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Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.10.003
  
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sciencedirect.com/science/article/pii/S1074761325004339
Oct 2025
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TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.011
  
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sciencedirect.com/science/article/pii/S1535610825004039
Aug 2025
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Caveolin-1/PPARα axis suppresses T follicular helper cell response in primary Sjögren disease

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116156
  
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sciencedirect.com/science/article/pii/S2211124725009271
Jul 2025
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2025.07.10.664251v1.full-html.html

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1. scibot 22 Jul 2025
  
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  DOI: 10.1101/2025.07.10.664251
  
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52.53.155.43/1cfa6b550b40cdda3522311aa4275c22b0c379c4/2025.07.10.664251v1.full-html.html
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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  DOI: 10.1016/j.immuni.2025.06.006
  
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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.03.036
  
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sciencedirect.com/science/article/pii/S1535610825001370
Apr 2025
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1-s2.0-S258900422500625X-main-html.html

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1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112364
  
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52.53.155.43/910d735d2d974315eeec93884560c504f16aaecd/1-s2.0-S258900422500625X-main-html.html
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An erythroid-biased FOShi hematopoietic multipotent progenitor subpopulation contributes to adaptation to chronic hypoxia

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.stem.2025.03.010
  
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sciencedirect.com/science/article/pii/S1934590925001006
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115566
  
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sciencedirect.com/science/article/pii/S2211124725003377
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Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control

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1. scibot 11 Apr 2025
  
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  DOI: 10.1101/2024.10.16.618635
  
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52.53.155.43/ecad09cc9eabd42f0fef0391e2d71b5d66664c67/2024.10.16.618635.full-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115510
  
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sciencedirect.com/science/article/pii/S2211124725002815
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Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii

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1. scibot 02 Apr 2025
  
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  DOI: 10.1038/s41564-025-01967-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11964939/
Dec 2024
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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.10.014
  
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sciencedirect.com/science/article/pii/S1535610824004021
Aug 2024
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Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells

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1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.07.021
  
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sciencedirect.com/science/article/pii/S1097276524006191
Jul 2024
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Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.immuni.2024.06.014
  
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Prenatal inflammation remodels lung immunity and function by programming ILC2 hyperactivation

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1. scibot 20 Jul 2024
  
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  AB_389211
  
  DOI: 10.1016/j.celrep.2024.114365
  
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sciencedirect.com/science/article/pii/S2211124724006934
www.cell.com www.cell.com

BTLA and PD-1 signals attenuate TCR-mediated transcriptomic changes

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110253
  
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cell.com/iscience/abstract/S2589-0042(24)01478-0
Jun 2024
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Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.immuni.2024.05.009
  
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sciencedirect.com/science/article/pii/S1074761324002632
May 2024
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Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression

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1. scibot 30 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.004
  
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sciencedirect.com/science/article/pii/S1074761324002553
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The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

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1. scibot 24 May 2024
  
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  DOI: 10.1101/2024.03.05.583527
  
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biorxiv.org/content/10.1101/2024.03.05.583527v1
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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sciencedirect.com/science/article/pii/S2211124724005862
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SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.stem.2024.04.023
  
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sciencedirect.com/science/article/pii/S1934590924001760
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.023
  
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sciencedirect.com/science/article/pii/S0092867424004483
Apr 2024
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Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer

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  DOI: 10.1016/j.ccell.2024.03.005
  
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sciencedirect.com/science/article/pii/S1535610824000904
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Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling

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1. scibot 02 Apr 2024
  
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  RRID:AB_389211
  
  DOI: 10.1126/scisignal.adh0439
  
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science.org/doi/10.1126/scisignal.adh0439
Mar 2024
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Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.114003
  
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sciencedirect.com/science/article/pii/S2211124724003310
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transcriptional reprogramming via signaling domains of CD2, CD28 and 4-1BB

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1. scibot 09 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109267
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10918215/
Jan 2024
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Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.chom.2023.12.006
  
