104 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    1. scibot 13 Dec 2024
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      DOI: 10.1038/s44321-024-00161-8

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    pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
  3. www.sciencedirect.com www.sciencedirect.com
    Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.immuni.2024.11.005

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    sciencedirect.com/science/article/pii/S107476132400520X
  4. Sep 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells
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    1. scibot 27 Sep 2024
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      DOI: 10.1111/jnc.16210

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16210
  6. www.sciencedirect.com www.sciencedirect.com
    Zdhhc1- and Zdhhc2-mediated Gpm6a palmitoylation is essential for maintenance of mammary stem cell activity
    1
    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S2211124724011136
  7. www.nature.com www.nature.com
    Defective N-glycosylation of IL6 induces metastasis and tyrosine kinase inhibitor resistance in lung cancer
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    1. scibot 13 Sep 2024
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      DOI: 10.1038/s41467-024-51831-7

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    nature.com/articles/s41467-024-51831-7
  8. Aug 2024
  9. www.cell.com www.cell.com
    Calcineurin is an adaptor required for assembly of the TCR signaling complex
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    1. scibot 18 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114568

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    cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
  10. www.biorxiv.org www.biorxiv.org
    Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
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    1. scibot 18 Aug 2024
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      DOI: 10.1101/2024.07.31.605623

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    biorxiv.org/content/10.1101/2024.07.31.605623v1
  11. Jul 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Paradoxical activation of c-Src as a drug-resistant mechanism
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    1. scibot 10 Jul 2024
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      DOI: 10.1016/j.celrep.2021.108876

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    2. scibot 10 Jul 2024
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      DOI: 10.1016/j.celrep.2021.108876

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    sciencedirect.com/science/article/pii/S221112472100190X
  13. Jun 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p38 MAPK activation and STIM1-Orai3 association mediate TRPC6 externalization
    1
    1. scibot 07 Jun 2024
      RRID:AB_331697

      DOI: 10.1152/ajpcell.00425.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10228675/
  15. Mar 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
    2
    1. scibot 13 Mar 2024
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    sciencedirect.com/science/article/pii/S1074761324000906
  17. Feb 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ibrutinib-induced pulmonary angiotensin-converting enzyme activation promotes atrial fibrillation in rats
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.isci.2024.108926

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    ncbi.nlm.nih.gov/pmc/articles/PMC10864204/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
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      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  20. Dec 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol to characterize extracellular c-Src tyrosine kinase function through substrate interaction and phosphorylation
    1
    1. scibot 10 Dec 2023
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      DOI: 10.1016/j.xpro.2023.102755

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    ncbi.nlm.nih.gov/pmc/articles/PMC10701435/
  22. Nov 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113361

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    sciencedirect.com/science/article/pii/S2211124723013736
  24. Aug 2023
  25. 52.53.155.43 52.53.155.43
    Adamtsl3 mediates DCC signaling to selectively promote GABAergic synapse function
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112947

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    52.53.155.43/1ebffb0e500c938d4759cf06bd212c5ef05c3aed/PIIS2211124723009580-html.html
  26. Jul 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase
    1
    1. scibot 25 Jul 2023
      RRID:AB_331697

      DOI: 10.7554/eLife.82428

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    ncbi.nlm.nih.gov/pmc/articles/PMC10361714/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A back-door insight into the modulation of Src kinase activity by the polyamine spermidine
    1
    1. scibot 12 Jul 2023
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      DOI: 10.7554/eLife.85872

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    ncbi.nlm.nih.gov/pmc/articles/PMC10328509/
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.celrep.2023.112539

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    sciencedirect.com/science/article/pii/S2211124723005508
  31. www.sciencedirect.com www.sciencedirect.com
    Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.cmet.2023.04.017

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    sciencedirect.com/science/article/pii/S1550413123001717
  32. Mar 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
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    1. scibot 02 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112164

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    sciencedirect.com/science/article/pii/S2211124723001754
  34. Feb 2023
  35. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
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      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  36. Dec 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α5 integrin regulates hepatic tight junctions through SRC-TET1-mediated DNA hydroxymethylation
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    1. scibot 02 Dec 2022
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      DOI: 10.1016/j.isci.2022.105611

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    ncbi.nlm.nih.gov/pmc/articles/PMC9709229/
  38. Nov 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation
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    1. scibot 24 Nov 2022
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      DOI: 10.1016/j.mcn.2022.103794

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    sciencedirect.com/science/article/pii/S1044743122001002
  40. www.sciencedirect.com www.sciencedirect.com
    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
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    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.isci.2022.105184

