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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling
    7
    1. scibot 22 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_331439
    2. scibot 21 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    3. scibot 20 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_331439
    4. scibot 19 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    5. scibot 18 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_331439
    6. scibot 17 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_331439
    7. scibot 16 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    sciencedirect.com/science/article/pii/S2589004224026713
  3. Dec 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling
    2
    1. scibot 15 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_331439
    2. scibot 14 Dec 2024
      RRID:AB_331439

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    sciencedirect.com/science/article/pii/S2589004224026713
  5. www.sciencedirect.com www.sciencedirect.com
    Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit
    1
    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.xcrm.2024.101868

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    sciencedirect.com/science/article/pii/S2666379124006396
  6. www.nature.com www.nature.com
    GEFT inhibits the GSDM-mediated proptosis signalling pathway, promoting the progression and drug resistance of rhabdomyosarcoma
    1
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      DOI: 10.1038/s41419-024-07243-y

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    A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control
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      DOI: 10.1016/j.immuni.2024.10.010

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    sciencedirect.com/science/article/pii/S1074761324004904
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    Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury
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    1. scibot 02 Dec 2024
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    sciencedirect.com/science/article/pii/S1931312824004086
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    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
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    sciencedirect.com/science/article/pii/S2211124724013743
  10. Oct 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKMYT1 Is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer
    1
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      DOI: 10.1158/1535-7163.MCT-23-0564

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  12. aacrjournals.org aacrjournals.org
    Conophylline Inhibits Hepatocellular Carcinoma by Inhibiting Activated Cancer-associated Fibroblasts Through Suppression of G Protein–coupled Receptor 68
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    1. scibot 02 Oct 2024
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      DOI: 10.1158/1535-7163.MCT-20-0150

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    aacrjournals.org/mct/article/20/6/1019/673256/Conophylline-Inhibits-Hepatocellular-Carcinoma-by
  13. Sep 2024
  14. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Sodium butyrate prevents cytokine-induced β-cell dysfunction through restoration of stromal interaction molecule 1 expression and activation of store-operated calcium entry
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1096/fj.202302501RR

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    Activation of the NLRP1B inflammasome by caspase-8
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      DOI: 10.1038/s42003-024-06882-3

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    Combination treatment with hyaluronic acid synthesis and Bcl-2 inhibitors induces senolytic elimination of oral squamous cell carcinoma cells in vitro.
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    sciencedirect.com/science/article/pii/S2212555824001649
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding the neurotoxic effects of propofol: insights into the RARα-Snhg1-Bdnf regulatory cascade
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      DOI: 10.1152/ajpcell.00547.2023

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  18. 52.53.155.43 52.53.155.43
    Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
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    1. scibot 05 Sep 2024
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
  20. Aug 2024
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
    1
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    sciencedirect.com/science/article/pii/S2211124724009914
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    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
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    sciencedirect.com/science/article/pii/S0378874124009498
  23. josr-online.biomedcentral.com josr-online.biomedcentral.com
    Overexpression of FGF2 delays the progression of osteonecrosis of the femoral head activating the PI3K/Akt signaling pathway
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    Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent Mice
    1
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      caspase-3

      DOI: 10.3390/cells10050996

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  25. Jul 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
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      DOI: 10.1016/j.chembiol.2024.06.014

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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    wang-et-al-2024-lilrb1-hla-g-axis-defines-a-checkpoint-driving-natural-killer-cell-exhaustion-in-tuberculosis-html.html
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  28. www.embopress.org www.embopress.org
    LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis
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      DOI: 10.1038/s44321-024-00106-1

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    embopress.org/doi/10.1038/s44321-024-00106-1
  29. www.cell.com www.cell.com
    Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis
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      DOI: 10.1016/j.celrep.2024.114453

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    cell.com/cell-reports/fulltext/S2211-1247(24)00782-4
  30. Jun 2024
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
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      DOI: 10.1016/j.cell.2024.05.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
  32. www.sciencedirect.com www.sciencedirect.com
    Neurodegeneration and glial morphological changes are both prevented by TRPM2 inhibition during the progression of a Parkinson's disease mouse model
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      DOI: 10.1016/j.expneurol.2024.114780

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    sciencedirect.com/science/article/pii/S0014488624001067
  33. www.sciencedirect.com www.sciencedirect.com
    Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
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      DOI: 10.1016/j.celrep.2024.114287

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    sciencedirect.com/science/article/pii/S2211124724006156
  34. May 2024
  35. www.mdpi.com www.mdpi.com
    N-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents
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      DOI: 10.3390/cancers16112033

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    mdpi.com/2072-6694/16/11/2033
  36. 52.53.155.43 52.53.155.43
    Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor
    1
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      DOI: 10.1101/2024.02.15.580435

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    52.53.155.43/e49e13012caa173776051da0a73c8b285e75644e/2024.02.15.580435v1.full-html.html
  37. www.mdpi.com www.mdpi.com
    Cell-Membrane-Coated Metal–Organic Framework Nanocarrier Combining Chemodynamic Therapy for the Inhibition of Hepatocellular Carcinoma Proliferation
    1
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      DOI: 10.3390/pharmaceutics16050619

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    mdpi.com/1999-4923/16/5/619
  38. www.sciencedirect.com www.sciencedirect.com
    Targeted blocking of EGFR and GLUT1 by compound H reveals a new strategy for treatment of triple-negative breast cancer and nasopharyngeal carcinoma
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      9662

