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Iron drives protease-independent cleavage of gasdermin D in allergic airway diseases

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1. scibot 27 Jun 2026
  
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  DOI: 10.1016/j.cell.2026.06.004
  
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sciencedirect.com/science/article/pii/S0092867426006537
May 2026
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Mechanism by which a linoleic acid metabolite suppresses cancer cell growth by inhibiting mTOR

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.chembiol.2026.04.004
  
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sciencedirect.com/science/article/pii/S2451945626001376
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis

1
1. scibot 09 Apr 2026
  
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  DOI: 10.1158/2159-8290.CD-25-1126
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13056290/
Dec 2025
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Mitochondrial VHL rewires cell metabolism in hypoxia

1
1. scibot 23 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.11.013
  
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sciencedirect.com:5037/science/article/pii/S1550413125005273
Nov 2025
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PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer

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1. scibot 23 Nov 2025
  
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  DOI: 10.1261/rna.080637.125
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12530129/
Aug 2025
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AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

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1. scibot 13 Aug 2025
  
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  DOI: 10.1126/sciadv.adv2453
  
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science.org/doi/10.1126/sciadv.adv2453
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AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

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1. scibot 12 Aug 2025
  
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  DOI: 10.1126/sciadv.adv2453
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12327453/
Jun 2025
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PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer

1
1. scibot 24 Jun 2025
  
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  DOI: 10.1016/j.jbc.2025.110406
  
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sciencedirect.com/science/article/pii/S0021925825022562
Feb 2024
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Ethylene-MPK8-ERF.C1-PR module confers resistance against Botrytis cinerea in tomato fruit without compromising ripening

1
1. scibot 27 Feb 2024
  
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  DOI: 10.1111/nph.19632
  
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nph.onlinelibrary.wiley.com/doi/10.1111/nph.19632
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UDP-glucose dehydrogenase supports autophagy-deficient PDAC growth via increasing hyaluronic acid biosynthesis

1
1. scibot 24 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113808
  
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sciencedirect.com/science/article/pii/S2211124724001360
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Axon-derived PACSIN1 binds to the Schwann cell survival receptor, LRP1, and transactivates TrkC to promote gliatrophic activities

1
1. scibot 22 Feb 2024
  
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  AB_331670
  
  DOI: 10.1002/glia.24510
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24510
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TRPM2 enhances ischemic excitotoxicity by associating with PKCγ

1
1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113722
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11023021/
Sep 2023
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A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants

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1. scibot 14 Sep 2023
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2023.113104
  
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sciencedirect.com/science/article/pii/S2211124723011154
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Deciphering the functional landscape of phosphosites with deep neural network

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1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113048
  
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sciencedirect.com/science/article/pii/S2211124723010598
Apr 2023
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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112314
  
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sciencedirect.com/science/article/pii/S221112472300325X
Jan 2023
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Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112041
  
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sciencedirect.com/science/article/pii/S2211124723000529
Oct 2022
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OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis

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1. scibot 26 Oct 2022
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2022.111561
  
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sciencedirect.com/science/article/pii/S221112472201422X
Sep 2022
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Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization

1
1. scibot 22 Sep 2022
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2022.111361
  
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sciencedirect.com/science/article/pii/S2211124722011937
Jun 2022
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Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease

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1. scibot 02 Jun 2022
  
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  DOI: 10.1016/j.neuron.2022.05.009
  
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sciencedirect.com/science/article/pii/S0896627322004500
Mar 2022
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Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

1
1. scibot 02 Mar 2022
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.molcel.2022.02.005
  
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sciencedirect.com/science/article/pii/S1097276522001101
Feb 2022
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HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia

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1. scibot 18 Feb 2022
  
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  DOI: 10.1016/j.molcel.2022.01.014
  
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sciencedirect.com/science/article/pii/S1097276522000570
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Tethering Piezo channels to the actin cytoskeleton for mechanogating via the cadherin-β-catenin mechanotransduction complex

2
1. scibot 11 Feb 2022
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2022.110342
  
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2. scibot 09 Feb 2022
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2022.110342
  
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sciencedirect.com/science/article/pii/S2211124722000584
Sep 2021
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The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

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1. scibot 23 Sep 2021
  
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  RRID: AB_331670
  
  DOI: 10.1016/j.molcel.2021.08.033
  
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sciencedirect.com/science/article/pii/S1097276521007139
Jul 2021
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IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration

1
1. scibot 31 Jul 2021
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2019.02.013
  
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sciencedirect.com/science/article/pii/S2211124719301755
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CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

1
1. scibot 08 Jul 2021
  
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  RRID:AB_331670
  
  DOI: 10.1083/jcb.202012114
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8236918/
Nov 2020
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Structural Basis of CYRI-B Direct Competition with Scar/WAVE Complex for Rac1

1
1. scibot 28 Nov 2020
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.str.2020.11.003
  
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sciencedirect.com/science/article/pii/S0969212620304159
Jan 2020
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Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.molcel.2019.07.018
  
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sciencedirect.com/science/article/pii/S1097276519305489
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Su(var)2-10 and the SUMO Pathway Link piRNA-Guided Target Recognition to Chromatin Silencing

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.molcel.2019.11.012
  
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sciencedirect.com/science/article/pii/S109727651930841X
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Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.10.117
  
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sciencedirect.com/science/article/pii/S2211124719314500
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OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.cmet.2019.05.022
  
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sciencedirect.com/science/article/pii/S1550413119302621
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IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331670
  
  DOI: 10.1016/j.celrep.2019.02.013
  
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sciencedirect.com/science/article/pii/S2211124719301755
Nov 2018
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Vitamin D Switches BAF Complexes to Protect β Cells

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867418305063
Nov 2017
www.jneurosci.org www.jneurosci.org

Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion

1
1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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jneurosci.org/content/37/23/5620
elifesciences.org elifesciences.org

Registered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

1
1. scibot 08 Nov 2017
  
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  Rabbit anti-GST
  
  Curator: @jcabotaj
  
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elifesciences.org/content/5/e09976