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56 Matching Annotations

Oct 2025
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Protocol for generating liver organoids containing Kupffer cells using human iPSCs

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.xpro.2025.104138
  
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sciencedirect.com/science/article/pii/S2666166725005441
Sep 2025
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FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

1
1. scibot 23 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102365
  
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Lentiviral vectors for hematopoietic stem cell gene therapy restore α-globin expression in α-thalassemia red blood cells

1
1. scibot 18 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102362
  
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sciencedirect.com/science/article/pii/S2666379125004355
May 2025
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Regulatable C-X-C chemokine receptor type 4 in iPSC-derived NK cells improves bone marrow chemotaxis and targeting resident tumor

1
1. scibot 19 May 2025
  
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  DOI: 10.1016/j.tibtech.2025.02.018
  
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sciencedirect.com/science/article/pii/S0167779925000812
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genetic Screen in a Pre-Clinical Model of Sarcoma Development Defines Drivers and Therapeutic Vulnerabilities

1
1. scibot 16 May 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-1238
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11530313/
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Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis

1
1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115671
  
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sciencedirect.com/science/article/pii/S2211124725004425
Feb 2025
aacrjournals.org aacrjournals.org

Impact of scFv on functionality and safety of third generation CD123 CAR T cells

1
1. scibot 14 Feb 2025
  
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  DOI: 10.1158/2326-6066.CIR-23-0548
  
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aacrjournals.org/cancerimmunolres/article/12/8/1090/746566/Impact-of-scFv-on-Functionality-and-Safety-of
Jan 2025
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CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells

1
1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2024.101889
  
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sciencedirect.com/science/article/pii/S2666379124006608
Apr 2024
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Identification of cells of leukemic stem cell origin with non-canonical regenerative properties

1
1. scibot 09 Apr 2024
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.xcrm.2024.101485
  
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sciencedirect.com/science/article/pii/S2666379124001319
Mar 2024
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Integration of Kupffer cells into human iPSC-derived liver organoids for modeling liver dysfunction in sepsis

1
1. scibot 14 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113918
  
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sciencedirect.com/science/article/pii/S2211124724002468
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Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing

1
1. scibot 06 Mar 2024
  
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  DOI: 10.1038/s41467-024-46114-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10908830/
Feb 2024
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α1,3-fucosylation treatment improves cord blood CD34 negative hematopoietic stem cell navigation

1
1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108882
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10845921/
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Immune Surveillance of Acute Myeloid Leukemia Is Mediated by HLA-Presented Antigens on Leukemia Progenitor Cells

1
1. scibot 01 Feb 2024
  
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  RRID:AB_398614
  
  DOI: 10.1158/2643-3230.BCD-23-0020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10618727/
Aug 2023
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Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis

1
1. scibot 27 Aug 2023
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.cell.2023.07.037
  
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sciencedirect.com/science/article/pii/S0092867423008528
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Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells

2
1. scibot 24 Aug 2023
  
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  RRID:AB_398614
  
  DOI: 10.1038/s41467-023-40222-z
  
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2. scibot 24 Aug 2023
  
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  RRID:AB_398614
  
  DOI: 10.1038/s41467-023-40222-z
  
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nature.com/articles/s41467-023-40222-z
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Human Multi-Chimeric Cell (HMCC) Therapy as a Novel Approach for Tolerance Induction in Transplantation

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1. scibot 23 Aug 2023
  
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  DOI: 10.1007/s12015-023-10608-z
  
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link.springer.com/article/10.1007/s12015-023-10608-z
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Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia

1
1. scibot 04 Aug 2023
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.xcrm.2023.101108
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10394166/
Jul 2023
www.embopress.org www.embopress.org

Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells

1
1. scibot 29 Jul 2023
  
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  RRID:AB_398614
  
  DOI: 10.15252/embr.202256279
  
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embopress.org/doi/10.15252/embr.202256279
Mar 2023
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A bispecific T cell engager recruits both type 1 NKT and Vγ9Vδ2-T cells for the treatment of CD1d-expressing hematological malignancies

1
1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.xcrm.2023.100961
  
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sciencedirect.com/science/article/pii/S2666379123000538
Jan 2023
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Fluorescence-activated cell sorting and phenotypic characterization of human fibro-adipogenic progenitors

1
1. scibot 19 Jan 2023
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.xpro.2022.102008
  
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sciencedirect.com/science/article/pii/S2666166722008887
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Endometriosis-associated mesenchymal stem cells support ovarian clear cell carcinoma through iron regulation

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1. scibot 06 Jan 2023
  
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  RRID:AB_398614
  
  DOI: 10.1158/0008-5472.CAN-22-1294
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9755968/
Dec 2022
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Chemically defined generation of human definitive hematopoietic stem and progenitor cells

1
1. scibot 18 Dec 2022
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.xpro.2022.101953
  
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sciencedirect.com/science/article/pii/S2666166722008334
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Temporal molecular program of human hematopoietic stem and progenitor cells after birth

1
1. scibot 11 Dec 2022
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.devcel.2022.11.013
  
