207 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    1. scibot 24 Apr 2024
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      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  3. Feb 2024
  4. 52.53.155.43 52.53.155.43
    mTOR regulates mineralocorticoid receptor transcriptional activity by ULK1- dependent and independent mechanisms
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    1. scibot 15 Feb 2024
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      DOI: 10.1210/endocr/bqae015

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    52.53.155.43/6951e0010ae4c14df11b3315f954e81c6a9c88a4/bqae015-html.html
  5. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
    1. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.05.570182

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    2. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.05.570182

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    3. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.05.570182

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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  6. Jan 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  8. Dec 2023
  9. www.sciencedirect.com www.sciencedirect.com
    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.cell.2023.09.027

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    sciencedirect.com/science/article/pii/S0092867423010814
  10. Nov 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.molcel.2023.10.017

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    sciencedirect.com/science/article/pii/S1097276523008547
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    The tRNA-GCN2-FBXO22-axis-mediated mTOR ubiquitination senses amino acid insufficiency
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cmet.2023.10.016

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    sciencedirect.com/science/article/abs/pii/S1550413123003856
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    PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cmet.2023.11.001

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    sciencedirect.com/science/article/abs/pii/S1550413123004114
  14. www.sciencedirect.com www.sciencedirect.com
    Acid ceramidase regulates innate immune memory
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113458

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    sciencedirect.com/science/article/pii/S2211124723014705
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    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.molcel.2021.03.010

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    sciencedirect.com/science/article/pii/S1097276521001787
  16. www.embopress.org www.embopress.org
    Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism
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    1. scibot 17 Nov 2023
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      DOI: 10.15252/embr.202357339

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    embopress.org/doi/full/10.15252/embr.202357339
  17. www.sciencedirect.com www.sciencedirect.com
    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    1
    1. scibot 05 Nov 2023
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      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
  18. 52.53.155.43 52.53.155.43
    s11684-022-0959-5 (1)-html.html
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    1. scibot 03 Nov 2023
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      DOI: 10.3389/fncel.2020.552213

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      DOI: 10.3389/fncel.2020.552213

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  19. Oct 2023
  20. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.15252/embr.202356815

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    embopress.org/doi/10.15252/embr.202356815
  21. Sep 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Examining PI3K-signaling-dependent regulation of lens organelle free zone formation via immunolocalization and immunoblotting in chick embryos
    1
    1. scibot 23 Sep 2023
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      DOI: 10.1016/j.xpro.2023.102569

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    ncbi.nlm.nih.gov/pmc/articles/PMC10509694/
  23. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Resistance wheel running improves contractile strength, but not metabolic capacity, in a murine model of volumetric muscle loss injury
    1
    1. scibot 14 Sep 2023
      RRID:AB_390722

      DOI: 10.1113/EP091284

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    physoc.onlinelibrary.wiley.com/doi/10.1113/EP091284
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities
    1
    1. scibot 07 Sep 2023
      RRID:AB_390722

      DOI: 10.1158/2643-3230.BCD-22-0082

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    ncbi.nlm.nih.gov/pmc/articles/PMC9975769/
  25. Aug 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A stepwise and digital pattern of RSK phosphorylation determines the outcome of thymic selection
    1
    1. scibot 31 Aug 2023
      RRID:AB_390722

      DOI: 10.1016/j.isci.2023.107552

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    ncbi.nlm.nih.gov/pmc/articles/PMC10460994/
  27. Jul 2023
  28. www.sciencedirect.com www.sciencedirect.com
    mTOR inhibition reprograms cellular proteostasis by regulating eIF3D-mediated selective mRNA translation and promotes cell phenotype switching
    1
    1. scibot 27 Jul 2023
      RRID:AB_390722

      DOI: 10.1016/j.celrep.2023.112868

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    sciencedirect.com/science/article/pii/S2211124723008793
  29. www.sciencedirect.com www.sciencedirect.com
    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112779

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    sciencedirect.com/science/article/pii/S2211124723007908
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”
    1
    1. scibot 22 Jun 2023
      RRID:AB_390722

      DOI: 10.1016/j.celrep.2023.112632

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    sciencedirect.com/science/article/pii/S2211124723006435
  32. www.sciencedirect.com www.sciencedirect.com
    DHX9-mediated pathway contributes to the malignant phenotype of Myelodysplastic syndromes
    1
    1. scibot 09 Jun 2023
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      DOI: 10.1016/j.isci.2023.106962