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sciencedirect.com/science/article/pii/S1931312823005012
Dec 2023
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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.018
  
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sciencedirect.com/science/article/pii/S1074761323005009
52.53.155.43 52.53.155.43

qiad158-html.html

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  DOI: 10.1093/jleuko/qiad158
  
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52.53.155.43/42c899beea5620e593ae66892ac4a4239bf226aa/qiad158-html.html
Oct 2023
www.embopress.org www.embopress.org

Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL-1R/TLR signals

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1. scibot 27 Oct 2023
  
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  DOI: 10.15252/embr.202357485
  
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embopress.org/doi/10.15252/embr.202357485
52.53.155.43 52.53.155.43

Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

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1. scibot 20 Oct 2023
  
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  DOI: 10.1101/2023.09.04.556230
  
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52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
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Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells

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1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113180
  
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sciencedirect.com/science/article/pii/S2211124723011920
Jun 2023
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Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

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1. scibot 22 Jun 2023
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.molcel.2023.05.035
  
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NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation

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B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection

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A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

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Continuous germinal center invasion contributes to the diversity of the immune response

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Periostin activates distinct modules of inflammation and itching downstream of the type 2 inflammation pathway

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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output

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Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse

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TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

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Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors

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Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

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Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

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CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture

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Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease

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Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a

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A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells

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Evaluation of Marijuana Compounds on Neuroimmune Endpoints in Experimental Autoimmune Encephalomyelitis

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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

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Untitled document

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Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity

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SPNS2 enables T cell egress from lymph nodes during an immune response

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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

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Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

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May 2021
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Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

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Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection

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Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M

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Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche

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Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β

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The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

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Immunogenomic Landscape of Hematological Malignancies

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections

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A Two-Step Process of Effector Programming Governs CD4+ T Cell Fate Determination Induced by Antigenic Activation in the Steady State

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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

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  APC anti-mouse CD45.2 Antibody (clone 104)
  
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sciencedirect.com/science/article/pii/S221112472031370X
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Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

1
1. scibot 07 Nov 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.molcel.2020.10.012
  
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sciencedirect.com/science/article/pii/S109727652030719X
Oct 2020
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Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function

1
1. scibot 27 Oct 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.stem.2020.09.018
  
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sciencedirect.com/science/article/pii/S1934590920304938
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Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers

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1. scibot 26 Sep 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2019.12.058
  
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Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils

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1. scibot 25 Sep 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2020.108164
  
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pubmed.ncbi.nlm.nih.gov/32966785/
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Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity

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1. scibot 13 Sep 2020
  
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  AB_389211
  
  DOI: 10.1016/j.celrep.2020.107818
  
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The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis

1
1. scibot 05 Sep 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2020.02.098
  
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sciencedirect.com/science/article/pii/S2211124720302722
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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2019.05.020
  
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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.ccell.2019.10.006
  
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sciencedirect.com/science/article/pii/S1535610819304805
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2019.09.065
  
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Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2019.05.028
  
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sciencedirect.com/science/article/pii/S2211124719306394
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_389211
  
  DOI: 10.1016/j.celrep.2019.03.105
  
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sciencedirect.com/science/article/pii/S2211124719304528
Nov 2018
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Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

1
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sciencedirect.com/science/article/pii/S1931312818304104
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Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

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1. scibot 05 Nov 2018
  
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Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

1
1. scibot 05 Nov 2018
  
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  RRID:AB_389211
  
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Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis

1
1. scibot 05 Nov 2018
  
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  RRID:AB_389211
  
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sciencedirect.com/science/article/pii/S1074761318301468
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

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1. scibot 05 Nov 2018
  
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onlinelibrary.wiley.com/doi/10.1002/cptx.43/full
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CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells

1
1. scibot 05 Nov 2018
  
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  RRID:AB_389211
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5728720/
Nov 2017
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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

1
1. scibot 08 Nov 2017
  
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  RRID:AB_389211
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1074761317303151

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