28 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
    1
    1. scibot 25 Sep 2024
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2024.114606

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    ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer
    1
    1. scibot 06 Jul 2024
      RRID:AB_331460

      DOI: 10.3892/or.2024.8760

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    ncbi.nlm.nih.gov/pmc/articles/PMC11223027/
  5. Feb 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation
    1
    1. scibot 18 Feb 2024
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2024.113782

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    sciencedirect.com/science/article/pii/S2211124724001104
  7. Oct 2023
  8. www.cell.com www.cell.com
    PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C
    1
    1. scibot 06 Oct 2023
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2023.113041

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    cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
  9. Jan 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway
    1
    1. scibot 11 Jan 2023
      RRID:AB_331460

      DOI: 10.1016/j.isci.2022.105806

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827073/
  11. Oct 2022
  12. www.sciencedirect.com www.sciencedirect.com
    A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1
    1
    1. scibot 12 Oct 2022
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2022.111475

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    sciencedirect.com/science/article/pii/S2211124722013250
  13. May 2022
  14. www.sciencedirect.com www.sciencedirect.com
    The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development
    1
    1. scibot 13 May 2022
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2022.110789

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    sciencedirect.com/science/article/pii/S2211124722005563
  15. Jan 2022
  16. www.sciencedirect.com www.sciencedirect.com
    WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
    1
    1. scibot 19 Jan 2022
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2021.110261

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    sciencedirect.com/science/article/pii/S2211124721017733
  17. Dec 2021
  18. www.sciencedirect.com www.sciencedirect.com
    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
    1
    1. scibot 01 Dec 2021
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2021.110060

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    sciencedirect.com/science/article/pii/S2211124721015461
  19. Sep 2021
  20. www.sciencedirect.com www.sciencedirect.com
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
    1
    1. scibot 25 Sep 2021
      RRID:AB_331460

      DOI: 10.1016/j.xcrm.2021.100394

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    sciencedirect.com/science/article/pii/S2666379121002524
  21. Jul 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 31 Jul 2021
      RRID:AB_331460

      DOI: 10.1016/j.cub.2018.09.059

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    ncbi.nlm.nih.gov/pmc/articles/PMC6287978/
  23. pubs.acs.org pubs.acs.org
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
    1
    1. scibot 28 Jul 2021
      AB_331460

      DOI: 10.1021/acsptsci.9b00001

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    pubs.acs.org/doi/full/10.1021/acsptsci.9b00001
  24. May 2021
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    14–3-3γ prevents centrosome duplication by inhibiting NPM1 function
    1
    1. scibot 20 May 2021
      phospho-CDK1

      DOI: 10.1111/gtc.12848

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    onlinelibrary.wiley.com/doi/10.1111/gtc.12848
  26. www.sciencedirect.com www.sciencedirect.com
    CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress
    1
    1. scibot 07 May 2021
      RRID:AB_331460

      DOI: 10.1016/j.molcel.2020.10.008

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    sciencedirect.com/science/article/pii/S1097276520306912
  27. Mar 2021
  28. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
    1
    1. scibot 03 Mar 2021
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2021.108808

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    sciencedirect.com/science/article/pii/S2211124721001224
  29. Dec 2020
  30. www.sciencedirect.com www.sciencedirect.com
    Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation
    1
    1. scibot 24 Dec 2020
      RRID:AB_331460

      DOI: 10.1016/j.cub.2020.11.058

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    sciencedirect.com/science/article/pii/S0960982220317711
  31. Sep 2020
  32. www.sciencedirect.com www.sciencedirect.com
    The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation
    1
    1. scibot 26 Sep 2020
      RRID:AB_331460

      DOI: 10.1016/j.celrep.2020.107901

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    sciencedirect.com/science/article/pii/S2211124720308822
  33. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
    1
    1. scibot 16 Sep 2020
      RRID:AB_331460

      DOI: 10.1016/j.ccell.2020.04.002

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    sciencedirect.com/science/article/pii/S1535610820301641
  34. www.sciencedirect.com www.sciencedirect.com
    The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis
    1
    1. scibot 12 Sep 2020
      RRID:AB_331460

      DOI: 10.1016/j.cub.2019.12.053

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    sciencedirect.com/science/article/pii/S0960982219316860
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
    1
    1. scibot 04 Sep 2020
      RRID, AB_331460

      DOI: 10.1021/acsptsci.9b00001

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7088890/
  36. Jan 2020
  37. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      RRID:AB_331460

      DOI: 10.1016/j.cub.2018.09.059

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      RRID:AB_331460 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0960982218312843
  38. Nov 2018
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_331460

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    ncbi.nlm.nih.gov/pmc/articles/PMC6085539/
  40. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_331460

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    sciencedirect.com/science/article/pii/S235239641830238X
  41. www.nature.com www.nature.com
    Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death
    1
    1. scibot 05 Nov 2018
      RRID:AB_331460

      Curator: @evieth

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    nature.com/articles/s41420-018-0044-7
  42. Nov 2017
  43. www.sciencedirect.com www.sciencedirect.com
    The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior
    1
    1. scibot 08 Nov 2017
      AB_331460

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S2352396417301585
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDK Substrate Phosphorylation and Ordering the Cell Cycle
    2
    1. scibot 08 Nov 2017
      RRID: AB_331460

      Curator: @bandrow

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    2. scibot 08 Nov 2017
      AB_331460

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    ncbi.nlm.nih.gov/pmc/articles/PMC5161751/table/undtbl1/
  45. www.sciencedirect.com www.sciencedirect.com
    CDK Substrate Phosphorylation and Ordering the Cell Cycle
    1
    1. scibot 08 Nov 2017
      AB_331460

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867416316063