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    sciencedirect.com/science/article/pii/S2589004223010398
  33. May 2023
  34. 52.53.155.43 52.53.155.43
    s11684-022-0959-5-html.html
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    1. scibot 27 May 2023
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      DOI: 10.1016/j.lungcan.2010.01.001

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    2. scibot 25 May 2023
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      DOI: 10.1007/s11684-022-0959-5

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    52.53.155.43/2a5df239930e05a1fe550ae7329d1c04600de669/s11684-022-0959-5 (1)-html.html
  35. www.sciencedirect.com www.sciencedirect.com
    FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation
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    1. scibot 20 May 2023
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      DOI: 10.1016/j.celrep.2023.112530

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    sciencedirect.com/science/article/pii/S2211124723005417
  36. www.sciencedirect.com www.sciencedirect.com
    LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation
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    1. scibot 12 May 2023
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      DOI: 10.1016/j.molcel.2023.04.017

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    sciencedirect.com/science/article/pii/S1097276523002885
  37. www.embopress.org www.embopress.org
    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
    1
    1. scibot 09 May 2023
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      DOI: 10.15252/embj.2022112362

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    embopress.org/doi/10.15252/embj.2022112362
  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration
    1
    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.neuron.2023.04.006

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    sciencedirect.com/science/article/pii/S0896627323002684
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    ZFP36-mediated mRNA decay regulates metabolism
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      DOI: 10.1016/j.celrep.2023.112411

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    sciencedirect.com/science/article/pii/S2211124723004229
  41. europepmc.org europepmc.org
    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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      DOI: 10.1016/j.isci.2023.106526

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    europepmc.org/article/pmc/pmc10105291
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
    1
    1. scibot 09 Apr 2023
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      DOI: 10.7554/eLife.78629

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    ncbi.nlm.nih.gov/pmc/articles/PMC10069870/
  43. Mar 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons
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      DOI: 10.1016/j.celrep.2023.112180

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    sciencedirect.com/science/article/pii/S2211124723001912
  45. Feb 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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      DOI: 10.1016/j.isci.2023.106045

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    ncbi.nlm.nih.gov/pmc/articles/PMC9932127/
  47. www.sciencedirect.com www.sciencedirect.com
    PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6
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      DOI: 10.1016/j.isci.2023.106070

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    sciencedirect.com/science/article/pii/S2589004223001475
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
    1
    1. scibot 15 Feb 2023
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      DOI: 10.7554/eLife.86471

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910825/
  49. www.sciencedirect.com www.sciencedirect.com
    β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence
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      DOI: 10.1016/j.mito.2022.12.004

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    sciencedirect.com/science/article/pii/S1567724922001088
  50. Jan 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
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    1. scibot 25 Jan 2023
      RRID:AB_390722

      DOI: 10.1016/j.celrep.2022.111965

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    sciencedirect.com/science/article/pii/S2211124722018691
  52. Nov 2022
  53. academic.oup.com academic.oup.com
    mTOR inhibition decreases angiotensin II-induced steroidogenesis in HAC15 human adrenocortical carcinoma cells
    1
    1. scibot 19 Nov 2022
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      DOI: 10.1210/endocr/bqac185

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    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
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    Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation
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    Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites
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  60. Aug 2022
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    Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
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  62. 52.53.155.43 52.53.155.43
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  63. Jul 2022
  64. www.sciencedirect.com www.sciencedirect.com
    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
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    Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome
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    Neuron-specific translational control shift ensures proteostatic resilience during ER stress
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    The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis
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  68. Jun 2022
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    Pharmacological inhibition of sphingolipid synthesis reduces ferroptosis by stimulating the HIF-1 pathway.
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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  72. May 2022
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    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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  76. Apr 2022
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    Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
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    CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories
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  81. Mar 2022
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    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth
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  86. Feb 2022
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    Identification of serum and glucocorticoid-regulated kinase 1 as a regulator of signal transducer and activator of transcription 3 signaling
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  90. Jan 2022
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  95. Dec 2021
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    GFAT2 mediates cardiac hypertrophy through HBP-O-GlcNAcylation-Akt pathway
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  98. Nov 2021
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  101. Oct 2021
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    Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
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    Rheb-regulated mitochondrial pyruvate metabolism of Schwann cells linked to axon stability
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    Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
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  105. Sep 2021
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    Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns
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    A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
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  108. Aug 2021
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    Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer
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    Multisite Phosphorylation of S6K1 Directs a Kinase Phospho-code that Determines Substrate Selection
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    Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin
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    Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis
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  118. Jul 2021
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    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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    mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
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      p70 S6 Kinase

