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23 Matching Annotations

Feb 2026
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Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.chembiol.2026.01.006
  
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sciencedirect.com/science/article/pii/S2451945626000267
Jan 2026
dx.doi.org dx.doi.org

Enhancing Tyro3 signaling ameliorates IL-1β production through STAT1 in Alzheimer's disease models

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1. scibot 13 Jan 2026
  
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  DOI: 10.1093/jleuko/qiaf157
  
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dx.doi.org/10.1093/jleuko/qiaf157
Sep 2025
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A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation

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1. scibot 11 Sep 2025
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.chembiol.2025.08.006
  
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sciencedirect.com/science/article/pii/S2451945625002594
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The glycolytic metabolite methylglyoxal covalently inactivates the NLRP3 inflammasome

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1. scibot 19 Apr 2025
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.celrep.2024.114688
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12005378/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia

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1. scibot 04 Mar 2025
  
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  DOI: 10.1002/advs.202414260
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12021055/
Mar 2024
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Matrilin-3 supports neuroprotection in ischemic stroke by suppressing astrocyte-mediated neuroinflammation

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1. scibot 27 Mar 2024
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.celrep.2024.113980
  
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sciencedirect.com/science/article/pii/S2211124724003085
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gasdermin-D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway

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1. scibot 10 Jan 2024
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.isci.2023.108463
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10767184/
Mar 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro

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1. scibot 30 Mar 2023
  
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  RRID:AB_378141
  
  DOI: 10.1111/jnc.15778
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15778
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

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1. scibot 17 Dec 2022
  
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  AB_378141
  
  DOI: 10.7554/eLife.78609
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9754625/
aacrjournals.org aacrjournals.org

Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma

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1. scibot 04 Dec 2022
  
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  RRID:AB_378141
  
  DOI: 10.1158/1541-7786.MCR-22-0040
  
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aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
Oct 2022
52.53.155.43 52.53.155.43

mcr-22-0040-html.html

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1. scibot 28 Oct 2022
  
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  RRID:AB_378141
  
  DOI: 10.1158/1541-7786.MCR-22-0040
  
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52.53.155.43/727478f306d650986e0e949733013801988f63e4/mcr-22-0040-html.html
Aug 2022
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Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

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1. scibot 17 Aug 2022
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.celrep.2022.111205
  
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sciencedirect.com/science/article/pii/S2211124722010221
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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging

1
1. scibot 13 Aug 2022
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.immuni.2022.07.007
  
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sciencedirect.com/science/article/pii/S1074761322003405
Jul 2021
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

1
1. scibot 22 Jul 2021
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.cell.2021.06.028
  
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sciencedirect.com/science/article/pii/S0092867421007960
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

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1. scibot 08 Jul 2021
  
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  DOI: 10.7554/eLife.66522
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8245129/
Oct 2020
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TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity

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1. scibot 31 Oct 2020
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.celrep.2020.108326
  
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  RRIDCUR:Validated RRID:AB_378141
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sciencedirect.com/science/article/pii/S2211124720313152
Sep 2020
www.cell.com www.cell.com

Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

1
1. scibot 17 Sep 2020
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.immuni.2017.10.016
  
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  RRID:AB_378141 RRIDCUR:Validated
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cell.com/immunity/abstract/S1074-7613(17)30471-5
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A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling

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1. scibot 08 Sep 2020
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.celrep.2020.03.030
  
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  Curator: @ethanbadger
  
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  RRID:AB_378141 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720303442
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β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

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1. scibot 05 Sep 2020
  
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  RRID:AB_378141
  
  DOI: 10.1016/j.celrep.2020.02.025
  
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  RRIDCUR:Validated RRID:AB_378141
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sciencedirect.com/science/article/pii/S2211124720301868
Nov 2018
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Untitled document

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S2211124718310696
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By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761317304211
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Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761317304715
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The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1074761317305149