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Scalable generation of hematopoietic stem cell-engineered off-the-shelf mono-specific cytotoxic T cells targeting solid tumors

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1. scibot 20 Aug 2026
  
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  DOI: 10.1016/j.xcrm.2026.102998
  
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sciencedirect.com/science/article/pii/S2666379126004155
May 2026
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Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML

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1. scibot 08 May 2026
  
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  DOI: 10.1016/j.stem.2026.04.012
  
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sciencedirect.com/science/article/pii/S1934590926001529
Aug 2025
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Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.medj.2025.100804
  
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sciencedirect.com/science/article/pii/S2666634025002314
Jun 2025
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Lactate regulates cell differentiation of erythroid progenitor cells via histone lactylation modification

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112842
  
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sciencedirect.com/science/article/pii/S2589004225011034
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Senescence-resistant human mesenchymal progenitor cells counter aging in primates

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1. scibot 14 Jun 2025
  
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  DOI: 10.1016/j.cell.2025.05.021
  
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sciencedirect.com/science/article/pii/S0092867425005719
May 2025
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Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115671
  
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sciencedirect.com/science/article/pii/S2211124725004425
Jan 2025
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Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture

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1. scibot 31 Jan 2025
  
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  DOI: 10.1038/s41596-024-01077-w
  
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nature.com/articles/s41596-024-01077-w
Sep 2024
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Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis

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1. scibot 18 Sep 2024
  
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  DOI: 10.1186/s12951-024-02795-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11391629/
Jul 2024
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Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.06.009
  
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2. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.06.009
  
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cell.com/cell-stem-cell/abstract/S1934-5909(24)00217-0
Apr 2024
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Identification of cells of leukemic stem cell origin with non-canonical regenerative properties

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.xcrm.2024.101485
  
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sciencedirect.com/science/article/pii/S2666379124001319
Mar 2024
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Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis

3
1. scibot 14 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113918
  
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2. scibot 14 Mar 2024
  
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3. scibot 14 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113918
  
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sciencedirect.com/science/article/pii/S2211124724002468
Feb 2024
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Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

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1. scibot 18 Feb 2024
  
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  DOI: 10.1016/j.scr.2024.103348
  
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sciencedirect.com/science/article/pii/S1873506124000461
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Schisandrin B promotes hepatic differentiation from human umbilical cord mesenchymal stem cells

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108912
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844828/
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A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells

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1. scibot 01 Feb 2024
  
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  DOI: 10.1098/rsob.230407
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10805602/
Jan 2024
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Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing

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1. scibot 25 Jan 2024
  
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  DOI: 10.1016/j.celrep.2024.113704
  
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2. scibot 25 Jan 2024
  
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  DOI: 10.1016/j.celrep.2024.113704
  
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sciencedirect.com/science/article/pii/S2211124724000329
Dec 2023
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AA2P-mediated DNA demethylation synergizes with stem cell agonists to promote expansion of hematopoietic stem cells

3
1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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2. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.crmeth.2023.100663
  
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3. scibot 17 Dec 2023
  
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  RRID:AB_396151
  
  DOI: 10.1016/j.crmeth.2023.100663
  
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sciencedirect.com/science/article/pii/S2667237523003405
Oct 2023
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Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design

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1. scibot 11 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107952
  
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2. scibot 01 Oct 2023
  
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  DOI: 10.1016/j.isci.2023.107952
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10558812/
Aug 2023
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Early activation of inflammatory pathways in UBA1-mutated hematopoietic stem and progenitor cells in VEXAS

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.xcrm.2023.101160
  
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sciencedirect.com/science/article/pii/S2666379123003130
Apr 2023
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SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106621
  
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sciencedirect.com/science/article/pii/S2589004223006983
Aug 2022
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Off-The-Shelf Third-Party HSC-Engineered iNKT Cells for Ameliorating GvHD While Preserving GvL Effect in the Treatment of Blood Cancers

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1. scibot 17 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104859
  
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sciencedirect.com/science/article/pii/S2589004222011312
academic.oup.com academic.oup.com

Teprotumumab divergently alters fibrocyte gene expression: Implications for thyroid-associated ophthalmopathy

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1. scibot 13 Aug 2022
  
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  RRID:AB_396151
  
  DOI: 10.1210/clinem/dgac415
  
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academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgac415/6638970
May 2022
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Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging

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1. scibot 26 May 2022
  
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  DOI: 10.1016/j.devcel.2022.05.004
  
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sciencedirect.com/science/article/pii/S153458072200332X
Mar 2022
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Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function

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1. scibot 15 Mar 2022
  
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  DOI: 10.1016/j.stem.2022.02.010
  
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sciencedirect.com/science/article/pii/S1934590922000613
Nov 2021
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Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy

1
1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.xcrm.2021.100449
  
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sciencedirect.com/science/article/pii/S2666379121003177
Sep 2021
link.springer.com link.springer.com

Methods for Studying Mouse and Human Invariant Natural Killer T Cells

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1. scibot 21 Sep 2021
  
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  DOI: 10.1007/978-1-0716-1775-5_4
  
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link.springer.com/protocol/10.1007/978-1-0716-1775-5_4
Aug 2021
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Untitled document

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1. scibot 03 Aug 2021
  
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  DOI: 10.1016/j.cell.2017.11.018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5786493/
Feb 2021
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Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients

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1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.xcrm.2021.100202
  
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sciencedirect.com/science/article/pii/S2666379121000136
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Generation of two gene edited iPSC-lines carrying a DOX-inducible NGN2 expression cassette with and without GFP in the AAVS1 locus

1
1. scibot 12 Feb 2021
  
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  DOI: 10.1016/j.scr.2021.102240
  
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sciencedirect.com/science/article/pii/S1873506121000866
Sep 2020
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Human Placental MSC-Secreted IL-1β Enhances Neutrophil Bactericidal Functions during Hypervirulent Klebsiella Infection

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1. scibot 30 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.108188
  
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sciencedirect.com/science/article/pii/S2211124720311773
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Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107870
  
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sciencedirect.com/science/article/pii/S2211124720308512
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Loss of TET2 Affects Proliferation and Drug Sensitivity through Altered Dynamics of Cell-State Transitions

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.cels.2020.06.003
  
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sciencedirect.com/science/article/pii/S2405471220302003
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Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis

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1. scibot 08 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.03.031
  
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Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer

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  DOI: 10.1016/j.stem.2019.08.004
  
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A Unique Epigenomic Landscape Defines Human Erythropoiesis

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  DOI: 10.1016/j.celrep.2019.08.020
  
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Untitled document

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  DOI: 10.1016/j.stem.2018.12.002
  
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Untitled document

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  DOI: 10.1016/j.scr.2018.101368
  
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Untitled document

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  DOI: 10.1016/j.stem.2019.02.006
  
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Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence

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An In Vitro Model of Hematotoxicity: Differentiation of Bone Marrow–Derived Stem/Progenitor Cells into Hematopoietic Lineages and Evaluation of Lineage‐Specific Hematotoxicity

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Intrinsic Immunity Shapes Viral Resistance of Stem Cells

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