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Cyclin E modulates vulnerability to CDC7 kinase inhibition

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1. scibot 13 Jun 2026
  
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  DOI: 10.1038/s41389-026-00613-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13243581/
Dec 2025
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Jub-induced phosphorylation of Warts inhibits its activity and recruitment into biomolecular condensates

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  DOI: 10.1016/j.celrep.2025.116647
  
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sciencedirect.com:5037/science/article/pii/S2211124725014196
Jul 2025
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The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation

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1. scibot 24 Jul 2025
  
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sciencedirect.com/science/article/pii/S2211124725007909
Apr 2025
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Evidence of substrate control of Cdk phosphorylation during the budding yeast cell cycle

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  DOI: 10.1016/j.celrep.2025.115534
  
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sciencedirect.com/science/article/pii/S2211124725003055
Mar 2025
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Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers

1
1. scibot 25 Mar 2025
  
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  DOI: 10.1016/j.canlet.2025.217665
  
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sciencedirect.com/science/article/pii/S0304383525002319
Feb 2025
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OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival

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  DOI: 10.1038/s44319-024-00361-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
Jan 2025
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Revisiting phosphoregulation of Cdc25C during M-phase induction

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  DOI: 10.1016/j.isci.2024.111603
  
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sciencedirect.com/science/article/pii/S258900422402830X
Nov 2024
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Acute multi-level response to defective de novo chromatin assembly in S-phase

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1. scibot 14 Nov 2024
  
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sciencedirect.com/science/article/pii/S1097276524008633
Sep 2024
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GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114606
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
Jul 2024
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Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer

1
1. scibot 06 Jul 2024
  
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  DOI: 10.3892/or.2024.8760
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11223027/
Feb 2024
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Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation

1
1. scibot 18 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113782
  
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sciencedirect.com/science/article/pii/S2211124724001104
Oct 2023
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PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

1
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  DOI: 10.1016/j.celrep.2023.113041
  
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cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
Jan 2023
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Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway

1
1. scibot 11 Jan 2023
  
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  DOI: 10.1016/j.isci.2022.105806
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9827073/
Oct 2022
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A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1

1
1. scibot 12 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111475
  
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sciencedirect.com/science/article/pii/S2211124722013250
May 2022
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The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

1
1. scibot 13 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110789
  
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sciencedirect.com/science/article/pii/S2211124722005563
Jan 2022
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WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

1
1. scibot 19 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110261
  
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sciencedirect.com/science/article/pii/S2211124721017733
Dec 2021
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CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment

1
1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110060
  
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sciencedirect.com/science/article/pii/S2211124721015461
Sep 2021
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CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

1
1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.xcrm.2021.100394
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
Jul 2021
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Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.cub.2018.09.059
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6287978/
pubs.acs.org pubs.acs.org

Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

1
1. scibot 28 Jul 2021
  
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  AB_331460
  
  DOI: 10.1021/acsptsci.9b00001
  
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pubs.acs.org/doi/full/10.1021/acsptsci.9b00001
May 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

14–3-3γ prevents centrosome duplication by inhibiting NPM1 function

1
1. scibot 20 May 2021
  
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  phospho-CDK1
  
  DOI: 10.1111/gtc.12848
  
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onlinelibrary.wiley.com/doi/10.1111/gtc.12848
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CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress

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  DOI: 10.1016/j.molcel.2020.10.008
  
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sciencedirect.com/science/article/pii/S1097276520306912
Mar 2021
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MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity

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1. scibot 03 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108808
  
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sciencedirect.com/science/article/pii/S2211124721001224
Dec 2020
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Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation

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1. scibot 24 Dec 2020
  
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  DOI: 10.1016/j.cub.2020.11.058
  
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sciencedirect.com/science/article/pii/S0960982220317711
Sep 2020
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The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation

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sciencedirect.com/science/article/pii/S2211124720308822
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

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sciencedirect.com/science/article/pii/S1535610820301641
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The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis

1
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  DOI: 10.1016/j.cub.2019.12.053
  
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sciencedirect.com/science/article/pii/S0960982219316860
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Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

1
1. scibot 04 Sep 2020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7088890/
Jan 2020
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Untitled document

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  DOI: 10.1016/j.cub.2018.09.059
  
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sciencedirect.com/science/article/pii/S0960982218312843
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6085539/
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Untitled document

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sciencedirect.com/science/article/pii/S235239641830238X
www.nature.com www.nature.com

Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death

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1. scibot 05 Nov 2018
  
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nature.com/articles/s41420-018-0044-7
Nov 2017
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The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S2352396417301585
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CDK Substrate Phosphorylation and Ordering the Cell Cycle

2
1. scibot 08 Nov 2017
  
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  AB_331460
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5161751/table/undtbl1/
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CDK Substrate Phosphorylation and Ordering the Cell Cycle

1
1. scibot 08 Nov 2017
  
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  AB_331460
  
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  SciCrunch record: RRID:AB_331460
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_331460 RRIDCUR:Validated
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Tags

RRIDCUR:Validated

RRID:AB_331460

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867416316063