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TCN2 Drives Psoriasis-Like Inflammation and Keratinocyte Hyperproliferation, Correlating With IL-1β and STAT3 Activation

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1. scibot 07 Jul 2026
  
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  DOI: 10.1096/fj.202600470R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202600470R
Jun 2026
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Hepatitis B virus promotes hepatocellular carcinogenesis by activating IL-6-dependent tumor-macrophage crosstalk and M2-like macrophage polarization

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.jbc.2026.113283
  
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sciencedirect.com/science/article/pii/S0021925826021551
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Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.016
  
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sciencedirect.com/science/article/pii/S107476132600227X
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A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state

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1. scibot 13 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.015
  
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sciencedirect.com/science/article/pii/S1074761326002268
Mar 2026
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Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic Reprogramming

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1. scibot 18 Mar 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0695
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12990994/
Dec 2025
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circATF6 triggers calcium overload to synergize with EGFR-TKI in non-small cell lung cancer via modulation of proteostasis

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116659
  
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sciencedirect.com:5037/science/article/pii/S2211124725014317
Nov 2025
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An mTOR-Stat3-Stathmin pathway controls centrosome and microtubule dynamics for oocyte polarization

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.cub.2025.10.085
  
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sciencedirect.com:5037/science/article/pii/S0960982225014666
Jul 2025
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A STAT3/integrin axis accelerates pancreatic cancer initiation and progression

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1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116010
  
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sciencedirect.com/science/article/pii/S2211124725007818
May 2025
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Stromal lipid species dictate melanoma metastasis and tropism

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.001
  
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sciencedirect.com/science/article/pii/S1535610825001382
Apr 2025
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Hypothalamic PNOC/NPY neurons constitute mediators of leptin-controlled energy homeostasis

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.04.001
  
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sciencedirect.com/science/article/pii/S0092867425004039
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Growth Hormone-Releasing Hormone Antagonists Increase Radiosensitivity in Non-Small Cell Lung Cancer Cells

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1. scibot 16 Apr 2025
  
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  DOI: 10.3390/ijms26073267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11990011/
Mar 2025
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ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity

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1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115397
  
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sciencedirect.com/science/article/pii/S2211124725001688
Feb 2025
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Inositol polyphosphate multikinase regulates Th1 and Th17 cell differentiation by controlling Akt-mTOR signaling

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1. scibot 13 Feb 2025
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.celrep.2025.115281
  
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sciencedirect.com/science/article/pii/S221112472500052X
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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.014
  
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sciencedirect.com/science/article/pii/S1534580725000346
Jan 2025
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Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring

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1. scibot 16 Jan 2025
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.cmet.2024.12.002
  
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sciencedirect.com/science/article/pii/S1550413124004844
Dec 2024
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Activation of Bradykinin B2 Receptors in Astrocytes Stimulates the Release of Leukemia Inhibitory Factor for Autocrine and Paracrine Signaling

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1. scibot 22 Dec 2024
  
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  RRID:AB_331586
  
  DOI: 10.3390/ijms252313079
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11642044/
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Pancreatic β cell interleukin-22 receptor subunit alpha 1 deficiency impairs β cell function in type 2 diabetes via cytochrome b5 reductase 3

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1. scibot 17 Dec 2024
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.celrep.2024.115057
  
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sciencedirect.com/science/article/pii/S2211124724014086
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Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

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1. scibot 10 Dec 2024
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.immuni.2024.11.008
  
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sciencedirect.com/science/article/pii/S1074761324005235
Oct 2024
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Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment

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1. scibot 02 Oct 2024
  
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  RRID:AB_331586
  
  DOI: 10.1158/0008-5472.CAN-23-3553
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405138/
Sep 2024
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Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution

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1. scibot 25 Sep 2024
  
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  RRID:AB_2331586
  
  DOI: 10.1016/j.celrep.2020.108670
  
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  Curator comments: Phospho-Stat-3 (tyr705) antibody Cell Signaling Technology Cat# 9131
  
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sciencedirect.com/science/article/pii/S2211124720316594
Aug 2024
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Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114616
  
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sciencedirect.com/science/article/pii/S2211124724009665
Jul 2024
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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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1. scibot 24 Jul 2024
  
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  DOI: 10.1016/j.celrep.2021.109363
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8328392/
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Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts

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1. scibot 19 Jul 2024
  
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  AB_331586
  
  DOI: 10.1016/j.isci.2024.110415
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11295714/
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Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice

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1. scibot 18 Jul 2024
  
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  DOI: 10.7554/eLife.93204
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11249761/
Apr 2024
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Anorexia-Induced Hypoleptinemia Drives Adaptations in the JAK2/STAT3 Pathway in the Ventral and Dorsal Hippocampus of Female Rats

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1. scibot 30 Apr 2024
  
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  DOI: 10.3390/nu16081171
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11054075/
Feb 2024
52.53.155.43 52.53.155.43

can-22-3965-html.html

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1. scibot 23 Feb 2024
  
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  DOI: 10.1158/0008-5472.can-22-3965
  
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52.53.155.43/b267fbdd19a530509c54979d05951e91bb2c0d21/3693-html.html
Jan 2024
dx.doi.org dx.doi.org

Crosstalk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem Cells

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1. scibot 25 Jan 2024
  
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  DOI: 10.1158/0008-5472.CAN-22-3965
  
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dx.doi.org/10.1158/0008-5472.CAN-22-3965
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miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.