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    sciencedirect.com/science/article/pii/S2589004222014560
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Niraparib-induced STAT3 inhibition increases its antitumor effects
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    1. scibot 04 Nov 2022
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      DOI: 10.3389/fonc.2022.966492

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    ncbi.nlm.nih.gov/pmc/articles/PMC9618811/
  42. Oct 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function
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      DOI: 10.1016/j.isci.2022.105171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9530850/
  44. Sep 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma
    1
    1. scibot 21 Sep 2022
      RRID:mAb#2101

      DOI: 10.1016/j.xcrm.2022.100659

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    sciencedirect.com/science/article/pii/S2666379122001914
  46. Aug 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches
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      DOI: 10.3390/cancers14153726

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    ncbi.nlm.nih.gov/pmc/articles/PMC9367554/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration
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      DOI: 10.3390/cells11152343

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    ncbi.nlm.nih.gov/pmc/articles/PMC9367513/
  49. Jul 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude
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      DOI: 10.1016/j.celrep.2022.111080

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    sciencedirect.com/science/article/pii/S2211124722008786
  51. May 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Strategies for Repotrectinib in Neuroblastoma
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      DOI: 10.1158/1535-7163.MCT-21-0126

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    ncbi.nlm.nih.gov/pmc/articles/PMC8571000/
  53. Apr 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HO-1 Upregulation by Kaempferol via ROS-Dependent Nrf2-ARE Cascade Attenuates Lipopolysaccharide-Mediated Intercellular Cell Adhesion Molecule-1 Expression in Human Pulmonary Alveolar Epithelial Cells
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      DOI: 10.3390/antiox11040782

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    ncbi.nlm.nih.gov/pmc/articles/PMC9028455/
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    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
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      DOI: 10.1016/j.chembiol.2022.03.010

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    sciencedirect.com/science/article/pii/S2451945622001271
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis
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      DOI: 10.1016/j.isci.2022.104123

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    ncbi.nlm.nih.gov/pmc/articles/PMC8987407/
  57. Mar 2022
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice
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      DOI: 10.1002/glia.23583

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    onlinelibrary.wiley.com/doi/10.1002/glia.23583
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    Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells
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      DOI: 10.1016/j.celrep.2022.110548

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    sciencedirect.com/science/article/pii/S2211124722002893
  60. www.sciencedirect.com www.sciencedirect.com
    Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus
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      DOI: 10.1016/j.ebiom.2022.103903

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    sciencedirect.com/science/article/pii/S2352396422000871
  61. Feb 2022
  62. link.springer.com link.springer.com
    Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis
    1
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      RRID:AB_331697

      DOI: 10.1007/s10456-022-09831-y

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  63. Jan 2022
  64. www.sciencedirect.com www.sciencedirect.com
    GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
    1
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      RRID:AB_331697

      DOI: 10.1016/j.cell.2021.12.024

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    sciencedirect.com/science/article/pii/S0092867421014872
  65. Dec 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EGFR transactivates RON to drive oncogenic crosstalk
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      RRID:AB_331697

      DOI: 10.7554/eLife.63678

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    ncbi.nlm.nih.gov/pmc/articles/PMC8654365/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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      DOI: 10.1158/1535-7163.MCT-20-0640

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  68. Nov 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
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      DOI: 10.1016/j.celrep.2021.110036

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  70. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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  71. www.sciencedirect.com www.sciencedirect.com
    TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
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  72. Oct 2021
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1
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      DOI: 10.1016/j.isci.2021.103189

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8516413/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity
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  76. Sep 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
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      DOI: 10.1016/j.cmet.2021.09.003

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  78. www.sciencedirect.com www.sciencedirect.com
    Senescent immune cells release grancalcin to promote skeletal aging
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  79. Aug 2021
  80. www.mdpi.com www.mdpi.com
    Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC
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      DOI: 10.3390/ijms20102423

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  81. Jul 2021
  82. www.frontiersin.org www.frontiersin.org
    Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs
    1
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      P-Src

      DOI: 10.3389/fncel.2019.00324

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  83. www.sciencedirect.com www.sciencedirect.com
    Allosteric activation of T cell antigen receptor signaling by quaternary structure relaxation
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  84. May 2021
  85. www.sciencedirect.com www.sciencedirect.com
    VEGF counteracts amyloid-β-induced synaptic dysfunction
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    1. scibot 12 May 2021
      RRID:AB_331697

      DOI: 10.1016/j.celrep.2021.109121

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  86. Apr 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation
    1
    1. scibot 28 Apr 2021
      RRID:AB_331697

