112 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9-mediated deletion of carbonic anhydrase 2 in the ciliary body to treat glaucoma
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    sciencedirect.com/science/article/pii/S2666379124001939
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    Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis
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      DOI: 10.1073/pnas.2217877121

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  4. Apr 2024
  5. www.sciencedirect.com www.sciencedirect.com
    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
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    sciencedirect.com/science/article/pii/S1074761324001420
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    Differential squamous cell fates elicited by NRF2 gain of function versus KEAP1 loss of function
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    sciencedirect.com/science/article/pii/S2211124724004327
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
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    sciencedirect.com/science/article/pii/S221112472400442X
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    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424003106
  9. Mar 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rejuvenated iPSC-derived GD2-directed CART Cells Harbor Robust Cytotoxicity Against Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10926899/
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    An immune cell map of human lung adenocarcinoma development reveals an anti-tumoral role of the Tfh-dependent tertiary lymphoid structure
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    sciencedirect.com/science/article/pii/S2666379124000715
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    NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2211124724002262
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FcγRIIB is an immune checkpoint limiting the activity of Treg-targeting antibodies in the tumor microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911703/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Value of carotid intima thickness in assessing advanced carotid plaque vulnerability: a study based on carotid artery ultrasonography and carotid plaque histology
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    ncbi.nlm.nih.gov/pmc/articles/PMC10895139/
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    Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients
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  16. Feb 2024
  17. 52.53.155.43 52.53.155.43
    Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
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    1. scibot 23 Feb 2024
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      DOI: 10.1101/2023.10.11.561653

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    Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
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      DOI: 10.1038/s41467-024-45760-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10873513/
  20. Dec 2023
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    A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas
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    sciencedirect.com/science/article/pii/S153458072300583X
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
    1
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      DOI: 10.1158/2159-8290.CD-23-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
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    The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer
    1
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    Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma
    1
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      DOI: 10.3390/md21120600

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    mdpi.com/1660-3397/21/12/600
  25. Nov 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer
    1
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      DOI: 10.1186/s13059-023-03108-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10680327/
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    Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease
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    sciencedirect.com/science/article/pii/S2589004223023556
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    Spatial metabolomics identifies distinct tumor-specific and stroma-specific subtypes in patients with lung squamous cell carcinoma
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  29. Oct 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
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    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
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    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1535610823003276
  33. 52.53.155.43 52.53.155.43
    noad191-html.html
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    SSRN-id4540281-html.html
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  35. Sep 2023
  36. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Su-html.html
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      DOI: 10.1111/bph.16240

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-dose carboplatin modifies the tumor microenvironment to augment CAR T cell efficacy in human prostate cancer models
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      DOI: 10.1038/s41467-023-40852-3

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  38. Aug 2023
  39. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intratumoral NKp46+ natural killer cells are spatially distanced from T and MHC-I+ cells with prognostic implications in soft tissue sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10401426/
  41. www.sciencedirect.com www.sciencedirect.com
    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610821001094
  42. Jul 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
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      DOI: 10.1016/j.isci.2023.107201

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    sciencedirect.com/science/article/pii/S2589004223012786
  44. www.sciencedirect.com www.sciencedirect.com
    A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma
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      DOI: 10.1016/j.ymthe.2023.06.004

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  45. Jun 2023
  46. dx.doi.org dx.doi.org
    EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression
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    1. scibot 10 Jun 2023
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      DOI: 10.1158/2326-6066.CIR-22-0374

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    dx.doi.org/10.1158/2326-6066.CIR-22-0374
  47. link.springer.com link.springer.com
    Kinesin-5 inhibition improves neural regeneration in experimental autoimmune neuritis
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      DOI: 10.1186/s12974-023-02822-w

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    link.springer.com/article/10.1186/s12974-023-02822-w
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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  49. May 2023
  50. www.sciencedirect.com www.sciencedirect.com
    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
    1
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    A nanotherapeutic strategy that engages cytotoxic and immunosuppressive activities for the treatment of cancer recurrence following organ transplantation
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    Neuronal Adenosine A1 Receptor is Critical for Olfactory Function but Unable to Attenuate Olfactory Dysfunction in Neuroinflammation
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      DOI: 10.3389/fncel.2022.912030

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  53. aacrjournals.org aacrjournals.org
    Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-0410

