34 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
    1
    1. scibot 11 Dec 2024
      RRID:AB_331472

      DOI: 10.1158/2159-8290.CD-23-0866

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
    1
    1. scibot 16 Nov 2024
      RRID:AB_331472

      DOI: 10.1158/1535-7163.MCT-23-0904

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532780/
  5. Sep 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
    1
    1. scibot 25 Sep 2024
      RRID:AB_2141156

      DOI: 10.1016/j.ccell.2020.02.002

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    sciencedirect.com/science/article/pii/S153561082030091X
  7. Jul 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
    1
    1. scibot 17 Jul 2024
      AB_331472

      DOI: 10.1016/j.celrep.2024.114510

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    sciencedirect.com/science/article/pii/S2211124724008398
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
    1
    1. scibot 24 May 2024
      RRID:AB_331472

      DOI: 10.1016/j.ccell.2024.05.002

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    sciencedirect.com/science/article/pii/S1535610824001636
  11. Mar 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
    1
    1. scibot 06 Mar 2024
      RRID:AB_331472

      DOI: 10.1158/1535-7163.MCT-23-0025

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  13. Nov 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
    1
    1. scibot 27 Nov 2023
      RRID:AB_331472

      DOI: 10.1016/j.molcel.2021.03.003

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    sciencedirect.com/science/article/pii/S1097276521001714
  15. Sep 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Palbociclib releases the latent differentiation capacity of neuroblastoma cells
    1
    1. scibot 30 Sep 2023
      RRID:AB_331472

      DOI: 10.1016/j.devcel.2023.08.028

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    sciencedirect.com/science/article/pii/S1534580723004434
  17. Aug 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
    1
    1. scibot 31 Aug 2023
      RRID:AB_331472

      DOI: 10.21203/rs.3.rs-3182731/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10441460/
  19. 52.53.155.43 52.53.155.43
    mct-23-0025 (1)-html.html
    1
    1. scibot 11 Aug 2023
      RRID:AB_331472

      DOI: 10.1158/1535-7163.mct-23-0025

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    52.53.155.43/1629e82c15a2ef751662f24158b1c1b52e5a2112/mct-23-0025 (1)-html.html
  20. Jul 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
    1
    1. scibot 06 Jul 2023
      RRID:AB_331472

      DOI: 10.1158/1535-7163.MCT-22-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response
    1
    1. scibot 27 Jun 2023
      RRID:AB_331472

      DOI: 10.1016/j.isci.2023.107090

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    sciencedirect.com/science/article/pii/S2589004223011677
  24. Aug 2022
  25. www.sciencedirect.com www.sciencedirect.com
    The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells
    1
    1. scibot 10 Aug 2022
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2022.111170

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    sciencedirect.com/science/article/pii/S2211124722009834
  26. Mar 2022
  27. www.nature.com www.nature.com
    Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma
    1
    1. scibot 05 Mar 2022
      RRID:AB_331472

      DOI: 10.1038/s41467-022-28515-1

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    nature.com/articles/s41467-022-28515-1
  28. www.sciencedirect.com www.sciencedirect.com
    Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
    1
    1. scibot 02 Mar 2022
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2022.110444

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    sciencedirect.com/science/article/pii/S2211124722001711
  29. Oct 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells
    1
    1. scibot 13 Oct 2021
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2021.109808

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    sciencedirect.com/science/article/pii/S2211124721012687
  31. Aug 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2018.11.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC6350781/
  33. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 01 Aug 2021
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2018.11.006

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    sciencedirect.com/science/article/pii/S2211124718317352
  34. Jul 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
    1
    1. scibot 30 Jul 2021
      RRID:AB_331472

      DOI: 10.1016/j.cell.2018.09.051

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    sciencedirect.com/science/article/pii/S0092867418312637
  36. May 2021
  37. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
    1
    1. scibot 07 May 2021
      RRID:AB_331472

      DOI: 10.1016/j.molcel.2020.04.027

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    sciencedirect.com/science/article/pii/S1097276520302690
  38. Apr 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
    1
    1. scibot 02 Apr 2021
      RRID:AB_331472

      DOI: 10.1016/j.molcel.2021.03.003

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    sciencedirect.com/science/article/pii/S1097276521001714
  40. Jan 2021
  41. www.sciencedirect.com www.sciencedirect.com
    A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
    1
    1. scibot 27 Jan 2021
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2020.108675

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    sciencedirect.com/science/article/pii/S2211124720316648
  42. Oct 2020
  43. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Marine Alkaloid, Ascomylactam A, Suppresses Lung Tumorigenesis via Inducing Cell Cycle G1/S Arrest through ROS/Akt/Rb Pathway
    1
    1. scibot 03 Oct 2020
      RRID:AB_331472

      DOI: 10.3390/md18100494

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    pubmed.ncbi.nlm.nih.gov/32992455/
  44. Sep 2020
  45. www.sciencedirect.com www.sciencedirect.com
    CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma
    1
    1. scibot 16 Sep 2020
      RRID:AB_331472

      DOI: 10.1016/j.ccell.2020.01.007

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    sciencedirect.com/science/article/pii/S1535610820300465
  46. www.sciencedirect.com www.sciencedirect.com
    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
    1
    1. scibot 10 Sep 2020
      RRID:AB_331472

      DOI: 10.1016/j.molcel.2019.12.022

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    sciencedirect.com/science/article/pii/S1097276519309529
  47. Jan 2020
  48. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_331472

      DOI: 10.1016/j.cmet.2018.11.014

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    sciencedirect.com/science/article/pii/S1550413118306910
  49. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance
    1
    1. scibot 12 Jan 2020
      RRID:AB_331472

      DOI: 10.1016/j.celrep.2019.02.023

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    sciencedirect.com/science/article/pii/S2211124719301937
  50. Nov 2018
  51. www.sciencedirect.com www.sciencedirect.com
    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
    1
    1. scibot 05 Nov 2018
      RRID:AB_331472

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2211124718315675
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints
    1
    1. scibot 05 Nov 2018
      807/811

      Curator: @anp055

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    ncbi.nlm.nih.gov/pmc/articles/PMC3635462/
  53. www.sciencedirect.com www.sciencedirect.com
    β-Hydroxybutyrate Prevents Vascular Senescence through hnRNP A1-Mediated Upregulation of Oct4
    1
    1. scibot 05 Nov 2018
      RRID:AB_331472

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518306051
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_331472

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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  55. Nov 2017
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 08 Nov 2017
      RRID:AB_331472

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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  57. www.sciencedirect.com www.sciencedirect.com
    Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug
    1
    1. scibot 08 Nov 2017
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    sciencedirect.com/science/article/pii/S2405471217303319
  58. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 08 Nov 2017
      AB_331472

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    sciencedirect.com/science/article/pii/S2405471216304082