76 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intra-tumoral YAP and TAZ heterogeneity drives collective NSCLC invasion that is targeted by SUMOylation inhibitor TAK-981
    1
    1. scibot 15 Nov 2024
      RRID:AB_331405

      DOI: 10.1016/j.isci.2024.111133

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    pmc.ncbi.nlm.nih.gov/articles/PMC11544388/
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Nitrous oxide induces hypothermia and TrkB activation: Maintenance of body temperature abolishes antidepressant-like effects in mice
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1016/j.neuropharm.2024.110172

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    sciencedirect.com/science/article/pii/S0028390824003411
  5. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.xcrm.2024.101752

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    sciencedirect.com/science/article/pii/S2666379124004828
  6. Sep 2024
  7. www.sciencedirect.com www.sciencedirect.com
    “β-Hydroxybutyrate Recapitulates the Beneficial Effects of Ketogenic Metabolic Therapy in Polycystic Kidney Disease”
    1
    1. scibot 25 Sep 2024
      AB_331405

      DOI: 10.1016/j.isci.2024.110773

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    sciencedirect.com/science/article/pii/S2589004224019989
  8. Aug 2024
  9. www.embopress.org www.embopress.org
    EDC3 phosphorylation regulates growth and invasion through controlling P‐body formation and dynamics
    1
    1. scibot 02 Aug 2024
      anti‐phospho‐GSK3B

      DOI: 10.15252/embr.202050835

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    embopress.org/doi/full/10.15252/embr.202050835
  10. pubs.acs.org pubs.acs.org
    Linking Hypothermia and Altered Metabolism with TrkB Activation
    1
    1. scibot 02 Aug 2024
      RRID:AB_331405

      DOI: 10.1021/acschemneuro.3c00350

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    pubs.acs.org/doi/full/10.1021/acschemneuro.3c00350
  11. Jul 2024
  12. www.embopress.org www.embopress.org
    Non-canonical NF-κB signaling limits the tolerogenic β-catenin-Raldh2 axis in gut dendritic cells to exacerbate intestinal pathologies
    1
    1. scibot 30 Jul 2024
      AB_331405

      DOI: 10.1038/s44318-024-00182-6

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    embopress.org/doi/10.1038/s44318-024-00182-6
  13. Jun 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation
    1
    1. scibot 21 Jun 2024
      RRID:AB_331405

      DOI: 10.1016/j.isci.2024.110199

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    sciencedirect.com/science/article/pii/S258900422401424X
  15. May 2024
  16. 52.53.155.43 52.53.155.43
    PIIS2589004224013336-html.html
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.isci.2024.110108

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    52.53.155.43/201eeea7517d8f69343e1388322eb99416c3ef0f/PIIS2589004224013336-html.html
  17. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
    1
    1. scibot 04 May 2024
      AB_331405

      DOI: 10.1101/2024.01.21.576568

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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  18. Feb 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity
    1
    1. scibot 27 Feb 2024
      Cell Signaling Technology#9336

      DOI: 10.1016/j.isci.2024.109121

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    sciencedirect.com/science/article/pii/S2589004224003420
  20. www.sciencedirect.com www.sciencedirect.com
    β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models
    1
    1. scibot 02 Feb 2024
      RRID:AB_331405

      DOI: 10.1016/j.biopha.2024.116217

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    sciencedirect.com/science/article/pii/S0753332224000982
  21. link.springer.com link.springer.com
    The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism
    1
    1. scibot 01 Feb 2024
      RRID:AB_331405

      DOI: 10.1007/s00213-024-06530-y

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    link.springer.com/article/10.1007/s00213-024-06530-y
  22. Jan 2024
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Akt activation ameliorates deficits in hippocampal-dependent memory and activity-dependent synaptic protein synthesis in an Alzheimer’s disease mouse model
    1
    1. scibot 06 Jan 2024
      RRID:AB_331405

      DOI: 10.1016/j.jbc.2023.105619

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    pmc.ncbi.nlm.nih.gov/articles/PMC10839450/
  24. Aug 2023
  25. 52.53.155.43 52.53.155.43
    SSRN-id4493933-html.html
    1
    1. scibot 10 Aug 2023
      RRID:AB_331405

