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The scavenger receptor MARCO is a ligand for the immune inhibitory receptor LAIR-1 and regulates its function in cis

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1. scibot 14 Dec 2025
  
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  DOI: 10.1126/scisignal.ado2768
  
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science.org/doi/10.1126/scisignal.ado2768
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neutrophil Dynamics Contribute to Disease Progression and Poor Survival in Pancreatic Cancer

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1. scibot 20 Nov 2025
  
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  DOI: 10.3390/cancers17213541
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12607450/
Oct 2025
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Phocaeicola vulgatus induces immunotherapy resistance in hepatocellular carcinoma via reducing indoleacetic acid production

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102370
  
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sciencedirect.com/science/article/pii/S2666379125004434
Sep 2025
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Monocyte/macrophage-derived interleukin-15 mediates the pro-inflammatory phenotype of CD226+ B cells in type 1 diabetes

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1. scibot 19 Sep 2025
  
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  DOI: 10.1016/j.ebiom.2025.105946
  
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sciencedirect.com/science/article/pii/S2352396425003901
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1-s2.0-S2589004225017985-main-html.html

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1. scibot 16 Sep 2025
  
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52.53.155.43/bfa103a56e03ca8260532bade686a824030c14b2/1-s2.0-S2589004225017985-main-html.html
Aug 2025
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Protocol to develop a 3D mouse autologous lung tumor-immune spheroid co-culture model to advance radiotherapy-based treatments

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.xpro.2025.104021
  
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sciencedirect.com/science/article/pii/S2666166725004277
Jul 2025
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.018
  
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cell.com/cell/fulltext/S0092-8674(25)00684-1
May 2025
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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.032
  
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sciencedirect.com/science/article/pii/S0092867425005021
Apr 2025
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Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity

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1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.02.029
  
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sciencedirect.com/science/article/pii/S0092867425002569
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Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.017
  
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sciencedirect.com/science/article/pii/S0092867425002909
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Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.immuni.2025.03.004
  
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sciencedirect.com/science/article/pii/S1074761325001232
Mar 2025
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DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115364
  
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sciencedirect.com/science/article/pii/S2211124725001354
Dec 2024
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CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells

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1. scibot 05 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101844
  
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sciencedirect.com/science/article/pii/S2666379124006153
Nov 2024
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Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.immuni.2024.10.013
  
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sciencedirect.com/science/article/pii/S107476132400493X
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A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114891
  
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sciencedirect.com/science/article/pii/S2211124724012427
Sep 2024
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Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.immuni.2024.08.015
  
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sciencedirect.com/science/article/pii/S1074761324004151
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PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ymthe.2024.05.038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405166/
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Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.029
  
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sciencedirect.com/science/article/pii/S0092867424009565
Aug 2024
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Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

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1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.010
  
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sciencedirect.com/science/article/pii/S1074761324003595
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The guanine nucleotide exchange factor Rin-like controls Tfh cell differentiation via CD28 signaling

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1. scibot 16 Mar 2024
  
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  DOI: 10.1084/jem.20221466
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10499045/
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Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113929
  
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  DOI: 10.1016/j.celrep.2024.113929
  
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sciencedirect.com/science/article/pii/S2211124724002572
Feb 2024
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Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

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1. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.011
  
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2. scibot 14 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.011
  
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sciencedirect.com/science/article/pii/S1074761324000360
Jan 2024
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Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling

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1. scibot 25 Jan 2024
  
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  DOI: 10.1126/sciadv.adi2012
  
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2. scibot 23 Jan 2024
  
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  DOI: 10.1126/sciadv.adi2012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
Oct 2023
www.embopress.org www.embopress.org

Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis

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1. scibot 21 Oct 2023
  
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  DOI: 10.15252/embr.202357653
  
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embopress.org/doi/10.15252/embr.202357653
Sep 2023
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Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.cmet.2023.08.010
  
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sciencedirect.com/science/article/pii/S1550413123003315
May 2023
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Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.isci.2023.106758
  
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sciencedirect.com/science/article/pii/S2589004223008350
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Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.isci.2023.106774
  
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sciencedirect.com/science/article/pii/S2589004223008519
Apr 2023
www.cell.com www.cell.com

Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.03.011
  
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cell.com/cell/fulltext/S0092-8674(23)00271-4
Mar 2023
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Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

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1. scibot 10 Mar 2023
  
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  DOI: 10.1016/j.cmet.2023.02.013
  
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sciencedirect.com/science/article/pii/S1550413123000499
Nov 2022
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The quality of energy- and macronutrient-balanced diets regulates host susceptibility to influenza in mice

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111638
  
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sciencedirect.com/science/article/pii/S2211124722015091
Sep 2022
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Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal

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1. scibot 03 Sep 2022
  
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  DOI: 10.1016/j.stem.2022.08.008
  
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sciencedirect.com/science/article/pii/S1934590922003447
Jul 2022
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Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.ccell.2022.06.011
  
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sciencedirect.com/science/article/pii/S1535610822002756
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B cell-mediated regulatory mechanisms control tumor-promoting intestinal inflammation

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111051
  
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sciencedirect.com/science/article/pii/S2211124722008452
Jun 2022
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Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes

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1. scibot 29 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.111011
  
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Targeted deletion of Interleukin-3 results in asthma exacerbations

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Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis

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STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program

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Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse

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Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer

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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages

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T-cell–derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2

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Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua

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Human gut bacterial metabolism drives Th17 activation and colitis

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Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma

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Untitled document

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T-cell–derived extracellular vesicles regulate B-cell IgG production via pyruvate kinase muscle isozyme 2

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Loss of HDAC6 alters gut microbiota and worsens obesity | The FASEB Journal

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Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells

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Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation

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Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells

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Therapeutic efficacy of pulmonary live tuberculosis vaccines against established asthma by subverting local immune environment

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Increased demand for NAD+ relative to ATP drives aerobic glycolysis

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Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism

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Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure

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PP2AC Phospho-Tyr307 Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2AC Modifications Including Leu309 Methylation

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A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

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Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids

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Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses

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Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy

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Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor

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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

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The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells

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The Bone Marrow Protects and Optimizes Immunological Memory during Dietary Restriction

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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

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Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2018.12.024
  
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sciencedirect.com/science/article/pii/S1074761318305727
Nov 2018
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A Functionally Defined In Vivo Astrocyte Population Identified by c-Fos Activation in a Mouse Model of Multiple Sclerosis Modulated by S1P Signaling: Immediate-Early Astrocytes (ieAstrocytes)

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6153337/
Nov 2017
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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

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A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

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1. scibot 08 Nov 2017
  
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Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments

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1. scibot 08 Nov 2017
  
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