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1. scibot 18 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108650
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
Dec 2023
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A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling

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1. scibot 21 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108568
  
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sciencedirect.com/science/article/pii/S2589004223026457
Nov 2023
52.53.155.43 52.53.155.43

can-22-3965-html.html

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1. scibot 10 Nov 2023
  
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  DOI: 10.1158/0008-5472.can-22-3965
  
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52.53.155.43/b267fbdd19a530509c54979d05951e91bb2c0d21/3693-html.html
Oct 2023
52.53.155.43 52.53.155.43

can-22-3965-html.html

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1. scibot 07 Oct 2023
  
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  RRID:AB_331586
  
  DOI: 10.1158/0008-5472.can-22-3965
  
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52.53.155.43/b267fbdd19a530509c54979d05951e91bb2c0d21/3693-html.html
Sep 2023
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AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages

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1. scibot 07 Sep 2023
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.celrep.2023.113067
  
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sciencedirect.com/science/article/pii/S2211124723010781
Aug 2023
52.53.155.43 52.53.155.43

ASCL1 is activated downstream of the ROR2/CREB signaling pathway to support lineage plasticity in prostate cancer

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112937
  
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2. scibot 10 Aug 2023
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.celrep.2023.112937
  
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52.53.155.43/5c44b570825d260ed49e3beddaa9d47779a57883/PIIS2211124723009488-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages

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1. scibot 16 Aug 2023
  
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  RRID:AB_331586
  
  DOI: 10.1016/j.isci.2023.107473
  
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Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase

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British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html

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Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21

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N-arachidonylglycine is a caloric state-dependent circulating metabolite which regulates human CD4+ T cell responsiveness.

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Decoding the molecular crosstalk between grafted stem cells and the stroke-injured brain

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

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Activation of PDGF signaling in the adult muscle stem cell niche in patients with type 2 diabetes mellitus

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Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

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BPS Publications

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Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity

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Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation

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EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma

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Characterization of the metabolic differences between male and female C57BL/6 mice

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Translational Strategies for Repotrectinib in Neuroblastoma

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Interleukin-6 trans-signaling promotes progesterone production in human granulosa-lutein cells

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Leptin brain entry via a tanycytic LepR–EGFR shuttle controls lipid metabolism and pancreas function

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Female-specific role of ciliary neurotrophic factor in the medial amygdala in promoting stress responses

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Activating JAK-mutations confer resistance to FLT3 kinase inhibitors in FLT3-ITD positive AML in vitro and in vivo

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Leptin coordinates efferent sympathetic outflow to the white adipose tissue through the midbrain centrally-projecting Edinger-Westphal nucleus in male rats

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Anthelmintic niclosamide attenuates pressure-overload induced heart failure in mice

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Converging purinergic and immune signaling pathways drive IL-6 secretion by Fragile X cortical astrocytes via STAT3

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Leptin receptor expression in GABAergic cells is not sufficient to normalize metabolism and reproduction in mice

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IL6/sIL-6Rα trans-signaling increases PGE2 production in human granulosa cells

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GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK

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Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft.

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Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPKα Signaling in Male Offspring of Obese Dams

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The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

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Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer

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Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death

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Treatment of type 2 diabetes with the designer cytokine IC7Fc

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POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

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A Critical Period for the Trophic Actions of Leptin on AgRP Neurons in the Arcuate Nucleus of the Hypothalamus

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Modulation of Akt vs Stat3 activity by the focal adhesion kinase in non-neoplastic mouse fibroblasts

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

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Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin

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The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent mechanism

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Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells

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Fasting reduces the number of TRH immunoreactive neurons in the hypothalamic paraventricular nucleus of male rats, but not in mice

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Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer

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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis

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The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design

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Capturing human trophoblast development with naive pluripotent stem cells in vitro

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Cell autonomous angiotensin II signaling controls the pleiotropic functions of oncogenic K-Ras

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Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis

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Central growth hormone action regulates metabolism during pregnancy

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The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching

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Glucocorticoids attenuate interleukin‐6‐induced c‐Fos and Egr1 expression and impair neuritogenesis in PC12 cells

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Leptin suppresses development of GLP-1 inputs to the paraventricular nucleus of the hypothalamus

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A Leptin-Mediated Neural Mechanism Linking Breathing to Metabolism

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Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

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Differences between rats and mice in the leptin action on the paraventricular nucleus of the hypothalamus: implications for the regulation of the hypothalamic‐pituitary‐thyroid axis

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Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription

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Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes

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Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients

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Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1

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A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies

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Sugar causes obesity and metabolic syndrome in mice independently of sweet taste | American Journal of Physiology-Endocrinology and Metabolism

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Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia

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Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells

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Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis

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Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy

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Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling

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Luciferase Reporter Mice for In Vivo Monitoring and Ex Vivo Assessment of Hypothalamic Signaling of Socs3 Expression

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  DOI: 10.1210/js.2019-00077
  
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A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism

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Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression

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Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

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The antiviral cytokine interferon‐gamma restricts neural stem/progenitor cell proliferation through activation of STAT1 and modulation of retinoblastoma protein phosphorylation

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Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

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Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression

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Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

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Epigenetic Promoter DNA Methylation of miR-124 Promotes HIV-1 Tat-Mediated Microglial Activation via MECP2-STAT3 Axis

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Preoptic leptin signaling modulates energy balance independent of body temperature regulation

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Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses

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Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord

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IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure

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The Hypothalamic Inflammatory/Gliosis Response to Neonatal Overnutrition Is Sex and Age Dependent

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Calmodulin‐like skin protein protects against spatial learning impairment in a mouse model of Alzheimer disease

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Untitled document

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Dynamics of Gut-Brain Communication Underlying Hunger

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Corticosterone primes the neuroinflammatory response to Gulf War Illness‐relevant organophosphates independently of acetylcholinesterase inhibition

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Decrease in Expression of HOXA10 in the Decidua After Embryo Implantation Promotes Trophoblast Invasion

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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

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Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma

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Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility

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MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation

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PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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