect.com
    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S109727652100798X
  188. link.springer.com link.springer.com
    Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    link.springer.com/article/10.1186/s13046-021-02124-0
  189. www.sciencedirect.com www.sciencedirect.com
    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721012791
  190. www.sciencedirect.com www.sciencedirect.com
    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276521007504
  191. Sep 2021
  192. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
  193. Aug 2021
  194. www.sciencedirect.com www.sciencedirect.com
    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610821003834
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6205844/
  196. europepmc.org europepmc.org
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    europepmc.org/articles/PMC6292694/
  197. www.jbc.org www.jbc.org
    Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    jbc.org/content/294/6/1763.full
  198. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276518303459
  199. Jul 2021
  200. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP277367
  201. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610817304178
  202. www.sciencedirect.com www.sciencedirect.com
    Preclinical study using androgen receptor (AR) degradation enhancer to increase radiotherapy efficacy via targeting radiation-increased AR to better suppress prostate cancer progression
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2352396418306273
  203. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519303168
  204. www.sciencedirect.com www.sciencedirect.com
    An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666166721003841
  205. www.sciencedirect.com www.sciencedirect.com
    FANCI functions as a repair/apoptosis switch in response to DNA crosslinks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1534580721005177
  206. Jun 2021
  207. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2352396421002346
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
  209. May 2021
  210. www.sciencedirect.com www.sciencedirect.com
    Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520309564
  211. www.sciencedirect.com www.sciencedirect.com
    TopBP1 assembles nuclear condensates to switch on ATR signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520309916
  212. www.sciencedirect.com www.sciencedirect.com
    CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520306912
  213. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520305190
  214. www.sciencedirect.com www.sciencedirect.com
    Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520304299
  215. www.sciencedirect.com www.sciencedirect.com
    Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520304767
  216. www.sciencedirect.com www.sciencedirect.com
    HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520302732
  217. Apr 2021
  218. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610821001161
  219. Mar 2021
  220. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC7969873/
  221. www.sciencedirect.com www.sciencedirect.com
    Alternative lengthening of telomeres is a self-perpetuating process in ALT-associated PML bodies
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520309515
  222. Feb 2021
  223. www.sciencedirect.com www.sciencedirect.com
    CARM1 regulates replication fork speed and stress response by stimulating PARP1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520309023
  224. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867420316147
  225. www.sciencedirect.com www.sciencedirect.com
    Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276521000046
  226. elifesciences.org elifesciences.org
    The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/61797
  227. Jan 2021
  228. www.sciencedirect.com www.sciencedirect.com
    A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720316648
  229. Dec 2020
  230. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520308984
  231. www.sciencedirect.com www.sciencedirect.com
    Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720314388
  232. www.cell.com www.cell.com
    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cell.com/molecular-cell/fulltext/S1097-2765(20)30723-1
  233. Oct 2020
  234. www.sciencedirect.com www.sciencedirect.com
    MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590920304501
  235. Sep 2020
  236. www.sciencedirect.com www.sciencedirect.com
    ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720310858
  237. www.sciencedirect.com www.sciencedirect.com
    FBXW7 Confers Radiation Survival by Targeting p53 for Degradation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719316821
  238. mcr.aacrjournals.org mcr.aacrjournals.org
    Constitutive CHK1 expression drives a pSTAT3-CIP2A circuit that promotes glioblastoma cell survival and growth
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mcr.aacrjournals.org/content/18/5/709
  239. www.sciencedirect.com www.sciencedirect.com
    Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720300929
  240. Aug 2020
  241. www.sciencedirect.com www.sciencedirect.com
    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124720307257
  242. Jan 2020
  243. www.sciencedirect.com www.sciencedirect.com
    IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519304332
  244. www.sciencedirect.com www.sciencedirect.com
    C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519304794
  245. www.sciencedirect.com www.sciencedirect.com
    The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719314834
  246. www.sciencedirect.com www.sciencedirect.com
    PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519307683
  247. www.sciencedirect.com www.sciencedirect.com
    The SUMO Isopeptidase SENP6 Functions as a Rheostat of Chromatin Residency in Genome Maintenance and Chromosome Dynamics
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719311684
  248. www.sciencedirect.com www.sciencedirect.com
    Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719308162
  249. www.sciencedirect.com www.sciencedirect.com
    Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1934590919302759
  250. www.sciencedirect.com www.sciencedirect.com
    Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S221112471930974X
  251. www.sciencedirect.com www.sciencedirect.com
    ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719311854
  252. www.sciencedirect.com www.sciencedirect.com
    Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719314500
  253. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519301042
  254. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276518310062
  255. www.sciencedirect.com www.sciencedirect.com
    MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519301029
  256. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC6292694/
  257. www.sciencedirect.com www.sciencedirect.com
    Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519302734
  258. www.sciencedirect.com www.sciencedirect.com
    Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719306060
  259. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276518310621
  260. www.sciencedirect.com www.sciencedirect.com
    DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610819300996
  261. www.sciencedirect.com www.sciencedirect.com
    Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276518310979
  262. Nov 2018
  263. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124718315055
  264. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124718314529
  265. www.sciencedirect.com www.sciencedirect.com
    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276518306051
  266. www.sciencedirect.com www.sciencedirect.com
    ATR-Mediated Global Fork Slowing and Reversal Assist Fork Traverse and Prevent Chromosomal Breakage at DNA Interstrand Cross-Links
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124718312737
  267. www.sciencedirect.com www.sciencedirect.com
    Histone Ubiquitination by the DNA Damage Response Is Required for Efficient DNA Replication in Unperturbed S Phase
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276518305586