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81 Matching Annotations

Oct 2025
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CBX4 acetoacetylation as an inhibitory mechanism of HIF-1α activity

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.chembiol.2025.09.005
  
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sciencedirect.com/science/article/pii/S2451945625003009
Aug 2025
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Staphylococcus aureus exploits lipoic acid salvage to combat host oxidative stress

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1. scibot 05 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116095
  
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sciencedirect.com/science/article/pii/S2211124725008666
Jun 2025
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Lipocalin-2 regulates astrocyte-oligodendrocyte interaction to drive post-stroke secondary demyelination

1
1. scibot 24 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115899
  
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sciencedirect.com/science/article/pii/S2211124725006709
Apr 2025
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HLS1 interacts with ATG8 to negatively regulate the ABS3-mediated plant senescence pathway

1
1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115507
  
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sciencedirect.com/science/article/pii/S2211124725002785
Jan 2025
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Redox proteomics reveal a role for peroxiredoxinylation in stress protection

1
1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115224
  
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sciencedirect.com/science/article/pii/S2211124724015754
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Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

1
1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.12.009
  
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sciencedirect.com/science/article/pii/S0092867424014223
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The GhCEWT1-GhCEWT2-GhCes4D/GhCOBL4D module orchestrates plant cell elongation and cell wall thickness

1
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  DOI: 10.1016/j.celrep.2024.115129
  
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cell.com/cell-reports/abstract/S2211-1247(24)01480-3
Sep 2024
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DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair

1
1. scibot 25 Sep 2024
  
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  RRID:AB_423119
  
  DOI: 10.1016/j.celrep.2020.01.014
  
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sciencedirect.com/science/article/pii/S2211124720300231
Aug 2024
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Ca2+-dependent lipid preferences shape synaptotagmin-1 C2A and C2B dynamics: Insights from experiments and simulations

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.str.2024.07.017
  
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sciencedirect.com/science/article/pii/S0969212624002806
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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1038/s44318-024-00164-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
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The fork protection complex promotes parental histone recycling and epigenetic memory

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.017
  
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sciencedirect.com/science/article/pii/S0092867424007773
Jul 2024
www.embopress.org www.embopress.org

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 12 Jul 2024
  
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  DOI: 10.1038/s44318-024-00164-8
  
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embopress.org/doi/10.1038/s44318-024-00164-8
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology

1
1. scibot 27 Jun 2024
  
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  DOI: 10.1016/j.xpro.2024.103129
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11193044/
elifesciences.org elifesciences.org

RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia

1
1. scibot 14 Jun 2024
  
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  DOI: 10.7554/eLife.88375
  
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elifesciences.org/articles/88375
May 2024
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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

2
1. scibot 31 May 2024
  
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  DOI: 10.1016/j.ccell.2024.05.006
  
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  DOI: 10.1016/j.ccell.2024.05.006
  
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sciencedirect.com/science/article/pii/S1535610824001697
Mar 2024
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Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

1
1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113965
  
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sciencedirect.com/science/article/pii/S2211124724002936
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Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity

1
1. scibot 02 Mar 2024
  
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  DOI: 10.1016/j.crmeth.2024.100712
  
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sciencedirect.com/science/article/pii/S2667237524000274
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PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay

2
1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.002
  
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2. scibot 01 Mar 2024
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.ccell.2024.02.002
  
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sciencedirect.com/science/article/pii/S1535610824000461
Feb 2024
aacrjournals.org aacrjournals.org

Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma

2
1. scibot 23 Feb 2024
  
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  DOI: 10.1158/1078-0432.CCR-23-1143
  
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  DOI: 10.1158/1078-0432.CCR-23-1143
  
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aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
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Biophysics of microRNA-34a targeting and its influence on down-regulation

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1. scibot 22 Feb 2024
  
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  DOI: 10.1101/2024.02.14.580117
  
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biorxiv.org/content/10.1101/2024.02.14.580117v1
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The cyclimids: Degron-inspired cereblon binders for targeted protein degradation

1
1. scibot 06 Feb 2024
  
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  DOI: 10.1016/j.chembiol.2024.01.003
  
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sciencedirect.com/science/article/pii/S2451945624000394
Dec 2023
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SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer

1
1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.molcel.2023.11.003
  
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sciencedirect.com/science/article/pii/S109727652300919X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity

1
1. scibot 07 Dec 2023
  
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  DOI: 10.1016/j.xcrm.2023.101266
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10694673/
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ccr-23-1143-html.html

1
1. scibot 01 Dec 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-1143
  
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52.53.155.43/aa509a782208f9df8c6754b69c5c07021388a9c4/ccr-23-1143-html.html
Sep 2023
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Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition

1
1. scibot 30 Sep 2023
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.celrep.2023.113184
  
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sciencedirect.com/science/article/pii/S2211124723011968
Jun 2023
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A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity

1
1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112655
  
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sciencedirect.com/science/article/pii/S2211124723006666
Apr 2023
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A conserved brassinosteroid-mediated BES1-CERP-EXPA3 signaling cascade controls plant cell elongation.

