174 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles
    1
    1. scibot 12 Dec 2024
      RRID:AB_443298

      DOI: 10.1016/j.molcel.2024.11.015

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    sciencedirect.com/science/article/pii/S1097276524009201
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
    1
    1. scibot 16 Nov 2024
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      DOI: 10.1016/j.cell.2024.10.019

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    sciencedirect.com/science/article/pii/S0092867424012017
  5. Sep 2024
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Linking activation of synaptic NMDA receptors-induced CREB signaling to brief exposure of cortical neurons to oligomeric amyloid-beta peptide
    1
    1. scibot 27 Sep 2024
      RRID:AB_443298

      DOI: 10.1111/jnc.16222

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16222
  7. www.sciencedirect.com www.sciencedirect.com
    Metformin decelerates aging clock in male monkeys
    1
    1. scibot 13 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.021

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    sciencedirect.com/science/article/pii/S0092867424009140
  8. Aug 2024
  9. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
    1
    1. scibot 29 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114682

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    sciencedirect.com/science/article/pii/S2211124724010337
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1038/s41467-024-51030-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11344041/
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    Epitranscriptomic reader YTHDF2 regulates SEK1(MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.isci.2024.110619

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    sciencedirect.com/science/article/pii/S2589004224018443
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    Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.xpro.2024.103214

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    sciencedirect.com/science/article/pii/S2666166724003794
  13. Jul 2024
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
    1
    1. scibot 23 Jul 2024
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      DOI: 10.1111/acel.14258

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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
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    SHP2 mutations promote glycolysis and inhibit apoptosis via PKM2/hnRNPK signaling in colorectal cancer
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.isci.2024.110462

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    sciencedirect.com/science/article/pii/S2589004224016870
  16. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101647

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    sciencedirect.com/science/article/pii/S2666379124003616
  17. Jun 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Impaired Tryptophan Metabolism by Type 2 Inflammation in Epithelium Worsening Asthma
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109923

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    sciencedirect.com/science/article/pii/S2589004224011453
  19. May 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
    2
    1. scibot 31 May 2024
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      DOI: 10.1016/j.ccell.2024.05.006

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    2. scibot 31 May 2024
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      DOI: 10.1016/j.ccell.2024.05.006

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    sciencedirect.com/science/article/pii/S1535610824001697
  21. 52.53.155.43 52.53.155.43
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
    2
    1. scibot 17 May 2024
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      DOI: 10.20944/preprints202402.1027.v1

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      DOI: 10.20944/preprints202402.1027.v1

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    52.53.155.43/86d6d1effc82110b06a7585d839c944adff76cc8/preprints202402.1027.v1-html.html
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention
    1
    1. scibot 15 May 2024
      RRID:AB_443298

      DOI: 10.4103/1673-5374.390966

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    ncbi.nlm.nih.gov/pmc/articles/PMC11090426/
  23. Apr 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
    1
    1. scibot 03 Apr 2024
      RRID:AB_443298

      DOI: 10.3390/ijms25063343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
  25. Mar 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
    1
    1. scibot 22 Mar 2024
      RRID:AB_443298

      DOI: 10.1016/j.isci.2024.109343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951912/
  27. www.sciencedirect.com www.sciencedirect.com
    The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA
    2
    1. scibot 14 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.008

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    2. scibot 14 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.008

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    sciencedirect.com/science/article/pii/S1534580724001072
  28. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
    1
    1. scibot 08 Mar 2024
      RRID:AB_443298

      DOI: 10.1016/j.molcel.2023.12.033

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    sciencedirect.com/science/article/pii/S1097276523010791
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    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
    1
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.bbadis.2024.167116

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    sciencedirect.com/science/article/pii/S0925443924001054
  30. www.sciencedirect.com www.sciencedirect.com
    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109231

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      DOI: 10.1016/j.isci.2024.109231

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    sciencedirect.com/science/article/pii/S2589004224004528
  31. www.sciencedirect.com www.sciencedirect.com
    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113912

