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Oct 2025
www.biorxiv.org www.biorxiv.org

Dishevelled drives Wnt-stimulated disassembly of primary cilia through a unique PDZ-mediated binding mode with Daple and Girdin

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  DOI: 10.1101/2025.09.26.678488
  
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biorxiv.org/content/10.1101/2025.09.26.678488v1
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation

1
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  DOI: 10.1038/s41467-025-63976-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12462528/
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Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration

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  DOI: 10.1016/j.cell.2025.08.031
  
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sciencedirect.com/science/article/pii/S0092867425010207
elifesciences.org elifesciences.org

Membrane binding properties of the cytoskeletal protein bactofilin

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1. scibot 04 Sep 2025
  
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  DOI: 10.7554/eLife.100749.2
  
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elifesciences.org/reviewed-preprints/100749
52.53.155.43 52.53.155.43

1-s2.0-S2589004225017559-main-html.html

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52.53.155.43/041d2f7022333b742915f1c03c0e21785d958c95/1-s2.0-S2589004225017559-main-html.html
Aug 2025
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BIN1 expression in the presynaptic compartment leads to isoform-specific synaptotoxicity

1
1. scibot 19 Aug 2025
  
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  DOI: 10.1101/2025.08.11.669624
  
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biorxiv.org/content/10.1101/2025.08.11.669624v1
Jun 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

A GLP-1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl-evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats

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1. scibot 13 Jun 2025
  
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  DOI: 10.1111/bph.70096
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70096
May 2025
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Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor

1
1. scibot 28 May 2025
  
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  DOI: 10.1038/s41467-025-59984-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12095580/
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TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115616
  
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sciencedirect.com/science/article/pii/S2211124725003870
Mar 2025
www.biorxiv.org www.biorxiv.org

Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation

1
1. scibot 20 Mar 2025
  
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  DOI: 10.1101/2025.03.14.642875
  
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biorxiv.org/content/10.1101/2025.03.14.642875v1
Dec 2024
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Design principles to tailor Hsp104 therapeutics

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  DOI: 10.1016/j.celrep.2024.115005
  
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sciencedirect.com/science/article/pii/S2211124724013561
Sep 2024
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Osmotic stress induces formation of both liquid condensates and amyloids by a yeast prion domain

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.jbc.2024.107766
  
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sciencedirect.com/science/article/pii/S0021925824022671
Aug 2024
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RNA interacts with topoisomerase I to adjust DNA topology

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.07.032
  
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sciencedirect.com/science/article/pii/S1097276524006300
Jun 2024
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Activity- and sleep-dependent regulation of tonic inhibition by Shisa7

2
1. scibot 26 Jun 2024
  
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  DOI: 10.1016/j.celrep.2021.108899
  
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2. scibot 26 Jun 2024
  
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  DOI: 10.1016/j.celrep.2021.108899
  
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sciencedirect.com/science/article/pii/S2211124721002138
May 2024
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Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies

1
1. scibot 21 May 2024
  
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  DOI: 10.1016/j.neuron.2024.05.003
  
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sciencedirect.com/science/article/pii/S0896627324003283
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The virulence regulator VirB from Shigella flexneri uses a CTP-dependent switch mechanism to activate gene expression

1
1. scibot 10 Jan 2024
  
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  DOI: 10.1038/s41467-023-44509-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10770331/
Nov 2023
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Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication

1
1. scibot 27 Nov 2023
  
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  DOI: 10.1016/j.molcel.2021.03.003
  
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sciencedirect.com/science/article/pii/S1097276521001714
Oct 2023
www.cell.com www.cell.com

ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct

1
1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113099
  
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cell.com/cell-reports/abstract/S2211-1247(23)01110-5
Aug 2023
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Tuning Hsp104 specificity to selectively detoxify α-synuclein

1
1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.molcel.2023.07.029
  
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sciencedirect.com/science/article/abs/pii/S1097276523006044
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DipM controls multiple autolysins and mediates a regulatory feedback loop promoting cell constriction in Caulobacter crescentus

1
1. scibot 14 Jul 2023
  
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  DOI: 10.1038/s41467-023-39783-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10336132/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A dynamic bactofilin cytoskeleton recruits an M23 endopeptidase to control bacterial morphogenesis

1
1. scibot 18 May 2023
  
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  DOI: 10.7554/eLife.86577
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10945521/
Mar 2023
www.biorxiv.org www.biorxiv.org

A dynamic bactofilin cytoskeleton recruits an M23 endopeptidase to control bacterial morphogenesis

1
1. scibot 31 Mar 2023
  
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  DOI: 10.1101/2023.02.27.530196
  
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biorxiv.org/content/10.1101/2023.02.27.530196v2
Feb 2023
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Physcomitrium patens PpRIC, an ancestral CRIB-domain ROP effector, inhibits auxin-induced differentiation of apical initial cells

1
1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112130
  
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sciencedirect.com/science/article/pii/S2211124723001419
Jan 2023
www.pnas.org www.pnas.org

MipZ caps the plus-end of FtsZ polymers to promote their rapid disassembly

1
1. scibot 12 Jan 2023
  
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  DOI: 10.1073/pnas.2208227119
  
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pnas.org/doi/abs/10.1073/pnas.2208227119
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DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling

1
1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111986
  
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sciencedirect.com/science/article/pii/S2211124722018903
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Zinc-finger protein Zpr1 is a bespoke chaperone essential for eEF1A biogenesis

1
1. scibot 12 Jan 2023
  
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  DOI: 10.1016/j.molcel.2022.12.012
  
