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T cell cross-priming by PD-L1+ type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1×4-1BB bispecific antibody

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Oct 2026
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2026.10.14.759124.full-html.html

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54.241.53.176/0169a1ce998e4cb60ef6d7df994b1ebbbf75d6a6/2026.10.14.759124.full-html.html
Sep 2026
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Copper ion-induced MYH9 polymerization executes cuproptosis

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  DOI: 10.1016/j.cell.2026.08.030
  
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sciencedirect.com/science/article/pii/S0092867426010032
May 2026
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Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.isci.2026.115978
  
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Loss of the autoimmune risk gene TREX1 reveals a convergence of mechanisms promoting immune tolerance loss and antitumor immunity

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  DOI: 10.1126/sciadv.aea6842
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13148304/
Apr 2026
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An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment

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A Rasa3-Gαi signaling axis orchestrates B lymphocyte trafficking into and through lymphoid organs

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  DOI: 10.1016/j.celrep.2026.117243
  
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Mar 2026
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6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.neuron.2026.02.028
  
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1-s2.0-S2589004226006887-main-html.html

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Feb 2026
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The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors

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Divergent tumor immunity determined by bacteria-cancer cell engagement

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  DOI: 10.1016/j.cell.2025.12.044
  
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sciencedirect.com/science/article/pii/S009286742501493X
Dec 2025
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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.chom.2025.11.008
  
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sciencedirect.com:5037/science/article/pii/S1931312825004688
Nov 2025
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DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma

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1. scibot 26 Nov 2025
  
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  DOI: 10.1158/2326-6066.CIR-25-0086
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12642826/
Oct 2025
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Intravascular immune surveillance against viremia requires spatiotemporal coordination between Kupffer cells and ILC1s

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Molnupiravir inhibits Bourbon virus infection and disease-associated pathology in mice

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  DOI: 10.1128/jvi.00740-25
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12548437/
Aug 2025
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Bifidobacterium animalis suppresses non-small cell lung cancer progression and modulates tumor immunity through indole-3-acetic acid

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  DOI: 10.1016/j.celrep.2025.116132
  
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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Jul 2025
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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  DOI: 10.1016/j.immuni.2025.06.006
  
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May 2025
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Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion

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Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B

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Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

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Apr 2025
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ULBP2 Promotes Tumor Progression by Suppressing NKG2D-Mediated Anti-Tumor Immunity

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  DOI: 10.3390/ijms26072950
  
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Mar 2025
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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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Feb 2025
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Dynamics of tissue repair regulatory T cells and damage in acute Trypanosoma cruzi infection

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  DOI: 10.1371/journal.ppat.1012906
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11813105/
Oct 2024
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MerTK+ macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activation

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  DOI: 10.1126/sciadv.ado8366
  
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Macrophage-mediated myelin recycling fuels brain cancer malignancy

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  DOI: 10.1016/j.cell.2024.07.030
  
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Jul 2024
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Primary nasal influenza infection rewires tissue-scale memory response dynamics

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Feb 2024
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Suppression of adaptive NK cell expansion by macrophage-mediated phagocytosis inhibited by 2B4-CD48

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  DOI: 10.1016/j.celrep.2024.113800
  
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Dec 2023
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Circulating NK cells establish tissue residency upon acute infection of skin and mediate accelerated effector responses to secondary infection

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  DOI: 10.1016/j.immuni.2023.11.018
  
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Nov 2023
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Bcl6 is a subset-defining transcription factor of lymphoid tissue inducer-like ILC3

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  DOI: 10.1016/j.celrep.2023.113425
  
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Aug 2023
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METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy

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  DOI: 10.1016/j.xcrm.2023.101144
  
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sciencedirect.com/science/article/pii/S2666379123002975
Jul 2023
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Defining iNKT Cell Subsets and Their Function by Flow Cytometry

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  DOI: 10.1002/cpz1.838
  
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currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.838
Jan 2023
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Neutrophil-activating therapy for the treatment of cancer

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1. scibot 27 Jan 2023
  
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  DOI: 10.1016/j.ccell.2023.01.002
  
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T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.12.010
  
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Sep 2022
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In vivo G-CSF treatment activates the GR-SOCS1 axis to suppress IFN-γ secretion by natural killer cells

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  DOI: 10.1016/j.celrep.2022.111342
  
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Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

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Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation

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Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription

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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity

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Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells

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Natural Killer Cells Promote Fetal Development through the Secretion of Growth-Promoting Factors

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Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses

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Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

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Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation

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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

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Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response

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Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

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Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity

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Dysfunction of Natural Killer Cells by FBP1-Induced Inhibition of Glycolysis during Lung Cancer Progression

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Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4

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