      DOI: 10.1016/j.chembiol.2021.02.019

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  88. www.sciencedirect.com www.sciencedirect.com
    Parallel Chemoselective Profiling for Mapping Protein Structure
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  89. www.jneurosci.org www.jneurosci.org
    NOX1/NADPH oxidase promotes synaptic facilitation induced by repeated D2 receptor stimulation; involvement in behavioral repetition
    1
    1. scibot 08 Apr 2021
      rabbit anti-phospho Src family

      DOI: 10.1523/JNEUROSCI.2121-20.2021

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    jneurosci.org/content/41/12/2780
  90. Mar 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Paradoxical activation of c-Src as a drug-resistant mechanism
    1
    1. scibot 24 Mar 2021
      RRID:AB_331697

      DOI: 10.1016/j.celrep.2021.108876

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    sciencedirect.com/science/article/pii/S221112472100190X
  92. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
    1
    1. scibot 03 Mar 2021
      rabbit polyclonal anti‐phospho‐Src

      DOI: 10.1096/fj.202001909R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001909R
  93. Feb 2021
  94. www.cell.com www.cell.com
    Rescue of Transgenic Alzheimer’s Pathophysiology by Polymeric Cellular Prion Protein Antagonists
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      RRID:AB_331697

      DOI: 10.1016/j.celrep.2018.12.021

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    cell.com/cell-reports/abstract/S2211-1247(18)31932-6
  95. link.springer.com link.springer.com
    Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide
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      DOI: 10.1007/s10719-020-09919-x

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  96. biosignaling.biomedcentral.com biosignaling.biomedcentral.com
    L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness
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      RRID:AB_331697

      DOI: 10.1186/s12964-021-00710-5

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    biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
  97. academic.oup.com academic.oup.com
    Leptin controls glutamatergic synaptogenesis and NMDA-receptor trafficking via Fyn kinase regulation of NR2B
    1
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      RRID:AB_331697

      DOI: 10.1210/endocr/bqz030

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    academic.oup.com/endo/article/161/2/bqz030/5678106
  98. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
    1
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      RRID:AB_331697

      DOI: 10.1016/j.celrep.2020.01.008

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    cell.com/cell-reports/abstract/S2211-1247(20)30017-6
  99. Dec 2020
  100. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Staphylococcus aureus Panton‐Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria
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    1. scibot 07 Dec 2020
      RRID:AB_331697

      DOI: 10.1096/fj.201902981R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201902981R
  101. Nov 2020
  102. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
    1
    1. scibot 07 Nov 2020
      anti-phospho-Src

      DOI: 10.1016/j.celrep.2020.108332

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  103. Oct 2020
  104. www.cell.com www.cell.com
    Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
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      RRID:AB_331697

      DOI: 10.1016/j.devcel.2020.05.031

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    cell.com/developmental-cell/abstract/S1534-5807(20)30420-2
  105. Sep 2020
  106. www.sciencedirect.com www.sciencedirect.com
    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
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      RRID:AB_331697

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst
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      RRID:AB_331697

      DOI: 10.7554/eLife.56656

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  108. www.cell.com www.cell.com
    Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells
    1
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      RRID:AB_331697

      DOI: 10.1016/j.celrep.2020.01.008

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  109. www.sciencedirect.com www.sciencedirect.com
    Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac
    1
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      RRID:AB_331697

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  110. www.sciencedirect.com www.sciencedirect.com
    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
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      RRID:AB_331697

      DOI: 10.1016/j.bcp.2020.113949

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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly
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      RRID:AB_331697

      DOI: 10.1242/dev.185405

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  112. link.springer.com link.springer.com
    mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington’s disease
    1
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      anti-Src

      DOI: 10.1186/s13041-020-00657-7

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  113. Jan 2020
  114. elifesciences.org elifesciences.org
    Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
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      RRID:AB_331697

      DOI: 10.7554/eLife.46043

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  115. www.sciencedirect.com www.sciencedirect.com
    HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry
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    1. scibot 13 Jan 2020
      RRID:AB_331697

      DOI: 10.1016/j.celrep.2019.02.095

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    sciencedirect.com/science/article/pii/S2211124719302815
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn‐independent effect of tau on calcium
    1
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      RRID:AB_331697

      DOI: 10.1002/jnr.24517

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    Astrocyte truncated tropomyosin receptor kinase B mediates brain‐derived neurotrophic factor anti‐apoptotic effect leading to neuroprotection
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    Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation
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    Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
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    Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)
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