69 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification
    1
    1. scibot 02 May 2024
      RRID:AB_441965

      DOI: 10.1016/j.immuni.2024.04.007

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    sciencedirect.com/science/article/pii/S1074761324002127
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114024

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    sciencedirect.com/science/article/pii/S2211124724003528
  5. Jan 2024
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    PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.015

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    sciencedirect.com/science/article/pii/S1534580723006962
  7. Dec 2023
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    Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome
    1
    1. scibot 22 Dec 2023
      RRID:AB_441965

      DOI: 10.1016/j.cell.2023.11.019

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    sciencedirect.com/science/article/pii/S0092867423012734
  9. Nov 2023
  10. www.biorxiv.org www.biorxiv.org
    Endonucleosis mediates internalization of cytoplasm into the nucleus in senescent cells
    1
    1. scibot 17 Nov 2023
      RRID:AB_441965

      DOI: 10.1101/2023.11.12.566736

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    biorxiv.org/content/10.1101/2023.11.12.566736v1
  11. Jun 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.004

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    sciencedirect.com/science/article/pii/S1074761323002212
  13. Apr 2023
  14. www.sciencedirect.com www.sciencedirect.com
    DNA architectural protein CTCF facilitates subset-specific chromatin interactions to limit the formation of memory CD8+ T cells
    1
    1. scibot 12 Apr 2023
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      DOI: 10.1016/j.immuni.2023.03.017

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    sciencedirect.com/science/article/abs/pii/S1074761323001371
  15. Mar 2023
  16. www.sciencedirect.com www.sciencedirect.com
    HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression
    1
    1. scibot 23 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112284

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    sciencedirect.com/science/article/pii/S2211124723002954
  17. Feb 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Low affinity CTCF binding drives transcriptional regulation whereas high affinity binding encompasses architectural functions
    1
    1. scibot 17 Feb 2023
      RRID:AB_441965

      DOI: 10.1016/j.isci.2023.106106

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    sciencedirect.com/science/article/pii/S2589004223001839
  19. Jan 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Principles of 3D chromosome folding and evolutionary genome reshuffling in mammals
    1
    1. scibot 28 Jan 2023
      RRID:AB_441965

      DOI: 10.1016/j.celrep.2022.111839

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    sciencedirect.com/science/article/pii/S2211124722017314
  21. www.sciencedirect.com www.sciencedirect.com
    Human SMARCA5 is continuously required to maintain nucleosome spacing
    1
    1. scibot 12 Jan 2023
      RRID:AB_441965

      DOI: 10.1016/j.molcel.2022.12.018

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    sciencedirect.com/science/article/pii/S1097276522011753
  22. Nov 2022
  23. www.sciencedirect.com www.sciencedirect.com
    Essential role of MESP1-RING1A complex in cardiac differentiation
    1
    1. scibot 22 Nov 2022
      RRID:AB_441965

      DOI: 10.1016/j.devcel.2022.10.009

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    sciencedirect.com/science/article/pii/S1534580722007614
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
    1
    1. scibot 02 Nov 2022
      RRID:AB_441965

      DOI: 10.1158/0008-5472.CAN-22-0671

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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
  25. Oct 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Establishment of 3D chromatin structure after fertilization and the metabolic switch at the morula-to-blastocyst transition require CTCF
    1
    1. scibot 20 Oct 2022
      RRID:AB_441965

      DOI: 10.1016/j.celrep.2022.111501

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    sciencedirect.com/science/article/pii/S2211124722013511
  27. Sep 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions
    1
    1. scibot 22 Sep 2022
      RRID:AB_441965

      DOI: 10.1016/j.isci.2022.105011

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    ncbi.nlm.nih.gov/pmc/articles/PMC9474293/
  29. Jun 2022
  30. www.nature.com www.nature.com
    TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors
    1
    1. scibot 22 Jun 2022
      RRID:AB_441965

      DOI: 10.1038/s41590-022-01232-z

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    nature.com/articles/s41590-022-01232-z
  31. May 2022
  32. www.nature.com www.nature.com
    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
    1
    1. scibot 26 May 2022
      RRID:AB_441965

      DOI: 10.1038/s41598-022-12188-3

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    nature.com/articles/s41598-022-12188-3
  33. Apr 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Il6 expression by single CpG methylation in downstream of Il6 transcription initiation site
    1
    1. scibot 08 Apr 2022
      RRID:AB_441965

