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Single-cell exploration of gonadal somatic cell lineage specification during human sex determination

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.devcel.2025.09.011
  
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sciencedirect.com/science/article/pii/S1534580725005714
Sep 2025
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Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.009
  
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sciencedirect.com/science/article/pii/S1534580725005295
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Overlapping peri-implantation phenotypes of ZNHIT1 and ZNHIT2 despite distinct functions during early mouse development

1
1. scibot 06 Sep 2025
  
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  DOI: 10.1093/biolre/ioae128
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11565232/
Jun 2025
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Generation of Human Naïve Pluripotent Stem Cell-Derived Blastoids in Thermoformed Microwell Platforms

1
1. scibot 26 Jun 2025
  
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  DOI: 10.1007/7651_2025_644
  
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link.springer.com/protocol/10.1007/7651_2025_644
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Physiological role and mechanisms of action for a long noncoding haplotype region

1
1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115805
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12263090/
May 2025
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hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation

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1. scibot 21 May 2025
  
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  DOI: 10.1186/s40478-025-02000-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
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Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.025
  
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sciencedirect.com/science/article/pii/S0092867425004581
Apr 2025
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Global analysis of protein turnover dynamics in single cells

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.002
  
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sciencedirect.com/science/article/pii/S0092867425002752
Mar 2025
www.cell.com www.cell.com

Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming

1
1. scibot 23 Mar 2025
  
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  DOI: 10.1016/j.stem.2025.02.015
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(25)00083-9
Jan 2025
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Modeling early gastrulation in human blastoids with DNA methylation patterns of natural blastocysts

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.stem.2024.12.010
  
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sciencedirect.com/science/article/pii/S1934590924004508
Nov 2024
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Generation of human induced pluripotent stem cell lines derived from patients of cystic biliary atresia

1
1. scibot 16 Nov 2024
  
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  DOI: 10.1007/s13577-024-01147-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11557646/
Aug 2024
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Generation of a heterozygous Calsequestrin 2 F189L iPSC line (UMGi158-B) by CRISPR/Cas9 genome editing to investigate the cardiac pathophysiology of Takotsubo Syndrome and Catecholaminergic Polymorphic ventricular Tachycardia

1
1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.scr.2024.103538
  
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sciencedirect.com/science/article/pii/S1873506124002368
Jun 2024
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Generation of an Alagille Syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi036-A) carrying a heterozygous mutation (p.Cys693*) in the JAG1 gene

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1. scibot 07 Jun 2024
  
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  DOI: 10.1016/j.scr.2024.103429
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11144073/
May 2024
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Generation of human induced pluripotent stem cell lines derived from four Rett syndrome patients with MECP2 mutations

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1. scibot 07 May 2024
  
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  DOI: 10.1016/j.scr.2024.103432
  
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sciencedirect.com/science/article/pii/S1873506124001302
Apr 2024
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Oct4 controls basement membrane development during human embryogenesis

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.007
  
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sciencedirect.com/science/article/pii/S1534580724001758
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Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation

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1. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.scr.2024.103409
  
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2. scibot 02 Apr 2024
  
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  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2024.103409
  
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sciencedirect.com/science/article/pii/S1873506124001077
Jan 2024
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Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.molcel.2023.12.007
  
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sciencedirect.com/science/article/pii/S1097276523010262
Dec 2023
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Generation of five induced pluripotent stem cell lines from patients with MECP2 Duplication Syndrome

1
1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.scr.2023.103292
  
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sciencedirect.com/science/article/pii/S1873506123002787
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Generation of an RBM20-mutation-associated left-ventricular non-compaction cardiomyopathy iPSC line (UMGi255-A) into a DCM genetic background to investigate monogenetic cardiomyopathies

1
1. scibot 23 Dec 2023
  
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  DOI: 10.1016/j.scr.2023.103290
  
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sciencedirect.com/science/article/pii/S1873506123002763
Nov 2023
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Generation of a CRISPR/Cas9-edited Plakoglobin (JUP)knock-out (JMUi001-A-4) iPSC line to model the cardiac phenotype of arrhythmogenic cardiomyopathy

1
1. scibot 17 Nov 2023
  
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  DOI: 10.1016/j.scr.2023.103240
  
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sciencedirect.com/science/article/pii/S187350612300226X
Oct 2023
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Generation of a human induced pluripotent stem cell line (UMGACBi001-A) from urine cells of a chronic kidney disease patient with hypertension, diabetic nephropathy and acute sepsis

1
1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.scr.2023.103224
  
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sciencedirect.com/science/article/pii/S1873506123002106
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Generation of an Alagille syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi032-A) carrying a heterozygous mutation (p.Cys682Leufs*7) in the JAG1 gene

1
1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.scr.2023.103231
  
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sciencedirect.com/science/article/pii/S1873506123002179
May 2023
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Ex utero monkey embryogenesis from blastocyst to early organogenesis

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.020
  
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sciencedirect.com/science/article/pii/S0092867423004166
Apr 2023
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NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency

1
1. scibot 22 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112372
  
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sciencedirect.com/science/article/pii/S2211124723003832
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Cynomolgus monkey embryo model captures gastrulation and early pregnancy

1
1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.stem.2023.03.009
  
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sciencedirect.com/science/article/pii/S1934590923000802
Jan 2023
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Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence

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1. scibot 24 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112021
  
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sciencedirect.com/science/article/pii/S2211124723000323
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection

1
1. scibot 16 Dec 2022
  
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  DOI: 10.1016/j.xcrm.2022.100849
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9671691/
Oct 2022
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Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells

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1. scibot 01 Oct 2022
  
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  DOI: 10.1016/j.devcel.2022.09.006
  
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sciencedirect.com/science/article/pii/S1534580722006360
Jul 2022
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Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient

1
1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.scr.2022.102865
  
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sciencedirect.com/science/article/pii/S1873506122002148
Jun 2022
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In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells

1
1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.stem.2022.05.001
  
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sciencedirect.com/science/article/pii/S1934590922002016
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells

1
1. scibot 01 Jun 2022
  
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  DOI: 10.7554/eLife.71533
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9142147/
May 2022
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Corrigendum to “Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for PTCH1 gene” [Stem Cell Res. 56 (2021) 102517]

1
1. scibot 26 May 2022
  
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  DOI: 10.1016/j.scr.2022.102817
  
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sciencedirect.com/science/article/pii/S1873506122001660
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Glioblastoma Embryonic-like Stem Cells Exhibit Immune-Evasive Phenotype

1
1. scibot 18 May 2022
  
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  RRID:AB_354975
  
  DOI: 10.3390/cancers14092070
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9104850/
Mar 2022
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Generation of human induced pluripotent stem cell lines derived from 4 DiGeorge syndrome patients with 22q11.2 deletion

1
1. scibot 11 Mar 2022
  
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  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2022.102744
  
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scibot

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sciencedirect.com/science/article/pii/S1873506122000939
Feb 2022
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Establishment of a Developmental Toxicity Assay based on Human iPSC Reporter to Detect Fibroblast Growth Factor Signal Disruption

1
1. scibot 04 Feb 2022
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.isci.2022.103770
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975
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sciencedirect.com/science/article/pii/S2589004222000402
Jan 2022
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Generation of homozygous Nav1.8 knock-out iPSC lines by CRISPR Cas9 genome editing

1
1. scibot 21 Jan 2022
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2022.102677
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975
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sciencedirect.com/science/article/pii/S1873506122000265
Oct 2021
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Generation of human induced pluripotent stem cell lines carrying homozygous JAG1 deletions

1
1. scibot 28 Oct 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102588
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975
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sciencedirect.com/science/article/pii/S1873506121004359
Sep 2021
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Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for PTCH1 gene

2
1. scibot 04 Sep 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102517
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975
2. scibot 04 Sep 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102517
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975
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sciencedirect.com/science/article/pii/S1873506121003640
Jun 2021
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Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls

1
1. scibot 19 Jun 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102435
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975
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sciencedirect.com/science/article/pii/S1873506121002828
Apr 2021
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Generation of two additional integration-free iPSC lines from related human donors

1
1. scibot 17 Apr 2021
  
  in Public
  
  AB_354975
  
  DOI: 10.1016/j.scr.2021.102327
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRIDCUR:Validated RRID:AB_354975
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RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S1873506121001732
www.sciencedirect.com www.sciencedirect.com

Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo

1
1. scibot 16 Apr 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.cell.2021.03.020
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867421003056
www.sciencedirect.com www.sciencedirect.com

Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations

1
1. scibot 16 Apr 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102337
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1873506121001835
Feb 2021
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Generation and cardiac differentiation of an induced pluripotent stem cell line from a patient with arrhythmia-induced cardiomyopathy

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102263
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975 RRIDCUR:Validated
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RRID:AB_354975

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scibot

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sciencedirect.com/science/article/pii/S1873506121001094
www.sciencedirect.com www.sciencedirect.com

Generation of iPSC lines from CPVT patient carrying heterozygous mutation p.A2254V in the ryanodine receptor 2 gene

1
1. scibot 24 Feb 2021
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2021.102259
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRIDCUR:Validated RRID:AB_354975
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RRID:AB_354975

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scibot

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sciencedirect.com/science/article/pii/S1873506121001057
Sep 2020
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Generation of iPSC-lines from two independent Takotsubo syndrome patients with recurrent TTS events

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2020.101746
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975 RRIDCUR:Validated
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RRID:AB_354975

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scibot

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sciencedirect.com/science/article/pii/S1873506120300507
www.sciencedirect.com www.sciencedirect.com

Generation of pluripotent stem cell lines and CRISPR/Cas9 modified isogenic controls from a patient with dilated cardiomyopathy harboring a RBM20 p.R634W mutation

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2020.101901
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_354975
  
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  RRID:AB_354975 RRIDCUR:Validated
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RRID:AB_354975

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scibot

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sciencedirect.com/science/article/pii/S1873506120302026
www.sciencedirect.com www.sciencedirect.com

Generation of two human induced pluripotent stem cell lines derived from two juvenile nephronophthisis patients with NPHP1 deletion

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:AB_354975
  
  DOI: 10.1016/j.scr.2020.101815
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_354975
  
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  RRIDCUR:Validated RRID:AB_354975
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scibot

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sciencedirect.com/science/article/pii/S1873506120301173
Jan 2020
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Generation of four integration-free iPSC lines from related human donors

1
1. scibot 13 Jan 2020
  
  in Public
  
  AB_354975
  
  DOI: 10.1016/j.scr.2019.101615
  
  Resource: (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  Curator: @ethanbadger
  
  SciCrunch record: AB_354975
  
  What is this?
  
  RRID:AB_354975 RRIDCUR:Validated
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RRID:AB_354975

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scibot

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sciencedirect.com/science/article/pii/S1873506119302454
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_354975
  
  Resource used:
  
  (R and D Systems Cat# AF1759, RRID:AB_354975)
  
  SciCrunch record: RRID:AB_354975
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_354975
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RRID:AB_354975

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scibot

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sciencedirect.com/science/article/pii/S1097276517301739