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68 Matching Annotations

Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Fibrillarin regulates epithelial integrity via EZH2-mediated modulation of scribble expression

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116608
  
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sciencedirect.com:5037/science/article/pii/S2211124725013804
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TOM1 G307D variant impairs interaction with TOLLIP, autophagosome-lysosome fusion and regulation of innate immunity

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1. scibot 16 Oct 2025
  
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  DOI: 10.1242/dmm.052140
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519566/
Jul 2025
www.biorxiv.org www.biorxiv.org

Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons

1
1. scibot 25 Jul 2025
  
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  DOI: 10.1101/2025.07.15.664857
  
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biorxiv.org/content/10.1101/2025.07.15.664857v1
www.cell.com www.cell.com

Signaling by intracellular β2-adrenergic receptors regulates AMPA receptor trafficking and synaptic plasticity

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116011
  
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cell.com/cell-reports/abstract/S2211-1247(25)00782-X
Jun 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Disruption of Retriever Function Impacts Retrograde Trafficking From Endosomes

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1. scibot 11 Jun 2025
  
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  DOI: 10.1002/cbin.70037
  
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onlinelibrary.wiley.com/doi/10.1002/cbin.70037
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ATG9A and ARFIP2 cooperate to control PI4P levels for lysosomal repair

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  DOI: 10.1016/j.devcel.2025.05.007
  
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sciencedirect.com/science/article/pii/S1534580725003181
Apr 2025
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CD36-mediated endocytosis of proteolysis-targeting chimeras

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1. scibot 19 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.036
  
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sciencedirect.com/science/article/pii/S0092867425003861
www.medrxiv.org www.medrxiv.org

Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission

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1. scibot 10 Apr 2025
  
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  DOI: 10.1101/2025.04.04.25325117
  
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medrxiv.org/content/10.1101/2025.04.04.25325117v1
52.53.155.43 52.53.155.43

Lysosome positioning affects NLRP3 inflammasome activation

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1. scibot 03 Apr 2025
  
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  DOI: 10.1101/2025.03.21.644552
  
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52.53.155.43/5e725b42faf6f4894ebfb1897ac6165b04d7cac3/PDF-html.html
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters in collective cell migration of epithelial cells

1
1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114986
  
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sciencedirect.com/science/article/pii/S2211124724013378
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Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.005
  
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sciencedirect.com/science/article/pii/S107476132400520X
Sep 2024
elifesciences.org elifesciences.org

S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

1
1. scibot 18 Sep 2024
  
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  DOI: 10.7554/eLife.94302
  
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elifesciences.org/articles/94302
Aug 2024
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C

1
1. scibot 02 Aug 2024
  
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  DOI: 10.1186/s12915-016-0332-8
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0332-8
Jun 2024
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EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.05.021
  
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sciencedirect.com/science/article/pii/S1534580724003393
May 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

EFA6A, an Exchange Factor for Arf6, Regulates NGF-Dependent TrkA Recycling From Early Endosomes and Neurite Outgrowth in PC12 Cells

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1. scibot 16 May 2024
  
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  DOI: 10.1111/tra.12936
  
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onlinelibrary.wiley.com/doi/10.1111/tra.12936
Apr 2024
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A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism

1
1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114119
  
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sciencedirect.com/science/article/pii/S2211124724004479
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

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1. scibot 07 Dec 2023
  
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  RRID:AB_397830
  
  DOI: 10.1016/j.celrep.2023.113529
  
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sciencedirect.com/science/article/pii/S2211124723015413
Nov 2023
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Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis

1
1. scibot 28 Nov 2023
  
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  RRID:AB_397830
  
  DOI: 10.1016/j.celrep.2023.113460
  
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sciencedirect.com/science/article/pii/S2211124723014729
Oct 2023
www.science.org www.science.org

Piezo1 activates noncanonical EGFR endocytosis and signaling

1
1. scibot 17 Oct 2023
  
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  DOI: 10.1126/sciadv.adi1328
  
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science.org/doi/10.1126/sciadv.adi1328
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Piezo1 activates noncanonical EGFR endocytosis and signaling

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1. scibot 05 Oct 2023
  
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  DOI: 10.1126/sciadv.adi1328
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10530101/
Jul 2023
52.53.155.43 52.53.155.43