      DOI: 10.1016/j.isci.2022.104118

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983349/
  35. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
    1
    1. scibot 07 Apr 2022
      AB_441965

      DOI: 10.1016/j.celrep.2022.110637

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    sciencedirect.com/science/article/pii/S2211124722003898
  36. Feb 2022
  37. www.sciencedirect.com www.sciencedirect.com
    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
    1
    1. scibot 23 Feb 2022
      RRID:AB_441965

      DOI: 10.1016/j.molcel.2022.01.015

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    sciencedirect.com/science/article/pii/S1097276522000582
  38. Nov 2021
  39. www.sciencedirect.com www.sciencedirect.com
    An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity
    1
    1. scibot 02 Nov 2021
      RRID:AB_441965

      DOI: 10.1016/j.neuron.2021.10.014

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    sciencedirect.com/science/article/pii/S0896627321007820
  40. Sep 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Manipulation of TAD reorganization by chemical-dependent genome linking
    1
    1. scibot 09 Sep 2021
      RRID:AB_441965

      DOI: 10.1016/j.xpro.2021.100799

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    sciencedirect.com/science/article/pii/S2666166721005050
  42. Aug 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
      RRID:AB_441965

      DOI: 10.1016/j.molcel.2018.11.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC6344341/
  44. Jul 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:AB_441965

      DOI: 10.1016/j.immuni.2018.12.014

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    sciencedirect.com/science/article/pii/S1074761318305624
  46. www.sciencedirect.com www.sciencedirect.com
    A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers
    1
    1. scibot 29 Jul 2021
      RRID: AB_441965

      DOI: 10.1016/j.cell.2019.07.011

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    sciencedirect.com/science/article/pii/S0092867419307767
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis
    1
    1. scibot 29 Jul 2021
      RRID:AB_441965

      DOI: 10.1016/j.celrep.2019.06.037

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    ncbi.nlm.nih.gov/pmc/articles/PMC6635386/
  48. www.nature.com www.nature.com
    Untitled document
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    1. scibot 29 Jul 2021
      RRID:AB_441965

      DOI: 10.1038/s41586-018-0845-0

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    nature.com/articles/s41586-018-0845-0 
  49. www.sciencedirect.com www.sciencedirect.com
    Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency
    1
    1. scibot 27 Jul 2021
      RRID:AB_441965

      DOI: 10.1016/j.cels.2018.09.003

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    sciencedirect.com/science/article/pii/S2405471218303892
  50. www.sciencedirect.com www.sciencedirect.com
    Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet
    1
    1. scibot 27 Jul 2021
      AB_441965

      DOI: 10.1016/j.nbd.2014.09.014

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    sciencedirect.com/science/article/pii/S0969996114002861
  51. www.sciencedirect.com www.sciencedirect.com
    Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression
    1
    1. scibot 01 Jul 2021
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      DOI: 10.1016/j.molcel.2021.06.008

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    sciencedirect.com/science/article/pii/S109727652100455X
  52. Jun 2021
  53. www.frontiersin.org www.frontiersin.org
    NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression
    1
    1. scibot 26 Jun 2021
      RRID:AB_441965

      DOI: 10.3389/fimmu.2021.668369

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    frontiersin.org/article/10.3389/fimmu.2021.668369/full
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suv4-20h2 protects against influenza virus infection by suppression of chromatin loop formation
    1
    1. scibot 26 Jun 2021
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      DOI: 10.1016/j.isci.2021.102660

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    ncbi.nlm.nih.gov/pmc/articles/PMC8209278/
  55. May 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions
    1
    1. scibot 26 May 2021
      RRID:AB_441965

      DOI: 10.1016/j.stem.2021.04.023

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    sciencedirect.com/science/article/pii/S1934590921001818
  57. www.nature.com www.nature.com
    Transcription factor chromatin profiling genome-wide using uliCUT&RUN in single cells and individual blastocysts
    1
    1. scibot 05 May 2021
      RRID:AB_441965

      DOI: 10.1038/s41596-021-00516-2

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    nature.com/articles/s41596-021-00516-2
  58. Feb 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
    1
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      RRID:AB_441965

      DOI: 10.1016/j.celrep.2021.108783

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    sciencedirect.com/science/article/pii/S2211124721000966
  60. www.sciencedirect.com www.sciencedirect.com
    Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
    1
    1. scibot 09 Feb 2021
      RRID:AB_441965

