168 Matching Annotations
  1. Last 7 days
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    Epitranscriptomic reader YTHDF2 regulates SEK1(MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress
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    sciencedirect.com/science/article/pii/S2589004224018443
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    Protocol for machine-learning-based 3D image analysis of nuclear envelope tubules in cultured cells
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    sciencedirect.com/science/article/pii/S2666166724003794
  4. Jul 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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      DOI: 10.1111/acel.14258

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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
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    SHP2 mutations promote glycolysis and inhibit apoptosis via PKM2/hnRNPK signaling in colorectal cancer
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    sciencedirect.com/science/article/pii/S2589004224016870
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    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
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    sciencedirect.com/science/article/pii/S2666379124003616
  8. Jun 2024
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    Impaired Tryptophan Metabolism by Type 2 Inflammation in Epithelium Worsening Asthma
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    sciencedirect.com/science/article/pii/S2589004224011453
  10. May 2024
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    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  12. 52.53.155.43 52.53.155.43
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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      DOI: 10.20944/preprints202402.1027.v1

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      DOI: 10.20944/preprints202402.1027.v1

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    52.53.155.43/86d6d1effc82110b06a7585d839c944adff76cc8/preprints202402.1027.v1-html.html
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention
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    1. scibot 15 May 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090426/
  14. Apr 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    1. scibot 03 Apr 2024
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      DOI: 10.3390/ijms25063343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
  16. Mar 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
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    ncbi.nlm.nih.gov/pmc/articles/PMC10951912/
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    The sirtuin-associated human senescence program converges on the activation of placenta-specific gene PAPPA
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    sciencedirect.com/science/article/pii/S1534580724001072
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    Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
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    sciencedirect.com/science/article/pii/S1097276523010791
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    AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway
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    sciencedirect.com/science/article/pii/S0925443924001054
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    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
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    sciencedirect.com/science/article/pii/S2589004224004528
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    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124724002407
  23. Feb 2024
  24. www.jneurosci.org www.jneurosci.org
    Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice
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      DOI: 10.1523/JNEUROSCI.1665-23.2023

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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cullin-RING E3 ubiquitin ligase 4 regulates neurite morphogenesis during neurodevelopment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10839267/
  26. Jan 2024
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    JNEUROSCI.1665-23.2023.full-html.html
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  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct modes of telomere synthesis and extension contribute to Alternative Lengthening of Telomeres
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    ncbi.nlm.nih.gov/pmc/articles/PMC10783591/
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    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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      DOI: 10.1016/j.stem.2023.12.002

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    sciencedirect.com/science/article/pii/S1934590923004320
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    Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
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      DOI: 10.1038/s41467-024-44687-4

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    link.springer.com/article/10.1038/s41467-024-44687-4
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    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
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    sciencedirect.com/science/article/pii/S2211124723016376
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
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      DOI: 10.1083/jcb.202304026

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    ncbi.nlm.nih.gov/pmc/articles/PMC10309186/
  33. Dec 2023
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    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
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    sciencedirect.com/science/article/pii/S2589004223026457
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    TRPC4 deletion elicits behavioral defects in sociability by dysregulating expression of microRNA-138-2
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    sciencedirect.com/science/article/pii/S2589004223026949
  36. Nov 2023
  37. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    sciencedirect.com/science/article/pii/S1097276523008420
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    Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition
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    sciencedirect.com/science/article/pii/S1097276523008547
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    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
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    sciencedirect.com/science/article/pii/S2211124723014900
  40. www.biorxiv.org www.biorxiv.org
    Endonucleosis mediates internalization of cytoplasm into the nucleus in senescent cells
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      DOI: 10.1101/2023.11.12.566736

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    biorxiv.org/content/10.1101/2023.11.12.566736v1
  41. Oct 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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      DOI: 10.1016/j.stem.2023.09.007

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    sciencedirect.com/science/article/pii/S1934590923003284
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep learning enables STORM-like superresolution image reconstruction from conventional microscopy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10587619/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiangiogenic Action of JZL184 on Endothelial Cells via Inhibition of VEGF Expression in Hypoxic Lung Cancer Cells
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      DOI: 10.3390/cells12192332

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    ncbi.nlm.nih.gov/pmc/articles/PMC10572003/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
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      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
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      DOI: 10.1186/s12967-023-04542-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10577912/
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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      DOI: 10.1016/j.molcel.2023.09.023

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  48. Sep 2023
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    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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    Long-term Hyperandrogenemia and/or Western-style Diet in Rhesus Macaque Females Impairs Preimplantation Embryogenesis
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  105. Mar 2022
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    Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories
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  108. Feb 2022
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  112. Jan 2022
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    Contribution of Brain Processes to Tissue Loss After Spinal Cord Injury: Does a Pain-Induced Rise in Blood Pressure Fuel Hemorrhage?
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  117. Nov 2021
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    The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
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  119. Oct 2021
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    Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
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  123. Aug 2021
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    RNF8 is not required for histone-to-protamine exchange in spermiogenesis
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    Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm
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    Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer
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  135. Jul 2021
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    TIMELESS mutation alters phase responsiveness and causes advanced sleep phase
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    Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium
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  143. May 2021
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    In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
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    Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
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  152. Mar 2021
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  154. Feb 2021
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  161. Oct 2020
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    Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
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    PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin
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    Depatuxizumab mafodotin (ABT-414)-induced glioblastoma cell death requires EGFR overexpression, but not EGFRY1068 phosphorylation
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    Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation
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    Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy
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    Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
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    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
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    Engaging pain fibers after a spinal cord injury fosters hemorrhage and expands the area of secondary injury
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    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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    Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown
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    Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport
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    Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells
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    Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology
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      RRID:AB_443298 RRIDCUR:Validated
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    elifesciences.org/articles/28202
  206. www.sciencedirect.com www.sciencedirect.com
    The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines
    1
    1. scibot 08 Nov 2017
      RRID:AB_443298

      Curator: @Jmenke

      Resource used:

      (Abcam Cat# ab16048, RRID:AB_443298)

      SciCrunch record: RRID:AB_443298

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      RRID:AB_443298 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945617302337
  207. www.sciencedirect.com www.sciencedirect.com
    Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation
    1
    1. scibot 08 Nov 2017
      AB_443298

      Curator: @kaitlinsung

      Resource used:

      (Abcam Cat# ab16048, RRID:AB_443298)

      SciCrunch record: RRID:AB_443298

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      RRID:AB_443298 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117300943
  208. elifesciences.org elifesciences.org
    KChIP2 is a core transcriptional regulator of cardiac excitability
    1
    1. scibot 08 Nov 2017
      AB_443298

      Curator: @gabimpine

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      (Abcam Cat# ab16048, RRID:AB_443298)

      SciCrunch record: RRID:AB_443298

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      RRID:AB_443298 RRIDCUR:Validated
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    elifesciences.org/content/6/e17304
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation
    2
    1. scibot 08 Nov 2017
      AB_443298

      Curator: @kaitlinsung

      Resource used:

      (Abcam Cat# ab16048, RRID:AB_443298)

      SciCrunch record: RRID:AB_443298

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_443298 RRIDCUR:Validated
    2. scibot 08 Nov 2017
      AB_443298

      Resource used:

      (Abcam Cat# ab16048, RRID:AB_443298)

      SciCrunch record: RRID:AB_443298

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      RRID:AB_443298
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    ncbi.nlm.nih.gov/pmc/articles/PMC5050025/