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SPINK1-COL18A1 crosstalk shapes epigenome and drives cancer stemness in pancreatic ductal adenocarcinoma

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1. scibot 20 Aug 2026
  
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  DOI: 10.1016/j.celrep.2026.117806
  
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sciencedirect.com/science/article/pii/S2211124726008843
Aug 2026
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JI017 Sensitizes EGFR-T790M NSCLC to Erlotinib by Extinguishing the STAT3–Survivin Axis

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1. scibot 08 Aug 2026
  
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  DOI: 10.1177/15347354261475694
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13438235/
Jul 2026
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Extracellular Domain Shedding of TROP2 Activates EGFR Signaling to Drive Prostate Cancer Metastasis

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1. scibot 11 Jul 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-4855
  
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aacrjournals.org/cancerres/article/85/23/4632/767291/Extracellular-Domain-Shedding-of-TROP2-Activates
Sep 2025
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BRAFV600E-Driven Lung Tumorigenesis Requires Ligand-Mediated Activation of ERBB Receptor Signaling

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1. scibot 25 Sep 2025
  
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  DOI: 10.1101/2025.05.04.652129
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12248061/
Jul 2025
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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102253
  
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sciencedirect.com/science/article/pii/S266637912500326X
Aug 2024
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Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

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1. scibot 13 Aug 2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11826463/
Dec 2023
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Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113603
  
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sciencedirect.com/science/article/pii/S2211124723016157
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Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding

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1. scibot 16 Dec 2023
  
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  DOI: 10.1038/s41467-023-43931-7
  
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2. scibot 16 Dec 2023
  
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  DOI: 10.1038/s41467-023-43931-7
  
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nature.com/articles/s41467-023-43931-7
Oct 2023
52.53.155.43 52.53.155.43

The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers

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1. scibot 14 Oct 2023
  
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  DOI: 10.1101/2023.06.16.545259
  
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52.53.155.43/e45e39aa6be90d4518c1365e2458466145a6420b/2023.06.16.545259v2.full-html.html
Sep 2023
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Promoting the activity of a receptor tyrosine phosphatase with a novel pH‐responsive transmembrane agonist inhibits cancer‐associated phenotypes

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1. scibot 02 Sep 2023
  
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  DOI: 10.1002/pro.4742
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10461461/
Jun 2023
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Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma

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1. scibot 03 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112581
  
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sciencedirect.com/science/article/pii/S2211124723005922
Feb 2023
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Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy

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1. scibot 11 Feb 2023
  
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  DOI: 10.1016/j.isci.2023.106064
  
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sciencedirect.com/science/article/pii/S2589004223001414
Dec 2022
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Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma

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1. scibot 03 Dec 2022
  
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  DOI: 10.1158/2159-8290.CD-22-0287
  
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aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
Nov 2022
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Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling

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1. scibot 03 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111581
  
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sciencedirect.com/science/article/pii/S2211124722014462
Oct 2022
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Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas

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1. scibot 22 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.024
  
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sciencedirect.com/science/article/pii/S1097276522009340
May 2022
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EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma

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1. scibot 13 May 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1168
  
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aacrjournals.org/cancerdiscovery/article/12/5/1378/694560/EGFR-Inhibition-Potentiates-FGFR-Inhibitor-Therapy
Apr 2022
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Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis

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1. scibot 26 Apr 2022
  
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  DOI: 10.1016/j.isci.2022.104211
  
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sciencedirect.com/science/article/pii/S2589004222004813
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Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells

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1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.chembiol.2022.03.010
  
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sciencedirect.com/science/article/pii/S2451945622001271
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Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma

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1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.celrep.2022.110712
  
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sciencedirect.com/science/article/pii/S2211124722004739
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling

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1. scibot 02 Dec 2021
  
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  DOI: 10.1158/1535-7163.MCT-20-0640
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
Aug 2021
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Untitled document

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1. scibot 10 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.09.013
  
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sciencedirect.com/science/article/pii/S107476131830428X
Sep 2020
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Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer

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1. scibot 06 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107994
  
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sciencedirect.com/science/article/pii/S2211124720309797
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Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients

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1. scibot 06 Sep 2020
  
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  DOI: 10.1038/s12276-020-0413-1
  
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nature.com/articles/s12276-020-0413-1
Jan 2020
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

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  DOI: 10.1016/j.cell.2019.09.008
  
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sciencedirect.com/science/article/pii/S0092867419310141
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Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.05.017
  
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sciencedirect.com/science/article/pii/S221112471930628X
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LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.063
  
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sciencedirect.com/science/article/pii/S2211124719315542
elifesciences.org elifesciences.org

Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66/NgR-independent targeting of NogoA

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.49175
  
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elifesciences.org/articles/49175
Nov 2018
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Single Particle Imaging of Polarized Hepatoma Organoids upon Hepatitis C Virus Infection Reveals an Ordered and Sequential Entry Process

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1. scibot 05 Nov 2018
  
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Mechanism of Allosteric Coupling into and through the Plasma Membrane by EGFR

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2451945618301193
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Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818300655
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

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1. scibot 08 Nov 2017
  
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2. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5241115/