154 Matching Annotations
  1. Jul 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NOD1 promotes leukocyte clearance and limits inflammation in female mice during obesity‐associated acute lung injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227658/
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    The immune response against cancer is modulated by stromal cell fibronectin
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    sciencedirect.com/science/article/pii/S1476558625000764
  4. Jun 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct cAMP Regulation in Scleroderma Lung and Skin Myofibroblasts Governs Their Dedifferentiation via p38α Inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC12186599/
  6. link.springer.com link.springer.com
    RNA polymerase II subunit 5-mediating protein limits TLR4-induced innate immune activation in macrophages by inhibiting IKKβ/NF-κB signaling during sepsis
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    link.springer.com/article/10.1186/s12964-025-02278-w
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130807/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12116916/
  9. Apr 2025
  10. www.embopress.org www.embopress.org
    TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation
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    embopress.org/doi/10.1038/s44319-025-00444-2
  11. www.sciencedirect.com www.sciencedirect.com
    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124725003122
  12. Mar 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism
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    pmc.ncbi.nlm.nih.gov/articles/PMC11940610/
  14. Feb 2025
  15. 52.53.155.43 52.53.155.43
    Mitochondrial Transplantation: Adaptive Bio-enhancement
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    52.53.155.43/85601644e55cec07aadbc955965cdaf3b280aaf3/2024.09.20.614058v2.full-html.html
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225002160-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11904601/
  17. Jan 2025
  18. www.sciencedirect.com www.sciencedirect.com
    Calcineurin: An essential regulator of sleep revealed by biochemical, chemical biological, and genetic approaches
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    sciencedirect.com/science/article/pii/S2451945624005130
  19. Dec 2024
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Activation of Bradykinin B2 Receptors in Astrocytes Stimulates the Release of Leukemia Inhibitory Factor for Autocrine and Paracrine Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642044/
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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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    sciencedirect.com/science/article/pii/S2211124724014554
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    Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
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    sciencedirect.com/science/article/pii/S1931312824004384
  23. www.sciencedirect.com www.sciencedirect.com
    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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    sciencedirect.com/science/article/pii/S2211124724013354
  24. Sep 2024
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy
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    onlinelibrary.wiley.com/doi/10.1002/glia.24612
  26. Aug 2024
  27. pubs.rsc.org pubs.rsc.org
    Hexane Insoluble Fraction from Purple Rice Extract Improves Steatohepatitis and Fibrosis via Inhibition of NF-κB and JNK Signaling
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    pubs.rsc.org/en/content/articlelanding/2024/fo/d4fo00292j
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24119/full
  29. Jul 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11274253/
  31. www.sciencedirect.com www.sciencedirect.com
    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
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    sciencedirect.com/science/article/pii/S2451945624002745
  32. www.sciencedirect.com www.sciencedirect.com
    pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism
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    sciencedirect.com/science/article/pii/S1097276524004775
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    sciencedirect.com/science/article/pii/S2666379124003276
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
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    ncbi.nlm.nih.gov/pmc/articles/PMC10146492/
  35. May 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068553/
  37. Apr 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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    sciencedirect.com/science/article/pii/S209012322400119X
  39. Mar 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10916047/
  41. Feb 2024
  42. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    mdpi.com/1467-3045/45/12/620
  43. Jan 2024
  44. www.sciencedirect.com www.sciencedirect.com
    Maintaining Toll signaling in Drosophila brain is required to sustain autophagy for dopamine neuron survival
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    sciencedirect.com/science/article/pii/S2589004224000166
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SORCS2 activity in pancreatic α-cells safeguards insulin granule formation and release from glucose-stressed β-cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788290/
  46. Dec 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    sciencedirect.com/science/article/pii/S2211124723015723
  48. www.sciencedirect.com www.sciencedirect.com
    Single-cell analysis reveals a weak macrophage subpopulation response to Mycobacterium tuberculosis infection
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    sciencedirect.com/science/article/pii/S2211124723014304
  49. Oct 2023
  50. www.sciencedirect.com www.sciencedirect.com
    JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
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    sciencedirect.com/science/article/pii/S221112472301135X
  51. Sep 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC10012955/
  53. Jun 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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    sciencedirect.com/science/article/pii/S1074761323002315
  55. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
  56. May 2023
  57. 52.53.155.43 52.53.155.43
    PAC1 deficiency protects obese male mice from immobilization-induced muscle atrophy by suppressing FoxO-atrogene axis
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    52.53.155.43/bdf89ee8b17f684d89776b136763c0415969fc5a/RRID9-html.html
  58. www.sciencedirect.com www.sciencedirect.com
    VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
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    sciencedirect.com/science/article/pii/S2211124723005004
  59. www.mdpi.com www.mdpi.com
    Lysimachiae Herba Inhibits Inflammatory Reactions and Improves Lipopolysaccharide/D-Galactosamine-Induced Hepatic Injury
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    mdpi.com/2076-3921/10/9/1387/htm
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides
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    ncbi.nlm.nih.gov/pmc/articles/PMC10161466/
  61. Apr 2023
  62. www.embopress.org www.embopress.org
    RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis
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    embopress.org/doi/10.15252/emmm.202217078
  63. link.springer.com link.springer.com
    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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    link.springer.com/article/10.1186/s12935-023-02884-z