1
1. scibot 20 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112301
  
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sciencedirect.com/science/article/pii/S2211124723003121
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein

1
1. scibot 07 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111964
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9812370/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Prx4 acts as DAMP in shrimp, enhancing bacterial resistance via the toll pathway and prophenoloxidase activation

1
1. scibot 07 Jan 2023
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.isci.2022.105793
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9813724/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Centrosomal Protein 120 Promotes Centrosome Amplification And Gastric Cancer Progression Via USP54-Mediated Deubiquitination Of PLK4

1
1. scibot 06 Jan 2023
  
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  RRID: AB_444306
  
  DOI: 10.1016/j.isci.2022.105745
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9800543/
Oct 2022
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Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA

1
1. scibot 25 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.033
  
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sciencedirect.com/science/article/pii/S1097276522009546
Jul 2022
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Catalytic cycling of human mitochondrial Lon protease

1
1. scibot 27 Jul 2022
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.str.2022.06.006
  
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sciencedirect.com/science/article/pii/S0969212622002696
Jun 2022
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A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader

1
1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.chembiol.2022.05.003
  
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sciencedirect.com/science/article/pii/S2451945622001659
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Insights into the Mechanism of Human Deiodinase 1

1
1. scibot 01 Jun 2022
  
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  RRID:AB_444306
  
  DOI: 10.3390/ijms23105361
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9141512/
Mar 2022
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Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors

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K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy

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Selective autophagy controls innate immune response through a TAK1/TAB2/SH3PX1 axis

1
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A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue

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Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth

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Aberrant RNA methylation triggers recruitment of an alkylation repair complex

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Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

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  DOI: 10.1038/s41467-021-24687-4
  
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Untitled document

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  DOI: 10.1210/en.2018-01048
  
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FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection

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A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants

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Methylation of dual-specificity phosphatase 4 controls cell differentiation

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STIM1 long and STIM1 gate differently TRPC1 during store-operated calcium entry

1
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  HIS.H8
  
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Untitled document

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HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

1
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  DOI: 10.1016/j.celrep.2019.05.096
  
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May 2021
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A BIN2-GLK1 Signaling Module Integrates Brassinosteroid and Light Signaling to Repress Chloroplast Development in the Dark

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sciencedirect.com/science/article/pii/S153458072030976X
Apr 2021
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Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering

2
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  DOI: 10.1016/j.chembiol.2020.04.004
  
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Developing Covalent Protein Drugs via Proximity-Enabled Reactive Therapeutics

1
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sciencedirect.com/science/article/pii/S0092867420306231
Feb 2021
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Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration

1
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Dec 2020
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Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions

1
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sciencedirect.com/science/article/pii/S2211124720315278
Oct 2020
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Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae

1
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sciencedirect.com/science/article/pii/S002248042030634X
Sep 2020
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C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast

1
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  DOI: 10.1016/j.celrep.2020.108190
  
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APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin

1
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  AB_444306
  
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sciencedirect.com/science/article/pii/S2211124720302321
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Identification of a Structural Determinant for Selective Targeting of HDMX

1
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sciencedirect.com/science/article/pii/S0969212620301325
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Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity

1
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A Family of Argonaute-Interacting Proteins Gates Nuclear RNAi

1
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Extraction of mRNA from Stalled Ribosomes by the Ski Complex

1
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Active Lysogeny in Listeria Monocytogenes Is a Bacteria-Phage Adaptive Response in the Mammalian Environment

1
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sciencedirect.com/science/article/pii/S2211124720309372
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Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis

1
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The LKB1-like Kinase Elm1 Controls Septin Hourglass Assembly and Stability by Regulating Filament Pairing

1
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sciencedirect.com/science/article/pii/S0960982220305492
content.iospress.com content.iospress.com

The interactome of the prostate-specific protein Anoctamin 7

1
1. scibot 04 Sep 2020
  
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  anti-6 ××<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" alttext="\times" display="inline" id="S2.SS8.p2.m3"><mml:mo>×</mml:mo></mml:math> His tag
  
  DOI: 10.3233/CBM-190993
  
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content.iospress.com/articles/cancer-biomarkers/cbm190993
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Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway

1
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sciencedirect.com/science/article/pii/S2211124720300528
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Site-specific 5-hydroxy-tryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high density lipoprotein biogenesis

1
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  anti-His
  
  DOI: 10.1074/jbc.RA119.012092
  
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jbc.org/content/295/15/4836.full
Jan 2020
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HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis

1
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  AB_444306
  
  DOI: 10.1016/j.celrep.2019.05.096
  
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In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation

1
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  RRID:AB_444306
  
  DOI: 10.7554/eLife.45916
  
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Untitled document

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  RRID:AB_444306
  
  DOI: 10.1016/j.cell.2019.04.010
  
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Mitochondrial Protein Synthesis and mtDNA Levels Coordinated through an Aminoacyl-tRNA Synthetase Subunit

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1. scibot 13 Jan 2020
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.celrep.2019.03.022
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.devcel.2018.12.025
  
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FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis

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1. scibot 13 Jan 2020
  
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  RRID:AB_444306
  
  DOI: 10.1016/j.devcel.2018.12.021
  
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sciencedirect.com/science/article/pii/S1534580718311171
Nov 2018
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Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding

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1. scibot 05 Nov 2018
  
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Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0969212617303702
Nov 2017
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Sam68 Allows Selective Targeting of Human Cancer Stem Cells

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1. scibot 08 Nov 2017
  
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  Curator: @chewbeccax
  
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RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination

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1. scibot 08 Nov 2017
  
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  Curator: @Zeljana_Babic
  
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C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

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1. scibot 08 Nov 2017
  
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