Hypothesis

46 Matching Annotations

Dec 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225025647-main-html.html

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.isci.2025.114303
  
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54.241.53.176/6616620d4f1dc598cdc85a941c81195110b67c2e/1-s2.0-S2589004225025647-main-html.html
Nov 2025
www.biorxiv.org www.biorxiv.org

Acute Myeloid Leukemia Relapse after Bromodomain Inhibitor Treatment or Chemotherapy is Characterized by Myc-Ras Transcriptional Remodeling

1
1. scibot 18 Nov 2025
  
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  DOI: 10.1101/2025.11.13.688312
  
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biorxiv.org/content/10.1101/2025.11.13.688312v1
Jul 2025
52.53.155.43 52.53.155.43

watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html

1
1. scibot 30 Jul 2025
  
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  AB_397798
  
  DOI: 10.1038/s44318-025-00506-0
  
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52.53.155.43/42423fb21c90eb6b2282f89153f3787d8f44c56d/watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html
Jun 2025
www.sciencedirect.com www.sciencedirect.com

RIPK4 promotes epidermal differentiation through phase separation and activation of LATS1/2

1
1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.devcel.2025.05.017
  
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sciencedirect.com/science/article/pii/S1534580725003284
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Focal Adhesion Kinase Orchestrates GLUT4 Translocation and Glucose Uptake via Cytoskeletal Turnover in Primary Adipocytes

1
1. scibot 24 May 2025
  
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  DOI: 10.1096/fj.202402764RR
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12093284/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration | Molecular Biology of the Cell

1
1. scibot 19 May 2025
  
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  AB_397798
  
  DOI: 10.1091/mbc.E24-11-0512
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11974963/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees

1
1. scibot 17 Dec 2024
  
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  DOI: 10.1016/j.cels.2018.01.008
  
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pmc.ncbi.nlm.nih.gov/articles/PMC5876136/
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration

1
1. scibot 05 Oct 2024
  
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  AB_397798
  
  DOI: 10.1101/2024.09.09.612106
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11419079/
Aug 2024
www.cell.com www.cell.com

Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114573
  
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cell.com/cell-reports/abstract/S2211-1247(24)00902-1
www.mdpi.com www.mdpi.com

Effects of Mild Excitotoxic Stimulus on Mitochondria Ca2+ Handling in Hippocampal Cultures of a Mouse Model of Alzheimer’s Disease

1
1. scibot 02 Aug 2024
  
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  610418
  
  DOI: 10.3390/cells10082046
  
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mdpi.com/2073-4409/10/8/2046/htm
May 2024
www.sciencedirect.com www.sciencedirect.com

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants

1
1. scibot 17 May 2024
  
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  DOI: 10.1016/j.molcel.2024.04.012
  
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sciencedirect.com/science/article/pii/S1097276524003277
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ubiquitin-specific protease 7 inhibitors reveal a differentiated mechanism of p53-driven anti-cancer activity

1
1. scibot 03 May 2024
  
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  DOI: 10.1016/j.isci.2024.109693
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11059122/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events

1
1. scibot 08 Feb 2024
  
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  RRID:AB_397798
  
  DOI: 10.1091/mbc.E23-03-0078
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10846623/
Jan 2024
www.molbiolcell.org www.molbiolcell.org

EHD2 regulates plasma membrane integrity and downstream insulin receptor signaling events

1
1. scibot 12 Jan 2024
  
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  RRID:AB_397798
  
  DOI: 10.1091/mbc.E23-03-0078
  
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molbiolcell.org/doi/10.1091/mbc.E23-03-0078
Sep 2023
www.sciencedirect.com www.sciencedirect.com

eIF3d controls the persistent integrated stress response

1
1. scibot 08 Sep 2023
  
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  DOI: 10.1016/j.molcel.2023.08.008
  
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sciencedirect.com/science/article/abs/pii/S1097276523006433
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

APOE expression and secretion are modulated by mitochondrial dysfunction

1
1. scibot 03 Jun 2023
  
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  AB_397798
  
  DOI: 10.7554/eLife.85779
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10231934/
Mar 2023
www.embopress.org www.embopress.org

