48 Matching Annotations
  1. Last 7 days
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    Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia
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    science.org/doi/10.1126/sciadv.adx8662
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12525776/
  4. Jun 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males
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    pmc.ncbi.nlm.nih.gov/articles/PMC12147913/
  6. May 2025
  7. www.sciencedirect.com www.sciencedirect.com
    De novo serine biosynthesis is protective in mitochondrial disease
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    sciencedirect.com/science/article/pii/S2211124725004814
  8. Apr 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980836/
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    ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution
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    science.org/doi/10.1126/sciadv.adu5091
  11. Nov 2024
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    Opposing roles for AMPK in regulating distinct mitophagy pathways
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    sciencedirect.com/science/article/pii/S1097276524008657
  13. Aug 2024
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    OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
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    sciencedirect.com/science/article/pii/S109727652400618X
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    CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10818064/
  16. Jul 2024
  17. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017851-main-html.html
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    52.53.155.43/28f1f0cd51770599356cfb72d036c0e468b38b34/1-s2.0-S2589004224017851-main-html.html
  18. May 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089353/
  20. Feb 2024
  21. link.springer.com link.springer.com
    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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    link.springer.com/article/10.1186/s12915-021-00979-5
  22. Apr 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
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    sciencedirect.com/science/article/pii/S221112472300445X
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    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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    sciencedirect.com/science/article/pii/S1550413123001304
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    Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission
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    sciencedirect.com/science/article/pii/S0753332223004043
  26. Dec 2022
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10265649/
  28. Aug 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids
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    sciencedirect.com/science/article/pii/S2211124722010154
  30. Jun 2022
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
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    ncbi.nlm.nih.gov/pmc/articles/PMC9183236/
  32. May 2022
  33. www.sciencedirect.com www.sciencedirect.com
    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
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    sciencedirect.com/science/article/pii/S1534580722003069
  34. Mar 2022
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    Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria
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    sciencedirect.com/science/article/pii/S0960982222003281
  36. Dec 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence
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    ncbi.nlm.nih.gov/pmc/articles/PMC8637926/
  38. Oct 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Adaptive translational pausing is a hallmark of the cellular response to severe environmental stress
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    sciencedirect.com/science/article/pii/S109727652100798X
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
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    ncbi.nlm.nih.gov/pmc/articles/PMC8478418/
  41. Aug 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation
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    sciencedirect.com/science/article/pii/S2211124721009992
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study
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    ncbi.nlm.nih.gov/pmc/articles/PMC6234033/
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    Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis
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    sciencedirect.com/science/article/pii/S1550413121003247
  45. Jul 2021
  46. link.springer.com link.springer.com
    <Emphasis Type="Italic">MSTO1</Emphasis> mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement
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    link.springer.com/article/10.1007/s00401-019-02059-z
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study
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    ncbi.nlm.nih.gov/pmc/articles/PMC6234033/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6283434/
  49. May 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21
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    ncbi.nlm.nih.gov/pmc/articles/PMC8128440/
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    Mitochondrial SIRT3 confers neuroprotection in Huntington’s disease by regulation of oxidative challenges and mitochondrial dynamics
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    sciencedirect.com/science/article/pii/S0891584920316440
  52. Mar 2021
  53. link.springer.com link.springer.com
    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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    link.springer.com/article/10.1186/s12915-021-00979-5
  54. www.sciencedirect.com www.sciencedirect.com
    The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism
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    sciencedirect.com/science/article/pii/S2211124721001832
  55. Dec 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
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    sciencedirect.com/science/article/pii/S1550413120305982
  57. Sep 2020
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitophagy, Autophagy and Cell Death: The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC6766616/
  59. Aug 2020
  60. academic.oup.com academic.oup.com
    Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
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    academic.oup.com/hmg/article/29/9/1547/5825277
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions
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    sciencedirect.com/science/article/pii/S1550413119304486
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Subcellular NAMPT‐mediated NAD+ salvage pathways and their roles in bioenergetics and neuronal protection after ischemic injury
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14878
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice
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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24397
  65. Nov 2018
  66. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy
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    sciencedirect.com/science/article/pii/S1550413118305035
  67. www.sciencedirect.com www.sciencedirect.com
    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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    sciencedirect.com/science/article/pii/S1550413118303930
  68. www.sciencedirect.com www.sciencedirect.com
    Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism
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    sciencedirect.com/science/article/pii/S2451945617304282
  69. www.jneurosci.org www.jneurosci.org
    Lack of Parkin Anticipates the Phenotype and Affects Mitochondrial Morphology and mtDNA Levels in a Mouse Model of Parkinson's Disease
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    jneurosci.org/content/38/4/1042
  70. academic.oup.com academic.oup.com
    Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity
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    academic.oup.com/endo/article/159/1/323/4411795
  71. Nov 2017
  72. www.sciencedirect.com www.sciencedirect.com
    Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
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    sciencedirect.com/science/article/pii/S009286741631652X
  73. www.sciencedirect.com www.sciencedirect.com
    Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex
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    sciencedirect.com/science/article/pii/S1097276517304410
  74. www.sciencedirect.com www.sciencedirect.com
    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
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    sciencedirect.com/science/article/pii/S1097276517304409
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC5016092/