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    Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells
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    sciencedirect.com/science/article/pii/S1097276524006191
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    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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  4. Aug 2024
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    Sestrin2 drives ER-phagy in response to protein misfolding
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    Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice
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    EDC3 phosphorylation regulates growth and invasion through controlling P‐body formation and dynamics
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  8. Jul 2024
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    Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles
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  10. Jun 2024
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    Electron transport chain inhibition increases cellular dependence on purine transport and salvage
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    Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency
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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  14. May 2024
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    Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
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    SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis
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  17. 52.53.155.43 52.53.155.43
    2024.02.09.579580v1.full-html.html
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    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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  20. Apr 2024
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    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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    The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle
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    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
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  26. Feb 2024
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    Molecular mechanism of S-adenosylmethionine sensing by SAMTOR in mTORC1 signaling
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    Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells
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    MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension
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  31. Dec 2023
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    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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  33. Nov 2023
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk
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    PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemia
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  37. Oct 2023
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    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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  39. Sep 2023
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    Underpinning the food matrix regulation of post-exercise myofibrillar protein synthesis by comparing salmon ingestion versus the sum of its isolated nutrients in healthy young adults
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    Aggravated hepatic fibrosis induced by phenylalanine and tyrosine was ameliorated by chitooligosaccharides supplementation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10507131/
  42. Aug 2023
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    Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
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  44. Jul 2023
  45. dx.doi.org dx.doi.org
    Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis
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      DOI: 10.1158/1535-7163.MCT-22-0224

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    Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
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  47. 52.53.155.43 52.53.155.43
    mct-22-0224 (1)-html.html
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  48. Jun 2023
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    Bursting translation on single mRNAs in live cells
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    sciencedirect.com/science/article/pii/S1097276523003751
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    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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    Fasting produces antidepressant-like effects via activating mammalian target of rapamycin complex 1 signaling pathway in ovariectomized mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10233788/
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    PICT-1 regulates p53 splicing and sensitivity of medullary thyroid carcinoma cells to Everolimus
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      DOI: 10.1111/jne.13187

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  53. www.jneurosci.org www.jneurosci.org
    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
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      DOI: 10.1523/JNEUROSCI.0146-23.2023

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  54. May 2023
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    N-arachidonylglycine is a caloric state-dependent circulating metabolite which regulates human CD4+ T cell responsiveness.
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  124. Oct 2021
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    Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity
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    Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
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    Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis
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  151. May 2021
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    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
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    Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis
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    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    eEF2/eEF2K Pathway in the Mature Dentate Gyrus Determines Neurogenesis Level and Cognition
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    A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes
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    Very-low-protein diets lead to reduced food intake and weight loss, linked to inhibition of hypothalamic mTOR signaling, in mice
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    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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  169. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Reduced Na+K+‐ATPase activity may reduce amino acid uptake in IUGR fetal sheep muscle despite unchanged ex vivo amino acid transporter activity
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  170. Jan 2021
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    Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma
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  172. Nov 2020
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    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
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    Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
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  176. Oct 2020
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    Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
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    The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest
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  180. Sep 2020
  181. elifesciences.org elifesciences.org
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    Enhancer-Driven lncRNA BDNF-AS Induces Endocrine Resistance and Malignant Progression of Breast Cancer through the RNH1/TRIM21/mTOR Cascade
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    The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis
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    Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms
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    Aster‐C coordinates with COP I vesicles to regulate lysosomal trafficking and activation of mTORC1
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    IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
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      rabbit anti-p70 S6 kinase

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    Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
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    Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1
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  197. Aug 2020
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    Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
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  199. Jan 2020
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    Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity
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    CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways
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    Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
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    A Split-Abl Kinase for Direct Activation in Cells
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    Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism
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    eIF4A inactivates TORC1 in response to amino acid starvation
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    L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
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