109 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor
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    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.cell.2024.09.005

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    sciencedirect.com/science/article/pii/S0092867424010237
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Revealing a hidden conducting state by manipulating the intracellular domains in KV10.1 exposes the coupling between two gating mechanisms
    1
    1. scibot 18 Sep 2024
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      DOI: 10.7554/eLife.91420

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    ncbi.nlm.nih.gov/pmc/articles/PMC11390113/
  4. Aug 2024
  5. www.sciencedirect.com www.sciencedirect.com
    BDNF-dependent nano-organization of Neogenin and the WAVE Regulatory Complex promotes actin remodelling in dendritic spines
    1
    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S2589004224018467
  6. www.cell.com www.cell.com
    Genome-scale exon perturbation screens uncover exons critical for cell fitness
    1
    1. scibot 13 Aug 2024
      RRID:AB_439694

      DOI: 10.1016/j.molcel.2024.05.024

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    cell.com/molecular-cell/abstract/S1097-2765(24)00447-7
  7. Jul 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Msc1 is a nuclear envelope protein that reinforces DNA repair in late mitosis
    1
    1. scibot 20 Jul 2024
      RRID:AB_439694

      DOI: 10.1016/j.isci.2024.110250

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    ncbi.nlm.nih.gov/pmc/articles/PMC11253511/
  9. www.sciencedirect.com www.sciencedirect.com
    Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.cell.2024.06.007

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    sciencedirect.com/science/article/pii/S0092867424006470
  10. www.sciencedirect.com www.sciencedirect.com
    Promotion of seedling germination in Arabidopsis by B-box zinc-finger protein BBX32
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.cub.2024.06.014

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    sciencedirect.com/science/article/pii/S0960982224007668
  11. Jun 2024
  12. www.cell.com www.cell.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.002

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    cell.com/cell/fulltext/S0092-8674(24)00493-8
  13. Apr 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse
    1
    1. scibot 30 Apr 2024
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      DOI: 10.7554/eLife.93131

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    ncbi.nlm.nih.gov/pmc/articles/PMC11052572/
  15. www.sciencedirect.com www.sciencedirect.com
    ISGylation by HERCs facilitates STING activation
    1
    1. scibot 23 Apr 2024
      RRID:AB_439694

      DOI: 10.1016/j.celrep.2024.114135

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    sciencedirect.com/science/article/pii/S2211124724004637
  16. Feb 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF3A tail domain phosphorylation is not required for ciliogenesis in mouse embryonic fibroblasts
    1
    1. scibot 28 Feb 2024
      RRID:AB_439694

      DOI: 10.1016/j.isci.2024.109149

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    ncbi.nlm.nih.gov/pmc/articles/PMC10884758/
  18. www.sciencedirect.com www.sciencedirect.com
    Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113740

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    sciencedirect.com/science/article/pii/S2211124724000688
  19. www.sciencedirect.com www.sciencedirect.com
    Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils
    1
    1. scibot 02 Feb 2024
      RRID:AB_439694

      DOI: 10.1016/j.molcel.2024.01.005

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    sciencedirect.com/science/article/pii/S1097276524000066
  20. Jan 2024
  21. www.sciencedirect.com www.sciencedirect.com
    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
    1
    1. scibot 25 Jan 2024
      RRID:AB_439694

      DOI: 10.1016/j.molcel.2023.12.041

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    sciencedirect.com/science/article/pii/S1097276523011218
  22. www.sciencedirect.com www.sciencedirect.com
    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
    1
    1. scibot 06 Jan 2024
      RRID:AB_439694

      DOI: 10.1016/j.celrep.2023.113641

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    sciencedirect.com/science/article/pii/S2211124723016522
  23. Dec 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
    1
    1. scibot 22 Dec 2023
      RRID:AB_439694

      DOI: 10.1016/j.neuron.2023.11.020

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    sciencedirect.com/science/article/pii/S0896627323008942
  25. Nov 2023
  26. www.sciencedirect.com www.sciencedirect.com
    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113434

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    sciencedirect.com/science/article/pii/S2211124723014468
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
    1
    1. scibot 15 Nov 2023
      RRID:AB_439694

      DOI: 10.1038/s41467-023-43027-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10640587/
  28. www.sciencedirect.com www.sciencedirect.com
    V-ATPase recruitment to ER exit sites switches COPII-mediated transport to lysosomal degradation
    1
    1. scibot 03 Nov 2023
      RRID:AB_439694

      DOI: 10.1016/j.devcel.2023.10.007

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    sciencedirect.com/science/article/pii/S1534580723005269
  29. Oct 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schlafen-5 inhibits LINE-1 retrotransposition
    1
    1. scibot 07 Oct 2023
      RRID:AB_439694

      DOI: 10.1016/j.isci.2023.107968

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    ncbi.nlm.nih.gov/pmc/articles/PMC10551903/
  31. www.sciencedirect.com www.sciencedirect.com
    CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation
    1
    1. scibot 06 Oct 2023
      RRID:AB_439694