      DOI: 10.2139/ssrn.4493933

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    52.53.155.43/08c4dbafd821964dea682c937a91353f8c556b6a/SSRN-id4493933-html.html
  26. Jul 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
    1
    1. scibot 14 Jul 2023
      RRID:AB_331405

      DOI: 10.1016/j.ccell.2023.06.007

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    sciencedirect.com/science/article/pii/S1535610823002179
  28. Jun 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
    1
    1. scibot 09 Jun 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2023.112616

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    sciencedirect.com/science/article/pii/S2211124723006277
  30. academic.oup.com academic.oup.com
    Increased fibrosis in white adipose tissue of male and female bGH transgenic mice appears independent of TGF-β action
    1
    1. scibot 02 Jun 2023
      AB_331405

      DOI: 10.1210/endocr/bqad038

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    academic.oup.com/endo/article/164/5/bqad038/7069260
  31. May 2023
  32. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
    1
    1. scibot 25 May 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2023.112536

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    sciencedirect.com/science/article/pii/S2211124723005478
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity
    1
    1. scibot 18 May 2023
      RRID:AB_331405

      DOI: 10.1210/jendso/bvad057

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    ncbi.nlm.nih.gov/pmc/articles/PMC10185814/
  34. www.nature.com www.nature.com
    Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
    1
    1. scibot 06 May 2023
      RRID:AB_331405

      DOI: 10.1038/s41467-023-38165-6

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    nature.com/articles/s41467-023-38165-6
  35. Apr 2023
  36. www.nature.com www.nature.com
    Sex difference in evolution of cognitive decline: studies on mouse model and the Dominantly Inherited Alzheimer Network cohort
    1
    1. scibot 18 Apr 2023
      RRID:AB_331405

      DOI: 10.1038/s41398-023-02411-8

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    nature.com/articles/s41398-023-02411-8
  37. Mar 2023
  38. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
    1
    1. scibot 02 Mar 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2023.112188

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    sciencedirect.com/science/article/pii/S2211124723001997
  39. Feb 2023
  40. www.mdpi.com www.mdpi.com
    CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2
    1
    1. scibot 15 Feb 2023
      RRID:AB_331405

      DOI: 10.3390/cells12040555

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    mdpi.com/2073-4409/12/4/555
  41. Jan 2023
  42. www.nature.com www.nature.com
    Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model
    1
    1. scibot 19 Jan 2023
      RRID:AB_331405

      DOI: 10.1038/s42003-022-04387-5

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    nature.com/articles/s42003-022-04387-5
  43. www.sciencedirect.com www.sciencedirect.com
    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
    1
    1. scibot 12 Jan 2023
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2022.111984

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    sciencedirect.com/science/article/pii/S2211124722018885
  44. Dec 2022
  45. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
    1
    1. scibot 08 Dec 2022
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2022.111759

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    sciencedirect.com/science/article/pii/S2211124722016424
  46. Nov 2022
  47. www.researchsquare.com www.researchsquare.com
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    1. scibot 11 Nov 2022
      RRID:AB_331405

      DOI: 10.21203/rs.3.rs-658360/v1

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    2. scibot 11 Nov 2022
      RRID:AB_331405

      DOI: 10.21203/rs.3.rs-658360/v1

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    3. scibot 11 Nov 2022
      RRID:AB_331405

      DOI: 10.21203/rs.3.rs-658360/v1

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    researchsquare.com/
  48. Oct 2022
  49. www.sciencedirect.com www.sciencedirect.com
    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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    1. scibot 28 Oct 2022
      RRID:AB_331405

      DOI: 10.1016/j.cell.2022.09.033

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    sciencedirect.com/science/article/pii/S0092867422012521
  50. Sep 2022
  51. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
    1
    1. scibot 27 Sep 2022
      RRID:AB_331405

      DOI: 10.1016/j.jbc.2022.102532

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    sciencedirect.com/science/article/pii/S0021925822009759
  52. Aug 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
    1
    1. scibot 23 Aug 2022
      RRID:AB_331405