      DOI: 10.1016/j.celrep.2021.108703

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    sciencedirect.com/science/article/pii/S2211124721000164
  61. Nov 2020
  62. www.sciencedirect.com www.sciencedirect.com
    CTCF-Mediated Genome Architecture Regulates the Dosage of Mitotically Stable Mono-allelic Expression of Autosomal Genes
    1
    1. scibot 05 Nov 2020
      RRID:AB_441965

      DOI: 10.1016/j.celrep.2020.108302

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    sciencedirect.com/science/article/pii/S2211124720312912
  63. Sep 2020
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Controlling gene activation by enhancers through a drug-inducible topological insulator
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    1. scibot 23 Sep 2020
      RRID:AB_441965

      DOI: 10.7554/eLife.47980

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    ncbi.nlm.nih.gov/pmc/articles/PMC7200164/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL
    1
    1. scibot 16 Sep 2020
      RRID:AB_441965

      DOI: 10.7554/eLife.52091

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    ncbi.nlm.nih.gov/pmc/articles/PMC7054000/
  66. www.cell.com www.cell.com
    Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability
    1
    1. scibot 15 Sep 2020
      RRID:AB_441965

      DOI: 10.1016/j.molcel.2018.11.001

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    cell.com/molecular-cell/abstract/S1097-2765(18)30943-2
  67. www.sciencedirect.com www.sciencedirect.com
    Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression
    1
    1. scibot 06 Sep 2020
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      DOI: 10.1016/j.immuni.2020.01.003

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  68. Jan 2020
  69. www.sciencedirect.com www.sciencedirect.com
    RNA Interactions Are Essential for CTCF-Mediated Genome Organization
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      DOI: 10.1016/j.molcel.2019.08.015

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  70. www.sciencedirect.com www.sciencedirect.com
    The lncRNA Locus Handsdown Regulates Cardiac Gene Programs and Is Essential for Early Mouse Development
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      DOI: 10.1016/j.devcel.2019.07.013

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Absolute quantification of cohesin, CTCF and their regulators in human cells
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      DOI: 10.7554/eLife.46269

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  72. www.sciencedirect.com www.sciencedirect.com
    Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity
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      DOI: 10.1016/j.molcel.2019.04.030

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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis
    1
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      DOI: 10.1016/j.celrep.2019.06.037

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  74. www.sciencedirect.com www.sciencedirect.com
    Pioneer Factor-Nucleosome Binding Events during Differentiation Are Motif Encoded
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      DOI: 10.1016/j.molcel.2019.05.025

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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved CUT&RUN chromatin profiling tools
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    1. scibot 13 Jan 2020
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      DOI: 10.7554/eLife.46314

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  76. www.sciencedirect.com www.sciencedirect.com
    SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation
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      DOI: 10.1016/j.celrep.2019.06.027

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    Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
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      DOI: 10.1016/j.cmet.2019.08.003

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  78. www.sciencedirect.com www.sciencedirect.com
    Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.07.039

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  79. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.immuni.2018.12.014

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    Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
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      DOI: 10.1016/j.molcel.2019.01.006

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  81. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cell.2019.03.014

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    sciencedirect.com/science/article/pii/S0092867419302764
  82. www.nature.com www.nature.com
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      DOI: 10.1038/s41586-018-0845-0

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  83. Nov 2018
  84. www.sciencedirect.com www.sciencedirect.com
    Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries
    1
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  86. elifesciences.org elifesciences.org
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    elifesciences.org/articles/36245
  87. elifesciences.org elifesciences.org
    Computational prediction of CTCF/cohesin-based intra-TAD loops that insulate chromatin contacts and gene expression in mouse liver
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  88. www.sciencedirect.com www.sciencedirect.com
    CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch
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  90. Nov 2017
  91. www.sciencedirect.com www.sciencedirect.com
    CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression
    1
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  92. www.sciencedirect.com www.sciencedirect.com
    Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate
    1
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    Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development
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    Genome Organization Drives Chromosome Fragility
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867417307183
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    Dynamic Rewiring of Promoter-Anchored Chromatin Loops during Adipocyte Differentiation
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  96. www.sciencedirect.com www.sciencedirect.com
    The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries
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    sciencedirect.com/science/article/pii/S1097276517301648
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    Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region
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    sciencedirect.com/science/article/pii/S1074761316303363
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    Editing DNA Methylation in the Mammalian Genome
    1
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