      DOI: 10.1016/j.celrep.2023.113197

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    sciencedirect.com/science/article/pii/S2211124723012093
  32. Aug 2023
  33. www.nature.com www.nature.com
    Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons
    1
    1. scibot 17 Aug 2023
      RRID:AB_439694

      DOI: 10.1038/s42003-023-05223-0

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    nature.com/articles/s42003-023-05223-0
  34. May 2023
  35. 52.53.155.43 52.53.155.43
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
    1
    1. scibot 25 May 2023
      M4439

      DOI: 10.1101/2023.03.06.531323

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    52.53.155.43/6d6e42f4ace892f9f8318210e37bdd24819e1a2c/2023.03.06.531323v2.full-html.html
  36. Mar 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
    1
    1. scibot 26 Mar 2023
      RRID:AB_439694

      DOI: 10.1016/j.isci.2023.106313

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    ncbi.nlm.nih.gov/pmc/articles/PMC10034470/
  38. www.sciencedirect.com www.sciencedirect.com
    Inter-axonal molecular crosstalk via Lumican proteoglycan sculpts murine cervical corticospinal innervation by distinct subpopulations
    1
    1. scibot 22 Mar 2023
      RRID:AB_439694

      DOI: 10.1016/j.celrep.2023.112182

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    sciencedirect.com/science/article/pii/S2211124723001936
  39. www.sciencedirect.com www.sciencedirect.com
    Sensory circuitry controls cytosolic calcium-mediated phytochrome B phototransduction
    1
    1. scibot 17 Mar 2023
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      DOI: 10.1016/j.cell.2023.02.011

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    sciencedirect.com/science/article/pii/S0092867423001289
  40. Nov 2022
  41. www.sciencedirect.com www.sciencedirect.com
    MPS1 localizes to end-on microtubule-attached kinetochores to promote microtubule release
    1
    1. scibot 17 Nov 2022
      RRID:AB_439694

      DOI: 10.1016/j.cub.2022.10.047

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    sciencedirect.com/science/article/pii/S0960982222016955
  42. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Septin 9 controls CCNB1 stabilization via APC/CCDC20 during meiotic metaphase I/anaphase I transition in mouse oocytes
    1
    1. scibot 11 Nov 2022
      RRID:AB_439694

      DOI: 10.1111/cpr.13359

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    onlinelibrary.wiley.com/doi/10.1111/cpr.13359
  43. Aug 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain
    1
    1. scibot 26 Aug 2022
      RRID:AB_439694

      DOI: 10.1126/sciadv.abo5633

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    ncbi.nlm.nih.gov/pmc/articles/PMC9348805/
  45. www.sciencedirect.com www.sciencedirect.com
    Molecular conflicts disrupting centromere maintenance contribute to Xenopus hybrid inviability
    1
    1. scibot 16 Aug 2022
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      DOI: 10.1016/j.cub.2022.07.037

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    sciencedirect.com/science/article/pii/S0960982222011745
  46. Jun 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
    1
    1. scibot 17 Jun 2022
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      DOI: 10.1016/j.isci.2022.104476

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    sciencedirect.com/science/article/pii/S2589004222007477
  48. Apr 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock
    1
    1. scibot 14 Apr 2022
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      DOI: 10.1016/j.ydbio.2022.04.004

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    sciencedirect.com/science/article/pii/S0012160622000653
  50. www.sciencedirect.com www.sciencedirect.com
    ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
    1
    1. scibot 06 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110598

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    sciencedirect.com/science/article/pii/S2211124722003461
  51. Mar 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Cdc48 influence on separase levels is independent of mitosis and suggests translational sensitivity of separase
    1
    1. scibot 23 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110554

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    sciencedirect.com/science/article/pii/S2211124722002984
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1
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    1. scibot 04 Mar 2022
      RRID:AB_439694WB

      DOI: 10.7554/eLife.57593

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    ncbi.nlm.nih.gov/pmc/articles/PMC8880992/
  54. www.sciencedirect.com www.sciencedirect.com
    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.isci.2022.103813

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    sciencedirect.com/science/article/pii/S2589004222000839
  55. Feb 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae
    1
    1. scibot 16 Feb 2022
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      DOI: 10.7554/eLife.74437

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    ncbi.nlm.nih.gov/pmc/articles/PMC8830886/
  57. Jan 2022
  58. www.sciencedirect.com www.sciencedirect.com
    R-type voltage-gated Ca2+ channels mediate A-type K+ current regulation of synaptic input in hippocampal dendrites
    1
    1. scibot 19 Jan 2022
      RRID:AB_439694

      DOI: 10.1016/j.celrep.2021.110264

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    sciencedirect.com/science/article/pii/S2211124721017769
  59. Dec 2021
  60. www.sciencedirect.com www.sciencedirect.com
    The role of epithelial progesterone receptor isoforms in embryo implantation
    1
    1. scibot 08 Dec 2021
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      DOI: 10.1016/j.isci.2021.103487

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    sciencedirect.com/science/article/pii/S2589004221014589
  61. Nov 2021
  62. www.sciencedirect.com www.sciencedirect.com
    A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae
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    1. scibot 19 Nov 2021
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      DOI: 10.1016/j.cub.2021.10.069