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  54. Apr 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells
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    Gut dysbiosis promotes the breakdown of oral tolerance mediated through dysfunction of mucosal dendritic cells
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    Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir
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    Phenotypic plasticity and reduced tissue retention of exhausted tumor-infiltrating T cells following neoadjuvant immunotherapy in head and neck cancer
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    Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
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    Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
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    Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade
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  62. Mar 2023
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    Sex Differences in the Systemic and Local Immune Response of Pancreatic Cancer Patients
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    Sensitive magnetic particle imaging of haemoglobin degradation for the detection and monitoring of intraplaque haemorrhage in atherosclerosis
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  65. Feb 2023
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes
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    Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner
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  68. Dec 2022
  69. www.sciencedirect.com www.sciencedirect.com
    A porcine islet-encapsulation device that enables long-term discordant xenotransplantation in immunocompetent diabetic mice
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    Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes
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    Depletion of conventional type-1 dendritic cells in established tumors suppresses immunotherapy efficacy
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  72. 52.53.155.43 52.53.155.43
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  73. Oct 2022
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Underwater instant adhesion mechanism of self-assembled amphiphilic hemostatic granular hydrogel from Andrias davidianus skin secretion
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  75. Sep 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripheral immune signature resembles tumor microenvironment and predicts clinical outcomes in head and neck squamous cell carcinoma
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    Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma
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  78. Aug 2022
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    N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis
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  80. Jul 2022
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    Interleukin-21, acting beyond the immunological synapse, independently controls T follicular helper and germinal center B cells
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    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
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  84. Jun 2022
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    Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes
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    The immune cell atlas of human neuroblastoma
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    Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism
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  88. May 2022
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    Spontaneous Hind Limb Paralysis Due to Acute Precursor B Cell Leukemia in RAG1-deficient Mice
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  90. Apr 2022
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    Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma
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  92. Feb 2022
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    MYC and MIZ1-dependent vesicular transport of double-strand RNA controls immune evasion in pancreatic ductal adenocarcinoma
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    Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
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  95. Jan 2022
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    A Retrospective Study of the Differences in the Induction of Regulatory T Cells Between Adult Patients with Eosinophilic Esophagitis and Gastroesophageal Reflux Disease
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      DOI: 10.1007/s10620-021-07355-x

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    TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures
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  98. Dec 2021
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    CAR-T cells Targeting TSHR Demonstrate Safety and Potent Preclinical Activity Against Differentiated Thyroid Cancer
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  100. Sep 2021
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    Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche
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  102. Aug 2021
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    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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  105. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_443425

      DOI: 10.1016/j.devcel.2018.11.010

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  106. academic.oup.com academic.oup.com
    Deoxycorticosterone/Salt-Mediated Cardiac Inflammation and Fibrosis Are Dependent on Functional CLOCK Signaling in Male Mice
    1
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      AB_443425

      DOI: 10.1210/en.2016-1911

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  107. Jul 2021
  108. www.mdpi.com www.mdpi.com
    Experimental Infection of Pregnant Female Sheep with Zika Virus During Early Gestation
    1
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      rabbit anti-sheep CD3

      DOI: 10.3390/v11090795

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  109. www.sciencedirect.com www.sciencedirect.com
    PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients
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      RRID: AB_443425

      DOI: 10.1016/j.ccell.2018.10.007

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  110. www.mdpi.com www.mdpi.com
    Assessment of Immunological Potential of Glial Restricted Progenitor Graft In Vivo—Is Immunosuppression Mandatory?
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      DOI: 10.3390/cells10071804

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  111. www.sciencedirect.com www.sciencedirect.com
    The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease
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      DOI: 10.1016/j.cmet.2021.06.014

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  112. May 2021
  113. www.sciencedirect.com www.sciencedirect.com
    Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis
    1
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      RRID:AB_443425

      DOI: 10.1016/j.celrep.2021.109168

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  114. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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      RRID:AB_443425

      DOI: 10.1016/j.immuni.2020.06.016

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    sciencedirect.com/science/article/pii/S1074761320302715
  115. Apr 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
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    1. scibot 30 Apr 2021
      RRID:AB_443425

      DOI: 10.1016/j.cmet.2020.12.016

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  117. www.sciencedirect.com www.sciencedirect.com
    Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
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      DOI: 10.1016/j.ccell.2021.03.012

