45 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Burdock miR8175 in diet improves insulin resistance induced by obesity in mice through food absorption
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    1. scibot 28 Apr 2024
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      DOI: 10.1016/j.isci.2024.109705

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039404/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109540

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993184/
  4. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114007

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    sciencedirect.com/science/article/pii/S2211124724003358
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.cmet.2023.10.018

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    sciencedirect.com/science/article/pii/S1550413123004126
  7. Nov 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Insulin receptor loss impairs mammary tumorigenesis in mice
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    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113251

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    sciencedirect.com/science/article/pii/S2211124723012639
  9. Sep 2023
  10. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Dai-html.html
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    1. scibot 16 Sep 2023
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      DOI: 10.1111/bph.16238

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    52.53.155.43/8d076c70ed36377d24eb7bc3686db861bc15751d/British J Pharmacology - 2023 - Dai-html.html
  11. Jul 2023
  12. dx.doi.org dx.doi.org
    Pigment Epithelium-Derived Factor, a Novel Adipokine, Contributes to Gestational Diabetes Mellitus
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1210/clinem/dgad413

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    dx.doi.org/10.1210/clinem/dgad413
  13. Mar 2023
  14. www.sciencedirect.com www.sciencedirect.com
    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.cmet.2023.03.004

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    sciencedirect.com/science/article/pii/S1550413123000827
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
    1
    1. scibot 05 Mar 2023
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      DOI: 10.1158/1541-7786.MCR-22-0090

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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  16. Jan 2023
  17. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111984

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    sciencedirect.com/science/article/pii/S2211124722018885
  18. Dec 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
    1
    1. scibot 24 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111834

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    sciencedirect.com/science/article/pii/S2211124722017260
  20. Nov 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.crmeth.2022.100338

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    sciencedirect.com/science/article/pii/S2667237522002351
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
    1
    1. scibot 19 Nov 2022
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      DOI: 10.1158/2767-9764.crc-22-0256

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648418/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect
    1
    1. scibot 04 Nov 2022
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      DOI: 10.3389/fendo.2022.951928

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    ncbi.nlm.nih.gov/pmc/articles/PMC9627217/
  24. Oct 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.isci.2022.105233

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    ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
  26. Mar 2022
  27. www.sciencedirect.com www.sciencedirect.com
    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110548

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    sciencedirect.com/science/article/pii/S2211124722002893
  28. www.nature.com www.nature.com
    Symmetric and asymmetric receptor conformation continuum induced by a new insulin
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1038/s41589-022-00981-0

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    nature.com/articles/s41589-022-00981-0
  29. www.sciencedirect.com www.sciencedirect.com
    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
    1
    1. scibot 16 Mar 2022
      RRID:AB_331253

      DOI: 10.1016/j.celrep.2022.110509

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    sciencedirect.com/science/article/pii/S2211124722002455
  30. Dec 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Translational and post-translational control of human naïve versus primed pluripotency
    1
    1. scibot 30 Dec 2021
      RRID:AB_331253

      DOI: 10.1016/j.isci.2021.103645

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    sciencedirect.com/science/article/pii/S2589004221016151
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
    1
    1. scibot 17 Dec 2021
      RRID:AB_331253

      DOI: 10.3389/fphys.2021.779547

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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  33. Oct 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation
    1
    1. scibot 13 Oct 2021
      RRID:AB_331253

      DOI: 10.1016/j.celrep.2021.109821

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    sciencedirect.com/science/article/pii/S2211124721012857
  35. Aug 2021
  36. www.sciencedirect.com www.sciencedirect.com
    An extensive and dynamic trans-omic network illustrating prominent regulatory mechanisms in response to insulin in the liver
    1
    1. scibot 25 Aug 2021
      RRID:AB_331253

      DOI: 10.1016/j.celrep.2021.109569

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    sciencedirect.com/science/article/pii/S2211124721010032
  37. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
    1
    1. scibot 14 Aug 2021
      RRID:AB_331253

      DOI: 10.1210/en.2019-00177

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    academic.oup.com/endo/article/160/11/2692/5551999
  38. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 12 Aug 2021
      RRID:AB_331253

      DOI: 10.1111/bph.14553

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14553
  39. www.sciencedirect.com www.sciencedirect.com
    Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
    1
    1. scibot 04 Aug 2021
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      DOI: 10.1016/j.cmet.2021.07.010

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    sciencedirect.com/science/article/pii/S1550413121003260
  40. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 03 Aug 2021
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      DOI: 10.1111/bph.14553

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14553
  41. Jan 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3
    1
    1. scibot 08 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108576

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    sciencedirect.com/science/article/pii/S2211124720315655
  43. Sep 2020
  44. www.jbc.org www.jbc.org
    Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet–induced hepatic steatosis and insulin resistance by elevating IL-18 levels
    1
    1. scibot 17 Sep 2020
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      DOI: 10.1074/jbc.RA119.011840

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    jbc.org/content/295/31/10842.full
  45. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
    1
    1. scibot 15 Sep 2020
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      DOI: 10.1016/j.devcel.2020.06.039

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    pubmed.ncbi.nlm.nih.gov/32710848/
  46. www.sciencedirect.com www.sciencedirect.com
    Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
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    1. scibot 11 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107780

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    sciencedirect.com/science/article/pii/S2211124720307609
  47. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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    1. scibot 03 Sep 2020
      Rabbit anti-phospho-IGF-1R

      DOI: 10.3390/cells9010147

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    mdpi.com/2073-4409/9/1/147
  48. journals.physiology.org journals.physiology.org
    Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner | American Journal of Physiology-Endocrinology and Metabolism
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    1. scibot 03 Sep 2020
      monoclonal rabbit phospho-IGF-I receptor β (Tyr1135/1136)/insulin receptor-β

      DOI: 10.1152/ajpendo.00473.2019

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    journals.physiology.org/doi/full/10.1152/ajpendo.00473.2019
  49. Jan 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
    1
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      DOI: 10.1016/j.ebiom.2019.08.033

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    sciencedirect.com/science/article/pii/S2352396419305584
  51. www.sciencedirect.com www.sciencedirect.com
    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.09.004

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    sciencedirect.com/science/article/pii/S2211124719311726
  52. www.sciencedirect.com www.sciencedirect.com
    Lysosome Positioning Influences mTORC2 and AKT Signaling
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.05.009

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    sciencedirect.com/science/article/pii/S1097276519303624
  53. www.sciencedirect.com www.sciencedirect.com
    Contrasting Effects of IGF Binding Protein-3 Expression in Mammary Tumor Cells and the Tumor Microenvironment
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.yexcr.2018.11.006

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    sciencedirect.com/science/article/pii/S0014482718308218
  54. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_331253

      DOI: 10.1016/j.celrep.2019.02.081

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    sciencedirect.com/science/article/pii/S2211124719302670
  55. Nov 2018
  56. www.sciencedirect.com www.sciencedirect.com
    Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818303763
  57. www.sciencedirect.com www.sciencedirect.com
    In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver
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