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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  64. Oct 2021
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    S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity
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  66. Sep 2021
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    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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  68. elifesciences.org elifesciences.org
    The amyloid precursor protein is a conserved Wnt receptor
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  69. www.nature.com www.nature.com
    Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening
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  70. Aug 2021
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    Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival
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  73. www.biorxiv.org www.biorxiv.org
    STXBP5/tomosyn regulates both the small Rho GTPase and the surface expression of AMPA receptors to control the dendritic stability of neurons
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  74. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Tyrosine Phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CACHD1 is an α2δ-Like Protein That Modulates CaV3 Voltage-Gated Calcium Channel Activity
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    A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
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  80. Jul 2021
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  82. europepmc.org europepmc.org
    Context-dependent deposition and regulation of mRNAs in P-bodies.
    2
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  83. www.sciencedirect.com www.sciencedirect.com
    A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
    1
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    Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration
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  85. rupress.org rupress.org
    TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi
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  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Septin 4 controls CCNB1 stabilization via APC/CCDC20 during meiotic G2/M transition in mouse oocytes
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  88. Jun 2021
  89. www.sciencedirect.com www.sciencedirect.com
    An Hsp90 co-chaperone links protein folding and degradation and is part of a conserved protein quality control
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    Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia
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  91. May 2021
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth
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  93. www.sciencedirect.com www.sciencedirect.com
    Overlapping Activities of ELAV/Hu Family RNA Binding Proteins Specify the Extended Neuronal 3′ UTR Landscape in Drosophila
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  94. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TMPRSS11a is a novel age‐altered, tissue specific regulator of migration and wound healing
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  95. Mar 2021
  96. www.nature.com www.nature.com
    Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain
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  98. Feb 2021
  99. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    KCTD5, a novel TRPM4‐regulatory protein required for cell migration as a new predictor for breast cancer prognosis
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  100. Dec 2020
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS
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  102. Oct 2020
  103. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation
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  104. Sep 2020
  105. www.nature.com www.nature.com
    Generation of synthetic nanobodies against delicate proteins
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  106. rupress.org rupress.org
    GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508
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  107. www.sciencedirect.com www.sciencedirect.com
    Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo
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    Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Requirement for US28 During Cytomegalovirus Latency Is Independent of US27 and US29 Gene Expression
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    Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation
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    14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation
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  112. Jan 2020
  113. www.sciencedirect.com www.sciencedirect.com
    Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast
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    ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection
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    Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in Drosophila
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      DOI: 10.1523/JNEUROSCI.1833-18.2019

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  116. www.sciencedirect.com www.sciencedirect.com
    Oligomerization and Photo-Deoligomerization of HOOKLESS1 Controls Plant Differential Cell Growth
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  117. www.nature.com www.nature.com
    Rif1 S- acylation mediates DNA double-strand break repair at the inner nuclear membrane
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  118. www.sciencedirect.com www.sciencedirect.com
    3′ Uridylation Confers miRNAs with Non-canonical Target Repertoires
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  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lack of PDZD7 long isoform disrupts ankle‐link complex and causes hearing loss in mice
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      DOI: 10.1096/fj.201901657RR

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  120. www.sciencedirect.com www.sciencedirect.com
    The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation
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      DOI: 10.1016/j.celrep.2019.10.065

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  121. www.sciencedirect.com www.sciencedirect.com
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  123. www.sciencedirect.com www.sciencedirect.com
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  124. journals.plos.org journals.plos.org
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  126. Nov 2018
  127. www.sciencedirect.com www.sciencedirect.com
    Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression
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    Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  130. www.sciencedirect.com www.sciencedirect.com
    MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
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    FUS Regulates Activity of MicroRNA-Mediated Gene Silencing
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    Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells
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  133. www.sciencedirect.com www.sciencedirect.com
    MPK3- and MPK6-Mediated ICE1 Phosphorylation Negatively Regulates ICE1 Stability and Freezing Tolerance in Arabidopsis
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    Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons
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  135. www.sciencedirect.com www.sciencedirect.com
    The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
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  136. Nov 2017
  137. www.sciencedirect.com www.sciencedirect.com
    The Kinetochore Receptor for the Cohesin Loading Complex
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  138. www.sciencedirect.com www.sciencedirect.com
    Retrograde Synaptic Inhibition Is Mediated by α-Neurexin Binding to the α2δ Subunits of N-Type Calcium Channels
    1
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  139. www.sciencedirect.com www.sciencedirect.com
    Plasma Membrane CRPK1-Mediated Phosphorylation of 14-3-3 Proteins Induces Their Nuclear Import to Fine-Tune CBF Signaling during Cold Response
    1
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      Curator: @Zeljana_Babic

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    The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs
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  142. www.sciencedirect.com www.sciencedirect.com
    Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1
    1
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    A Rapid Induction Mechanism for Lin28a in Trophic Responses
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mechanism of Regulated Release of Lasso/Teneurin-2
    1
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