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The transcription factor Eomes drives a stemness program in CD4+ T cells that promotes anti-tumor immunity in response to immunotherapy

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1. scibot 26 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.05.018
  
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sciencedirect.com/science/article/pii/S1074761326002293
Jun 2026
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Trans-presentation of IL-6Rα by macrophages drives colorectal cancer development

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1. scibot 23 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117549
  
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sciencedirect.com/science/article/pii/S2211124726006273
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Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

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1. scibot 18 Jun 2026
  
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  DOI: 10.1126/sciadv.aee0517
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13262630/
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Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis

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  DOI: 10.1126/sciadv.aee0517
  
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science.org/doi/10.1126/sciadv.aee0517
May 2026
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Newly isolated human-derived Lactobacillus fermentum strain stimulates IFN-γ-secreting CD8+ T cells for enhanced anti-cancer immunity

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115642
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13125905/
Mar 2026
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A senescent tumor cell-derived nanovesicle directly primes splenic T cells to potentiate cancer radiotherapy

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102709
  
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sciencedirect.com/science/article/pii/S2666379126001266
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Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.03.005
  
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Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.03.004
  
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sciencedirect.com/science/article/pii/S153561082600156X
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Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.cmet.2026.02.016
  
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sciencedirect.com/science/article/pii/S1550413126000859
Sep 2025
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1-s2.0-S2589004225017985-main-html.html

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113537
  
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52.53.155.43/bfa103a56e03ca8260532bade686a824030c14b2/1-s2.0-S2589004225017985-main-html.html
Aug 2025
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2025.08.13.669552v1.full-html.html

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1. scibot 22 Aug 2025
  
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  DOI: 10.1101/2025.08.13.669552
  
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52.53.155.43/cbef6d49734833e21d46745b8a2764b4c745ed76/2025.08.13.669552v1.full-html.html
Mar 2025
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Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.chom.2025.03.004
  
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sciencedirect.com/science/article/pii/S1931312825000873
Feb 2025
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Rev-erb-α antagonism in alveolar macrophages protects against pneumococcal infection in elderly mice

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1. scibot 06 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115273
  
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sciencedirect.com/science/article/pii/S2211124725000440
Nov 2024
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Local adaptive immunity in atherosclerosis with T cell activation by aortic DCs accelerates pathogenesis

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1. scibot 08 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111144
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11536043/
Sep 2024
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PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination

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1. scibot 05 Sep 2024
  
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  DOI: 10.1158/2326-6066.CIR-23-0289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11369622/
May 2024
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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

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1. scibot 31 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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2. scibot 31 May 2024
  
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  DOI: 10.1016/j.immuni.2024.05.006
  
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sciencedirect.com/science/article/pii/S1074761324002590
Mar 2024
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A tetravalent nanovaccine that inhibits growth of HPV-associated head and neck carcinoma via dendritic and T cell activation

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1. scibot 27 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109439
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10957412/
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IKK2 controls the inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model

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1. scibot 26 Mar 2024
  
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  DOI: 10.1038/s41467-024-45870-3
  
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nature.com/articles/s41467-024-45870-3
Feb 2024
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LAG-3- and CXCR5-expressing CD4 T cells display progenitor-like properties during chronic visceral leishmaniasis

2
1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113879
  
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  DOI: 10.1016/j.celrep.2024.113879
  
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sciencedirect.com/science/article/pii/S2211124724002079
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Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113797
  
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Inhibition of choline metabolism in an angioimmunoblastic T-cell lymphoma preclinical model reveals a new metabolic vulnerability as possible target for treatment

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1. scibot 08 Feb 2024
  
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  DOI: 10.1186/s13046-024-02952-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10845598/
Dec 2023
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FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.xcrm.2023.101256
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10772324/
Nov 2023
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Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

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1. scibot 02 Nov 2023
  
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  DOI: 10.7150/thno.85106
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10614673/
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Lung cDC1 and cDC2 dendritic cells priming naive CD8+ T cells in situ prior to migration to draining lymph nodes

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1. scibot 02 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113299
  
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sciencedirect.com/science/article/pii/S2211124723013116
Aug 2023
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Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.neuron.2023.07.015
  
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sciencedirect.com/science/article/pii/S0896627323005482
Jun 2023
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xCT-mediated glutamate excretion in white adipocytes stimulates interferon-γ production by natural killer cells in obesity

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112636
  
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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  DOI: 10.1016/j.celrep.2023.112599
  
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Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

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  DOI: 10.1016/j.immuni.2023.05.004
  
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sciencedirect.com/science/article/pii/S1074761323002212
May 2023
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The eIF4EBP-eIF4E axis regulates CD4+ T cell differentiation through modulation of T cell activation and metabolism

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1. scibot 16 May 2023
  
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  DOI: 10.1016/j.isci.2023.106683
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10176268/
Mar 2023
europepmc.org europepmc.org

Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma

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1. scibot 25 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.03.004
  
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europepmc.org/article/med/36963400
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Pre-existing immunity modulates responses to mRNA boosters

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  DOI: 10.1016/j.celrep.2023.112167
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9928730/
Jan 2023
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Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111897
  
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sciencedirect.com/science/article/pii/S221112472201796X
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Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.celrep.2023.111991
  
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GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

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1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.12.009
  
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Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation

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A lentiviral vector encoding fusion of light invariant chain and mycobacterial antigens induces protective CD4+ T cell immunity

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Mycobacterium tuberculosis infection drives a type I IFN signature in lung lymphocytes

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Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus

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Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation

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Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy

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The role of protease-activated receptor 1 signaling in CD8 T cell effector functions

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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

1
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

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NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes

1
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Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models

1
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  DOI: 10.1016/j.chom.2020.12.010
  
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Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance

1
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Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells

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  DOI: 10.1016/j.celrep.2020.108219
  
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Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir

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Roles of endogenous IL-10 and IL-10-competent CD1d hi and CD5 + B cells in autoimmune thyroiditis in NOD.H-2 h4 mice

1
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  DOI: 10.1210/endocr/bqaa033
  
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Jan 2020
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Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection

1
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The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development

1
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Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons

1
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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation

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Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens

1
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Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers

1
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Untitled document

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Nov 2018
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LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

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Nov 2017
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Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells

1
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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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Inflammatory Ly6Chigh Monocytes Protect against Candidiasis through IL-15-Driven NK Cell/Neutrophil Activation

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Conditional Ablation of Astroglial CCL2 Suppresses CNS Accumulation of M1 Macrophages and Preserves Axons in Mice with MOG Peptide EAE

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