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    New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
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    Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder
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    Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism
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  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  125. www.sciencedirect.com www.sciencedirect.com
    Rapid manipulation of mitochondrial morphology in a living cell with iCMM
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    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
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    Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs
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    Distribution of dietary protein intake in daily meals influences skeletal muscle hypertrophy via the muscle clock
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    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
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  130. Jun 2021
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    DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity
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    MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages
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  133. May 2021
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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    Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function
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    Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility
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    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
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    ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis
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    Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation
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    NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
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    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
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    Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology
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    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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    Metabolic stress drives sympathetic neuropathy within the liver
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    Coordinate regulation of the senescent state by selective autophagy
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    Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
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      Rabbit anti-S6K

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    An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
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    Posttranscriptional regulation of de novo lipogenesis by glucose-induced O-GlcNAcylation
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  150. www.cell.com www.cell.com
    β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells
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      RRID:AB_390722

      DOI: 10.1016/j.cub.2021.01.081

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  151. www.sciencedirect.com www.sciencedirect.com
    Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
    1
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      DOI: 10.1016/j.celrep.2021.108944

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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
    1
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      DOI: 10.7554/eLife.63326

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  153. www.sciencedirect.com www.sciencedirect.com
    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    1
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      DOI: 10.1016/j.molcel.2021.03.009

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  154. www.sciencedirect.com www.sciencedirect.com
    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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      DOI: 10.1016/j.molcel.2021.03.010

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    sciencedirect.com/science/article/pii/S1097276521001787
  155. Mar 2021
  156. www.sciencedirect.com www.sciencedirect.com
    Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis
    1
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      RRID:AB_390722

      DOI: 10.1016/j.celrep.2021.108830

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  157. www.sciencedirect.com www.sciencedirect.com
    Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function
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      DOI: 10.1016/j.celrep.2021.108796

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    sciencedirect.com/science/article/pii/S2211124721001108
  158. Feb 2021
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translation in amino-acid-poor environments is limited by tRNAGln charging
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  160. journals.physiology.org journals.physiology.org
    A common genetic variant in ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics
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      DOI: 10.1152/ajpcell.00383.2019

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  161. journals.physiology.org journals.physiology.org
    A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics
    1
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      RRID:AB_390722

      DOI: 10.1152/ajpcell.00383.2019

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    journals.physiology.org/doi/abs/10.1152/ajpcell.00383.2019@apsselect.2020.7.issue-6
  162. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
    1
    1. scibot 24 Feb 2021
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      DOI: 10.1016/j.celrep.2020.01.012

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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  163. academic.oup.com academic.oup.com
    Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling
    1
    1. scibot 24 Feb 2021
      RRID:AB_390722

      DOI: 10.1093/cercor/bhz306

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    academic.oup.com/cercor/advance-article/doi/10.1093/cercor/bhz306/5673286
  164. onlinelibrary.wiley.com onlinelibrary.wiley.com
    IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway
    1
    1. scibot 24 Feb 2021
      AB_390

      DOI: 10.1002/advs.202001502

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    onlinelibrary.wiley.com/doi/10.1002/advs.202001502
  165. Jan 2021
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
    1
    1. scibot 26 Jan 2021
      RRID:AB_390722

      DOI: 10.1016/j.cell.2020.12.024

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    ncbi.nlm.nih.gov/pmc/articles/PMC7868890/
  167. Dec 2020
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes
    1
    1. scibot 07 Dec 2020
      RRID:AB_390722

      DOI: 10.1152/ajpcell.00148.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6957384/
  169. Nov 2020
  170. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Subcellular mRNA Localization Regulates Ribosome Biogenesis in Migrating Cells
    1
    1. scibot 17 Nov 2020
      RRID:AB_390722

      DOI: 10.1016/j.devcel.2020.10.006

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  171. www.sciencedirect.com www.sciencedirect.com
    A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells
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      RRID:AB_390722

      DOI: 10.1016/j.celrep.2020.108318

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    sciencedirect.com/science/article/pii/S2211124720313073
  172. Sep 2020
  173. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 26 Sep 2020
      RRID:AB_390722

      DOI: 10.1111/bph.15080

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15080
  174. www.sciencedirect.com www.sciencedirect.com
    Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition
    1
    1. scibot 23 Sep 2020
      RRID:AB_390722

