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Dietary ω−3 polyunsaturated fatty acids (PUFAs) reduce cholesterol-driven non-small cell lung cancer (NSCLC) progression in mouse models of disease

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nature.com/articles/s43856-025-01193-y
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids

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  DOI: 10.1158/2326-6066.CIR-23-1011
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11790382/
May 2025
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Distinct viral reservoirs and immune signatures in individuals on long-term antiretroviral therapy with perinatally acquired HIV-1

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1. scibot 31 May 2025
  
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  DOI: 10.1016/j.xcrm.2025.102150
  
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sciencedirect.com/science/article/pii/S266637912500223X
Mar 2025
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Integrated computational analysis identifies therapeutic targets with dual action in cancer cells and T cells

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sciencedirect.com/science/article/pii/S107476132500072X
Feb 2025
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Potentiating anti-tumor immunity by re-engaging immune synapse molecules

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sciencedirect.com/science/article/pii/S2666379125000485
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Hybrid immunity-based induction of durable pan-endemic-coronavirus immunity in the elderly

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  DOI: 10.1016/j.celrep.2025.115314
  
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sciencedirect.com/science/article/pii/S2211124725000853
Jan 2025
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Interferon-α promotes HLA-B-restricted presentation of conventional and alternative antigens in human pancreatic β-cells

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1. scibot 23 Jan 2025
  
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  DOI: 10.1038/s41467-025-55908-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11748642/
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SHMT2 regulates CD8+ T cell senescence via the reactive oxygen species axis in HIV-1 infected patients on antiretroviral therapy

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.ebiom.2024.105533
  
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sciencedirect.com/science/article/pii/S2352396424005693
Dec 2024
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ssrn-5035905-html.html

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1. scibot 06 Dec 2024
  
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52.53.155.43/e64f14dc3220054f5f79a6a960474479f277202c/ssrn-5035905-html.html
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CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells

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  DOI: 10.1016/j.xcrm.2024.101844
  
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sciencedirect.com/science/article/pii/S2666379124006153
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin facilitates viral reservoir reactivation and their recognition by anti-HIV-1 envelope antibodies

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1. scibot 12 Sep 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11381840/
Jul 2024
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IRF4 impedes human CD8 T cell function and promotes cell proliferation and PD-1 expression

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1. scibot 23 Jul 2024
  
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sciencedirect.com/science/article/pii/S2211124724007290
Apr 2024
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The immune suppressor IGSF1 as a potential target for cancer immunotherapy

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  DOI: 10.1158/2326-6066.CIR-23-0817
  
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aacrjournals.org/cancerimmunolres/article/12/4/491/741941/The-Immune-Suppressor-IGSF1-as-a-Potential-Target
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DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma

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  DOI: 10.1016/j.xcrm.2024.101469
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10983114/
Mar 2024
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Post-pandemic memory T cell response to SARS-CoV-2 is durable, broadly targeted, and cross-reactive to the hypermutated BA.2.86 variant

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  DOI: 10.1016/j.chom.2023.12.003
  
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sciencedirect.com/science/article/pii/S1931312823004985
Feb 2024
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Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin’s lymphoma

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sciencedirect.com/science/article/pii/S2666379124000375
Dec 2023
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Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108728
  
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sciencedirect.com/science/article/pii/S2589004223028055
Nov 2023
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Immunosuppressive low-density neutrophils in the blood of cancer patients display a mature phenotype

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  DOI: 10.26508/lsa.202302332
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10628041/
Sep 2023
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Systemic immune profiling of Omicron-infected subjects inoculated with different doses of inactivated virus vaccine

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  DOI: 10.1016/j.cell.2023.08.033
  
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sciencedirect.com/science/article/pii/S0092867423009649
Aug 2023
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

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sciencedirect.com/science/article/pii/S1074761323003278
Jun 2023
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Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4+ T cells

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  DOI: 10.1016/j.celrep.2023.112634
  
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sciencedirect.com/science/article/pii/S2211124723006459
May 2023
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Proteomics of immune cells from liver tumors reveals immunotherapy targets

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  DOI: 10.1016/j.xgen.2023.100331
  
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Apr 2023
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Evolution of long-term vaccine induced and hybrid immunity in healthcare workers after different COVID19 vaccine regimens: a longitudinal cohort study

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  DOI: 10.1016/j.medj.2023.02.004
  
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sciencedirect.com/science/article/pii/S2666634023000648
Feb 2023
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One-step CRISPR-Cas9-mediated knockout of native TCRαβ genes in human T cells using RNA electroporation

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  DOI: 10.1016/j.xpro.2023.102112
  
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sciencedirect.com/science/article/pii/S2666166723000709
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Effects of tuberculosis and/or HIV-1 infection on COVID-19 presentation and immune response in Africa

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  DOI: 10.1038/s41467-022-35689-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9836341/
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Impact of SARS-CoV-2 exposure history on the T cell and IgG response

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  DOI: 10.1016/j.xcrm.2022.100898
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9771741/
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CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy

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  DOI: 10.1016/j.xcrm.2022.100878
  
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sciencedirect.com/science/article/pii/S2666379122004426
Dec 2022
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Anti-CD73 antibody activates human B cells, enhances humoral responses and induces redistribution of B cells in patients with cancer

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  DOI: 10.1136/jitc-2022-005802
  
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jitc.bmj.com/content/10/12/e005802
Jul 2022
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Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery

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  DOI: 10.1016/j.xcrm.2022.100697
  
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sciencedirect.com/science/article/pii/S2666379122002336
Jun 2022
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Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity

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  DOI: 10.1016/j.xcrm.2022.100660
  
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sciencedirect.com/science/article/pii/S2666379122001926
Mar 2022
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The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

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  DOI: 10.1016/j.cmet.2022.02.010
  
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sciencedirect.com/science/article/pii/S1550413122000547
Feb 2022
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Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants

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  DOI: 10.1016/j.isci.2022.103810
  
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  DOI: 10.1016/j.isci.2022.103810
  
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sciencedirect.com/science/article/pii/S2589004222000803
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

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  DOI: 10.1016/j.cell.2021.12.040
  
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SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans

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Inhibition of RFX6 Suppresses the Invasive Ability of Tumor Cells Through the Notch Pathway and Affects Tumor Immunity in Hepatocellular Carcinoma

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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner

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Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine

1
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IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cells

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PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

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T cell stiffness is enhanced upon formation of immunological synapse

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Untitled document

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CD16‐158‐Valine Chimeric Receptor T Cells Overcome the Resistance of Kras‐Mutated Colorectal Carcinoma Cells to Cetuximab

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1. scibot 30 Jul 2021
  
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  CD28
  
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The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

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Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells

1
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Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells

1
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CD27−CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression

1
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CD101 genetic variants modify regulatory and conventional T cell phenotypes and functions

1
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Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics

1
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Double-Edged Sword: Interleukin-2 Promotes T Regulatory Cell Differentiation but Also Expands Interleukin-13- and Interferon-γ-Producing CD8+ T Cells via STAT6-GATA-3 Axis in Systemic Lupus Erythematosus

1
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A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs

1
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THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells

1
1. scibot 10 Sep 2020
  
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Age-Related Dopaminergic Innervation Augments T Helper 2-Type Allergic Inflammation in the Postnatal Lung

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MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells

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Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

1
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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

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cell.com/cell-reports/fulltext/S2211-1247(19)30571-6
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Untitled document

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Untitled document

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Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection

1
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Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape

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Cladribine Exposure Results in a Sustained Modulation of the Cytokine Response in Human Peripheral Blood Mononuclear Cells

1
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L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

3
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