Spatial topology of organelle is a new breast cancer cell classifier

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1. scibot 18 Jul 2023
  
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  DOI: 10.1016/j.isci.2023.107229
  
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52.53.155.43/0b73b858cb4a87cbda334afa43c7c6af2bc763d8/PIIS2589004223013068-html.html
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation

1
1. scibot 29 Jun 2023
  
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  DOI: 10.1016/j.neuron.2023.05.033
  
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sciencedirect.com/science/article/pii/S0896627323004348
dx.doi.org dx.doi.org

LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL

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1. scibot 08 Jun 2023
  
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  DOI: 10.1158/2159-8290.CD-22-0376
  
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dx.doi.org/10.1158/2159-8290.CD-22-0376
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein

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1. scibot 08 Apr 2023
  
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  DOI: 10.1083/jcb.202204042
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10071310/
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin

1
1. scibot 09 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106150
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
Feb 2023
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Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames

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1. scibot 23 Feb 2023
  
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  DOI: 10.1016/j.molcel.2023.01.023
  
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sciencedirect.com/science/article/pii/S1097276523000758
52.53.155.43 52.53.155.43

cd-22-0376-html.html

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  DOI: 10.1158/2159-8290.cd-22-0376
  
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52.53.155.43/a051cdc9b66cfe47aeb3f39770c1ce7cd380afb2/cd-22-0376-html.html
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MOSPD2 is an endoplasmic reticulum–lipid droplet tether functioning in LD homeostasis

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1. scibot 02 Dec 2022
  
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  DOI: 10.1083/jcb.202110044
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8996327/
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replication

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1. scibot 19 Nov 2022
  
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  DOI: 10.1080/15548627.2021.1999561
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9450962/
Sep 2022
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ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains

1
1. scibot 29 Sep 2022
  
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  DOI: 10.1016/j.devcel.2022.09.004
  
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sciencedirect.com/science/article/pii/S1534580722006347
Jul 2022
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Rapid macropinocytic transfer of α-synuclein to lysosomes

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111102
  
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sciencedirect.com/science/article/pii/S2211124722009044
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Compartmentalization of casein kinase 1 γ CSNK1G controls the intracellular trafficking of ceramide

1
1. scibot 08 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104624
  
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sciencedirect.com/science/article/pii/S2589004222008963
Jun 2022
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C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

1
1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104537
  
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sciencedirect.com/science/article/pii/S2589004222008082
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The non-adrenergic imidazoline-1 receptor protein Nischarin is a key regulator of astrocyte glutamate uptake

1
1. scibot 19 Apr 2022
  
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  DOI: 10.1016/j.isci.2022.104127
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9010640/
link.springer.com link.springer.com

Protrudin regulates FAK activation, endothelial cell migration and angiogenesis

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1. scibot 05 Apr 2022
  
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  RRID:AB_397830
  
  DOI: 10.1007/s00018-022-04251-z
  
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link.springer.com/article/10.1007/s00018-022-04251-z
Mar 2022
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Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense

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1. scibot 23 Mar 2022
  
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The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

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The endocytic pathway taken by cationic substances requires Rab14 but not Rab5 and Rab7

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Cytohesin-2 mediates group I metabotropic glutamate receptor-dependent mechanical allodynia through the activation of ADP ribosylation factor 6 in the spinal cord

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Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

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Microscopic image-based covariation network analysis for actin scaffold-modified insulin signaling

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UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

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ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

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The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

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BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

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PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

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G protein-regulated endocytic trafficking of adenylyl cyclase type 9

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Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

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BRAG2a mediates mGluR-dependent AMPA receptor internalization at excitatory postsynapses through the interaction with PSD-95 and endophilin 3

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TBC1D5-Catalyzed Cycling of Rab7 Is Required for Retromer-Mediated Human Papillomavirus Trafficking during Virus Entry

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Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform

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SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling

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LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

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The ER-Localized Transmembrane Protein TMEM39A/SUSR2 Regulates Autophagy by Controlling the Trafficking of the PtdIns(4)P Phosphatase SAC1

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VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX

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APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

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Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter

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A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

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Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

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A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity

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Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons

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The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C

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