      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  54. Jul 2022
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered amyloid precursor protein, tau-regulatory proteins, neuronal numbers and behaviour, but no tau pathology, synaptic and inflammatory changes or memory deficits, at 1-month following repetitive mild traumatic brain injury
    1
    1. scibot 27 Jul 2022
      AB_331405

      DOI: 10.1111/ejn.15752

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    onlinelibrary.wiley.com/doi/10.1111/ejn.15752
  56. Jun 2022
  57. academic.oup.com academic.oup.com
    Influence of maternal exercise on glucose and lipid metabolism in offspring stem cells: ENHANCED by Mom
    1
    1. scibot 03 Jun 2022
      RRID:AB_331405

      DOI: 10.1210/clinem/dgac270

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac270/6577152
  58. May 2022
  59. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    1. scibot 05 May 2022
      RRID:AB_331405

      DOI: 10.1186/s13024-022-00526-y

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    link.springer.com/article/10.1186/s13024-022-00526-y
  60. Feb 2022
  61. www.sciencedirect.com www.sciencedirect.com
    A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia
    1
    1. scibot 13 Feb 2022
      Cell signaling, Cat#9336

      DOI: 10.1016/j.jbc.2022.101716

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    sciencedirect.com/science/article/pii/S0021925822001569
  62. Oct 2021
  63. www.sciencedirect.com www.sciencedirect.com
    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
    1
    1. scibot 21 Oct 2021
      RRID:AB_331405

      DOI: 10.1016/j.celrep.2021.109854

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    sciencedirect.com/science/article/pii/S2211124721013218
  64. Sep 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice
    1
    1. scibot 28 Sep 2021
      RRID:AB_331405

      DOI: 10.1016/j.isci.2021.103089

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    ncbi.nlm.nih.gov/pmc/articles/PMC8449244/
  66. Aug 2021
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Leukemia associated RUNX1T1 gene reduced proliferation and invasiveness of glioblastoma cells
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    1. scibot 11 Aug 2021
      9336

      DOI: 10.1002/jcb.30126

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  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pathology of nNOS expressing GABAergic neurons in mouse model of Alzheimer’s disease
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  71. Jul 2021
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    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KY19382, a novel activator of Wnt/β‐catenin signalling, promotes hair regrowth and hair follicle neogenesis
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy
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  77. May 2021
  78. www.sciencedirect.com www.sciencedirect.com
    PSD-95 deficiency alters GABAergic inhibition in the prefrontal cortex
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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  81. Mar 2021
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  83. Feb 2021
  84. academic.oup.com academic.oup.com
    Maternal high fat diet multigenerationally impairs hippocampal synaptic plasticity and memory in male rat offspring
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  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA‐34a causes ceramide accumulation and effects insulin signaling pathway by targeting ceramide kinase (CERK) in aging skeletal muscle
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  86. Jan 2021
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  88. Dec 2020
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The cGMP system in normal and degenerating mouse neuroretina: New proteins with cGMP interaction potential identified by a proteomics approach
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      Rabbit anti‐p‐GSK3β (Ser 9)

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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non‐disease‐specific pathway of functional neurologic improvement
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  91. Sep 2020
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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  93. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    β2‐adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy
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  94. www.mdpi.com www.mdpi.com
    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      rabbit anti-phospho-GSK-3β

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  95. Jan 2020
  96. www.sciencedirect.com www.sciencedirect.com
    Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling
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    SFRPs Are Biphasic Modulators of Wnt-Signaling-Elicited Cancer Stem Cell Properties beyond Extracellular Control
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  98. academic.oup.com academic.oup.com
    Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
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    Light Entrains Diurnal Changes in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons
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  101. Nov 2018
  102. www.sciencedirect.com www.sciencedirect.com
    Juvenile treatment with mGluR2/3 agonist prevents schizophrenia-like phenotypes in adult by acting through GSK3β
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    FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2
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    Pathology of nNOS expressing GABAergic neurons in mouse model of Alzheimer’s disease
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex
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    Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
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  107. Nov 2017
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    Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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  110. www.nature.com www.nature.com
    ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury
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  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brief isoflurane anesthesia regulates striatal AKT‐GSK3β signaling and ameliorates motor deficits in a rat model of early‐stage Parkinson′s disease
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    TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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