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sciencedirect.com/science/article/pii/S1097276522011698
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MDM2 Aggravates Adipose Tissue Dysfunction through Ubiquitin-mediated STEAP4 Degradation

1
1. scibot 24 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104544
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9209722/
Apr 2022
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Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

1
1. scibot 14 Apr 2022
  
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  DOI: 10.1016/j.ydbio.2022.04.004
  
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sciencedirect.com/science/article/pii/S0012160622000653
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects

1
1. scibot 11 Jan 2022
  
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  DOI: 10.1186/s40478-021-01285-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8742943/
Dec 2021
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Remodeling-defective GPI-anchored proteins on the plasma membrane activate the spindle assembly checkpoint

1
1. scibot 29 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110120
  
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sciencedirect.com/science/article/pii/S2211124721016144
Aug 2021
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Untitled document

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  DOI: 10.1016/j.str.2018.11.001
  
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sciencedirect.com/science/article/pii/S0969212618304209
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 01 Aug 2021
  
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  DOI: 10.1111/bph.15495
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15495
Jul 2021
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Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy

1
1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.celrep.2019.11.058
  
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sciencedirect.com/science/article/pii/S2211124719315499
www.frontiersin.org www.frontiersin.org

Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization

1
1. scibot 30 Jul 2021
  
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  anti-GFP
  
  DOI: 10.3389/fncel.2019.00330
  
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frontiersin.org/articles/10.3389/fncel.2019.00330/full
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Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D2 Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor

1
1. scibot 29 Jul 2021
  
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  rabbit anti-GFP
  
  DOI: 10.3390/biom9080368
  
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mdpi.com/2218-273X/9/8/368/htm
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Scribble Scaffolds a Signalosome for Active Forgetting

1
1. scibot 27 Jul 2021
  
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  AB_439690
  
  DOI: 10.1016/j.neuron.2016.05.010
  
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sciencedirect.com/science/article/pii/S0896627316301702
May 2021
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

1
1. scibot 26 May 2021
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.celrep.2021.109184
  
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sciencedirect.com/science/article/pii/S2211124721005295
Apr 2021
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Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling

1
1. scibot 27 Apr 2021
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.cels.2021.02.001
  
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sciencedirect.com/science/article/pii/S2405471221000405
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DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation

1
1. scibot 16 Apr 2021
  
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  GFP
  
  DOI: 10.1016/j.bbamcr.2021.118994
  
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sciencedirect.com/science/article/pii/S0167488921000483
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Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication

1
1. scibot 02 Apr 2021
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.molcel.2021.03.003
  
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sciencedirect.com/science/article/pii/S1097276521001714
Mar 2021
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Activity- and sleep-dependent regulation of tonic inhibition by Shisa7

1
1. scibot 24 Mar 2021
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.celrep.2021.108899
  
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sciencedirect.com/science/article/pii/S2211124721002138
Feb 2021
www.cell.com www.cell.com

A Global Map of G Protein Signaling Regulation by RGS Proteins

1
1. scibot 24 Feb 2021
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.cell.2020.08.052
  
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cell.com/cell/fulltext/S0092-8674(20)31140-5
Jan 2021
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Therapeutic genetic variation revealed in diverse Hsp104 homologs

1
1. scibot 08 Jan 2021
  
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  RRID:AB_439690
  
  DOI: 10.7554/eLife.57457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7785292/
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A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA

1
1. scibot 08 Jan 2021
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.celrep.2020.108586
  
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sciencedirect.com/science/article/pii/S2211124720315758
Oct 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation

1
1. scibot 07 Oct 2020
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.celrep.2020.108235
  
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pubmed.ncbi.nlm.nih.gov/33027661/
Sep 2020
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Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex

1
1. scibot 11 Sep 2020
  
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  RRID:AB_439690
  
  DOI: 10.7554/eLife.53789
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7289601/
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DIX Domain Polymerization Drives Assembly of Plant Cell Polarity Complexes

1
1. scibot 07 Sep 2020
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.cell.2020.01.011
  
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sciencedirect.com/science/article/pii/S0092867420300581
Jan 2020
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Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.celrep.2019.07.069
  
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sciencedirect.com/science/article/pii/S2211124719309738
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ParB-type DNA Segregation Proteins Are CTP-Dependent Molecular Switches

1
1. scibot 13 Jan 2020
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.cell.2019.11.015
  
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sciencedirect.com/science/article/pii/S0092867419312711
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Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein

1
1. scibot 13 Jan 2020
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.neuron.2019.09.001
  
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sciencedirect.com/science/article/pii/S0896627319307743
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_439690
  
  DOI: 10.1016/j.neuron.2019.01.002
  
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sciencedirect.com/science/article/pii/S0896627319300030
Nov 2018
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Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0896627318306834
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An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0896627317311248
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5721578/
wellcomeopenresearch.org wellcomeopenresearch.org

Perturbation of PALB2 function by the T413S mutation found in small cell lung cancer

1
1. scibot 05 Nov 2018
  
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  Curator: @patriciaelyse_
  
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wellcomeopenresearch.org/articles/2-110
Nov 2017
www.jneurosci.org www.jneurosci.org

Mutant huntingtin is secreted via a late endosomal/lysosomal unconventional secretory pathway

1
1. scibot 08 Nov 2017
  
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jneurosci.org/content/37/37/9000
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Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

1
1. scibot 08 Nov 2017
  
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  AB_439690
  
  Curator: @chewbeccax
  
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sciencedirect.com/science/article/pii/S1097276517304367
elifesciences.org elifesciences.org

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9

1
1. scibot 08 Nov 2017
  
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  AB_439690
  
  Curator: @chewbeccax
  
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elifesciences.org/content/6/e20882