  64. Mar 2023
  65. www.sciencedirect.com www.sciencedirect.com
    FSBP suppresses tumor cell migration by inhibiting the JNK pathway
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    sciencedirect.com/science/article/pii/S2589004223005175
  66. www.sciencedirect.com www.sciencedirect.com
    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
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    sciencedirect.com/science/article/pii/S1550413123000827
  67. elifesciences.org elifesciences.org
    Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass
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    elifesciences.org/articles/82118
  68. Feb 2023
  69. www.sciencedirect.com www.sciencedirect.com
    CAR-T cells targeting HLA-G as potent therapeutic strategy for EGFR mutated and overexpressed oral cancer
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    sciencedirect.com/science/article/pii/S2589004223001669
  70. www.nature.com www.nature.com
    Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
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    nature.com/articles/s42003-023-04568-w
  71. journals.lww.com journals.lww.com
    Macrophage migration inhibitory factor facilitates... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/08000/Macrophage_migration_inhibitory_factor_facilitates.38.aspx
  72. Jan 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism
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    ncbi.nlm.nih.gov/pmc/articles/PMC9843443/
  74. www.sciencedirect.com www.sciencedirect.com
    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
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    sciencedirect.com/science/article/pii/S2211124722018654
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC9838143/
  76. 52.53.155.43 52.53.155.43
    SSRN-id4244248-html.html
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    52.53.155.43/96a427cfb48438f69f3a112411c029b6e1560929/SSRN-id4244248-html.html
  77. Dec 2022
  78. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    mdpi.com/2072-6643/14/24/5265
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations
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    ncbi.nlm.nih.gov/pmc/articles/PMC9709411/
  80. www.sciencedirect.com www.sciencedirect.com
    Neuronal IRE-1 coordinates an organism-wide cold stress response by regulating fat metabolism
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    sciencedirect.com/science/article/pii/S2211124722016175
  81. Nov 2022
  82. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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    mdpi.com/2073-4409/11/22/3665
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial prophylactic effect of phlorotannins with photobiomodulation against tracheal stenosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9664362/
  84. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
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    science.org/doi/10.1126/sciadv.abn9912
  85. www.science.org www.science.org
    An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
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    science.org/doi/10.1126/scisignal.abi8713
  86. www.researchsquare.com www.researchsquare.com
    Home
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    researchsquare.com/
  87. www.cell.com www.cell.com
    Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
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    cell.com/cell-reports/abstract/S2211-1247(22)01347-X
  88. Aug 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-inflammatory effects of neutral lipids, glycolipids, phospholipids from Halocynthia aurantium tunic by suppressing the activation of NF-κB and MAPKs in LPS-stimulated RAW264.7 macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377571/
  90. www.sciencedirect.com www.sciencedirect.com
    Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
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    sciencedirect.com/science/article/pii/S2211124722009809
  91. Jul 2022
  92. www.sciencedirect.com www.sciencedirect.com
    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2451945622002458
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manipulating bovine granulosa cell energy metabolism limits inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9272410/
  94. www.sciencedirect.com www.sciencedirect.com
    Melatonin attenuates manganese-induced mitochondrial fragmentation by suppressing the Mst1/JNK signaling pathway in primary mouse neurons
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    sciencedirect.com/science/article/pii/S0048969722042310
  95. www.sciencedirect.com www.sciencedirect.com
    Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons
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    sciencedirect.com/science/article/pii/S0969996122002005
  96. Jun 2022
  97. www.sciencedirect.com www.sciencedirect.com
    Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice
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    sciencedirect.com/science/article/pii/S2211124722007215
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Undercarboxylated, but not Carboxylated, Osteocalcin suppresses TNF-α induced inflammatory signaling pathway in Myoblast
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    ncbi.nlm.nih.gov/pmc/articles/PMC9188654/
  99. May 2022
  100. link.springer.com link.springer.com
    Cdk5-mediated JIP1 phosphorylation regulates axonal outgrowth through Notch1 inhibition
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    link.springer.com/article/10.1186/s12915-022-01312-4
  101. Apr 2022
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control
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    ncbi.nlm.nih.gov/pmc/articles/PMC8957965/
  103. Mar 2022
  104. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    sciencedirect.com/science/article/pii/S2211124722000705
  105. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15758
  106. Feb 2022
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins
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    ncbi.nlm.nih.gov/pmc/articles/PMC8825411/
  108. www.sciencedirect.com www.sciencedirect.com
    Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants
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    sciencedirect.com/science/article/pii/S2589004222000803
  109. Jan 2022
  110. ar.iiarjournals.org ar.iiarjournals.org
    The Thioredoxin Reductase Inhibitor Auranofin Suppresses Pulmonary Metastasis of Osteosarcoma, But Not Local Progression
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    ar.iiarjournals.org/content/41/10/4947
  111. www.sciencedirect.com www.sciencedirect.com
    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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    sciencedirect.com/science/article/pii/S0753332222000038
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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    ncbi.nlm.nih.gov/pmc/articles/PMC8700290/
  113. Dec 2021
  114. link.springer.com link.springer.com
    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    link.springer.com/article/10.1007/s10863-018-9750-3
  115. Nov 2021
  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15695
  117. Oct 2021
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8524153/
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs
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    ncbi.nlm.nih.gov/pmc/articles/PMC8545060/
  120. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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