173 Matching Annotations
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    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    QDPR deficiency drives immune suppression in pancreatic cancer
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  4. Apr 2024
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
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    sciencedirect.com/science/article/pii/S0092867424002502
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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  7. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
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    sciencedirect.com/science/article/pii/S1097276524001758
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    The zinc-finger protein Z4 cooperates with condensin II to regulate somatic chromosome pairing and 3D chromatin organization
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      DOI: 10.1093/nar/gkae198

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    Eukaryotic release factor 1 from Euplotes promotes frameshifting at premature stop codons in human cells
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  11. Feb 2024
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    FOXA1 forms biomolecular condensates that unpack condensed chromatin to function as a pioneer factor
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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  14. Jan 2024
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
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    Repression of latent NF-κB enhancers by PDX1 regulates β cell functional heterogeneity
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  19. Dec 2023
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    Subcytoplasmic location of translation controls protein output
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    An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling
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    cd-22-1301-html.html
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  23. Oct 2023
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    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
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    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
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    Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
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  28. Sep 2023
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    Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice
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  30. Aug 2023
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
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    Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine
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    Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1
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  35. Jul 2023
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    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
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    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
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    sciencedirect.com/science/article/pii/S0896627323004658
  39. Jun 2023
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    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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    Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models
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  42. May 2023
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    HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
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  44. Apr 2023
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    Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
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    Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression
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    Somatic chromosome pairing has a determinant impact on 3D chromatin organization
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    biorxiv.org/content/10.1101/2023.03.29.534693v1
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    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
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    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  50. Mar 2023
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    Targeting Mutant Dicer Tumorigenesis in Pleuropulmonary Blastoma via Inhibition of RNA Polymerase I
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    Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington’s disease
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    Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity
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    Human RECQL4 represses the RAD52‐mediated single‐strand annealing pathway after ionizing radiation or cisplatin treatment
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    The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding
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    Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
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    Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis
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    jneurosci.org/content/38/4/803
  198. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA
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    sciencedirect.com/science/article/pii/S0092867417314307
  199. www.sciencedirect.com www.sciencedirect.com
    CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis
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    sciencedirect.com/science/article/pii/S1097276517306561
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    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
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    sciencedirect.com/science/article/pii/S0092867417312448
  201. europepmc.org europepmc.org
    Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.
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      RRID:AB_331563

      Curator: @evieth

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  202. Nov 2017
  203. dev.biologists.org dev.biologists.org
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    dev.biologists.org/content/144/18/3232
  204. www.sciencedirect.com www.sciencedirect.com
    Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival
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    1. scibot 08 Nov 2017
      AB_331563

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1097276517302356
  205. www.sciencedirect.com www.sciencedirect.com
    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
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    1. scibot 08 Nov 2017
      AB_331563

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S0092867417305378
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    Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis
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    1. scibot 08 Nov 2017
      AB_331563

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S0092867417304889
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    Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9
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    1. scibot 08 Nov 2017
      AB_331563

      Curator: @Zeljana_Babic

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  208. www.sciencedirect.com www.sciencedirect.com
    Decreased adult neurogenesis in hibernating Syrian hamster
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    1. scibot 08 Nov 2017
      9715

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S0306452216303219