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    sciencedirect.com/science/article/pii/S2211124724002407
  32. Feb 2024
  33. www.jneurosci.org www.jneurosci.org
    Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1523/JNEUROSCI.1665-23.2023

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    jneurosci.org/content/44/7/e1665232023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cullin-RING E3 ubiquitin ligase 4 regulates neurite morphogenesis during neurodevelopment
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108933

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839267/
  35. Jan 2024
  36. 52.53.155.43 52.53.155.43
    JNEUROSCI.1665-23.2023.full-html.html
    2
    1. scibot 26 Jan 2024
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      DOI: 10.1523/jneurosci.1665-23.2023

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      DOI: 10.1523/jneurosci.1665-23.2023

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    52.53.155.43/9add5f7e7c84e06696c302815bac67f6cb4d2d58/JNEUROSCI.1665-23.2023.full (1)-html.html
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
    1
    1. scibot 14 Jan 2024
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      DOI: 10.1016/j.isci.2023.108655

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    ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
  38. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
    1
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      DOI: 10.1016/j.stem.2023.12.002

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    sciencedirect.com/science/article/pii/S1934590923004320
  39. link.springer.com link.springer.com
    Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
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      DOI: 10.1038/s41467-024-44687-4

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    link.springer.com/article/10.1038/s41467-024-44687-4
  40. www.sciencedirect.com www.sciencedirect.com
    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
    1
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      DOI: 10.1016/j.celrep.2023.113626

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    sciencedirect.com/science/article/pii/S2211124723016376
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
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      DOI: 10.1083/jcb.202304026

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    ncbi.nlm.nih.gov/pmc/articles/PMC10309186/
  42. Dec 2023
  43. www.sciencedirect.com www.sciencedirect.com
    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
    1
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      DOI: 10.1016/j.isci.2023.108568

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    sciencedirect.com/science/article/pii/S2589004223026457
  44. www.sciencedirect.com www.sciencedirect.com
    TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
    1
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      DOI: 10.1016/j.isci.2023.108617

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    sciencedirect.com/science/article/pii/S2589004223026949
  45. Nov 2023
  46. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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      DOI: 10.1016/j.molcel.2023.10.008

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    sciencedirect.com/science/article/pii/S1097276523008420
  47. www.sciencedirect.com www.sciencedirect.com
    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
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      DOI: 10.1016/j.molcel.2023.10.017

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    sciencedirect.com/science/article/pii/S1097276523008547
  48. www.sciencedirect.com www.sciencedirect.com
    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
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      DOI: 10.1016/j.celrep.2023.113478

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    sciencedirect.com/science/article/pii/S2211124723014900
  49. www.biorxiv.org www.biorxiv.org
    Endonucleosis mediates internalization of cytoplasm into the nucleus in senescent cells
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      DOI: 10.1101/2023.11.12.566736

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    biorxiv.org/content/10.1101/2023.11.12.566736v1
  50. Oct 2023
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    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    Deep learning enables STORM-like superresolution image reconstruction from conventional microscopy
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    Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells
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    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
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    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  57. Sep 2023
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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  63. Jul 2023
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    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    Generation of mouse hippocampal brain organoids from primary embryonic neural stem cells
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    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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  67. Jun 2023
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    Ex vivo immunocapture and functional characterization of cell-type-specific mitochondria using MitoTag mice
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    Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation
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    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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    Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging
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  72. May 2023
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    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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  75. Apr 2023
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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    High-resolution confocal and light-sheet imaging of collagen 3D network architecture in very large samples
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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  79. Mar 2023
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    Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate
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    hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease
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    Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery
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  85. Dec 2022
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    Connections between sister and non-sister telomeres of segregating chromatids maintain euploidy
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    Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
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    Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability
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  105. May 2022
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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  112. Apr 2022
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    Long-term Hyperandrogenemia and/or Western-style Diet in Rhesus Macaque Females Impairs Preimplantation Embryogenesis
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    Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function
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    Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories
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  117. Feb 2022
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    Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration
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  121. Jan 2022
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    Vitamin D receptor, STAT3, and TET2 cooperate to establish tolerogenesis
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  123. Dec 2021
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    Contribution of Brain Processes to Tissue Loss After Spinal Cord Injury: Does a Pain-Induced Rise in Blood Pressure Fuel Hemorrhage?
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  126. Nov 2021
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    The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
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  128. Oct 2021
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    Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
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  130. Sep 2021
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    The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
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  132. Aug 2021
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    RNF8 is not required for histone-to-protamine exchange in spermiogenesis
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    Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm
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    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
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  144. Jul 2021
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    TIMELESS mutation alters phase responsiveness and causes advanced sleep phase
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    Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium
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  152. May 2021
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    In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
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    Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
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    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
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    FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
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    Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation
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    HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70
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    Engaging pain fibers after a spinal cord injury fosters hemorrhage and expands the area of secondary injury
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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      (Abcam Cat# ab16048, RRID:AB_443298)

