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Anti–B-cell maturation antigen chimeric antigen receptor T-cell therapy bb21217 for relapsed and refractory multiple myeloma: results from the phase 1 CRB-402 study

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  DOI: 10.1158/2326-6066.CIR-24-0527
  
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aacrjournals.org/cancerimmunolres/article/14/4/528/776517/Anti-B-cell-Maturation-Antigen-Chimeric-Antigen
Jun 2025
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iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102195
  
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sciencedirect.com/science/article/pii/S266637912500268X
Mar 2025
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ACVR2A attenuation impacts lactate production and hyperglycolytic conditions attracting regulatory T cells in hepatocellular carcinoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102038
  
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sciencedirect.com/science/article/pii/S2666379125001119
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Trajectories of microbiome-derived bile acids in early life – insights into the progression to islet autoimmunity

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1. scibot 21 Mar 2025
  
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  DOI: 10.1101/2025.02.18.25322275
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11888530/
Feb 2025
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Acidic pH can attenuate immune killing through inactivation of perforin

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1. scibot 27 Feb 2025
  
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  DOI: 10.1038/s44319-024-00365-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11850619/
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Systems immunology analysis of human immune organoids identifies host-specific correlates of protection to different influenza vaccines

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.stem.2025.01.014
  
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sciencedirect.com/science/article/pii/S1934590925000141
Nov 2024
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High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111166
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11550119/
Sep 2024
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Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potential

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1. scibot 18 Sep 2024
  
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  DOI: 10.1007/s00018-024-05429-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11393232/
Aug 2024
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Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8+ T cell responses

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1. scibot 02 Aug 2024
  
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  DOI: 10.1126/sciadv.adl1122
  
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science.org/doi/10.1126/sciadv.adl1122
Jul 2024
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Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.05.010
  
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cell.com/cell-stem-cell/abstract/S1934-5909(24)00207-8
Apr 2024
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Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells

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1. scibot 26 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101526
  
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sciencedirect.com/science/article/pii/S2666379124001952
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8+ T cell responses

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1. scibot 09 Mar 2024
  
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  DOI: 10.1126/sciadv.adl1122
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10917340/
Jan 2024
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Inosine induces stemness features in CAR-T cells and enhances potency

1
1. scibot 26 Jan 2024
  
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  DOI: 10.1016/j.ccell.2024.01.002
  
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sciencedirect.com/science/article/pii/S1535610824000084
www.nature.com www.nature.com

MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

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1. scibot 25 Jan 2024
  
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  DOI: 10.1038/s41467-023-44460-z
  
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nature.com/articles/s41467-023-44460-z
Dec 2023
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AA2P-mediated DNA demethylation synergizes with stem cell agonists to promote expansion of hematopoietic stem cells

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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2. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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3. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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sciencedirect.com/science/article/pii/S2667237523003405
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PIM kinases regulate early human Th17 cell differentiation

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1. scibot 02 Dec 2023
  
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  DOI: 10.1016/j.celrep.2023.113469
  
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sciencedirect.com/science/article/pii/S221112472301481X
Sep 2023
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Redirector of Vaccine-induced Effector Responses (RoVER) for specific killing of cellular targets

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1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.ebiom.2023.104785
  
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sciencedirect.com/science/article/pii/S2352396423003511
Aug 2023
www.biorxiv.org www.biorxiv.org

Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses

1
1. scibot 28 Aug 2023
  
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  DOI: 10.1101/2023.08.19.553954
  
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biorxiv.org/content/10.1101/2023.08.19.553954v1
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells

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1. scibot 12 Aug 2023
  
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  AB_395879
  
  DOI: 10.3389/fimmu.2023.1107397
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10407399/
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Robust SARS-CoV-2 T cell responses with common TCRαβ motifs towards COVID-19 vaccines in haematological malignancy patients impacting B cell immunity

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1. scibot 12 Apr 2023
  
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  DOI: 10.1016/j.xcrm.2023.101017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10040362/
Mar 2023
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Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells

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1. scibot 04 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112193
  
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sciencedirect.com/science/article/pii/S2211124723002048
Dec 2022
link.springer.com link.springer.com

Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites

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1. scibot 06 Dec 2022
  
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  DOI: 10.1007/s00262-022-03325-y
  
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link.springer.com/article/10.1007/s00262-022-03325-y
Oct 2022
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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.immuni.2022.09.014
  
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sciencedirect.com/science/article/pii/S1074761322005088
Sep 2022
rupress.org rupress.org

SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity

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1. scibot 16 Sep 2022
  
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  DOI: 10.1084/jem.20220780
  
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rupress.org/jem/article/219/10/e20220780/213399/SARS-CoV-2-breakthrough-infection-in-vaccinees
Jun 2022
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SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection

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1. scibot 25 Jun 2022
  
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  DOI: 10.1016/j.immuni.2022.06.003
  
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sciencedirect.com/science/article/pii/S1074761322002412
Mar 2022
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML

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1. scibot 09 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110481
  
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sciencedirect.com/science/article/pii/S2211124722002145
Jan 2022
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The endothelial diapedesis synapse regulates transcellular migration of human T lymphocytes in a CX3CL1- and SNAP23-dependent manner

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1. scibot 19 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110243
  
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sciencedirect.com/science/article/pii/S2211124721017526
Dec 2021
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Hydroxychloroquine inhibits the mitochondrial antioxidant system in activated T cells

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103509
  
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sciencedirect.com/science/article/pii/S2589004221014802
Oct 2021
academic.oup.com academic.oup.com

The impact of long-term physical inactivity on adipose tissue immunometabolism

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1. scibot 01 Oct 2021
  
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  DOI: 10.1210/clinem/dgab647
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab647/6364151
Aug 2021
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Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109525
  
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sciencedirect.com/science/article/pii/S2211124721009566
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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  DOI: 10.1016/j.celrep.2018.10.074
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6371971/
Jul 2021
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Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells

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1. scibot 28 Jul 2021
  
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  DOI: 10.1016/j.celrep.2018.10.074
  
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sciencedirect.com/science/article/pii/S2211124718316784
May 2021
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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.11.001
  
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sciencedirect.com/science/article/pii/S1934590920305397
Apr 2021
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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells

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1. scibot 29 Apr 2021
  
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  DOI: 10.1016/j.cmet.2020.07.008
  
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sciencedirect.com/science/article/pii/S1550413120303661
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrated immune dynamics define correlates of COVID-19 severity and antibody responses

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1. scibot 02 Mar 2021
  
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  DOI: 10.1016/j.xcrm.2021.100208
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7862905/
Feb 2021
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Peptides Derived From Insulin Granule Proteins are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice.

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  DOI: 10.2337/db20-0013
  
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Sep 2020
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Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells

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Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases

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The Interplay between CD27dull and CD27bright B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory

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Jan 2020
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Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

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Maturation of the Human Intestinal Immune System Occurs Early in Fetal Development

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Untitled document

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  DOI: 10.1016/j.immuni.2019.03.014
  
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Nov 2018
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Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance

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Conventional and Neo-Antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors

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Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity

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Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota

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Untitled document

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Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis

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