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Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.ccell.2026.03.020
  
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sciencedirect.com/science/article/pii/S1535610826001741
Apr 2026
54.241.53.176 54.241.53.176

mct-25-0082-html.html

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1. scibot 12 Apr 2026
  
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  DOI: 10.1158/1535-7163.MCT-25-0082
  
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54.241.53.176/2c8ddc0e27a76adb2f23b3475d04f2bfaf812e65/mct-25-0082-html.html
Feb 2026
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Effects of N361 Glycosylation on Epidermal Growth Factor Receptor Biological Function

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1. scibot 14 Feb 2026
  
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  DOI: 10.3390/cancers18030474
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12896819/
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BCL-xL as a therapeutic target in cetuximab-refractory colorectal cancer

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1. scibot 10 Feb 2026
  
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  DOI: 10.1038/s41419-026-08434-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12876907/
May 2025
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Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

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1. scibot 20 May 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-2220
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
Dec 2024
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Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence

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1. scibot 11 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111311
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11617384/
Aug 2024
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The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes

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1. scibot 19 Aug 2024
  
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sciencedirect.com/science/article/pii/S2589004224017243
Jul 2024
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Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver

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1. scibot 19 Jul 2024
  
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cell.com/cell-reports/abstract/S2211-1247(24)00728-9
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HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice

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1. scibot 12 Jul 2024
  
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  DOI: 10.3390/ijms25137475
  
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mdpi.com/1422-0067/25/13/7475
Mar 2024
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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.023
  
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sciencedirect.com/science/article/pii/S0092867424002253
Feb 2024
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An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108794
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
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Functional Heterogeneity in MET Pathway Activation in PDX Models of Osimertinib Resistant EGFR-Driven Lung Cancer

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1. scibot 11 Feb 2024
  
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  DOI: 10.1158/2767-9764.CRC-23-0321
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10851855/
Oct 2023
52.53.155.43 52.53.155.43

bqad159-html.html

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1. scibot 31 Oct 2023
  
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  RRID:AB_331707
  
  DOI: 10.1210/endocr/bqad159
  
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52.53.155.43/fadb698104ccd541263e8069783171593188288f/bqad159-html.html
Aug 2023
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Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer

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1. scibot 27 Aug 2023
  
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  DOI: 10.1101/2023.08.21.554116
  
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biorxiv.org/content/10.1101/2023.08.21.554116v1
Feb 2023
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Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy

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1. scibot 11 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.106064
  
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sciencedirect.com/science/article/pii/S2589004223001414
Dec 2022
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KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition

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1. scibot 17 Dec 2022
  
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  DOI: 10.1016/j.ccell.2022.11.015
  
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sciencedirect.com/science/article/pii/S1535610822005621
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USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

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1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111653
  
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sciencedirect.com/science/article/pii/S2211124722015248
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Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma

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1. scibot 03 Dec 2022
  
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  DOI: 10.1158/2159-8290.CD-22-0287
  
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aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
Nov 2022
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RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

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1. scibot 10 Nov 2022
  
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  DOI: 10.1016/j.isci.2022.105184
  
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sciencedirect.com/science/article/pii/S2589004222014560
Jul 2022
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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.ccell.2022.06.006
  
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sciencedirect.com/science/article/pii/S1535610822002707
Jun 2022
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Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110991
  
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sciencedirect.com/science/article/pii/S221112472200777X
May 2022
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Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAF V600E mutant human glioma

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1. scibot 18 May 2022
  
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  DOI: 10.1158/1078-0432.CCR-21-2660
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8595717/
Jan 2022
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Tissue differences in the exosomal/small extracellular vesicle proteome and their potential as indicators of altered tissue metabolism

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1. scibot 19 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110277
  
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sciencedirect.com/science/article/pii/S2211124721017927
Dec 2021
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Substratum stiffness regulates Erk signaling dynamics through receptor-level control

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1. scibot 29 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110181
  
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sciencedirect.com/science/article/pii/S2211124721016818
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In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling

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1. scibot 02 Dec 2021
  
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  DOI: 10.1158/1535-7163.MCT-20-0640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
Nov 2021
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Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110054
  
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sciencedirect.com/science/article/pii/S2211124721015400
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AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells

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1. scibot 16 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103270
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
Jul 2021
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Untitled document

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1. scibot 27 Jul 2021
  
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  DOI: 10.7554/eLife.19671
  
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elifesciences.org/articles/19671
Jun 2021
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Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

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  DOI: 10.1016/j.ccell.2021.05.002
  
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sciencedirect.com/science/article/pii/S1535610821002683
May 2021
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UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

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1. scibot 19 May 2021
  
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  DOI: 10.7554/eLife.68348
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8118655/
Apr 2021
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NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation

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  DOI: 10.1016/j.celrep.2021.108949
  
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sciencedirect.com/science/article/pii/S2211124721002631
Feb 2021
biosignaling.biomedcentral.com biosignaling.biomedcentral.com

L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness

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1. scibot 25 Feb 2021
  
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  DOI: 10.1186/s12964-021-00710-5
  
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biosignaling.biomedcentral.com/articles/10.1186/s12964-021-00710-5
Nov 2020
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Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain

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1. scibot 20 Nov 2020
  
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  DOI: 10.1016/j.cmet.2020.09.011
  
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sciencedirect.com/science/article/pii/S1550413120304897
Sep 2020
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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.ccell.2019.12.006
  
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sciencedirect.com/science/article/pii/S1535610819305768
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Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling

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1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.014
  
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sciencedirect.com/science/article/pii/S2211124720301686
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Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis

1
1. scibot 15 Sep 2020
  
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  RRID:AB_331707
  
  DOI: 10.1016/j.cmet.2020.04.011
  
  Resource: (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1550413120301935
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Challenges and Reinterpretation of Antibody-Based Research on Phosphorylation of Tyr307 on PP2Ac

1
1. scibot 13 Sep 2020
  
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  RRID:AB_331707
  
  DOI: 10.1016/j.celrep.2020.02.012
  
  Resource: (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124720301662
Jan 2020
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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_331707
  
  DOI: 10.1016/j.ccell.2019.05.013
  
  Resource: (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1535610819302557
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LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_331707
  
  DOI: 10.1016/j.celrep.2019.11.063
  
  Resource: (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719315542
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_331707
  
  DOI: 10.1073/pnas.1805298115
  
  Resource: (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6196494/
Nov 2018
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COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331707
  
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sciencedirect.com/science/article/pii/S2211124718309835
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Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331707
  
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  (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
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sciencedirect.com/science/article/pii/S2451945618301193
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Systematic Functional Annotation of Somatic Mutations in Cancer

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331707
  
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  (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5926201/
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Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331707
  
  Curator: @Jmenke
  
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  (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
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pubmed.ncbi.nlm.nih.gov/29544098/
Nov 2017
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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

2
1. scibot 08 Nov 2017
  
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  AB_331707
  
  Curator: @gabimpine
  
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  RRID:AB_331707 RRIDCUR:Validated
2. scibot 08 Nov 2017
  
  in Public
  
  AB_331707
  
  Curator: @gabimpine
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2232, RRID:AB_331707)
  
  SciCrunch record: RRID:AB_331707
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5241115/