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    sciencedirect.com/science/article/pii/S0928098724001003
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease
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      DOI: 10.1002/jnr.25337

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    onlinelibrary.wiley.com/doi/10.1002/jnr.25337
  40. Apr 2024
  41. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
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      RRID:AB_331439

      DOI: 10.1083/jcb.202303141

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      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
  42. www.sciencedirect.com www.sciencedirect.com
    Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development
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      DOI: 10.1016/j.stem.2024.03.011

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    sciencedirect.com/science/article/pii/S1934590924000924
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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    Epigenetic disruption of histone deacetylase-2 accelerated apoptotic signaling and retarded malignancy in gastric cells
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    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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  52. Feb 2024
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  58. Jan 2024
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    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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  62. Dec 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Deacetylase Inhibitors Prevent Cytokine-Induced β Cell Dysfunction Through Restoration of Stromal Interaction Molecule 1 Expression and Activation of Store-Operated Calcium Entry
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  79. Oct 2023
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    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma
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  91. Jul 2023
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    Maternal dietary deficiencies in folic acid or choline worsen stroke outcomes in adult male and female mouse offspring
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    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
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    Low-Field Magnetic Stimulation Alleviates MPTP-Induced Alterations in Motor Function and Dopaminergic Neurons in Male Mice
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    Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”
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    Whole-genome CRISPR screen identifies RAVER1 regulates RIPK1-mediated inflammatory cell death, PANoptosis
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    Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
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    Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations
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  104. Apr 2023
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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    Tumor microenvironment mimicking 3D models unveil the multifaceted effects of SMAC mimetics
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  110. Mar 2023
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    Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration
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    Physical exercise modulates the microglial complement pathway in mice to relieve cortical circuitry deficits induced by mutant human TDP-43
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    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
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    Bile acids target mitofusin 2 to differentially regulate innate immunity in physiological versus cholestatic conditions
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    GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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    Early alveolar epithelial cell necrosis is a potential driver of COVID-19-induced acute respiratory distress syndrome
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  122. Dec 2022
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    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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  134. Oct 2022
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  138. Sep 2022
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    cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease
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  140. journals.biologists.com journals.biologists.com
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    Combined treatment of marizomib and cisplatin modulates cervical cancer growth and invasion and enhances antitumor potential in vitro and in vivo
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    Meprin β expression modulates the interleukin-6 mediated JAK2-STAT3 signaling pathway in ischemia/reperfusion-induced kidney injury
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    Synergistic effect of mild traumatic brain injury and alcohol aggravates neuroinflammation, amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations: Impact on psychological stress
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  145. Aug 2022
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    TMEM16F may be a new therapeutic target for Alzheimer’s... : Neural Regeneration Research
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  151. Jul 2022
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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    Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation
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    Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptors
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    Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma
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    Regulating DNA methylation could reduce neuronal ischemia response and apoptosis after ischemia-reperfusion injury
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  165. May 2022
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    AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma
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    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
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    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
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    Caveolin-1 Peptide Regulates p53-microRNA-34a Feedback in Fibrotic Lung Fibroblasts
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    The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
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  180. Feb 2022
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    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
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    miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation
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    DsbA-L interacts with VDAC1 in mitochondrion-mediated tubular cell apoptosis and contributes to the progression of acute kidney disease
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    Emodin inhibits the proliferation and migration of B16F10 cells and induces their apoptosis
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
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  186. Jan 2022
  187. www.sciencedirect.com www.sciencedirect.com
    A stress-reduced passaging technique improves the viability of human pluripotent cells
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    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
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    Inhibition of TRPM2 by AG490 Is Neuroprotective in a Parkinson’s Disease Animal Model
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    Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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  193. Dec 2021
  194. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway
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    Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer
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    Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways
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    Microvilli-derived extracellular vesicles carry Hedgehog morphogenic signals for Drosophila wing imaginal disc development
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    Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages
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    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
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  200. Nov 2021
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    Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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    Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
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    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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    Chronic VEGFR-3 signaling preserves dendritic arborization and sensitization under stress
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    A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3′-processing and termination
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    TrkB‐mediated activation of the phosphatidylinositol‐3‐kinase/Akt cascade reduces the damage inflicted by oxygen‐glucose deprivation in area CA3 of the rat hippocampus
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  212. www.tandfonline.com www.tandfonline.com
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  214. Jul 2021
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    Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death
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      Rabbit polyclonal anti-Caspase-3

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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  217. elifesciences.org elifesciences.org
    NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
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      rabbit polyclonal anti-Caspase-3

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  219. academic.oup.com academic.oup.com
    Prolonged Exposure to Insulin Inactivates Akt and Erk1/2 and Increases Pancreatic Islet and INS1E β-Cell Apoptosis
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    Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140
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  221. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  222. www.tandfonline.com www.tandfonline.com
    Caprine herpesvirus 1 (CpHV-1) as a potential candidate for oncolytic virotherapy
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  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
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  224. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  225. www.nature.com www.nature.com
    Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC
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  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular adhesion molecule-1-induced post-traumatic brain injury neuropathology in the prefrontal cortex and hippocampus leads to sensorimotor function deficits and psychological stress
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    Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm
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