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  118. www.sciencedirect.com www.sciencedirect.com
    CNS-Native Myeloid Cells Drive Immune Suppression in the Brain Metastatic Niche through Cxcl10
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      DOI: 10.1016/j.cell.2020.09.064

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  119. www.sciencedirect.com www.sciencedirect.com
    TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
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      DOI: 10.1016/j.cell.2020.05.049

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  120. www.sciencedirect.com www.sciencedirect.com
    Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
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      DOI: 10.1016/j.ccell.2021.02.007

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  121. Mar 2021
  122. elifesciences.org elifesciences.org
    Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis
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      RRID:AB_443425

      DOI: 10.7554/eLife.61798

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  123. Oct 2020
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CD200‐CD200R1 signaling pathway regulates neuroinflammation after stroke
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      RRID:AB_443425

      DOI: 10.1002/brb3.1882

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  125. Sep 2020
  126. www.sciencedirect.com www.sciencedirect.com
    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
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    1. scibot 09 Sep 2020
      RRID:AB_443425

      DOI: 10.1016/j.cell.2020.03.062

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  127. www.mdpi.com www.mdpi.com
    Experimental Infection of Mid-Gestation Pregnant Female and Intact Male Sheep with Zika Virus
    1
    1. scibot 04 Sep 2020
      rabbit anti-sheep CD3

      DOI: 10.3390/v12030291

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    mdpi.com/1999-4915/12/3/291
  128. Aug 2020
  129. www.jci.org www.jci.org
    Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice
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      RRID:AB_44342

      DOI: 10.1172/JCI138697

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  130. Jan 2020
  131. www.sciencedirect.com www.sciencedirect.com
    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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      RRID:AB_443425

      DOI: 10.1016/j.cell.2019.08.032

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  132. www.sciencedirect.com www.sciencedirect.com
    An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_443425

      DOI: 10.1016/j.ccell.2019.08.008

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    sciencedirect.com/science/article/pii/S1535610819303769
  133. www.sciencedirect.com www.sciencedirect.com
    Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization
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    1. scibot 13 Jan 2020
      RRID:AB_443425

      DOI: 10.1016/j.celrep.2019.09.055

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    sciencedirect.com/science/article/pii/S2211124719312434
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
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      RRID:AB_443425

      DOI: 10.1016/j.ccell.2019.08.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC6853173/
  135. www.sciencedirect.com www.sciencedirect.com
    Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration
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    1. scibot 13 Jan 2020
      RRID:AB_443425

      DOI: 10.1016/j.celrep.2019.10.013

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    sciencedirect.com/science/article/pii/S2211124719313130
  136. www.sciencedirect.com www.sciencedirect.com
    Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease
    1
    1. scibot 13 Jan 2020
      RRID:AB_443425

      DOI: 10.1016/j.immuni.2019.12.004

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    sciencedirect.com/science/article/pii/S1074761319305230
  137. www.sciencedirect.com www.sciencedirect.com
    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
    1
    1. scibot 12 Jan 2020
      RRID:AB_443425

      DOI: 10.1016/j.ccell.2018.10.006

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    sciencedirect.com/science/article/pii/S1535610818304720
  138. Nov 2018
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6179961/
  140. www.sciencedirect.com www.sciencedirect.com
    Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting
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      RRID:AB_443425

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  141. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Histological studies on the development of porcine tonsils after birth
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      AB_443425

      Curator: @anp055

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    onlinelibrary.wiley.com/doi/full/10.1002/jmor.20839
  142. www.sciencedirect.com www.sciencedirect.com
    Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
    1
    1. scibot 05 Nov 2018
      RRID:AB_443425

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    sciencedirect.com/science/article/pii/S0896627318300588
  143. Nov 2017
  144. academic.oup.com academic.oup.com
    Deoxycorticosterone/Salt-Mediated Cardiac Inflammation and Fibrosis Are Dependent on Functional CLOCK Signaling in Male Mice
    1
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      AB_443425

      Curator: @patriciaelyse_

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  145. www.sciencedirect.com www.sciencedirect.com
    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
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      AB_443425

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1535610817302519
  146. www.sciencedirect.com www.sciencedirect.com
    Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region
    1
    1. scibot 08 Nov 2017
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