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      RRID:AB_443298
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    sciencedirect.com/science/article/pii/S0092867418303052
  208. www.sciencedirect.com www.sciencedirect.com
    A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response
    1
    1. scibot 05 Nov 2018
      RRID:AB_443298

      Curator: @Jmenke

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      (Abcam Cat# ab16048, RRID:AB_443298)

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      RRID:AB_443298 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418301090
  209. www.sciencedirect.com www.sciencedirect.com
    HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types
    1
    1. scibot 05 Nov 2018
      RRID:AB_443298

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      (Abcam Cat# ab16048, RRID:AB_443298)

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    sciencedirect.com/science/article/pii/S1097276518302338
  210. www.sciencedirect.com www.sciencedirect.com
    Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport
    1
    1. scibot 05 Nov 2018
      RRID:AB_443298

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      (Abcam Cat# ab16048, RRID:AB_443298)

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    sciencedirect.com/science/article/pii/S1931312818301380
  211. www.sciencedirect.com www.sciencedirect.com
    Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice
    1
    1. scibot 05 Nov 2018
      RRID:AB_443298

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      (Abcam Cat# ab16048, RRID:AB_443298)

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    sciencedirect.com/science/article/pii/S2451945618300072
  212. www.sciencedirect.com www.sciencedirect.com
    Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
    1
    1. scibot 05 Nov 2018
      RRID:AB_443298

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      (Abcam Cat# ab16048, RRID:AB_443298)

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    sciencedirect.com/science/article/pii/S1097276517307001
  213. Nov 2017
  214. elifesciences.org elifesciences.org
    Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology
    1
    1. scibot 08 Nov 2017
      RRID:AB_443298

      Curator: @kaitlinsung

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      (Abcam Cat# ab16048, RRID:AB_443298)

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    elifesciences.org/articles/28202
  215. www.sciencedirect.com www.sciencedirect.com
    The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines
    1
    1. scibot 08 Nov 2017
      RRID:AB_443298

      Curator: @Jmenke

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      (Abcam Cat# ab16048, RRID:AB_443298)

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      RRID:AB_443298 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945617302337
  216. www.sciencedirect.com www.sciencedirect.com
    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
    1
    1. scibot 08 Nov 2017
      AB_443298

      Curator: @kaitlinsung

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      (Abcam Cat# ab16048, RRID:AB_443298)

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      RRID:AB_443298 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117300943
  217. elifesciences.org elifesciences.org
    KChIP2 is a core transcriptional regulator of cardiac excitability
    1
    1. scibot 08 Nov 2017
      AB_443298

      Curator: @gabimpine

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      (Abcam Cat# ab16048, RRID:AB_443298)

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      RRID:AB_443298 RRIDCUR:Validated
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    elifesciences.org/content/6/e17304
  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation
    2
    1. scibot 08 Nov 2017
      AB_443298

      Curator: @kaitlinsung

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      (Abcam Cat# ab16048, RRID:AB_443298)

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      RRID:AB_443298 RRIDCUR:Validated
    2. scibot 08 Nov 2017
      AB_443298

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      (Abcam Cat# ab16048, RRID:AB_443298)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5050025/