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41 Matching Annotations

Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.112990
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12283747/
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ERRα and HIF-1α Cooperate to Enhance Breast Cancer Aggressiveness and Chemoresistance Under Hypoxic Conditions

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1. scibot 22 Jul 2025
  
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  DOI: 10.3390/cancers17142382
  
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mdpi.com/2072-6694/17/14/2382
Jan 2025
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Conserved patterns of transcriptional dysregulation, heterogeneity, and cell states in clear cell kidney cancer

1
1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115169
  
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sciencedirect.com/science/article/pii/S2211124724015201
Sep 2024
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MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ccell.2017.06.004
  
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sciencedirect.com/science/article/pii/S1535610817302544
Aug 2024
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Epitranscriptomic reader YTHDF2 regulates SEK1(MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress

1
1. scibot 23 Aug 2024
  
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sciencedirect.com/science/article/pii/S2589004224018443
Apr 2024
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HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation

1
1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114103
  
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sciencedirect.com/science/article/pii/S2211124724004315
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A pan-cancer analysis of the microbiome in metastatic cancer

1
1. scibot 10 Apr 2024
  
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  DOI: 10.1016/j.cell.2024.03.021
  
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sciencedirect.com/science/article/pii/S009286742400312X
Mar 2024
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Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes

2
1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113972
  
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2. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113972
  
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sciencedirect.com/science/article/pii/S2211124724003000
Feb 2024
52.53.155.43 52.53.155.43

The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

2
1. scibot 22 Feb 2024
  
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  DOI: 10.1152/ajpcell.00293.2023
  
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2. scibot 22 Feb 2024
  
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  DOI: 10.1152/ajpcell.00293.2023
  
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52.53.155.43/d532629e4f1cf755a6f5c302a21018f2c97350c4/reisbeck-et-al-2023-the-iron-chelator-and-oxphos-inhibitor-vlx600-induces-mitophagy-and-an-autophagy-dependent-type-of (1)-html.html
journals.physiology.org journals.physiology.org

The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

2
1. scibot 16 Feb 2024
  
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  DOI: 10.1152/ajpcell.00293.2023
  
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2. scibot 16 Feb 2024
  
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  RRID:AB_398272
  
  DOI: 10.1152/ajpcell.00293.2023
  
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journals.physiology.org/doi/10.1152/ajpcell.00293.2023
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Stromal-derived MAOB promotes prostate cancer growth and progression

1
1. scibot 14 Feb 2024
  
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  DOI: 10.1126/sciadv.adi4935
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
Dec 2023
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MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

1
1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.molcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1097276523009681
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitochondrial UQCC3 controls embryonic and tumor angiogenesis by regulating VEGF expression

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1. scibot 04 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107370
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393800/
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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

1
1. scibot 03 Aug 2023
  
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  RRID:AB_398272
  
  DOI: 10.1016/j.celrep.2023.112927
  
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sciencedirect.com/science/article/pii/S2211124723009385
Mar 2023
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Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions

1
1. scibot 28 Mar 2023
  
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  RRID:AB_398272
  
  DOI: 10.1016/j.jbc.2023.104650
  
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sciencedirect.com/science/article/pii/S0021925823002922
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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis

1
1. scibot 02 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112164
  
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sciencedirect.com/science/article/pii/S2211124723001754
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

1
1. scibot 13 Dec 2022
  
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  RRID:AB_398272
  
  DOI: 10.1186/s40170-022-00298-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9737747/
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Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells

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1. scibot 04 Dec 2022
  
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  DOI: 10.1016/j.cels.2022.11.003
  
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sciencedirect.com/science/article/pii/S2405471222004628
Nov 2022
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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

1
1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111652
  
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sciencedirect.com/science/article/pii/S2211124722015236
Sep 2022
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Target protein localization and its impact on PROTAC-mediated degradation

1
1. scibot 08 Sep 2022
  
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  DOI: 10.1016/j.chembiol.2022.08.004
  
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sciencedirect.com/science/article/pii/S2451945622003129
Jul 2022
www.researchsquare.com www.researchsquare.com

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1
1. scibot 13 Jul 2022
  
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  RRID:AB_398272
  
  DOI: 10.21203/rs.3.rs-658360/v1
  
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researchsquare.com/
Jun 2022
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Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia

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1. scibot 25 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104517
  
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sciencedirect.com/science/article/pii/S258900422200788X
Feb 2022
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Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions

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1. scibot 02 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110320
  
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sciencedirect.com/science/article/pii/S2211124722000316
Dec 2021
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Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling

1
1. scibot 29 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103607
  
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sciencedirect.com/science/article/pii/S2589004221015777
Oct 2021
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Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer

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1. scibot 21 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109852
  
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sciencedirect.com/science/article/pii/S221112472101319X
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HIF-1 recruits NANOG as a coactivator for TERT gene transcription in hypoxic breast cancer stem cells

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1. scibot 01 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109757
  
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sciencedirect.com/science/article/pii/S2211124721012110
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 11 Aug 2021
  
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  DOI: 10.1016/j.celrep.2018.09.057
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6205837/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

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  DOI: 10.1002/jcp.27359
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.27359
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Untitled document

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  DOI: 10.1002/jcp.26511
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6220985/
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma

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1. scibot 27 Oct 2020
  
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  DOI: 10.7554/eLife.58108
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer

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1. scibot 08 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108231
  
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pubmed.ncbi.nlm.nih.gov/33027658/
Sep 2020
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N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.molcel.2020.02.018
  
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sciencedirect.com/science/article/pii/S1097276520301118
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.chembiol.2020.06.013
  
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pubmed.ncbi.nlm.nih.gov/32668203/
www.cell.com www.cell.com

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

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1. scibot 04 Sep 2020
  
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  RRID: AB_398272
  
  DOI: 10.1016/j.celrep.2018.09.057
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31502-X
Jan 2020
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Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2018.11.093
  
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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.01.106
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719301433
Nov 2018
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1. scibot 05 Nov 2018
  
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Hypoxia negatively affects senescence in osteoclasts and delays osteoclastogenesis

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1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcp.26511