      DOI: 10.1016/j.celrep.2020.01.080

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    sciencedirect.com/science/article/pii/S2211124720301054
  175. www.sciencedirect.com www.sciencedirect.com
    Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism
    1
    1. scibot 23 Sep 2020
      RRID:AB_390722

      DOI: 10.1016/j.cmet.2020.02.015

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    sciencedirect.com/science/article/pii/S1550413120300747
  176. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
    1
    1. scibot 23 Sep 2020
      RRID:AB_390722

      DOI: 10.7554/eLife.53367

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    elifesciences.org/articles/53367
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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    1. scibot 17 Sep 2020
      RRID:AB_390722

      DOI: 10.7554/eLife.56913

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  178. www.sciencedirect.com www.sciencedirect.com
    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
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    1. scibot 13 Sep 2020
      AB_390722

      DOI: 10.1016/j.molcel.2020.01.003

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  179. www.sciencedirect.com www.sciencedirect.com
    The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance
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      RRID:AB_390722

      DOI: 10.1016/j.devcel.2020.03.011

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    sciencedirect.com/science/article/pii/S1534580720302185
  180. www.sciencedirect.com www.sciencedirect.com
    PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells
    1
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      P70S6K

      DOI: 10.1016/j.immuni.2018.05.006

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    sciencedirect.com/science/article/pii/S1074761318302425
  181. www.sciencedirect.com www.sciencedirect.com
    Metabolic Control over mTOR-Dependent Diapause-like State
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      RRID:AB_390722

      DOI: 10.1016/j.devcel.2019.12.018

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    sciencedirect.com/science/article/pii/S1534580719310676
  182. www.sciencedirect.com www.sciencedirect.com
    Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice
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      AB_390722

      DOI: 10.1016/j.celrep.2020.107835

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  183. www.cell.com www.cell.com
    Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab
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      RRID:AB_390722

      DOI: 10.1016/j.celrep.2020.01.012

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    cell.com/cell-reports/abstract/S2211-1247(20)30021-8
  184. journals.physiology.org journals.physiology.org
    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes | American Journal of Physiology-Cell Physiology
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      RRID:AB_390722

      DOI: 10.1152/ajpcell.00148.2019

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  185. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies
    1
    1. scibot 03 Sep 2020
      RRID:AB_390722

      DOI: 10.1111/bph.14809

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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Environmental arginine controls multinuclear giant cell metabolism and formation
    1
    1. scibot 03 Sep 2020
      total S6K

      DOI: 10.1038/s41467-020-14285-1

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  187. journals.physiology.org journals.physiology.org
    A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics | American Journal of Physiology-Cell Physiology
    1
    1. scibot 01 Sep 2020
      RRID:AB_390722

      DOI: 10.1152/ajpcell.00383.2019

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  188. Aug 2020
  189. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Regulation of the 26S Proteasome
    1
    1. scibot 26 Aug 2020
      RRID:AB_39072

      DOI: 10.1016/j.celrep.2020.108059

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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model
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      RRID:AB_390722

      DOI: 10.1523/ENEURO.0097-19.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6565377/
  191. Jan 2020
  192. www.sciencedirect.com www.sciencedirect.com
    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
    1
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      RRID:AB_390722

      DOI: 10.1016/j.celrep.2019.07.084

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    sciencedirect.com/science/article/pii/S2211124719310009
  193. www.sciencedirect.com www.sciencedirect.com
    Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation
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      DOI: 10.1016/j.neuron.2019.07.011

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    sciencedirect.com/science/article/pii/S0896627319306373
  194. www.sciencedirect.com www.sciencedirect.com
    Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling
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      RRID:AB_390722

      DOI: 10.1016/j.chembiol.2019.11.014

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    sciencedirect.com/science/article/pii/S2451945619303964
  195. www.sciencedirect.com www.sciencedirect.com
    NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression
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    1. scibot 13 Jan 2020
      RRID:AB_390722

      DOI: 10.1016/j.celrep.2019.06.085

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    sciencedirect.com/science/article/pii/S2211124719308654
  196. www.jbc.org www.jbc.org
    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
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    Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures
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    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
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    Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2
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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
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    Lysosome Positioning Influences mTORC2 and AKT Signaling
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    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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    Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time
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  217. Nov 2018
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
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    Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin
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    In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver
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    Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability
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    The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine
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    Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat
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    mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance
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    Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice
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    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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    Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells
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    As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
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    Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
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  234. Nov 2017
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    mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
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    Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward
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