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sciencedirect.com/science/article/pii/S1534580722008139
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hematopoietic Stem Cell Heterogeneity Is Linked to the Initiation and Therapeutic Response of Myeloproliferative Neoplasms

1
1. scibot 22 Aug 2022
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.stem.2021.02.026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7613297/
Oct 2021
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Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

1
1. scibot 22 Oct 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.cmet.2021.10.001
  
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sciencedirect.com/science/article/pii/S1550413121004794
Sep 2021
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CombiFlow: Flow cytometry-based identification and characterization of genetically and functionally distinct AML subclones

1
1. scibot 28 Sep 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.xpro.2021.100864
  
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sciencedirect.com/science/article/pii/S2666166721005700
Aug 2021
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RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia

1
1. scibot 18 Aug 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.celrep.2021.109559
  
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sciencedirect.com/science/article/pii/S2211124721009931
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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

1
1. scibot 16 Aug 2021
  
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  DOI: 10.1016/j.stem.2021.07.009
  
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sciencedirect.com/science/article/pii/S1934590921002940
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Dysregulated hematopoiesis in bone marrow marks severe COVID-19

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1. scibot 15 Aug 2021
  
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  DOI: 10.1038/s41421-021-00296-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8335717/
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Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells

1
1. scibot 12 Aug 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.celrep.2019.02.021
  
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sciencedirect.com/science/article/pii/S2211124719301834
Jul 2021
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NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia

1
1. scibot 30 Jul 2021
  
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  APC Mouse Anti-Human CD34 antibody
  
  DOI: 10.1016/j.stem.2019.08.016
  
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sciencedirect.com/science/article/pii/S1934590919303510
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Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells

1
1. scibot 28 Jul 2021
  
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  RRID: AB_398614
  
  DOI: 10.1016/j.celrep.2019.02.021
  
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sciencedirect.com/science/article/pii/S2211124719301834
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Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis

1
1. scibot 27 Jul 2021
  
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  RRID: 4338604
  
  DOI: 10.1016/j.stem.2018.04.012
  
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sciencedirect.com/science/article/pii/S1934590918301747
May 2021
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Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics

1
1. scibot 12 May 2021
  
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  DOI: 10.1016/j.chembiol.2021.04.014
  
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sciencedirect.com/science/article/pii/S2451945621002075
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UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

1
1. scibot 09 May 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.stem.2020.12.002
  
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Mar 2021
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Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells

1
1. scibot 28 Mar 2021
  
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  RRID:AB_398614
  
  DOI: 10.1158/2643-3230.BCD-20-0161
  
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Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients

1
1. scibot 17 Mar 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.celrep.2021.108845
  
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Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions

1
1. scibot 10 Mar 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.celrep.2021.108818
  
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Feb 2021
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Hematopoietic Stem Cell Heterogeneity Is Linked to the Initiation and Therapeutic Response of Myeloproliferative Neoplasms

1
1. scibot 25 Feb 2021
  
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  DOI: 10.1016/j.stem.2021.01.018
  
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TALEN-mediated biallelic inactivation of MYB in human embryonic stem cell lines WAe001-A-45 and WAe001-A-46

1
1. scibot 24 Feb 2021
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.scr.2020.101854
  
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Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1016/j.xcrm.2021.100202
  
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An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism

1
1. scibot 04 Feb 2021
  
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  DOI: 10.1016/j.celrep.2021.108723
  
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Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis

1
1. scibot 15 Dec 2020
  
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  CD34
  
  DOI: 10.1016/j.celrep.2020.108473
  
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Sep 2020
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Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy

1
1. scibot 25 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.09.001
  
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LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation

1
1. scibot 12 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107600
  
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Generation of RUNX1-null reporter human embryonic stem cell line GIBHe008-A

1
1. scibot 11 Sep 2020
  
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  AB_398614
  
  DOI: 10.1016/j.scr.2020.101800
  
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Clonal Origin in Normal Adults of All Blood Lineages and Circulating Hematopoietic Stem Cells

1
1. scibot 04 Sep 2020
  
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  APC Mouse Anti-Human CD34
  
  DOI: 10.1016/j.exphem.2020.01.005
  
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Jan 2020
elifesciences.org elifesciences.org

Human perivascular stem cell-derived extracellular vesicles mediate bone repair

1
1. scibot 13 Jan 2020
  
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  RRID:AB_398614
  
  DOI: 10.7554/eLife.48191
  
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Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.celrep.2019.06.084
  
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Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

1
1. scibot 13 Jan 2020
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.ccell.2019.06.003
  
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_398614
  
  DOI: 10.1016/j.stem.2018.12.003
  
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sciencedirect.com/science/article/pii/S1934590918305939
Nov 2018
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Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1535610818303672
Nov 2017
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Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1

1
1. scibot 08 Nov 2017
  
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Hoxa9 and EGFP reporter expression in human Embryonic Stem Cells (hESC) as useful tools for studying human development

1
1. scibot 08 Nov 2017
  
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Sam68 Allows Selective Targeting of Human Cancer Stem Cells

1
1. scibot 08 Nov 2017
  
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  AB_398614
  
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