Two Hippo signaling modules orchestrate liver size and tumorigenesis

2
1. scibot 16 Mar 2023
  
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  RRID:AB_397798
  
  DOI: 10.15252/embj.2022112126
  
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2. scibot 16 Mar 2023
  
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  RRID:AB_397798
  
  DOI: 10.15252/embj.2022112126
  
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embopress.org/doi/10.15252/embj.2022112126
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Mitochondrial RNA Granule Modulates Manganese-Dependent Cell Toxicity

1
1. scibot 17 Nov 2022
  
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  AB_397798
  
  DOI: 10.1091/mbc.E22-03-0096
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9635304/
Apr 2022
journals.biologists.com journals.biologists.com

Novel function of the C-Terminal region of the Hsp110 family member Osp94 in unfolded protein refolding

1
1. scibot 29 Apr 2022
  
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  DOI: 10.1242/jcs.258542
  
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journals.biologists.com/jcs/article/135/6/jcs258542/274905/Novel-function-of-the-C-terminal-region-of-the
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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

1
1. scibot 20 Apr 2022
  
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  RRID:AB_397798
  
  DOI: 10.1016/j.molcel.2022.03.027
  
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sciencedirect.com/science/article/pii/S1097276522002659
Mar 2022
www.sciencedirect.com www.sciencedirect.com

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones

1
1. scibot 23 Mar 2022
  
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  RRID:AB_397798
  
  DOI: 10.1016/j.celrep.2022.110541
  
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sciencedirect.com/science/article/pii/S2211124722002820
Oct 2021
www.embopress.org www.embopress.org

Promyelocytic leukemia protein targets MK2 to promote cytotoxicity

1
1. scibot 12 Oct 2021
  
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  RRID:AB_397798
  
  DOI: 10.15252/embr.202052254
  
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embopress.org/doi/full/10.15252/embr.202052254
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Oncogene-dependent sloppiness in mRNA translation

1
1. scibot 25 Sep 2021
  
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  RRID:AB_397798
  
  DOI: 10.1016/j.molcel.2021.09.002
  
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sciencedirect.com/science/article/pii/S109727652100736X
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis

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1. scibot 25 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109596
  
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sciencedirect.com/science/article/pii/S2211124721010342
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 10 Aug 2021
  
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  RRID:AB_397798
  
  DOI: 10.1016/j.cub.2018.11.066
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6345631/
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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

1
1. scibot 10 Aug 2021
  
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  DOI: 10.1016/j.cell.2018.11.024
  
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sciencedirect.com/science/article/pii/S0092867418315162
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Untitled document

1
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  DOI: 10.1016/j.cels.2018.01.008
  
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sciencedirect.com/science/article/pii/S2405471218300085
May 2021
www.sciencedirect.com www.sciencedirect.com

A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation

1
1. scibot 07 May 2021
  
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  DOI: 10.1016/j.immuni.2020.11.020
  
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sciencedirect.com/science/article/pii/S1074761320305070
Apr 2021
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Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma

1
1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.06.006
  
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  RRID:AB_397798 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S153561082030310X
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FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity

1
1. scibot 07 Apr 2021
  
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  RRID:AB_397798
  
  DOI: 10.1016/j.celrep.2021.108935
  
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sciencedirect.com/science/article/pii/S2211124721002497
Jan 2021
elifesciences.org elifesciences.org

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

1
1. scibot 05 Jan 2021
  
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  RRID:AB_397798
  
  DOI: 10.7554/eLife.63835
  
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elifesciences.org/articles/63835
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Axon-like protrusions promote small cell lung cancer migration and metastasis

1
1. scibot 12 Sep 2020
  
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  RRID:AB_397798
  
  DOI: 10.7554/eLife.50616
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6940020/
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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

1
1. scibot 06 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.03.062
  
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sciencedirect.com/science/article/pii/S0092867420303950
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Replication Study: A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

1
1. scibot 04 Sep 2020
  
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  RRID:AB_397798
  
  DOI: 10.7554/eLife.51019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7185998/
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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

1
1. scibot 04 Sep 2020
  
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Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

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Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

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Metabolic Remodeling during Liver Regeneration

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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

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