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Apr 2026
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An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment

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1. scibot 29 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.04.001
  
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sciencedirect.com/science/article/pii/S107476132600141X
Jan 2026
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Controlled pyroptosis of engineered macrophages enables biphasic antitumor via the release of oncolytic bacteria and inflammatory signals

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1. scibot 30 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116918
  
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sciencedirect.com/science/article/pii/S2211124725016900
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Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity

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1. scibot 16 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.018
  
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cell.com/cancer-cell/fulltext/S1535-6108(25)00552-5
Dec 2025
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Gut microbiota promotes immune tolerance at the maternal-fetal interface

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1. scibot 18 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.022
  
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sciencedirect.com:5037/science/article/pii/S0092867425013182
Oct 2025
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CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1

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1. scibot 08 Oct 2025
  
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sciencedirect.com/science/article/pii/S266637912500480X
Aug 2025
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells

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1. scibot 01 Aug 2025
  
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sciencedirect.com/science/article/pii/S1074761325003176
Jul 2025
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PARP1-NFATc1-PD1 pathway of maturation and stability of CD8+T cells is beneficial against chronic Trypanosoma cruzi infection

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1. scibot 08 Jul 2025
  
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sciencedirect.com/science/article/pii/S2589004225011873
Jun 2025
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Gut microbiota dysbiosis induced by brain tumors modulates the efficacy of immunotherapy

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115825
  
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sciencedirect.com/science/article/pii/S2211124725005960
Mar 2025
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Microbiota-produced immune regulatory bile acid metabolites control central nervous system autoimmunity

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102028
  
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sciencedirect.com/science/article/pii/S2666379125001016
Feb 2025
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PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.stem.2025.01.010
  
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sciencedirect.com/science/article/pii/S1934590925000104
Sep 2024
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Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.019
  
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sciencedirect.com/science/article/pii/S1535610824003180
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Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2019.07.047
  
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sciencedirect.com/science/article/pii/S2211124719309519
Mar 2024
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ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113995
  
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sciencedirect.com/science/article/pii/S2211124724003231
Feb 2024
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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113797
  
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sciencedirect.com/science/article/pii/S2211124724001256
Dec 2023
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MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy

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1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113452
  
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sciencedirect.com/science/article/pii/S221112472301464X
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Comparing HD knockin pigs and mice reveals the pathological role of IL-17

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1. scibot 01 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113443
  
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sciencedirect.com/science/article/pii/S2211124723014559
Oct 2023
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Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

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1. scibot 26 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101234
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10591062/
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Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113220
  
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sciencedirect.com/science/article/pii/S2211124723012329
Apr 2023
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Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

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1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.stem.2023.03.016
  
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sciencedirect.com/science/article/pii/S1934590923000875
Mar 2023
europepmc.org europepmc.org

Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma

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1. scibot 25 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.03.004
  
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europepmc.org/article/med/36963400
Feb 2023
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Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2

1
1. scibot 17 Feb 2023
  
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sciencedirect.com/science/article/pii/S2589004223002031
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XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections

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1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112123
  
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sciencedirect.com/science/article/pii/S2211124723001341
Dec 2022
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Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111797
  
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sciencedirect.com/science/article/pii/S2211124722016850
Sep 2022
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BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis

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1. scibot 24 Sep 2022
  
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  DOI: 10.1038/s41598-022-20017-w
  
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nature.com/articles/s41598-022-20017-w
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PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

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1. scibot 02 Sep 2022
  
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  DOI: 10.1158/2159-8290.CD-21-0694
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
Aug 2022
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Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis

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1. scibot 12 Aug 2022
  
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  DOI: 10.1016/j.chom.2022.07.003
  
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sciencedirect.com/science/article/pii/S1931312822003493
Jul 2022
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Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.immuni.2022.06.020
  
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sciencedirect.com/science/article/pii/S107476132200293X
Jun 2022
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Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.chembiol.2022.05.012
  
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sciencedirect.com/science/article/pii/S2451945622002045
May 2022
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STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

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1. scibot 26 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110838
  
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sciencedirect.com/science/article/pii/S2211124722006118
Mar 2022
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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

1
1. scibot 26 Mar 2022
  
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  DOI: 10.1016/j.molcel.2022.02.033
  
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sciencedirect.com/science/article/pii/S1097276522002076
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Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages

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1. scibot 03 Mar 2022
  
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  DOI: 10.7554/eLife.69982
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8860447/
Nov 2021
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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109911
  
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sciencedirect.com/science/article/pii/S221112472101384X
Oct 2021
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Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma

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1. scibot 08 Oct 2021
  
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  DOI: 10.1016/j.isci.2021.103163
  
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sciencedirect.com/science/article/pii/S2589004221011317
Aug 2021
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Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells

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1. scibot 14 Aug 2021
  
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  DOI: 10.1016/j.ccell.2019.01.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6645919/
May 2021
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Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology

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1. scibot 28 May 2021
  
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  DOI: 10.1126/sciadv.abe4601
  
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NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes

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1. scibot 26 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109176
  
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MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

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  DOI: 10.1016/j.immuni.2021.02.015
  
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Mar 2021
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Functional characterization of the dural sinuses as a neuroimmune interface

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  DOI: 10.1016/j.cell.2020.12.040
  
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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.immuni.2018.12.020
  
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Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal

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cell.com/cell-systems/abstract/S2405-4712(20)30455-5
Dec 2020
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SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity

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1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.celrep.2020.108468
  
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Sep 2020
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Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition

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  DOI: 10.1016/j.chom.2020.04.008
  
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The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.chom.2020.04.024
  
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Jan 2020
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Untitled document

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  DOI: 10.1016/j.immuni.2018.12.020
  
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Untitled document

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  DOI: 10.1016/j.ccell.2019.01.002
  
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Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.03.004
  
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Nov 2018
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Untitled document

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The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

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Untitled document

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Nov 2017
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Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection

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1. scibot 08 Nov 2017
  
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The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells

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