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Sep 2025
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ER stress tolerance is regulated by copper-dependent PERK kinase activity

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116318
  
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sciencedirect.com/science/article/pii/S2211124725010897
Jul 2025
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Ceftriaxone ameliorates tau phosphorylation and mislocalization in APP/PS1 AD mice by inhibiting endoplasmic reticulum stress

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  DOI: 10.1016/j.neuropharm.2025.110600
  
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sciencedirect.com/science/article/pii/S0028390825003089
Mar 2025
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Outer radial glia promotes white matter regeneration after neonatal brain injury

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  DOI: 10.1016/j.xcrm.2025.101986
  
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cell.com/cell-reports-medicine/abstract/S2666-3791(25)00059-X
Dec 2024
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DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways

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  DOI: 10.1016/j.celrep.2024.114984
  
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sciencedirect.com/science/article/pii/S2211124724013354
Sep 2024
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Macrophage NRF1 promotes mitochondrial protein turnover via the ubiquitin proteasome system to limit mitochondrial stress and inflammation

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sciencedirect.com/science/article/pii/S2211124724011318
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Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy

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  DOI: 10.1002/glia.24612
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24612
Apr 2024
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miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress

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  DOI: 10.1158/1541-7786.MCR-23-0676
  
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aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
Mar 2024
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Collective cell migration relies on PPP1R15-mediated regulation of the endoplasmic reticulum stress response

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sciencedirect.com/science/article/pii/S0960982224001568
Nov 2023
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RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.molcel.2023.10.012
  
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sciencedirect.com/science/article/pii/S1097276523008493
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Differential Ire1 determines loser cell fate in tumor-suppressive cell competition

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113303
  
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sciencedirect.com/science/article/pii/S2211124723013153
Oct 2023
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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

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  DOI: 10.1016/j.isci.2023.108082
  
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cell.com/iscience/abstract/S2589-0042(23)02159-4
May 2023
www.biorxiv.org www.biorxiv.org

FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis

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1. scibot 25 May 2023
  
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  DOI: 10.1101/2023.05.20.541585
  
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biorxiv.org/content/10.1101/2023.05.20.541585v1
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Piezo1 suppression reduces demyelination after... : Neural Regeneration Research

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1. scibot 06 May 2023
  
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  DOI: 10.4103/1673-5374.361531
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10154511/
Apr 2023
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Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression

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1. scibot 21 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.021
  
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sciencedirect.com/science/article/pii/S1535610823000946
Mar 2023
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Safety and efficacy of intraventricular immunovirotherapy with oncolytic HSV-1 for CNS cancers

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1. scibot 15 Mar 2023
  
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  DOI: 10.1158/1078-0432.CCR-22-1382
  
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aacrjournals.org/clincancerres/article/28/24/5419/711437/Safety-and-Efficacy-of-Intraventricular
Jan 2023
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Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging

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1. scibot 26 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.112042
  
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sciencedirect.com/science/article/pii/S2211124723000530
Dec 2022
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ccr-22-1382-html.html

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  DOI: 10.1158/1078-0432.CCR-22-1382
  
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52.53.155.43/6d2b403121fa025e13c6da7e664df49c19b35c74/ccr-22-1382-html.html
Nov 2022
rupress.org rupress.org

V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

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1. scibot 03 Nov 2022
  
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  DOI: 10.1083/jcb.202205045
  
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rupress.org/jcb/article/222/1/e202205045/213623/V-ATPase-TORC1-mediated-ATFS-1-translation-directs
Sep 2022
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Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction

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1. scibot 09 Sep 2022
  
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  DOI: 10.3389/fragi.2022.975129
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9450999/
May 2022
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Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module

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  DOI: 10.1016/j.isci.2022.104282
  
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sciencedirect.com/science/article/pii/S2589004222005521
Mar 2022
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Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication

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  DOI: 10.1016/j.molcel.2022.02.031
  
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sciencedirect.com/science/article/pii/S1097276522002052
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PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen

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1. scibot 17 Mar 2022
  
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  DOI: 10.1084/jem.20211498
  
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rupress.org/jem/article/219/4/e20211498/213062/PERK-reprograms-hematopoietic-progenitor-cells-to
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The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

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sciencedirect.com/science/article/pii/S1550413122000547
Jan 2022
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Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection

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  DOI: 10.1371/journal.pntd.0009192
  
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journals.plos.org/plosntds/article
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Clusterin is involved in mediating the metabolic function of adipose SIRT1

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  DOI: 10.1016/j.isci.2021.103709
  
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sciencedirect.com/science/article/pii/S2589004221016795
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Cytosolic adaptation to mitochondria-induced proteostatic stress causes progressive muscle wasting

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sciencedirect.com/science/article/pii/S2589004221016850
Nov 2021
elifesciences.org elifesciences.org

mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion

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1. scibot 24 Nov 2021
  
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  DOI: 10.7554/eLife.69015
  
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elifesciences.org/articles/69015
Aug 2021
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Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy

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Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

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Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

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sciencedirect.com/science/article/pii/S155041311830192X
elifesciences.org elifesciences.org

