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pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Enhanced HER2 internalization by clathrin-dependent endocytosis in non-small cell lung cancer positive for HER2 mutations

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1. scibot 01 Aug 2026
  
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  RRID:AB_331725
  
  DOI: 10.1038/s41416-025-03126-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12479963/
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of payload sensitivity and other mechanisms of resistance to T-DXd in HER2-mutant NSCLC: implications for subsequent responsiveness to HER2 TKIs

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1. scibot 20 May 2026
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.jtho.2026.01.007
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13169646/
Oct 2025
www.biorxiv.org www.biorxiv.org

Metabolic Alterations driven by PFKFB3 upregulation confer Resistance to Trastuzumab in HER2-Positive Breast Cancer

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1. scibot 23 Oct 2025
  
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  RRID:AB_331725
  
  DOI: 10.1101/2025.10.09.681343
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
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biorxiv.org/content/10.1101/2025.10.09.681343v1
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

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1. scibot 20 May 2025
  
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  RRID:AB_331725
  
  DOI: 10.1158/0008-5472.CAN-24-2220
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12046322/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stromal-derived NRG1 enables oncogenic KRAS bypass in pancreas cancer

1
1. scibot 03 Mar 2024
  
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  RRID:AB_331725
  
  DOI: 10.1101/gad.351037.123
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10621596/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

EGFR-activated myofibroblasts promote metastasis of pancreatic cancer

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1. scibot 29 Dec 2023
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.ccell.2023.12.002
  
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sciencedirect.com/science/article/pii/S1535610823004300
Apr 2023
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A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression

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1. scibot 29 Apr 2023
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.ccell.2023.04.002
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
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sciencedirect.com/science/article/pii/S1535610823001289
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 11 Aug 2021
  
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  RRID:AB_331725
  
  DOI: 10.7554/eLife.29241
  
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  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5589416/
academic.oup.com academic.oup.com

Untitled document

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1. scibot 06 Aug 2021
  
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  RRID:AB_331725
  
  DOI: 10.1210/js.2018-00170
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
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academic.oup.com/jes/article/2/12/1381/5126391
May 2021
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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

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1. scibot 09 May 2021
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.stem.2020.06.021
  
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sciencedirect.com/science/article/pii/S1934590920302885
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Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex

1
1. scibot 08 May 2021
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.neuron.2020.09.034
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
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sciencedirect.com/science/article/pii/S0896627320307583
Feb 2021
mct.aacrjournals.org mct.aacrjournals.org

Predictive and Pharmacodynamic Biomarkers of Response to the Phosphatidylinositol 3-Kinase Inhibitor Taselisib in Breast Cancer Preclinical Models

1
1. scibot 24 Feb 2021
  
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  RRID:AB_331725
  
  DOI: 10.1158/1535-7163.MCT-19-0284
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
  Curator: @scibot
  
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mct.aacrjournals.org/content/19/1/292
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line

1
1. scibot 23 Sep 2020
  
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  RRID:AB_331725
  
  DOI: 10.3390/cancers12092630
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331725
  
  Curator comments: Phospho-HER2/ErbB2 (Tyr1248) Antibody Cell Signaling Technology Cat# 2247
  
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pubmed.ncbi.nlm.nih.gov/32942617/
Jan 2020
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Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.ccell.2019.09.001
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
  Curator: @ethanbadger
  
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  RRID:AB_331725 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819303848
www.sciencedirect.com www.sciencedirect.com

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

1
1. scibot 13 Jan 2020
  
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  RRID:AB_331725
  
  DOI: 10.1016/j.ccell.2018.10.001
  
  Resource: (Cell Signaling Technology Cat# 2247, RRID:AB_331725)
  
  Curator: @Jmenke
  
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  RRID:AB_331725 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610818304677
Nov 2018
watermark.silverchair.com watermark.silverchair.com

js.2018-00170.pdf

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331725
  
  Curator: @bandrow
  
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watermark.silverchair.com/js.2018-00170.pdf
www.sciencedirect.com www.sciencedirect.com

Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway

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1. scibot 05 Nov 2018
  
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  RRID:AB_331725
  
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sciencedirect.com/science/article/pii/S1550413118305096
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Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR

1
1. scibot 05 Nov 2018
  
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  RRID:AB_331725
  
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sciencedirect.com/science/article/pii/S2451945618301193
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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

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1. scibot 05 Nov 2018
  
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  RRID:AB_331725
  
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sciencedirect.com/science/article/pii/S1535610818300655
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Binding of PLD2-Generated Phosphatidic Acid to KIF5B Promotes MT1-MMP Surface Trafficking and Lung Metastasis of Mouse Breast Cancer Cells

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1. scibot 05 Nov 2018
  
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  RRID:AB_331725
  
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  (Cell Signaling Technology Cat# 2247S, RRID:AB_331725)
  
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sciencedirect.com/science/article/pii/S1534580717307359
Nov 2017
elifesciences.org elifesciences.org

Dual function of the PI3K-Akt-mTORC1 axis in myelination of the peripheral nervous system

1
1. scibot 08 Nov 2017
  
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  RRID:AB_331725
  
  Curator: @kaitlinsung
  
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  (Cell Signaling Technology Cat# 2247S, RRID:AB_331725)
  
  SciCrunch record: RRID:AB_331725
  
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  RRID:AB_331725 RRIDCUR:Validated
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elifesciences.org/articles/29241