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PARP1 hyperactivation uncouples transcription from protein expression through nuclear RNA retention

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.molcel.2026.10.015
  
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sciencedirect.com/science/article/pii/S1097276526007203
Jul 2025
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watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html

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1. scibot 30 Jul 2025
  
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  DOI: 10.1038/s44318-025-00506-0
  
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52.53.155.43/42423fb21c90eb6b2282f89153f3787d8f44c56d/watanabe-et-al-als-associated-rna-binding-proteins-promote-unc13a-transcription-through-rest-downregulation-html.html
May 2025
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Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.039
  
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sciencedirect.com/science/article/pii/S0092867425005094
Jul 2024
rupress.org rupress.org

Identification of small molecule inhibitors of G3BP-driven stress granule formation

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1. scibot 30 Jul 2024
  
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  DOI: 10.1083/jcb.202308083
  
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rupress.org/jcb/article/223/3/e202308083/276529/Identification-of-small-molecule-inhibitors-of
Mar 2024
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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113965
  
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sciencedirect.com/science/article/pii/S2211124724002936
Nov 2023
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Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation

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1. scibot 03 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113358
  
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sciencedirect.com/science/article/pii/S2211124723013700
May 2022
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Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation

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1. scibot 26 May 2022
  
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  RRID:AB_398438
  
  DOI: 10.1016/j.isci.2022.104356
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9127583/
Jul 2021
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The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43

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1. scibot 14 Jul 2021
  
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  DOI: 10.1016/j.isci.2021.102733
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8259439/
May 2021
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Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.06.019
  
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sciencedirect.com/science/article/pii/S1097276520304214
Apr 2021
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Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.11.010
  
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sciencedirect.com/science/article/pii/S0092867420315270
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation

1
1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.080
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_398438
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ncbi.nlm.nih.gov/pmc/articles/PMC6996132/
Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_398438
  
  DOI: 10.1016/j.molcel.2018.12.006
  
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sciencedirect.com/science/article/pii/S1097276518310360
Nov 2017
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TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

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1. scibot 08 Nov 2017
  
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  Curator: @Jmenke
  
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  RRID:AB_398438 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627317306475