Untitled document

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  DOI: 10.7554/eLife.22871
  
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elifesciences.org/articles/22871
Jul 2021
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Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence

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  DOI: 10.1016/j.devcel.2021.06.009
  
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sciencedirect.com/science/article/pii/S1534580721005165
Jun 2021
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Pumilio2 and Staufen2 selectively balance the synaptic proteome

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1. scibot 23 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109279
  
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sciencedirect.com/science/article/pii/S221112472100646X
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21

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1. scibot 22 May 2021
  
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  Anti-phosphorylated eIF2α serine 51 (Rabbit monoclonal)
  
  DOI: 10.7554/eLife.66519
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8128440/
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Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.05.007
  
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A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation

1
1. scibot 01 May 2021
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.cmet.2021.01.013
  
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sciencedirect.com/science/article/pii/S1550413121000139
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Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism

1
1. scibot 30 Apr 2021
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.cmet.2020.11.009
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7858244/
Mar 2021
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Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models

1
1. scibot 18 Mar 2021
  
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  RRID:AB_390740
  
  DOI: 10.1007/s00204-021-03011-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7961173/
Sep 2020
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ATF4-Induced Warburg Metabolism Drives Over-Proliferation in Drosophila

1
1. scibot 17 Sep 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.celrep.2020.107659
  
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sciencedirect.com/science/article/pii/S2211124720306124
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Dietary Adaptation of Microbiota in Drosophila Requires NF-κB-Dependent Control of the Translational Regulator 4E-BP

1
1. scibot 16 Sep 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.celrep.2020.107736
  
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ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

1
1. scibot 13 Sep 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.cmet.2020.03.008
  
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sciencedirect.com/science/article/pii/S1550413120301236
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Evolutionarily Conserved Regulation of Sleep by the Protein Translational Regulator PERK

1
1. scibot 04 Sep 2020
  
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  Rabbit anti-phospho-eIF2α (Ser51)
  
  DOI: 10.1016/j.cub.2020.02.030
  
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sciencedirect.com/science/article/pii/S0960982220302037
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Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy

1
1. scibot 03 Sep 2020
  
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  phospho-eIF2α (Ser51)
  
  DOI: 10.1038/s41419-020-2642-6
  
  Resource: (Cell Signaling Technology Cat# 3597, RRID:AB_390740)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_390740
  
  Curator comments: Rabbit Anti-eIF2alpha, phospho (Ser51) Monoclonal Antibody, Unconjugated, Clone 119A11 Cell Signaling Technology Cat# 3597
  
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nature.com/articles/s41419-020-2642-6
Jan 2020
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The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.neuron.2019.08.007
  
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sciencedirect.com/science/article/pii/S0896627319306919
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Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.cmet.2019.08.021
  
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sciencedirect.com/science/article/pii/S1550413119304954
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NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.celrep.2019.10.053
  
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sciencedirect.com/science/article/pii/S2211124719313671
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1111/bph.14713
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14713
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Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.neuron.2019.12.014
  
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sciencedirect.com/science/article/pii/S0896627319310566
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.7554/eLife.39578
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6426440/
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Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.ccell.2019.01.018
  
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sciencedirect.com/science/article/pii/S1535610819300522
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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

1
1. scibot 12 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.immuni.2019.03.005
  
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sciencedirect.com/science/article/pii/S1074761319300950
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Tracing MYC Expression for Small Molecule Discovery

1
1. scibot 12 Jan 2020
  
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  RRID:AB_390740
  
  DOI: 10.1016/j.chembiol.2019.02.007
  
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sciencedirect.com/science/article/pii/S245194561930042X
Nov 2018
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The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis

1
1. scibot 05 Nov 2018
  
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  RRID:AB_390740
  
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sciencedirect.com/science/article/pii/S0960982218303038
www.jneurosci.org www.jneurosci.org

Endoplasmic reticulum stress contributes to the loss of newborn hippocampal neurons after traumatic brain injury

1
1. scibot 05 Nov 2018
  
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  RRID:AB_390740
  
  Curator: @bandrow
  
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jneurosci.org/content/38/9/2372
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Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase

1
1. scibot 05 Nov 2018
  
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  RRID:AB_390740
  
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sciencedirect.com/science/article/pii/S153561081730555X
Nov 2017
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The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

1
1. scibot 08 Nov 2017
  
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  RRID:AB_390740
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1097276517305798
academic.oup.com academic.oup.com

Guanabenz Sensitizes Pancreatic β Cells to Lipotoxic Endoplasmic Reticulum Stress and Apoptosis

1
1. scibot 08 Nov 2017
  
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  AB_390740
  
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academic.oup.com/endo/article/158/6/1659/3058741/Guanabenz-Sensitizes-Pancreatic-Cells-to-Lipotoxic
elifesciences.org elifesciences.org

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

1
1. scibot 08 Nov 2017
  
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  AB_390740
  
  Curator: @kaitlinsung
  
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elifesciences.org/content/6/e22871
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Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes

1
1. scibot 08 Nov 2017
  
  in Public
  
  3597
  
  Curator: @gabimpine
  
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  (Cell Signaling Technology Cat# 3597, RRID:AB_390740)
  
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sciencedirect.com/science/article/pii/S1550413117301705